34 research outputs found
A unified treatment of single component replacement models
- Author
- A Ran
- B Fox
- BD Sivazlian
- C Valdez-Flores
- EJ Muth
- Hans Frenk
- HW Block
- JBG Frenk
- JJ McCall
- M Berg
- M Berg
- M Berg
- M Berg
- M Loeve
- M Mikolas
- M Zijlstra
- M Zijlstra
- Marcel Kleijn
- R Cleroux
- R Dekker
- RB Ash
- RE Barlow
- RL Schaeffer
- Rommert Dekker
- RW Wolff
- S Asmussen
- S Weeren Van
- SM Ross
- T Nakagawa
- V Makis
- V Makis
- W Feller
- WP Pierskalla
- YS Sherif
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1996
- Field of study
In this paper we discuss a general framework for single component replacement models. This framework is based on the regenerative structure of these models and by using results from renewal theory a unified presentation of the discounted and average finite and infinite horizon cost models is given. Finally, some well-known replacement models are discussed, and making use of the previous results an easy derivation of their cost functions is presented
Expression of auxin-binding protein1 during plum fruit ontogeny supports the potential role of auxin in initiating and enhancing climacteric ripening
- Author
- A Lang
- A Ohmiya
- A Ohmiya
- A Tromas
- A Varki
- A. Mahboob
- AM Bregoli
- AM Jones
- AM Jones
- AM Jones
- AN Miller
- C Feckler
- C Thomas
- CM Lazarus
- EJ Woo
- F Ziliotto
- FEG Scherer
- H LĂŒthen
- H Nielsen
- I El-Sharkawy
- I El-Sharkawy
- I El-Sharkawy
- I El-Sharkawy
- I El-Sharkawy
- I. El-Sharkawy
- J Friml
- JB Biale
- JG Chen
- JG Chen
- JJ Giovannoni
- JM Bauly
- JM Dunwell
- JM LeliĂšvre
- JM Thornton
- K Yin
- K. Abubaker
- KM David
- KM David
- L Meisel
- L Trainotti
- M AugustĂ
- M Christian
- M Löbler
- M Quint
- M. Bouzayen
- MA Kukuruzinska
- N Dharmasiri
- N Leblanc
- N Leblanc
- PJ Davies
- R Hertel
- RE Litz
- RM Napier
- RM Napier
- RM Napier
- RM Napier
- S Kepinski
- S Shimomura
- S. Jayasankar
- S. Sherif
- SF Altschul
- T Anai
- WD Teale
- YS Kim
- ZX Hou
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2012
- Field of study
Auxin-binding protein1 (ABP1) is an active element involved in auxin signaling and plays critical roles in auxin-mediated plant development. Here, we report the isolation and characterization of a putative sequence from Prunus salicina L., designated PslABP1. The expected protein exhibits a similar molecular structure to that of well-characterized maize-ABP1; however, PslABP1 displays more sequence polarity in the active-binding site due to substitution of some crucial amino-acid residues predicted to be involved in auxin-binding. Further, PslABP1 expression was assessed throughout fruit ontogeny to determine its role in fruit development. Comparing the expression data with the physiological aspects that characterize fruit-development stages indicates that PslABP1 up-regulation is usually associated with the signature events that are triggered in an auxin-dependent manner such as floral induction, fruit initiation, embryogenesis, and cell division and elongation. However, the diversity in PslABP1 expression profile during the ripening process of early and late plum cultivars seems to be due to the variability of endogenous auxin levels among the two cultivars, which consequently can change the levels of autocatalytic ethylene available for the fruit to co-ordinate ripening. The effect of auxin on stimulating ethylene production and in regulating PslABP1 was investigated. Our data suggest that auxin is involved in the transition of the mature green fruit into the ripening phase and in enhancing the ripening process in both auxin- and ethylene-dependent manners thereafter
A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)
- Author
- Abbott TE
- Abdallah RI
- Abdel-Aal IR
- Abdelmonem SA
- Abdo WF
- Abellan AN
- AbellĂĄn AN
- AbellĂĄn AN
- AbellĂĄn AN
- Abrams ST
- Ackerley C
- Acuña M
- Adda M
- Adhikari NK
- Adriano G
- Adrie C
- Affatato R
- Affatato R
- Afonso-Rivero D
- Agarossi A
- Agarwal LK
- Ageeva T
- Agrawal R
- Aguayo-DeHoyos E
- Aguilar AL
- Aguilar-Alonso E
- Aguilar-Alonso E
- Aguilar-Alonso E
- Aguirregabyria M
- Ahmadnia E
- Ahn C
- Ahn JY
- Ahn JY
- Ahn MY
- Ahn MY
- Aitken LM
- Akalaev R
- Akbarzadeh A
- Akcan-Arikan A
- Akhlagh SH
- Akhtar N
- AKI Research Group
- Akiduki N
- Akin S
- Akizuki N
- Akkoc T
- Ala-Kokko T
- Alanio A
- Albaiceta GM
- Albaladejo P
- Alberto F
- Albuisson E
- Alcala MA
- AlcĂĄzar L
- Aldabo-Pallas T
