894 research outputs found

    Characterization of the Ubiquitin C-Terminal Hydrolase and Ubiquitin-Specific Protease Families in Rice (Oryza sativa)

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    The ubiquitin C-terminal hydrolase (UCH) and ubiquitin-specific processing protease (UBP) protein families both function in protein deubiquitination, playing important roles in a wide range of biological processes in animals, fungi, and plants. Little is known about the functions of these proteins in rice (Oryza sativa), and the numbers of genes reported for these families have not been consistent between different rice database resources. To further explore their functions, it is necessary to first clarify the basic molecular and biochemical nature of these two gene families. Using a database similarity search, we clarified the numbers of genes in these two families in the rice genome, examined the enzyme activities of their corresponding proteins, and characterized the expression patterns of all OsUCH and representative OsUBP genes. Five OsUCH and 44 OsUBP genes were identified in the rice genome, with four OsUCH proteins and 10 of 16 tested representative OsUBP proteins showing enzymatic activities. Two OsUCHs and five OsUBPs were found to be preferentially expressed in the early development of rice stamens. This work thus lays down a reliable bioinformatic foundation for future investigations of genes in these two families, particularly for exploring their potential roles in rice stamen development

    Lead isotope provinciality of central North Pacific Deep Water over the Cenozoic

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    Understanding the pre-anthropogenic Pb cycle of central North Pacific deep water has attracted a lot of attention in recent years, partly because of its unique geographical location in that it is a remote gyre system characterized by high dust fluxes and sluggish overturning circulation. However, the factors controlling Pb isotope evolution in this area over the Cenozoic are still controversial and various mechanisms have been proposed in previous studies. Here we report new Pb and Nd isotope time series of four ferromanganese crusts (two from the western Pacific near the Mariana arc and the other two from the central Pacific). Together with previously published records, we discuss for the first time the significance of a persistent and systematic Pb isotopic provinciality recorded by central North Pacific crusts over the Cenozoic. We propose that globally well mixed stratosphere volcanic aerosols could contribute Pb but have not been the major factors controlling the Pb isotope distribution in the central North Pacific over time. Island arc input (and probably enhanced hydrothermal input between about 45 and 20 Ma) likely controlled the Pb isotope provinciality and evolution prior to ~20 Ma, when coeval Pb isotope records in different crusts showed large differences and atmospheric silicate dust flux was extremely low. After the Eocene, in particular after 20 Ma, Asian dust input has become an isotopically resolvable source, while island arc-derived Pb has remained important to balance the dust input and to produce the observed Pb isotope distribution in the central North Pacific during this period

    Single Crystalline Cadmium Sulfide Nanowires with Branched Structure

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    In this article, we report the synthesis of branched single crystal CdS nanowires. This branched CdS nanostructure is prepared by a simple surfactant-directing method, which is of particular interest as it uses readily available reagents and provides a convenient route to high-yield single crystal nanowires but with branched shape. These branched nanowires have an average diameter of about 40 nm and length up to several micrometers. A possible mechanism has been proposed and the addition of surfactant dodecylthiol into the two mixed-solvents would play an importance effect on the structure of the product. Based on the mechanism, by controlling the synthesis conditions, such as the ratios between the surfactant, inorganic solvent, and organic solvent, other kinds of nanostructures based on CdS nanowires were also prepared. Photoluminescence (PL) measurement reveals that the branched CdS nanowires have a strong emission at about 700 nm which might be due to its special structure

    Precision measurement of the branching fractions of J/psi -> pi+pi-pi0 and psi' -> pi+pi-pi0

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    We study the decays of the J/psi and psi' mesons to pi+pi-pi0 using data samples at both resonances collected with the BES III detector in 2009. We measure the corresponding branching fractions with unprecedented precision and provide mass spectra and Dalitz plots. The branching fraction for J/psi -> pi+pi-pi0 is determined to be (2.137 +- 0.004 (stat.) +0.058-0.056 (syst.) +0.027-0.026 (norm.))*10-2, and the branching fraction for psi' -> pi+pi-pi0 is measured as (2.14 +- 0.03 (stat.) +0.08-0.07 (syst.) +0.09-0.08 (norm.))*10-4. The J/psi decay is found to be dominated by an intermediate rho(770) state, whereas the psi' decay is dominated by di-pion masses around 2.2 GeV/c2, leading to strikingly different Dalitz distributions.Comment: 15 pages, 2 figure

