Perioperative outcomes of bipolar energy instruments in total laparoscopic hysterectomy

Objectives: To compare conventional and advanced bipolar energy instruments in terms of perioperative outcomes in patients who underwent total laparoscopic hysterectomy (TLH).  Material and methods: The data of 101 patients who underwent TLH between June 2017 and December 2018 for benign gynecological disorders were analyzed retrospectively. Conventional bipolar forceps (Robi forceps) were used in 37 patients and advanced bipolar instruments (LigaSure) were used in 64 patients. Data about the characteristics of the patients, operation time, estimated blood loss, length of hospital stay and other perioperative outcomes were compared.  Results: The mean ages of the patients in the conventional bipolar and LigaSure groups were 47.6 ± 6.5 and 48.1 ± 7 years, respectively (p > 0.05). There was no statistically significant difference between the two groups with regard to all other patient characteristics; body mass index, parity, previous pelvic operation and indications of hysterectomy (p > 0.05). The mean operation time (41 ± 13.2 vs 37 ± 11.5 min), estimated intraoperative blood loss (70 ± 22 vs 65 ± 21 mL) and absolute change in hemoglobin (-1.23 ± 1.12 vs -1.11 ± 1.14 g/dL) were slightly higher in the conventional bipolar group. However, there was no statistical significance with respect to these differences between the groups (p > 0.05).  Conclusions: Our findings indicate that a conventional bipolar system is as safe and effective as LigaSure, and it may be used as an alternative option for patients undergoing TLH in low-income hospitals

Biosorption of Cr(VI) by free and immobilized Pediastrum boryanum biomass: equilibrium, kinetic, and thermodynamic studies

15th International Symposium on Toxicity Assessment (ISTA) -- JUL 03-08, 2011 -- City Univ Hong Kong, Hong Kong, PEOPLES R CHINAWOS: 000306790200053PubMed ID: 22374187The biosorption of Cr(VI) from aqueous solution has been studied using free and immobilized Pediastrum boryanum cells in a batch system. The algal cells were immobilized in alginate and alginate-gelatin beads via entrapment, and their algal cell free counterparts were used as control systems during biosorption studies of Cr(VI). The changes in the functional groups of the biosorbents formulations were confirmed by Fourier transform infrared spectra. The effect of pH, equilibrium time, initial concentration of metal ions, and temperature on the biosorption of Cr(VI) ion was investigated. The maximum Cr(VI) biosorption capacities were found to be 17.3, 6.73, 14.0, 23.8, and 29.6 mg/g for the free algal cells, and alginate, alginate-gelatin, alginate-cells, and alginate-gelatin-cells at pH 2.0, which are corresponding to an initial Cr(VI) concentration of 400 mg/L. The biosorption of Cr(VI) on all the tested biosorbents (P. boryanum cells, alginate, alginate-gelatin, and alginate-cells, alginate-gelatin-cells) followed Langmuir adsorption isotherm model. The thermodynamic studies indicated that the biosorption process was spontaneous and endothermic in nature under studied conditions. For all the tested biosorbents, biosorption kinetic was best described by the pseudo-second-order model.PROCORE-France/Hong Kong Joint Res Scheme, Croucher Fdn, KC Wong Educ Fd

The parameters to estimate postoperative severe complications classified through Clavien-Dindo after upper abdominal surgery in patients with primary and recurrent ovarian cancer