- Aldana NN
- Aldecoa C
- AlegrĂa L
- Alejandro R
- Alejo GC
- Alejos RM
- Alexandrova E
- Algarte R
- Algarte R
- Algieri I
- Algora-Weber A
- Alhamdi Y
- Aliaga FA
- Aliberti S
- Alkan A
- Almudena PM
- Almudevar PM
- Almudevar PM
- Almudévar PM
- Altıntas ND
- Alvarez J
- Alves SC
- Alzola LM
- Amargianitakis V
- Amaro R
- Amato MB
- Ambler M
- Amerongen MP
- Amininejad T
- Amor LL
- Amorim V
- Anand RK
- Andersen LW
- Andersson S
- Andoh K
- Andrade AH
- Andrade AH
- Andrade AH
- Andrade G
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- Andreis DT
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- Antonelli M
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- Antonio C
- Antonucci E
- AntĂłn DG
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- Appiani F
- Aquevedo A
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- Araujo NJ
- Araujo VF
- ARIAM registry of adult cardiac surgery
- ARIAM-ANDALUCIA
- Arias CC
- Arias N
- Arias-Verdu MD
- Arias-Verdu MD
- Arias-Verdu MD
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- Arslantas MK
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- Aslanian P
- Aspide R
- Asyralyyeva G
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- Athapattu P
- Atkins G
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- Aublanc M
- Augustin P
- Augustin P
- Auquier P
- Avilés-Jurado FX
- Avramidis V
- Ayala LY
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- Azevedo JC
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- Balsera B
- Banderas-Bravo ME
- Banderas-Bravo ME
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- Bangstad IL
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- Baquero JD
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- CAPCRI Study
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- Charitidou E
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- Chen YS
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- Cheng CC
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- Cheng YJ
- Chernyshuk S
- Chevret S
- Chhor V
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- Chiou KR
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- Chiumello D
- Chiurazzi C
- Chiurazzi C
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- Chok L
- Cholkraisuwat J
- Cholley B
- Chondropoulos S
- Chou W
- Chouris I
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- Christopher KB
- Chrétien JM
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- Chumaev A
- Chung CR
- Churchill K
- Chytas A
- Cinel I
- Cinnella G
- Citerio G
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- Clavel M
- Clemente EA
- Clermont G
- Cleyet M
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- Colino L
- Collange O
- Colombo A
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- da Silva SL
- da Silva VZ
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- Dalhuisen A
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- Damas P
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- Das Neves A
- David H
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- de Abreu MG
- De Backer A
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- De La Fuente-Martos C
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- de Molina FJ
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- Del Olmo R
- Del Rosario CG
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- Delgado CP
- Delgado MJ
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- Di Gravio V
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- Dilly MP
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- Dimitroulakis K
- Dimitrov BD
- Dimitrov BD
- Dimopoulou IK
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- Divatia JV
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- Doherty P
- Dolset RA
- Dominguez JP
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- DubĂł S
- Dudas G
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- Durrant J
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- DĂaz PV
- DĂŒnser MW
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- E YY
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- EcheverrĂa JG
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- Egginton JS
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- El Adawy AS
- El Hamid MA
- El Hossainy R
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- ENVIN-HELICS Study Group