    Observation of χc1\chi_{c1} decays into vector meson pairs ϕϕ\phi\phi, ωω\omega\omega, and ωϕ\omega\phi

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    Decays of χc1\chi_{c1} to vector meson pairs ϕϕ\phi\phi, ωω\omega\omega and ωϕ\omega\phi are observed for the first time using (106±4)×106(106\pm4)\times 10^6 \psip events accumulated at the BESIII detector at the BEPCII e+ee^+e^- collider. The branching fractions are measured to be (4.4±0.3±0.5)×104(4.4\pm 0.3\pm 0.5)\times 10^{-4}, (6.0±0.3±0.7)×104(6.0\pm 0.3\pm 0.7)\times 10^{-4}, and (2.2±0.6±0.2)×105(2.2\pm 0.6\pm 0.2)\times 10^{-5}, for χc1ϕϕ\chi_{c1}\to \phi\phi, ωω\omega\omega, and ωϕ\omega\phi, respectively. The observation of χc1\chi_{c1} decays into a pair of vector mesons ϕϕ\phi\phi, ωω\omega\omega and ωϕ\omega\phi indicates that the hadron helicity selection rule is significantly violated in χcJ\chi_{cJ} decays. In addition, the measurement of χcJωϕ\chi_{cJ}\to \omega\phi gives the rate of doubly OZI-suppressed decay. Branching fractions for χc0\chi_{c0} and χc2\chi_{c2} decays into other vector meson pairs are also measured with improved precision.Comment: 4 pages, 2 figure

    First Observation of the Decays chi_{cJ} -> pi^0 pi^0 pi^0 pi^0

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    We present a study of the P-wave spin -triplet charmonium chi_{cJ} decays (J=0,1,2) into pi^0 pi^0 pi^0 pi^0. The analysis is based on 106 million \psiprime decays recorded with the BESIII detector at the BEPCII electron positron collider. The decay into the pi^0 pi^0 pi^0 pi^0 hadronic final state is observed for the first time. We measure the branching fractions B(chi_{c0} -> pi^0 pi^0 pi^0 pi^0)=(3.34 +- 0.06 +- 0.44)*10^{-3}, B(chi_{c1} -> pi^0 pi^0 pi^0 pi^0)=(0.57 +- 0.03 +- 0.08)*10^{-3}, and B(chi_{c2} -> pi^0 pi^0 pi^0 pi^0)=(1.21 +- 0.05 +- 0.16)*10^{-3}, where the uncertainties are statistical and systematical, respectively.Comment: 7 pages, 3 figure

    Microstructure and mechanical properties of Cu joints soldered with a Sn-based composite solder, reinforced by metal foam

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    In this study, Ni foam, Cu coated Ni foam and Cu-Ni alloy foams were used as strengthening phases for pure Sn solder. Cu-Cu joints were fabricated by soldering with these Sn-based composite solders at 260 °C for different times. The tensile strength of pure Sn solder was improved significantly by the addition of metal foams, and the Cu-Ni alloy/Sn composite solder exhibited the highest tensile strength of 50.32 MPa. The skeleton networks of the foams were gradually dissolved into the soldering seam with increasing soldering time, accompanied by the massive formation of (Cu,Ni)6Sn5 phase in the joint. The dissolution rates of Ni foam, Cu coated Ni foam and Cu-Ni alloy foams into the Sn matrix increased successively during soldering. An increased dissolution rate of the metal foam leads to an increase in the Ni content in the soldering seam, which was found to be beneficial in refining the (Cu,Ni)6Sn5 phase and inhibiting the formation of the Cu3Sn IMC layer on the Cu substrate surface. The average shear strength of the Cu joints was improved with increasing soldering time, and a shear strength of 61.2 MPa was obtained for Cu joints soldered with Cu-Ni alloy/Sn composite solder for 60 min