Objectives: The more surgical effort and performing extensive upper abdominal surgery (UAS) are often required to accomplish the highest rates of optimally cytoreduction in patients with ovarian cancer. Nonetheless, the rate of complications increases with extensive surgery. We have studied the upper abdominal surgery complications by Clavien-Dindo Classification (CDC) and analyzed parameters affecting post-operative severe complications classified through Clavien-Dindo. Material and methods: A retrospective cohort of patients diagnosed with epithelial ovarian cancer from January 1st 2009 to April 30th 2016 was evaluated. Patients who underwent at least one UAS procedure with or without optimal cytoreduction for epithelial ovarian cancer (stage IIIC–IV or recurrent) were included. Postoperative complications were recorded according to the Clavien-Dindo Classification. Results: In total, 58 patients were included. There were 120 UAS procedures performed on the 58 patients. Diaphragm peritonectomy was the most performed surgery (50%, 29/58), and then the other UAS procedures were liver surgery (39.7%, 23/58), cholecystectomy (24.1%, 14/58), splenic surgery (24.1%, 14/58), full-thickness diaphragm resection (22.4%, 13/58), pancreatic surgery (19%, 11/58), resection of tumor from porta hepatis (17.2%, 10/58), celiac lymph node excision (8.6%, 5/58), partial gastrectomy (1.7%, 1/58), respectively. Thirteen patients (22.4%) had post-operative grade 3–5 complications according to CDC within 30 days after surgery. Conclusions: This current study demonstrated that the addition of extensive upper abdominal surgery procedures were not associated with increased postoperative severe complications in patients with recurrent or advanced ovarian cancer. These procedures are safe and feasible for patients in need and also can be performed with acceptable mortality and morbidity

A multi-objective mathematical model for the electric vehicle charging station placement problem in urban areas

As the popularity of electric vehicle (EV) technology continues to develop rapidly, so does the demand for charging stations, which are expected to be the main source of energy for electric vehicles in smart cities. An ideal charging network of stations would facilitate easy access to charging stations for drivers by ensuring that there is always a station nearby, and do that with the minimum number of stations to reduce infrastructure costs. Motivated by striking a balance between these two, we propose a novel multi-objective model for the EV charging station placement problem under a renewed constraint of a network that aims to make it easy for drivers to reach a station from anywhere in a city within a reasonable distance. We apply the model to Eskisehir in Turkey and then solved it with the weighted sum scalarisation method. We demonstrate and discuss the results which show practicality of the model

INVESTIGATE THE POTENTIAL OF BEING JEOPARK OF NARMAN CANYON (NARMAN-ERZURUM) AND PREPARE OF JEOPARK INVENTORY

Narman Canyon, located within the boundaries of the Country of Erzurum Narman, covers an area of 63 km(2). Narman Canyon covered with Pliyo-Quaternary sediments. Oldest formation in the valley is Yoldere Formation. Buyukdere formation is in accordance with this unit, old Alluvial Fan sediments is over this units. Over all of these units are ancient alluviums

The levels of oxidative stress biomarkers of liver and mammary tissues of apparently mice.

Objective: In the present study, the levels of antioxidant systems such as glucose-6-phosphate dehydrogenase (G6PDH), catalase (CAT), superoxide dismutase (SOD), glutathione-S-transferase (GST) and, also reduced glutathione (GSH) in liver and breast tissues were examined in order to obtain basal data for subsequent toxicological investigations. Additionally, the level of thiobarbituric acid reactive substance (TBARS) was measured in liver and breast tissues as an index of lipid peroxidation. Materials and Methods: Sixty-six apparently healthy mice (36 male, 30 female) had normal liver and breast tissues (histopathological data) were taken into the study. The tissues were homogenised with ice-cold 1.15 % KCI. The activities of antioxidant enzymes, the levels of GSH and TBARS were measured as spectrophotometric in the supernatant obtained from centrifugation at 14.000 rpm. Results: The levels of antioxidant systems and TBARS in liver were significantly higher than those found in breast tissue of female and male mice (P 0.05). On the other hand, the levels of CAT, SOD, GST, GSH and TBARS in male liver except G6PDH enzyme were higher than female liver (P < 0.05). Conclusion: Results suggest that antioxidant defense of the liver tissue was higher compared to breast tissue possibly due to a compensatory response to various toxic substances in liver and thereby protects the cells against oxidative damage. [Cukurova Med J 2013; 38(1.000): 7-14

Detection of spikes with multiple layer perceptron network structures

In this work, the spikes in the electroencephalogram (EEG) signals are analyzed by using artificial neural networks (ANN). Multiple layer perceptron (MLP) networks utilizing between 3 and 15 hidden neurons are used in the network architecture. For training the MLP network backpropagation algorithm, backpropagation with adaptive learning rate, Levenberg-Marquardt (LM) algorithm, early stopping and regularization methods are used. Principal components of feature vectors obtained from 41 consecutive sample values of each peak are used for training the networks. Performances of classifiers are examined for two cases depending on both sensitivity-specificity and sensitivity-selectivity properties