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- FernĂĄndez MV
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- FerrĂłn FR
- Fiks T
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- FilekoviÄ S
- Filho CA
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- Filho CA
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- FINNRESUSCI Study Group
- Fischer G
- Fleischmann E
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- Floccard B
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- Follin A
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- Fong KY
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- Fontana V
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- Frigeni B
- Frithiof R
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- FROG ICU Investigators
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- GETGAG Working Group
- GETGAG/SEMICYUC
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- Hernandis V
- HernĂĄndez A
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- Hodgson LE
- Hodgson LE
- Hofmeijer J
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- Hom H
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- Hopkins PA
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- Hualde JB
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- Huang WC
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- Huang WC
- Huang WC
- Hubbard A
- Huber W
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- Hull AM
- Hung CY
- Hung WT
- Hung WT
- Hung WT
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- Husheer SL
- Hutchings S
- Hutchison R
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- Hwang GS
- Ibañes PG
- Ibsen M
- Idei M
- Idei M
- Idone FA
- Iesu E
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- Iglesias-Santiago A
- Ignacio ML
- Iida A
- Iijima H
- Ilan R
- Ilyina V
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- Inaloo S
- Ince C
- Iotti GA
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- IPREA Study Group
- Irazabal JM
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- Ishimatsu S
- Itenov TS
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- Izawa M
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- Jaber S
- Jacky A
- Jacobs FM
- Jacques T
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- Jang BH
- Janotka M
- Janotka M
- Janotka M
- Jansen D
- Jansen N
- Japan Septic Disseminated Intravascular Coagulation (JSEPTIC DIC) study group
- Jardim JJ
- Jardim M
- Jareño A
- Javadpour S
- Jayasinghe S
- Jean-Baptiste S
- Jean-Baptiste S
- Jensen AE
- Jensen JU
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- Jeong IY
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- Jian Z
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- Jiménez GJ
- Jo YH
- Joachim J
- Jochmans S
- John G
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- Jonas M
- Jonas M
- Jones C
- Joshi R
- Joshi V
- Jovaisa T
- JSEPTIC (Japanese Society of Education for Physicians and Trainees in Intensive Care) Clinical Trial Group
- Juan WC
- Juanas CA
- Judickas S
- Juez A
- Juliarena A
- Jun IG
- Jun IG
- Jung K
- Jung KW
- Junior JM
- Kaczirek K
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- Kalenka A
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- Kaminsky GE
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- Kashyap R
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- Komuro T
- Kondili E
- Kongpolprom N
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- Kumari BK
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- Kurmukov IA
- Kurth T
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- Labra C
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- Sprung CL
- St Georgeâs University of London
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- Student Research Committee - Shiraz University of Medical Sciences
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- Yoshihiro S
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- Ălvarez JT
- Ălvarez-Lerma F
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
Meeting abstrac
A comprehensive overview of radioguided surgery using gamma detection probe technology
- Author
- A Agrawal
- A Ayhan
- A Ayhan
- A Bembenek
- A Bembenek
- A Benevento
- A Blom
- A Chella
- A Cuschieri
- A Gil-Moreno
- A Gonfiotti
- A Gruaz-Guyon
- A Hubalewska
- A Hubalewska-Dydejczyk
- A HĂ€cker
- A Iagaru
- A Lal
- A Leibovitz
- A Luini
- A Meyer
