Dynamic Hydrostatic Pressure Promotes Differentiation of Human Dental Pulp Stem Cells

The masticatory apparatus absorbs high occlusal forces, but uncontrolled parafunctional or orthodontic forces damage periodontal ligament (PDL), cause pulpal calcification, pulp necrosis and tooth loss. Morphology and functional differentiation of connective tissue cells can be controlled by mechanical stimuli but effects of uncontrolled forces on intra-pulpal homeostasis and ability of dental pulp stem cells (DPSCs) to withstand direct external forces are unclear. Using dynamic hydrostatic pressure (HSP), we tested the hypothesis that direct HSP disrupts DPSC survival and odontogenic differentiation. DPSCs from four teenage patients were subjected to HSP followed by assessment of cell adhesion, survival and recovery capacity based on odontogenic differentiation, mineralization and responsiveness to bone morphogenetic protein-2 (BMP-2). HSP down-regulated DPSC adhesion and survival but promoted differentiation by increasing mineralization, in vivo hard tissue regeneration and BMP-2 responsiveness despite reduced cell numbers. HSP-treated DPSCs displayed enhanced odontogenic differentiation, an indication of favorable recovery from HSP-induced cellular stress

Ferromagnetism in Mn doped GaAs due to substitutional-interstitial complexes

While most calculations on the properties of the ferromagnetic semiconductor GaAs:Mn have focussed on isolated Mn substituting the Ga site (Mn$_{Ga}$), we investigate here whether alternate lattice sites are favored and what the magnetic consequences of this might be. Under As-rich (Ga-poor) conditions prevalent at growth, we find that the formation energies are lower for Mn$_{Ga}$ over interstitial Mn (Mn$_i$).As the Fermi energy is shifted towards the valence band maximum via external $p$-doping, the formation energy of Mn$_i$ is reduced relative to Mn$_{Ga}$. Furthermore, under epitaxial growth conditions, the solubility of both substitutional and interstitial Mn are strongly enhanced over what is possible under bulk growth conditions. The high concentration of Mn attained under epitaxial growth of p-type material opens the possibility of Mn atoms forming small clusters. We consider various types of clusters, including the Coulomb-stabilized clusters involving two Mn$_{Ga}$ and one Mn$_i$. While isolated Mn$_i$ are hole killers (donors), and therefore destroy ferromagnetism,complexes such as Mn$_{Ga}$-Mn$_i$-Mn$_{Ga}$) are found to be more stable than complexes involving Mn$_{Ga}$-Mn$_{Ga}$-Mn$_{Ga}$. The former complexes exhibit partial or total quenching of holes, yet Mn$_i$ in these complexes provide a channel for a ferromagnetic arrangement of the spins on the two Mn$_{Ga}$ within the complex. This suggests that ferromagnetism in Mn doped GaAs arises both from holes due to isolated Mn$_{Ga}$ as well as from strongly Coulomb stabilized Mn$_{Ga}$-Mn$_i$-Mn$_{Ga}$ clusters.Comment: 7 figure

Ultra-Thin Silver Films obtained by Sequential Quench-Anneal Processing

We have used the two-step growth technique, quench condensing followed by an anneal, to grow ultra thin films of silver on glass substrates. As has been seen with semiconductor substrates this process produces a metastable homogeneous covering of silver. By measuring the in situ resistance of the film during growth we are able to see that the low temperature growth onto substrates held at 100 Kelvin produces a precursor phase that is insulating until the film has been annealed. The transformation of the precursor phase into the final, metallic silver film occurs at a characteristic temperature near 150K where the sample reconstructs. This reconstruction is accompanied by a decrease in resistance of up to 10 orders of magnitude

Semirigid Geometry

We provide an intrinsic description of $N$-super \RS s and $TN$-\SR\ surfaces. Semirigid surfaces occur naturally in the description of topological gravity as well as topological supergravity. We show that such surfaces are obtained by an integrable reduction of the structure group of a complex supermanifold. We also discuss the \s moduli spaces of $TN$-\SR\ surfaces and their relation to the moduli spaces of $N$-\s\ \RS s.Comment: 29p

