Polyps of the gallbladder: retrospective analysis of 33 cases

Amaç: Safra kesesi polipleri , safra kesesi mukozasından köken alan lezyonlardır. Bu çalısmada, klinigimizde preoperatif safra kesesi polibi tanısı alarak cerrahi girisim uygulanan olgular patolojik tanıları ile tartısılmakta ve cerrahi endikasyon koyduracak kriterlerin tanımlanması amaçlanmaktadır. Materyal-Metod: Klinigimizde Ocak 1995 ile Haziran 2003 tarihleri arasında preopeeratif safra kesesi polibi tanısı alan olgular demografik özellikleri, klinik ve abdominal ultrasonografi bulguları, yapılan cerrahi tedavi, histopatolojik tanıları, morbidite ve mortalite açısından retrospektif olarak degerlendirildi. Bulgular: Kolesistektomi yapılan 1420 olgunun otuzüçü de (%2,3) preoperatif safra kesesi polibi tanısı almıstır. Karın agrısı en sık rastlanılan semptom idi.Tüm olgulara abdominal ultrasonografi ile tanı konulmus olup görüntülemede, 3 olguda sesil, 30 olguda ise pediküllü polip bulunurken, 7 olguda ek olarak kolelithiasis saptandı. Tedavide 8 olguda laparoskopik, 25 olguda ise açık olarak kolesistektomi yapıldı. Histopatolojik incelemede ; 16 olguda sadece kolelithiasis ve kronik kolesistit, 14 olguda kolesterol polibi, 2 olguda adenomatöz polip, 1 olguda ise adenokarsinom saptandı. Sonuç: Safra kesesi poliplerinde cerrahi tedavi, tüm semptomatik, beraberinde kolelitiasis olan, polip boyutu 10 mmgeçen ve ultrasonografik olarak malignite riski tasıyan olgularda yapılmalıdır.Aim: The nature of polypoid lesions of the gallbladder is difficult to define before operation, and surgical indications still remain controversial. The aim of this study was to identfy surgical indications for polypoid lesion of the gallbladder with regarding their ultrasonographic histopathological findings and indications. Material-Methods: Between 1995 and June 2003, the patients with preoperative diagnosis of gallbladder polyp were evaluated retrospectively according to their demographic findings, clinical symptoms, abdominal ultrasonography results, surgical treatment and pathology . Results: The incidence of preoperative gallbladder polyp diagnosis was 2,3% (33/1420) in cholecystectomized patients. The most common symptom was abdominal pain. In abdominal ultrasonography used for diagnosis in all patient, the polyps were sessile in 3 cases and pedunculated in 30 cases. Also cholelithiasis was coexist with polyp in 7 cases ultrasonographically. Cholecystectomy was made laparoscopically in 8 patients and others were with open technique. In histopathological assesment, the results were as only cholelithiasis and chronic cholecystitis / 16 cases, cholesterol polyp / 14 cases, adenoma / 2 cases and adenocarcinoma / 1 case. Conclusion: Surgery is the choice of treatment in all symptomatic patients and the cases having polyps with a size of greater than 10 mm as well as the cases carrying malignant features ultrasonographically

Genotype, production system and sex effects on fatty acid composition of meat from goat kids

Two trials were performed to assess the meat fatty acid profile of goat kids from different genotypes, production systems and sex. In the first trial, genotype effect was determined in 24 suckling male kids from Turkish Saanen, Maltese and Gokceada breeds. In the second trial, male and female Gokceada Goat kids were used to compare the effect of extensive and semi-intensive production systems on fatty acid composition of meat. Significant genotype effect was observed in the percentages of myristic acid (C14:0), palmitic acid (C16:0), oleic acid (C18:1 n-9), linolenic acid (C18:3 n-3), arachidonic acid (C20:4 n-6) and docosahexaenoic acid (C22:6 n-3), despite no differences on the ratios of polyunsaturated fatty acids to saturated fatty acids (PUFA/SFA) and n-6/n-3 (P>0.05). The effect of production system had also significant effects on fatty acids, but sex only influenced significantly stearic acid (C18:0), C18:1 n-9 and C18:3 n-3 fatty acids and total PUFA level and PUFA/SFA ratio. This study confirms that dairy breeds are prone to produce higher levels of unsaturated fatty acids in their muscle. Meanwhile, meat from Gokceada goat kids, which is one of the indigenous breeds in Turkey, had similar PUFA/SFA and n-6/n-3 ratios to Turkish Saanen and Maltase

Anadolu Mandalarında Subklinik Mastitis Prevalansı ve Hastalığın Etkileri

&nbsp;The aim of this study was to calculate the prevalence and changes in milk due to subclinical mastitis in Anatolian buffaloes, and the financial losses caused by the disease. The material of the study consisted of milk samplesobtained from 96 udder lobes belonging to a total of 24 female Anatolian buffaloes raised in Kayseri. Milk sampleswere collected from four farms in March 2021 and the infection status of the milk was evaluated by examining the California Mastitis Test (CMT) and somatic cell count (SHS). According to the results, 5 buffalo (20.8%) and 8 lobes (8.3%)were found to be infected and mean SHS value was found as 182500 cell/ml. The fat of infected animals milk decreased by 27.4% (P&lt;0.05) and the milk yield decreased by 12.6%, if the disease was not treated, it was calculatedthat a loss of 1140 TL (138 $) will occur in a lactation, and if treated, this loss can be reduced by 951.5 TL (115$). Inconclusion, it was revealed that the prevalence of subclinical mastitis in Anatolian buffaloes raised in Kayseri is high(20.08%), infection significantly reduces milk fat, especially in terms of quality, producers should educate in terms ofdiseases and pay more attention to hygiene, otherwise subclinical mastitis will cause significant losses and reduce theirprofitability</p

Effects of propylene glycol used at different doses in Akkaraman lambs rations on metabolism-related parameters and liver gene and protein expression during different feeding periods

This study aimed to investigate the metabolic effects of propylene glycol (PG) over 60, 90, and 120 days in lambs. Seventy-two weaned male lambs were allocated into three groups: control (Con), PG1.5 (1.5 mL/kg live weight0.75), and PG3 (3 mL/kg live weight0.75). Blood samples were collected at the beginning and slaughter days. Biochemical parameters (glucose, triglycerides, ALT, AST, LDH, BUN, and insulin) and gene and protein levels of peroxisome proliferator activated receptor gamma (PPARγ), diacylglycerol o-acyltransferase 1 (DGAT1), carbohydrate responsive element binding protein (ChREBP), and sterol regulatory element binding transcription factor 1c (SREBP-1c) in the liver were determined. Glucose in PG1.5 was increased on Day 60, while significant differences were observed in biochemical parameters except for insulin on the 60, 90, and 120 days. Biochemical parameters such as ALT, AST, LDH, and BUN increased over time, while triglycerides decreased. DGAT1 gene and protein levels were lower, while SREBP-1c and PPARγ were higher in PG groups on Day 60. While SREBP-1c was lower in PG1.5, ChREBP was higher in PG3 on Day 90. PPARγ, DGAT1, and ChREBP were upregulated in PG3 on Day 120. Positive correlations were found between proteins. The long-term use of PG in lambs did not have detrimental effects on metabolism. The study provides valuable insights into the molecular mechanisms underlying the metabolic effects of PG in lambs, shedding light on its potential applications in lamb production