- A Mussa
- A Muxi
- A Patel
- A Renda
- A Sardi
- A Sardi
- A Schattner
- A Seal
- A Sherif
- A Sherif
- A Thor
- A Thor
- A Thor
- A Woznick
- AA Dunne
- AC Barros
- AC Federico
- AC Morris Jr
- AC van Akkooi
- ACG Mitchell
- AD Hill
- AF KovĂĄcs
- AF KovĂĄcs
- AH Chakera
- AJ Bilchik
- AJ Bilchik
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- AK Buck
- AM Cohen
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- B Akduman
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- B Esmaeli
- B Frerich
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- B Li
- B Meller
- B Meller
- B Selverstone
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- B Zulfikaroglu
- BD Collier
- BD Todd
- BG Liu
- BJ Sickle-Santanello
- BJ Van Royen
- BK Kroon
- BL Franc
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- BO Helal
- BR Haugen
- C Altgassen
- C Atinkaya
- C Bastide
- C Curtet
- C De Cicco
- C De Cicco
- C de Labriolle-Vaylet
- C Duport
- C Levenback
- C Levenback
- C Merisio
- C Michl
- C Mojzisik
- C Murphy
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- C Ohyama
- C Ulmer
- C Ulmer
- C Wang
- CA Hoefnagel
- CA Nieroda
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- T Negele
- T Sera
- T Shimotake
- T Tajima
- T Tiourina
- T van Mesdag
- TE Ind
- TJ Selman
- TL Klausen
- TM Daniel
- U Ăhrvall
- V Argenzio
- V Argenzio
- V Descheemaeker
- V Lavoué
- V Lavoué
- VE Strong
- VG Johnson
- VH Ho
- W JĂ€ger
- W Kitagawa
- W Meinhardt
- W Rzyman
- WA Waddington
- WB Al-Refaie
- WC Barker
- WC Harvey
- WC Scurry
- WE Burak
- WE Burak Jr
- WJ Schirmer
- WK Stadelmann
- WL Tse
- XG Sheng
- Y Bhanot
- Y Delpech
- Y Kitagawa
- Y Kitagawa
- Y Kitagawa
- Y Kitagawa
- Y Kitagawa
- Y Kitagawa
- Y Saikawa
- Y Sanli
- Y Uenosono
- Y Uenosono
- YA Chung
- YJ Lee
- YK Chen
- YQ Wang
- YS Lin
- ZR Shi
- Publication venue
- BioMed Central
- Publication date
- 01/01/2009
- Field of study
The concept of radioguided surgery, which was first developed some 60 years ago, involves the use of a radiation detection probe system for the intraoperative detection of radionuclides. The use of gamma detection probe technology in radioguided surgery has tremendously expanded and has evolved into what is now considered an established discipline within the practice of surgery, revolutionizing the surgical management of many malignancies, including breast cancer, melanoma, and colorectal cancer, as well as the surgical management of parathyroid disease. The impact of radioguided surgery on the surgical management of cancer patients includes providing vital and real-time information to the surgeon regarding the location and extent of disease, as well as regarding the assessment of surgical resection margins. Additionally, it has allowed the surgeon to minimize the surgical invasiveness of many diagnostic and therapeutic procedures, while still maintaining maximum benefit to the cancer patient. In the current review, we have attempted to comprehensively evaluate the history, technical aspects, and clinical applications of radioguided surgery using gamma detection probe technology
Twelve-month observational study of children with cancer in 41 countries during the COVID-19 pandemic
- Author
- Ababneh H
- Abantanga FA
- Abbas AS
- Abdel-Maboud M
- Abdelhafeez H
- Abdelsalam S
- Abdelwahab M
- Abdessamad E
- Abdul-Mumin A
- Abdulai AB
- Abdulkarim A
- Abdulwahed E
- Abib SDV
- Abodest A
- Abou Chaar MK
- Abu Teir SN
- Abualkher K
- Abukhalaf SA
- AbuZa'nouneh F
- Adam E
- Adegboye MO
- Adekanmbi AF
- Ademola-Popoola DS
- Ademuyiwa AO
- Adeyeye AA
- Adhnon A
- Adly M
- Adwi M
- Afolaranmi OJ
- Ahammed MT
- Ahmad Z
- Ahmed A
- Ahmed A
- Ahmed M
- Ajayi EI
- Aji N
- Ajinkpang S
- Akinoso A
- Akinsete AM
- Akova E
- Akter M
- Akter T
- Al Ayed A
- Al Balushi Z
- Al Bolowi N
- Al Bulushi I
- Al Fayez FN
- Al Hamadani O
- Al Shamsi A
- Al Sharqi A
- Al Sharqi J
- Al Shraideh A
- Al Sibai S
- Al-Agele Y
- Al-Basiti A
- Al-Dabaibeh S
- Al-Furais S
- Al-Rawas AAS
- Alakaloko FM
- Alalawi Y
- Alam MA
- Alameer E
- Alamre A
- Albanna AAM
- Alelayan AF
- Alfa Y
- Alhendy M
- Ali AM
- Ali N
- Ali S
- Alias H
- Aliyu T
- Alkhalil MAA
- Allam AR
- Almasri M
- Almihashhish MMF
- AlMirza A
- Almjersah A
- Almowafy RM
- Alnajjar R
- Alrahawy MMA
- AlShabibi AS
- Alshahri M
- Alshamikh MS
- Altaf S
- Ameh EA
- Amira G
- Amirali A
- Ammouze I
- Anwar A
- Ara Z
- Aremu A
- Arshad M
- Asaduzzaman M
