Professional education in tourism: problems of the regional level

The article reveals the main problems of professional education in the sphere of tourism at the regional leve

Development of a module for obtaining biometric parameters for authentication in medical systems

Automated identification using biometric authentication has a high level of protection of personal data, as it evaluates the physical parameters and characteristics of a particular person, which makes such access control more reliable. Due to the Covid-19 pandemic, the medical system is unprepared for such trials, where the incidence is increasing daily, causing a shortage of medical staff and facilities for diagnosis or emergency therapy. Therefore, today the urgent task is to develop automated medical systems that will expand the use of medical equipment and thus reduce the burden on medical staff. Automated systems must have a high degree of protection that will ensure the reliability of personal data during diagnostic procedures, excluding the influence of human factors of medical staff (fatigue, inattention that contributes to a number of errors that significantly affect the final plan of care). Existing medical devices and systems can be upgraded using the module for obtaining biometric parameters for authentication. An important step in the development of a module to automate the authentication process is the analysis, selection and integration of all necessary components for the assembly of the electrical system of the device

Coulomb drag between two spin incoherent Luttinger liquids

In a one dimensional electron gas at low enough density, the magnetic (spin) exchange energy $J$ between neighboring electrons is exponentially suppressed relative to the characteristic charge energy, the Fermi energy $E_F$. At non-zero temperature $T$, the energy hierarchy $J \ll T \ll E_F$ can be reached, and we refer to this as the spin incoherent Lutinger liquid state. We discuss the Coulomb drag between two parallel quantum wires in the spin incoherent regime, as well as the crossover to this state from the low temperature regime by using a model of a fluctuating Wigner solid. As the temperature increases from zero to above $J$ for a fixed electron density, the $2k_F$ oscillations in the density-density correlations are lost. As a result, the temperature dependence of the Coulomb drag is dramatically altered and non-monotonic dependence may result. Drag between wires of equal and unequal density are discussed, as well as the effects of weak disorder in the wires. We speculate that weak disorder may play an important role in extracting information about quantum wires in real drag experiments.Comment: 19 pages, 10 figure

Positioning of Russia in the world ranking competitiveness of travel and tourism

This article analyzes positions of Russia in world tourist space on the basis of the tourism and travel competitiveness rating provided by the World Economic Forum. At the heart of rating lies The Travel and Tourism Competitiveness Index (TTCI) calculated on the basis of fourteen indicators grouped in four subindexe

Sociological diagnostics of crowdsourcing technology in the practice of regional management

The article proposes a methodology for identifying and analyzing the technology of crowdsourcing, examines the main stages of the formation, and analyzes the implementation of crowdsourcing technology into the practice of regional managemen

Исследование содержания ионов K⁺, Ca⁺⁺, Na⁺ в крови человека определенных возрастных групп

У статті наведено аналіз методів визначення електролітів у крові, проаналізовано переваги та недоліки цих методів. Головним недоліком є те, що більша частина вимагає для проведення аналізу забір крові у пацієнта. Метод неінвазивного визначення формули крові метаболічних і гемодинамічних показників гомеостазу проводиться без забору крові, але має суттєвий недолік – чутливість теплових датчиків, що розташовують у біологічно активних точках. Незначне зміщення при їх установці призводить до великих помилок вимірювання, що, в свою чергу, спотворює параметри біохімічного аналізу в кінцевому результаті. Обґрунтовано метод вдосконалення функціональної діагностики із застосуванням кардіомоніторингу.In the article is resulted an analysis over the methods of determination of electrolytes is brought in blood, advantages and lacks of these methods are analysed. A main defect is that greater part requires for realization of analysis the fence of blood for a patient. The method of uninvasion determination the formula of blood is metabolic and haemodynamic indexes of homoeostasis is conducted without the fence of blood but has a substantial defect – sensitiveness of thermal sensors which dispose in bioactive points. Little displacement during setting results in the large errors of measuring which in turn will show a wrong biochemical analysis in end-point. A method of perfection of functional diagnostics are offered and reasonable with application in cardiomonitoring.В статье приведен анализ методов определения электролитов в крови, проанализированы преимущества и недостатки этих методов. Главным недостатком является то, что большая часть требует для проведения анализа забор крови у пациента. Метод неинвазивного определения формулы крови метаболических и гемодинамических показателей гомеостаза проводится без забора крови, но имеет существенный недостаток – чувствительность тепловых датчиков, которые располагают в биологически активных точках. Незначительное смещение при установке приводит к большим ошибкам измерения, которое, в свою очередь, будет показывать неправильный биохимический анализ в конечном результате. Обоснован метод совершенствования функциональной диагностики с применением кардиомониторинга