    Study of χcJ\chi_{cJ} radiative decays into a vector meson

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    The decays χcJγV\chi_{cJ}\to\gamma V (V=ϕ,ρ0,ωV=\phi, \rho^0, \omega) are studied with a sample of radiative \psip\to\gamma\chi_{cJ} events in a sample of (1.06\pm0.04)\times 10^{8} \psip events collected with the BESIII detector. The branching fractions are determined to be: B(χc1γϕ)=(25.8±5.2±2.3)×106{\cal B}(\chi_{c1}\to \gamma\phi)=(25.8\pm 5.2\pm 2.3)\times 10^{-6}, B(χc1γρ0)=(228±13±22)×106{\cal B}(\chi_{c1}\to \gamma\rho^0)=(228\pm 13\pm 22)\times 10^{-6}, and B(χc1γω)=(69.7±7.2±6.6)×106{\cal B}(\chi_{c1}\to \gamma\omega)=(69.7\pm 7.2\pm 6.6)\times 10^{-6}. The decay χc1γϕ\chi_{c1}\to \gamma\phi is observed for the first time. Upper limits at the 90% confidence level on the branching fractions for χc0\chi_{c0} and \chict decays into these final states are determined. In addition, the fractions of the transverse polarization component of the vector meson in χc1γV\chi_{c1}\to \gamma V decays are measured to be 0.290.120.09+0.13+0.100.29_{-0.12-0.09}^{+0.13+0.10} for χc1γϕ\chi_{c1}\to \gamma\phi, 0.158±0.0340.014+0.0150.158\pm 0.034^{+0.015}_{-0.014} for χc1γρ0\chi_{c1}\to \gamma\rho^0, and 0.2470.0870.026+0.090+0.0440.247_{-0.087-0.026}^{+0.090+0.044} for χc1γω\chi_{c1}\to \gamma\omega, respectively. The first errors are statistical and the second ones are systematic.Comment: 8 pages, 3 figure

    Higher-order multipole amplitude measurement in ψ(2S)γχc2\psi(2S)\to\gamma\chi_{c2}

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    Using 106×106106\times10^6 ψ(2S)\psi(2S) events collected with the BESIII detector at the BEPCII storage ring, the higher-order multipole amplitudes in the radiative transition ψ(2S)γχc2γππ/γKK\psi(2S)\to\gamma\chi_{c2}\to\gamma\pi\pi/\gamma KK are measured. A fit to the χc2\chi_{c2} production and decay angular distributions yields M2=0.046±0.010±0.013M2=0.046\pm0.010\pm0.013 and E3=0.015±0.008±0.018E3=0.015\pm0.008\pm0.018, where the first errors are statistical and the second systematic. Here M2M2 denotes the normalized magnetic quadrupole amplitude and E3E3 the normalized electric octupole amplitude. This measurement shows evidence for the existence of the M2M2 signal with 4.4σ4.4\sigma statistical significance and is consistent with the charm quark having no anomalous magnetic moment.Comment: 14 pages, 4 figure

    Management of granulomatous lobular mastitis: an international multidisciplinary consensus (2021 edition)

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    Granulomatous lobular mastitis (GLM) is a rare and chronic benign inflammatory disease of the breast. Difficulties exist in the management of GLM for many front-line surgeons and medical specialists who care for patients with inflammatory disorders of the breast. This consensus is summarized to establish evidence-based recommendations for the management of GLM. Literature was reviewed using PubMed from January 1, 1971 to July 31, 2020. Sixty-six international experienced multidisciplinary experts from 11 countries or regions were invited to review the evidence. Levels of evidence were determined using the American College of Physicians grading system, and recommendations were discussed until consensus. Experts discussed and concluded 30 recommendations on historical definitions, etiology and predisposing factors, diagnosis criteria, treatment, clinical stages, relapse and recurrence of GLM. GLM was recommended as a widely accepted definition. In addition, this consensus introduced a new clinical stages and management algorithm for GLM to provide individual treatment strategies. In conclusion, diagnosis of GLM depends on a combination of history, clinical manifestations, imaging examinations, laboratory examinations and pathology. The approach to treatment of GLM should be applied according to the different clinical stage of GLM. This evidence-based consensus would be valuable to assist front-line surgeons and medical specialists in the optimal management of GLM.Improving the Ability of Diagnosis and Treatment of Difficult Disease
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