- Ashwinee A
- AsifIqbal M
- Atef M
- Au D
- Axiaq A
- Ayasra F
- Aydogmus E
- Ayman A
- Azab MA
- Azeez SA
- Aziz DAA
- Aziz TT
- Azzam A
- Azzam AY
- Baddourah RM
- Badran YS
- Baertschiger RM
- Bahaa A
- Bahaaeldin M
- Bajaj A
- Bamidele OO
- Bandyopadhyay S
- Banu T
- Barola H
- Bascarevic V
- Basher AKMK
- Bassiony M
- Bdurrzzaq A
- Becktell K
- Belkacem B
- Bell N
- Benaouda H
- Benkhial FS
- Bhatti W
- Bhullar KK
- Biala M
- Bimpong KA
- Bode CO
- Boettcher M
- Bogdanovic I
- Bonna M
- Bonsaana GB
- Bouderbala A
- Bouhuwaish A
- Brachini G
- Brar A
- Brown BJ
- Brown R
- Burzeiza EM
- Buyukkapu S
- Bvulani B
- Bwala KJ
- Byrne MHV
- Cakmak G
- Calvagna V
- Carlesse FADC
- Carrolan E
- Casey A
- Chaoui G
- Charuvila S
- Chaubey D
- Chitnis M
- Christison-Lagay E
- Chylinska A
- Cicerchia P
- Cirillo B
- Coelho SD
- Cooper S
- Cozzi D
- Craig BT
- Crespo MD
- Crow K
- Danfodiyo U
- Daniel S
- Dawud B
- de Carvalho LG
- de Carvalho RV
- de Oliveira EP
- de Souza FKM
- Deeb MA
- Der EM
- Dhiman J
- Diz FL
- Do Bom-Sucesso M
- Dobs M
- Dominic C
- Dreimann M
- Drid B
- Drucker M
- Dukundane A
- Dutta R
- Ebada MA
- Effendi I
- Egbuchulem KI
- Ekwunife OH
- El Chazli Y
- El Kassas M
- El Refaee E
- El-Qurneh O
- Elbahnasawy M
- Eldaly U
- Elebute OA
- Elfiky M
- Elhadi M
- Elhaj NOY
- Elhassan MMA
- Elkaoune Y
- Elmandouh O
- Elmandouh R
- Elshenawy A
- Erhabor J
- Erwee D
- Etchill EW
- Fadel S
- Fahmawee T
- Fan JD
- Fanelli MCA
- Faried M
- Fatungase OM
- Fayngor R
- Fehintola AB
- Ferman SE
- Festus K
- Frosch KH
- Fuseini HY
- Galea N
- Gallardo MTP
- Galli-Tsinopoulou A
- Gallo G
- Gandhi S
- Garrigo MM
- Gawrieh B
- Gentle L
- Ghamgh R
- Ghamry MAM
- Ghandour K
- Ghattaura H
- Ghosh D
- Ghozy S
- Goke O
- Gomes P
- Gounni M
- Govind V
- Govindarajan KK
- Grujicic D
- Guillen G
- Gupta M
- Guzlan A
- Hager EI
- Haider F
- Hajar B
- Hamam O
- Hamdan A
- Hamid HKS
- Hamilton E
- Hamizi K
- Han WSP
- Hanafy E
- Harky A
- Harrison I
- Hasanuzzaman M
- Hassanin M
- Hattor KA
- Hatzipantelis E
- Hemlae H
- Hessissen L
- Heuer A
- Hicdonmez T
- Holail MM
- Hraib M
- Humad H
- Hussain SNF
- Ibelli T
- Ibrahim AB
- Ibrahim KOO
- Ibrahim RB
- Idros R
- Ihediwa GC
- Ikechukwu O
- Ikeda A
- Ilic R
- Imran FA
- Irungu EM
- Islam N
- Islam S
- Ismail RMJ
- Jacobsen AS
- Jain R
- Jaisingh DN
- Jasim D
- Jibrin B
- Jindal B
- Johari N
- John B
- John MJ
- Jones T
- KaderAlsaeiti S
- Kadir MY
- Kakkar S
- Kala S
- Kalra G
- Kamboj S
- Kara Y
- Karagiannidis G
- Karim S
- Karplus G
- Karthigeyan M
- Karunanithi G
- Kayal S
- Kebudi R
- Kendirlioglu BC
- Khan M
- Khan M
- Khan MR
- Khan R
- Khayyam N
- Khernane N
- Khoury V
- Kleinman E
- Kloeber JA
- Kopke L
- Kpiniong MJ
- Kumar V
- Kumar V
- Kumari P
- Kunfah SMP
- Kwarteng PG
- Labib A
- Ladipo-Ajayi O
- Laghari FA
- Laila H
- Lakhoo K
- Lal DR
- Lami M
- Lapolla P
- Latiff ZA
- Lau D
- Lawal TA
- Lazic I
- Leon JLG
- Levinson R
- Lim YY
- Lima FFD
- Lo WB
- Lobo F
- Loh AHP
- Loh CK
- Lopez S
- Lorabi S
- Lukong CS
- Luyt J
- Madan R
- Madasu A
- Madhusudanan S
- Mahal H
- Mahalik SK
- Malika M
- Mamdouh K
- Martin B
- Masoud FM
- Masoud HM
- Massoud JG
- Matei AC
- Mathew J
- Matola B
- Mazloum A
- Mbwele B
- McClafferty K
- Mehmood A
- Melamed D
- Meneghini S
- Meyer J
- Michael V
- Mijalcic R
- Milicevic M
- Mingoli A
- Mitul AR
- Mohindra S
- Molino JA
- Monteiro J
- Monteiro JM
- Morshed AKMA
- Mortada AS
- Moses O
- Moujtahid H
- Moussa A
- Mshelbwala PM
- Mughal A
- Muhammad S
- Muma K
- Muma S
- Munezero D
- Murphy M
- Musa KM
- Musa KO
- Musiu P
- Muthukumar A
- Nabi A
- Nadeem A
- Nadeem K
- Nagras S
- Nah SA
- Nahar K
- Najman T
- Nambi G
- Naredi BK
- Nasef RMM
- Nasir AA
- Nastasovic T
- Nath UK
- Nathani P
- Nauhaus H
- Nautiyal H
- Nay S
- Nazari A
- Nesrine A
- Ng YJ
- Ngongola A
- Nguma I
- Nitschke C
- Nri-Ezedi CA
- Nuhu-Koko A
- Nunes S
- Nwatah VE
- Nweze KD
- O'Sullivan BJ
- Obadaini OO
- Obat M
- Ochieng L
- Offiong U
- Ogundele IO
- Ogundoyin OO
- Ogunsua OO
- Ojha BK
- Okunlola AI
- Olalekan AL
- Olaosebikan R
- Olori S
- Olulana ID
- Omokanye KO
- Omran A
- Oni O
- Osuigwe AN
- Owen RL
- Oyesakin AB
- Ozair A
- Ozdemir GN
- Paasche C
- Pachl M
- Padilha MAC
- Pagaduan AL
- Pancharatnam R
- Parwani D
- Patel A
- Patil NR
- Patil P
- Patrick FA
- Paunovic A
- Peter N
- Peters NJ
- Pillarisetti S
- Piplani R
- Portela L
- Priemel M
- Pulock OS
- Qasem AG
- Qatora M
- Qayyum Z
- Qureshi TI
- Ragab S
- Rahim F