Regenerative therapy for the nonhealing cutaneous wounds

Regenerative medicine therapy is inspired by current research advances in cellular biology, genetic engineering, synthetic biology, material sciences and so far contributes to the traditional therapy, making resistant diseases curable. Nowadays, chronic wound healing is possible due to cell-based regenerative technologies and recent non-cell therapeutic approaches. Here we review clinical applications of human stem cells, as well as cellular and tissue products as alternatives to the traditional therapy of non-healing wounds. The cell-based technologies for tissue regeneration and bioengineering utilize stem cells that are either injected into bloodstream or positioned directly into the target area. Cell-free regeneration technologies require either stem cell products, i.e., secretomes or their separate components, extracellular membrane vesicles, or tissue products. The stem cell therapies are designed to replace critically absent components of wounded or degenerative tissue. The stem cell secretome can promote the repair of damaged tissues independently of parent cells. Extracellular membrane vesicles mimic and recapitulate the mechanisms of stem cells in tissue regeneration and therefore might be promising for chronic wound and severe burns healing. The tissue products traditionally remain efficient wound healing remedies along with emerging advanced technologies. © 2018 I. V. Orlovska et al

Use of a recombinant human follicle-stimulating hormone:recombinant human luteinizing hormone (r-hFSH:r-hLH) 2:1 combination for controlled ovarian stimulation during assisted reproductive technology treatment: A real-world study of routine practice in the Russian Federation

Two observational studies in the Russian Federation described patient demographics/clinical decision for treatment with recombinant human follicle-stimulating hormone:recombinant human luteinizing hormone (r-hFSH:r-hLH) 2:1 combination for ovarian stimulation (OS) during assisted reproductive technology (ART) and outcomes, respectively. The first (prospective) study enrolled 500 patients. After post-hoc regrouping to assign patients to discrete groups, 378 (75.6%) met the local Russian label for an r-hFSH:r-hLH 2:1 combination, 105 (21%) were treated according to other physician preference, and 17 (3.4%) met only the ESHRE Bologna criteria for a poor ovarian response. The clinical pregnancy rate per cycle was 30.4%. A total of 158/175 (90.3%) women achieving clinical pregnancy in the prospective study participated in the second (retrospective) study. The live birth rate per cycle was 25.8%. No new safety concerns were reported. These results support the use of the r-hFSH:r-hLH 2:1 combination in patients with a poor/suboptimal response to OS for ART treatment in the Russian Federation

Efficacy decametoxin in vitro for quick inactivation of respiratory coronavirus

Despite the fact that specific prophylaxis agents have already been widely introduced into medical practice in all countries of the world, and antiviral drugs are being developed and are undergoing the first stages of clinical trials, SARS-CoV-2 continues to spread in the human population. In this regard, an urgent medical problem today is the expansion of the arsenal of effective disinfectants and antiseptics, the action of which would be aimed at the rapid and complete inactivation of extracellular coronavirus, which is a very important element in controlling the spread of COVID-19. The aim of the study was to evaluate the ability of decamethoxin to have a virucidal effect against SARS-COV-2 and other human coronaviruses on the model of respiratory coronavirus IBV (infectious bronchitis virus) with an exposure time of 30, 60 and 120 seconds. Classical and modern virological research methods were used in the work: determination of the cytotoxic effect of decamethoxin in cell culture by the effect on their viability, cultivation, accumulation and determination of the infectious titer of IBV by cytopathic action in cell culture; assessment of the virucidal effect of decamethoxin by the suspension method to determine the residual infectious titer of the virus in cell culture by the method of limiting dilutions. The effectiveness of the antiseptic decamethoxin from the group of quaternary ammonium compounds was studied in relation to the prototype strain of the IBV (infection bronchitis virus) coronavirus family in vitro. It has been established that an isotonic solution of decamethoxin at a concentration of 100 μg/ml completely inactivates 3.0 lg(TCD50/0.1 ml) of the prototype respiratory coronavirus strain with a clinically significant contact time of 30–120 seconds at room temperature(18–24 оС). Decamethoxine has been shown to be an effective, fast-acting antiseptic capable of completely inactivating a prototype coronavirus strain. The revealed virucidal properties of decamethoxine in pharmacopoeially significant concentrations in relation to coronavirus allow to recommend it as an antiseptic in the development of methods for non-specific prevention of coronavirus infection in humans