Multivariate Statistics and Heavy Metals Contamination in Beach Sediments from The Sakarya Canyon, Turkey

WOS: 000312621500066The aim of the study is to determine heavy metal contents and their possible origins that represent the variability of The Sakarya Canyon coastal sediments. In addition to determine the source of heavy metals (natural and anthropogenic), simple and multivariate statistical analyses were applied to the samples. In all the samples, ignition loss ratio is between 0.01-0.09. 47.26 % of the samples, which have 0.5-0.25 mm, show very good sorting. G10, G19, G20 and G21 reflect the conditions of the irregular sedimentary environment. The heavy metals, Fe, Mg, Ti, Cr, Zn, Pb and Cu, are considered to come from near regions according to frequency histograms. By principal component analysis (PCA; factor 1: 40.911 %; factor 2: 21.558 %; factor 3: 13.548 %) and cluster analysis, heavy metals were formed three (3) groups. According to hierarchical cluster analysis, Q-type cluster at the similarity level of 50 % form three (3) different groups and they show the same features during pollution. These results reveal that they are highly reliable data for statistical data of model summary (according to the value R-2 = 100) and Anova 21 explanation value. According to maximum abundances As:G4; Ni:G7; Mg, Ti, Mn, Fe, V, Cr, Co, Nb:G13; Cu, Zr, Sn:G20; Al, Zn, Ga, Cd, Pb:G22 stations showed the highest anomaly. Influence of anthropogenic can be constituted in this region coming from port wastes, mining operations, road pollution, urban wastes and industrial wastes.Scientific Research Projects Unit of Akdeniz UniversityThe financial support of the Scientific Research Projects Unit of Akdeniz University is gratefully acknowledged

Investigation of prognostic significance of CD44 expression in women with vulvar squamous cell carcinoma

The aim of our study is to evaluate whether CD 44 isoform expression is a prognostic factor in vulvar carcinom and to correlate the expression with clinicopathological parameters. Methods: The study included 26 patients diagnosed with invasive squamous cell vulvar cancer. The data of patients were obtained from the oncology follow-up records and the hospital database. The haemotoxylene & eosin stained preparates of the cases were removed from the archives and re-evaluated by examination of the slides under a light microscope. The preparates of the patients were evaluated separately according to the extent and intensity of staining and the combined score applied with the immunohistochemical method in the anti-CD44 antibody in the epithelium and the stroma. Results: When the CD44 epithelial staining intensity and staining combined scores of the patients were examined according to other clinicopathological parameters, a statistically significant difference was found between the groups in terms of tumour grade, differentiation, age, lymph node positivity, and survival rates (p [Med-Science 2019; 8(4.000): 774-781

Contribution of myeloperoxidase and inducible nitric oxide synthase to pathogenesis of psoriasis

YALCIN, OMER T./0000-0001-5626-1881WOS: 000389786000006PubMed: 28035220Introduction: Histological changes of psoriasis include invasion of neutrophils into the epidermis and formation of Munro abscesses in the epidermis. Neutrophils are the predominant white blood cells in circulation when stimulated; they discharge the abundant myeloperoxidase (MPO) enzyme that uses hydrogen peroxide to oxidize chloride for killing ingested bacteria. Aim: To investigate the contribution of neutrophils to the pathogenesis of psoriasis at the blood and tissue levels through inducible nitric oxide synthase (iNOS) and MPO. Material and methods: A total of 50 adult patients with a chronic plaque form of psoriasis and 25 healthy controls were enrolled to this study. Serum MPO and iNOS levels were measured using ELISA method. Two biopsy specimens were taken in each patient from the center of the lesion and uninvolved skin. Immunohistochemistry was performed for MPO and iNOS on both normal and psoriasis vulgaris biopsies. Results: While a significant difference between serum myeloperoxidase levels were detected, a similar statistical difference between participants in the serum iNOS levels was not found. in immunohistochemistry, intensely stained leukocytes with MPO and intensely staining with iNOS in psoriatic skin was observed. Conclusions: Neutrophils in psoriasis lesions are actively producing MPO and this indirectly triggers the synthesis of iNOS. Targeting of MPO or synthesis of MPO in the lesion area may contribute to development of a new treatment option