- Rahim N
- Rahman LOA
- Rahman SMR
- Rahmoun R
- Rahul SK
- Raj R
- Rajkumar KS
- Rana AN
- Rana MM
- Raza MR
- Reiter A
- Rhee D
- Robinson D
- Roseline NM
- Roth AS
- Royyuru S
- Ruzgar NM
- Saada B
- Saadeldin AM
- Sakar M
- Saleem A
- Saleem R
- Saleh A
- Salehi M
- Sallam I
- Salloum H
- Salman G
- Salunke P
- Samad L
- Sambandan K
- Samir A
- Sapienza P
- Saracoglu A
- Saracoglu KT
- Sayed F
- Sayomi OT
- Scepanovic V
- Schuelke MR
- Sehrawat A
- Seyi-Olajide JO
- Shabani MM
- Shater W
- Shelft M
- Sherief M
- Sherif A
- Sheth M
- Shikha A
- Shinondo P
- Shirke M
- Sholadoye TT
- Shou B
- Siegel A
- Simpson R
- Singh KK
- Singh S
- Singh V
- Smith C
- Smith T
- Solimam ESA
- Souad B
- Sriram S
- Stangenberg M
- Stanimirovic A
- Suleiman DE
- Sultan I
- Suresh V
- Suroy A
- Taha AO
- Tahir A
- Tahir S
- Taibat IT
- Tawel H
- Tawheed A
- Taylor EH
- Tebha SS
- Temiye EO
- Testi AM
- ThankGod NO
- Thompson N
- Togarepi N
- Tolani MA
- Tragiannidis A
- Tripathi M
- Tsotridou E
- Turk K
- Twaha A
- Ukoha K
- Ullrich S
- Umar AM
- Umar AM
- Umeh EO
- Umuroglu T
- Valetopoulou A
- Vasquez JEM
- Velasco P
- Viezens L
- Vojcek A
- Waleed K
- White O
- Wilson S
- Wong JHL
- Wright K
- Yahia G
- Yahya FS
- Yassaad OM
- Yasser A
- Yhoshu E
- Yip SS
- Yousf AME
- Yusof NM
- Zahid S
- Zaman ASK
- Zambon M
- Zani A
- Zarrish J
- Zekkour MA
- Zerizer Y
- Zia N
- Zubaidi SA
- Zuberi H
- Zuberi HK
- Publication venue
- place:BRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND
- Publication date
- 01/01/2022
- Field of study
Introduction Childhood cancer is a leading cause of death. It is unclear whether the COVID-19 pandemic has impacted childhood cancer mortality. In this study, we aimed to establish all-cause mortality rates for childhood cancers during the COVID-19 pandemic and determine the factors associated with mortality. Methods Prospective cohort study in 109 institutions in 41 countries. Inclusion criteria: children <18 years who were newly diagnosed with or undergoing active treatment for acute lymphoblastic leukaemia, non-Hodgkin's lymphoma, Hodgkin lymphoma, retinoblastoma, Wilms tumour, glioma, osteosarcoma, Ewing sarcoma, rhabdomyosarcoma, medulloblastoma and neuroblastoma. Of 2327 cases, 2118 patients were included in the study. The primary outcome measure was all-cause mortality at 30 days, 90 days and 12 months. Results All-cause mortality was 3.4% (n=71/2084) at 30-day follow-up, 5.7% (n=113/1969) at 90-day follow-up and 13.0% (n=206/1581) at 12-month follow-up. The median time from diagnosis to multidisciplinary team (MDT) plan was longest in low-income countries (7 days, IQR 3-11). Multivariable analysis revealed several factors associated with 12-month mortality, including low-income (OR 6.99 (95% CI 2.49 to 19.68); p<0.001), lower middle income (OR 3.32 (95% CI 1.96 to 5.61); p<0.001) and upper middle income (OR 3.49 (95% CI 2.02 to 6.03); p<0.001) country status and chemotherapy (OR 0.55 (95% CI 0.36 to 0.86); p=0.008) and immunotherapy (OR 0.27 (95% CI 0.08 to 0.91); p=0.035) within 30 days from MDT plan. Multivariable analysis revealed laboratory-confirmed SARS-CoV-2 infection (OR 5.33 (95% CI 1.19 to 23.84); p=0.029) was associated with 30-day mortality. Conclusions Children with cancer are more likely to die within 30 days if infected with SARS-CoV-2. However, timely treatment reduced odds of death. This report provides crucial information to balance the benefits of providing anticancer therapy against the risks of SARS-CoV-2 infection in children with cancer
ICAR: endoscopic skullâbase surgery
- Author
- Aaron G
- Aaron GP
- Abergel A
- Abouaf L
- Abrishamkar S
- Acioly MA
- Acioly MA
- Acuna RT
- Adams AS
- Adappa ND
- Aferzon M
- Agaimy A
- Agarwal A
- Aggarwal A
- Agrawal D
- Ahmed OH
- Aihara M
- Akagami R
- Alahmadi H
- Albu S
- Albu S
- Albu S
- Alexander A
- Alimohamadi M
- Almefty R
- Almeida JR
- Almeida JR
- Almeida JR
- Almeida JR
- Almeida JR
- Almeida JR
- Almeida JR
- Almond MC
- Alobaid A
- Alobid I
- Alobid I
- Alos L
- AlQahtani A
- Altay T
- Alvarez FL
- Alves MV
- AlâMamgani A
- AlâMefty O
- AlâSheibani S
- Amano K
- Amdur RJ
- Amelot A
- American Academy of Pediatrics Steering Committee on Quality Improvement and Management
- Amichetti M
- Amin SM
- Amit M
- Amit M
- Amit M
- Ammirati M
- Anari S
- Anderson D
- Anderson RL
- Andrade NA
- Andrews JC
- Anik I
- Ansa B
- Ansari M
- Antonelli AR
- Arafah BM
- Arafah BM
- Arafah BM.
