Ispitivanje čvrstoće okvira ojastučenog namještaja s bočnim stranicama od drvnih ploča metodom konačnih elemenata

Comparative analysis of the strength characteristics of one-seat upholstered furniture frame with rails of Pinus Sylvestris L. and side plates of PB, OSB and PLY boards was carried out. 3D geometric model of the upholstered furniture frame was created by Autodesk Inventor Pro®. Linear static analyses were carried out by the method of finite elements (FEM) simulating light-service loading. The orthotropic material characteristics of the used materials were considered in the analyses. Two variants of corner joints in the frame (model A – staples and PVAc; model B - staples, PVAc and strengthening elements under the rail of the seat) were considered. The laboratory established coefficients of rotational stiffness of used staple corner joints in the skeleton were considered in finite element analysis (FEA). As result, the distribution of the maximum and minimum principal stresses in the 3D model of upholstered furniture frame side plates were derived and analysed. The worst failure indexes according to Tsai-Wu failure criteria were calculated at heavy-service load. The study provided database of strength values that can help in the engineering of upholstered furniture frames with side plates of PB, OSB and PLY.Provedena je usporedba svojstava čvrstoće okvira ojastučenog naslonjača s poveznicima od borovine (Pinus Sylvestris L.) i s bočnim stranicama od drvnih ploča (iverice, OSB ploče i furnirske ploče). Za potrebe ispitivanja uz pomoć programa Autodesk Inventor Pro® izrađen je 3D geometrijski model okvira ojastučenog namještaja. Linearne statičke analize provedene su metodom konačnih elemenata (FEM) uz simuliranje malog opterećenja. U analizama su uzeta u obzir svojstva ortotropnog materijala. Promatrane su dvije varijante kutnih spojeva okvira (model A – sponke i PVAc; model B – sponke, PVAc i pojačanja poveznika ispod sjedala). Analizom konačnih elemenata (FEA) razmatrani su laboratorijski utvrđeni koefi cijenti rotacijske krutosti sponki upotrijebljenih za kutne spojeve okvira. Time je dobivena i analizirana raspodjela najvećih i najmanjih glavnih naprezanja u 3D modelu bočnih stranica potkonstrukcije ojastučenog namještaja. Najlošiji indeksi loma prema Tsai-Wu kriterijima loma izračunani su pri velikim opterećenjima. Kao rezultat istraživanja dobivena je baza podataka o vrijednostima čvrstoće koja može pomoći u projektiranju okvira ojastučenog namještaja s bočnim stranicama od iverica, OSB ploča i furnirskih ploča

A Review of Big Data in Road Freight Transport Modeling: Gaps and Potentials

Road transport accounted for 20% of global total greenhouse gas emissions in 2020, of which 30% come from road freight transport (RFT). Modeling the modern challenges in RFT requires the integration of different freight modeling improvements in, e.g., traffic, demand, and energy modeling. Recent developments in \u27Big Data\u27 (i.e., vast quantities of structured and unstructured data) can provide useful information such as individual behaviors and activities in addition to aggregated patterns using conventional datasets. This paper summarizes the state of the art in analyzing Big Data sources concerning RFT by identifying key challenges and the current knowledge gaps. Various challenges, including organizational, privacy, technical expertise, and legal challenges, hinder the access and utilization of Big Data for RFT applications. We note that the environment for sharing data is still in its infancy. Improving access and use of Big Data will require political support to ensure all involved parties that their data will be safe and contribute positively toward a common goal, such as a more sustainable economy. We identify promising areas for future opportunities and research, including data collection and preparation, data analytics and utilization, and applications to support decision-making

Production of rare cycloartane saponins from Astragalus thracicus (Griseb) compared to Astragalus membranaceus (Fisch.) Bunge – native and biotechnological sources