Search for NN-decoupled dibaryons using the process pp→γγXpp \to \gamma \gamma X below the pion production threshold

The energy spectrum for high energy $\gamma$-rays ($E_\gamma \geq 10$ MeV) from the process $pp \to \gamma \gamma X$ emitted at $90^0$ in the laboratory frame has been measured at an energy below the pion production threshold, namely, at 216 MeV. The resulting photon energy spectrum extracted from $\gamma-\gamma$ coincidence events consists of a narrow peak at a photon energy of about 24 MeV and a relatively broad peak in the energy range of (50 - 70) MeV. The statistical significances for the narrow and broad peaks are 5.3$\sigma$ and 3.5$\sigma$, respectively. This behavior of the photon energy spectrum is interpreted as a signature of the exotic dibaryon resonance $d^\star_1$ with a mass of about 1956 MeV which is assumed to be formed in the radiative process $pp \to \gamma d^\star_1$ followed by its electromagnetic decay via the $d^\star_1 \to pp \gamma$ mode. The experimental spectrum is compared with those obtained by means of Monte Carlo simulations.Comment: 14 pages, LaTex, 6 eps-figures, accepted for publication in Phys.Rev.

Trees with Given Stability Number and Minimum Number of Stable Sets

We study the structure of trees minimizing their number of stable sets for given order $n$ and stability number $\alpha$. Our main result is that the edges of a non-trivial extremal tree can be partitioned into $n-\alpha$ stars, each of size $\lceil \frac{n-1}{n-\alpha} \rceil$ or $\lfloor \frac{n-1}{n-\alpha}\rfloor$, so that every vertex is included in at most two distinct stars, and the centers of these stars form a stable set of the tree.Comment: v2: Referees' comments incorporate

Quasinormal modes of a Schwarzschild black hole surrounded by free static spherically symmetric quintessence: Electromagnetic perturbations

In this paper, we evaluated the quasinormal modes of electromagnetic perturbation in a Schwarzschild black hole surrounded by the static spherically symmetric quintessence by using the third-order WKB approximation when the quintessential state parameter $w_{q}$ in the range of $-1/3<w_{q}<0$. Due to the presence of quintessence, Maxwell field damps more slowly. And when at $-1<w_{q}<-1/3$, it is similar to the black hole solution in the ds/Ads spacetime. The appropriate boundary conditions need to be modified.Comment: 6 pages, 3 figure

Time and Amplitude of Afterpulse Measured with a Large Size Photomultiplier Tube

We have studied the afterpulse of a hemispherical photomultiplier tube for an upcoming reactor neutrino experiment. The timing, the amplitude, and the rate of the afterpulse for a 10 inch photomultiplier tube were measured with a 400 MHz FADC up to 16 \ms time window after the initial signal generated by an LED light pulse. The time and amplitude correlation of the afterpulse shows several distinctive groups. We describe the dependencies of the afterpulse on the applied high voltage and the amplitude of the main light pulse. The present data could shed light upon the general mechanism of the afterpulse.Comment: 11 figure

Transition from tunneling to direct contact in tungsten nanojunctions

We apply the mechanically controllable break junctions technique to investigate the transition from tunneling to direct contact in tungsten. This transition is quite different from that of other metals and is determined by the local electronic properties of the tungsten surface and the relief of the electrodes at the point of their closest proximity. The conductance traces show a rich variety of patterns from the avalanche-like jump to a mesoscopic contact to the completely smooth transition between direct contact and tunneling. Due to the occasional absence of an adhesive jump the conductance of the contact can be continuously monitored at ultra-small electrode separations. The conductance histograms of tungsten are either featureless or show two distinct peaks related to the sequential opening of spatially separated groups of conductance channels. The role of surface states of tungsten and their contribution to the junction conductance at sub-Angstrom electrode separations are discussed.Comment: 6 pages, 6 figure