- Arai A
- Arat YO
- Arbolay OL
- Ardehali MM
- Armengot M
- Arnautovic KI
- Arrer E
- Arslan HH
- Aryan HE
- Asano S
- Askoxylakis V
- Astrup J
- Awad AJ
- Awad M
- Azad TD
- Aziz KM
- Babin E
- Bachmann G
- Back L
- Backlund EO.
- Baijal V
- Balaker AE
- Ballah D
- Balzer JR
- Banks CA
- Banu MA
- Banu MA
- Banuchi VE
- Barnes L
- Baser B
- Baskin DS
- Battaglia P
- Battaglia P
- Becker AM
- Beckhardt RN
- Bedi AD
- Bedrosian JC
- Bedrosian JC
- BeerâFurlan A
- BeerâFurlan A
- Beham A
- Bejjani GK
- Bell D
- Bell RB
- Bell RB
- Berdahl JP
- Berhouma M
- Berker M
- Berker M
- Berkmann S
- Berkmann S
- Berkmann S
- BernalâSprekelsen M
- BernalâSprekelsen M
- Bernat AL
- Bertrand B
- Bhasker S
- Bhatti SN
- Bidot S
- Bills DC
- Bishop JA
- Biswas D
- Black PM
- Bleier BS
- Bleier BS
- Bleier BS
- Bleier BS
- Bleier BS
- Bloch C
- Bloch O
- Bly RA
- Boghani Z
- Bohman LE
- Bohman LE
- Bokhari AR
- Boling CC
- Bolzoni Villaret A
- Borg A
- Borghei P
- Boukheris H
- Brackmann DE
- Bradley PJ
- Branston NM
- Brastianos PK
- Bremer JW
- Bresson D
- Briet C
- Briggs RJ
- Brodie HA.
- Brown SM
- Bruchhage KL
- BruckerâDavis F
- Brunworth J
- Buchmann L
- Buerke B
- Bujawansa S
- Bumm K
- Bunin GR
- Burman P
- Butler S
- Butros SR
- ButâHadzic J
- Caballero N
- CaicedoâGranados E
- Caldarelli M
- Campbell E
- Campbell PG
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- Capatina C
- Cappabianca P
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- Cappabianca P
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- Carlson ML
- Carmel P
- Carrau RL
- Carrillo JF
- Carter KB
- Carvalho P
- Cassano M
- Castelnuovo P
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- Castelnuovo P
- Catapano G
- Cathelinaud O
- Cavalheiro S
- Cavallo LM
- Cavallo LM
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- Cavallo LM
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- Cebula H
- Ceylan S
- Ceylan S
- Ceylan S
- Chaaban MR
- Chaaban MR
- Chaaban MR
- Chaaban MR
- Chabot JD
- Chabot JD
- Chan JY
- Chan KH
- Chandler JR
- Chandra RK
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- Chapman PR
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- Chi F
- Chibbaro S
- Chibbaro S
- Chin CJ
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- Chiou SM
- Chiu AG
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- Cho JM
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- Choby GW
- Choi D
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- Chowdhury FH
- Christopherson K
- Chung TK
- Chung WY
- Ciporen JN
- Ciric I
- Ciric I
- Clark AJ
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- Clavenna MJ
- Clemenza JW
- CliffordâJones RE
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- Cobb MI
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- Colli BO
- Combs SE
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- Commins DJ
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- Costantino PD
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- Crockard HA
- Cummings BJ
- Cushing H.
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- Cutler AR
- D'Anza B
- Dagi TF
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- Dallan I
- Danesi G
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- Dedmon M
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- Dehdashti AR
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- Del Monte P
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- Demarco RC
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- Derome PJ
- Derrey S
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- Dhanasekar G
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- Di Rocco C
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- Dong H
- Drange MR
- Dubey SP
- Dulguerov P
- Durgam A
- Dusick JR
- Dusick JR
- Earwaker J
- Eboli P
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- El Morsy SM
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- Eljamel MS.