The aim of this study is a comparative metabolomic analysis between the endangered species Astragalus membranaceus and endemic species Astragalus thracicus concerning cycloartane saponins. In addition, in vitro shoots, callus, and suspension cultures of A. thracicus were successfully established to conserve the biodiversity of those endemic species and to increase the amount of produced saponins. The comparison was made according to the quantity of cycloartane saponins astragaloside I (1), astragaloside II (2), and astragaloside IV (4) to the reference standards for the same compounds by UHPLC-HRESI-MS analysis. The in vitro root cultures of A. thracicus reached two folds higher amounts of saponins (1.50 mg/g DW (1), 1.01 mg/g DW (2), and 0.91 mg/g DW (3)) than the native root of A. thracicus (1.14 mg/g DW (1) 0.47 mg/g DW (2), 0.40 mg/g DW (3)), and up to six times higher when compared with roots A. membranaceus (0.23 mg/g DW (1), 0.18 mg/g DW (2) and 0.05 mg/g DW (3))

The Wellesley News (01-19-1933)

https://repository.wellesley.edu/news/1936/thumbnail.jp

The Crystal Structure of the Reduced, Zn2+-Bound Form of the B. subtilis Hsp33 Chaperone and Its Implications for the Activation Mechanism

AbstractThe bacterial heat shock protein Hsp33 is a redox-regulated chaperone activated by oxidative stress. In response to oxidation, four cysteines within a Zn2+ binding C-terminal domain form two disulfide bonds with concomitant release of the metal. This leads to the formation of the biologically active Hsp33 dimer. The crystal structure of the N-terminal domain of the E. coli protein has been reported, but neither the structure of the Zn2+ binding motif nor the nature of its regulatory interaction with the rest of the protein are known. Here we report the crystal structure of the full-length B. subtilis Hsp33 in the reduced form. The structure of the N-terminal, dimerization domain is similar to that of the E. coli protein, although there is no domain swapping. The Zn2+ binding domain is clearly resolved showing the details of the tetrahedral coordination of Zn2+ by four thiolates. We propose a structure-based activation pathway for Hsp33

Arylnaphthalene lignans with a focus Linum species: a review on phytochemical, biotechnological and pharmacological potential

Lignans are a large group of dimeric phenylpropanoids with a long and distinguished history of medicinal use in the ancient cultures of many peoples. The two main groups, -aryltetralin and arylnaphthalene lignans, are leading compounds with important pharmacological properties and a wide range of biological activities. While the first group is well studied mainly for the production of podophyllotoxin, for arylnaphthalene lignans, the data on the availability of a sustainable resource for their production is are still insufficient. The Linum genus, comprising approximately 180 species, is notable for its arylnaphthalene lignans production like justicidin B and isojusticidin B. The pharmacological potential of arylnaphthalene lignans includes cytotoxic, antiviral, anti-inflammatory and antiprotozoal effects. The review highlights the use of biotechnology by in vitro cultures for optimising lignan production. Structural elucidation of novel lignans underscores the ongoing diversity and potential discoveries in this botanical domain, providing an important additional information of arylnaphthalene lignans

Non-cash payments : Role of the banking sector in non-cash payments settlement: Case of CIBANK

The purpose of this paper was to reveal the nature, role, place and importance of non-cash payments in the worldwide economic life with an emphasis on the Bulgarian reality. It clarifies the causes and consequences of the changing climate of the national payments system in accordance with the increased modern demands for its performance. All of this was viewed through the prism of the banks as mediators for money and with regard to the ongoing economic crisis. The study also presents the various forms of non-cash payments and the current niche for Bulgarian banks in the market for electronic payments. The methodology used was to first clarify the general terms and participants in the cash and non-cash money market, then to narrow those down to the Bulgarian financial subjects and economic circumstances and legal supervision, and in the end focuses on the non-cash services at the point of sale. The analysis was carried out as part of a project of the Bulgarian bank CIBANK in an attempt to provide valuable information on the areas on which to approach the potential customers of the point-of-sale electronic services. The study underlined the main benefits of utilizing POS systems from the point of view of businesses and from the point of view of the end-users of the POS as the latter were found to have direct implication on the first. Among key aspects that were found were better supply and demand visibility, gathering of intelligent consumer specific data, faster checkout speed and improved customer satisfaction