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- Eseonu CI
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- Fleischman GM
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- Yilmazlar S
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- Zuniga MG
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- Publication venue
- Publication date
- 01/07/2019
- Field of study
n/
C9orf72 Expansion Disrupts ATM-mediated Chromosomal Break Repair
- Author
- A Aguilera
- A Fradet-Turcotte
- AA Goodarzi
- Adrian Higginbottom
- AR Haeusler
- AT Noon
- C Doil
- C Meisenberg
- Callum Walker
- Chunyan Liao
- CJ Bakkenist
- D Roy
- DMA Mann
- Evangelia Karyka
- F GĂłmez-Herreros
- GJ McIntyre
- GS Stewart
- Guillaume M Hautbergue
- Ian Coldicott
- Ioannis Tsagakis
- J Cooper-Knock
- J Li
- J-H Lee
- J-I Heo
- JA Harrigan
- Jayanth Chandran
- Katherine Lewis
- Kurt J De Vos
- LA Sanz
- LV Schottlaender
- M Alagoz
- M Bohgaki
- M Castellano-Pozo
- M DeJesus-Hernandez
- M Groh
- M Tresini
- M Tresini
- Mateusz Jurga
- MB Felisbino
- ME Ashour
- Mimoun Azzouz
- Mohamed K Hassan
- NJ Rutherford
- NM Shanbhag
- P Corcia
- P Schwertman
- P-O Frappart
- Padraig J Mulcahy
- Pamela J Shaw
- PJ McKinnon
- RA McCloy
- RJ Mead
- S Difilippantonio
- S Katyal
- S-C Chiang
- Saul Herranz-Martin
- SF El-Khamisy
- SF El-Khamisy
- SG Lindquist
- Sherif F El-Khamisy
- Shih-Chieh Chiang
- Swagat Ray
- T Zu
- Tommaso Iannitti
- V Bhatia
- Vera Lukashchuk
- VV Belzil
- Waheba Elsayed
- X Wang
- Y Shiloh
- Y Wang
- Y Zhang
- Y-J Zhang
- YA Chan
- YS Davidson
- Ă YĂŒce
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 17/07/2017
- Field of study
A hexanucleotide repeat expansion represents the most common genetic cause of
amyotrophic lateral sclerosis (ALS) and frontotemporal dementia, though the
mechanisms by which the expansion cause neurodegeneration are poorly understood. We
report elevated levels of DNA/RNA hybrids (R-loops) and double-strand breaks (DSBs) in
rodent neurons, human cells, and in C9orf72-ALS patient spinal cord tissues.
Accumulation of endogenous DNA damage is concomitant with defective ATM-mediated
DNA repair signalling and accumulation of protein-linked DNA breaks. We further
reveal that defective ATM-mediated DNA repair is a consequence of p62 accumulation,
which impairs H2A ubiquitylation and perturbs ATM signalling. Adeno-associated virus-
mediated expression of C9orf72-related RNA and dipeptide repeats in the murine central
nervous system causes elevated DSBs, ATM defects, and triggers neurodegeneration.
These findings identify R-Loops, DSBs, and defective ATM-mediated repair as
pathological consequences of C9orf72 expansions, and suggest that C9orf72-linked
neurodegeneration is driven, at least in part, by genomic instability
Intracranial vessel wall MRI: a review of current indications and future applications
- Author
- A Portanova
- AA Khan
- AG van der Kolk
- AT Vertinsky
- B Gory
- B Sui
- BJ Kim
- BJ McGuinness
- C Lh
- C Sherif
- C Yuan
- C Zhu
- C-W Ryu
- CC Matouk
- CM Flis
- D-L Zhao
- D-W Yu
- DH Chun
- DM Mandell
- EC Obusez
- FK Hui
- GH Chung
- H Chen
- H Ohkuma
- H Ohkuma
- H Ota
- H Tenjin
- H Yang
- H-O Lee
- HJ Cloft
- HJ Noh
- HS Kwak
- I-C Su
- IF Klein
- IF Klein
- J Cahill
- J Kim
- J Wang
- J Yin
- J-M Kim
- J-M Kim
- J-W Chung
- JH Yu
- JK Park
- JS McNally
- JS McNally
- K Jain
- K Sakurai
- K Takano
- K-S Hong
- L Antiga
- L Zhang
- LA Crowe
- LL Mariani
- LM Mitsumori
- M Edjlali
- M Han
- M Kaminogo
- M Kurino
- M Li
- M Mossa-Basha
- M Skarpathiotakis
- M Yuan
- N Chalouhi
- N Lin
- NF Fanning
- O Naggara
- O Naggara
- P Franke
- P Schoenhagen
- P Vakil
- R Kleinloog
- RF Busse
- RH Swartz
- RR Baliga
- S Majidi
- S Park
- S Power
- S Ryoo
- S-H Ahn
- S-H Lim
- SE Kasner
- SM Kim
- T Hosoya
- T Natori
- T Nishioka
- T Pfefferkorn
- T Saam
- T Saam
- TA Bley
- TN Turan
- TR Miller
- W Ben Hassen
- W KĂŒker
- W-H Xu
- W-H Xu
- W-H Xu
- W-Q Yang
- WI Schievink
- WR Guerrero
- X-J Zhu
- Y Navalitloha
- Y Qiao
- Y Qiao
- Y Yang
- YS Kim
- Z Fan
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
A Case Study on Optimal Maintenance Interval and Spare Part Inventory Based on Reliability
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Long-term patency of complex bilobular, bisaccular, and broad-neck aneurysms in the rabbit microsurgical venous pouch bifurcation model
- Author
- Publication venue
- 'Maney Publishing'
- Publication date
- Field of study