9,871 research outputs found
Aerodynamic forces of fluttering cylindrical and/or planar structures
Complexity of the phenomena of panel flutter instability has resulted in the necessity of developing separate design criteria for a variety of flow conditions and panel configurations. Vehicle panel configurations with low aspect ratios are of interest in low supersonic flow, where boundary layer effects are important
Evaluation of Interactions Between Oilfield Chemicals and Reservoir Rocks
The authors gratefully acknowledge Petroleum Technology Development Fund (PTDF) Nigeria for funding the PhD work from which the materials and results presented in this paper originated. The authors are also grateful to the Laboratory technicians in the School of Pharmacy and Life science and Gray School of arts, Robert Gordon University; and School of Engineering, University of Aberdeen for their technical support.Peer reviewedPublisher PD
Data Portraits and Intermediary Topics: Encouraging Exploration of Politically Diverse Profiles
In micro-blogging platforms, people connect and interact with others.
However, due to cognitive biases, they tend to interact with like-minded people
and read agreeable information only. Many efforts to make people connect with
those who think differently have not worked well. In this paper, we
hypothesize, first, that previous approaches have not worked because they have
been direct -- they have tried to explicitly connect people with those having
opposing views on sensitive issues. Second, that neither recommendation or
presentation of information by themselves are enough to encourage behavioral
change. We propose a platform that mixes a recommender algorithm and a
visualization-based user interface to explore recommendations. It recommends
politically diverse profiles in terms of distance of latent topics, and
displays those recommendations in a visual representation of each user's
personal content. We performed an "in the wild" evaluation of this platform,
and found that people explored more recommendations when using a biased
algorithm instead of ours. In line with our hypothesis, we also found that the
mixture of our recommender algorithm and our user interface, allowed
politically interested users to exhibit an unbiased exploration of the
recommended profiles. Finally, our results contribute insights in two aspects:
first, which individual differences are important when designing platforms
aimed at behavioral change; and second, which algorithms and user interfaces
should be mixed to help users avoid cognitive mechanisms that lead to biased
behavior.Comment: 12 pages, 7 figures. To be presented at ACM Intelligent User
Interfaces 201
Expression, Processing, and Localization of PmpD of Chlamydia trachomatis Serovar L2 during the Chlamydial Developmental Cycle
BACKGROUND: While families of polymorphic membrane protein (pmp) genes have been identified in several Chlamydia species, their function remains mostly unknown. These proteins are of great interest, however, because of their location in the outer membrane and possible role in chlamydial virulence. METHODOLOGY/PRINCIPAL FINDING: We analyzed the relative transcription of the pmpD gene, a member of the pmp gene family in C. trachomatis serovar L2, and its protein product translation and processing during the chlamydial developmental cycle. By real-time reverse transcription polymerase chain reaction, the pmpD gene was found to be upregulated at 16 to 24 four hours after infection. Using polyclonal antibodies generated against the predicted passenger domain of PmpD, we demonstrated that it is initially localized on the surface of reticulate bodies, followed by its secretion outside Chlamydia starting at 24 hours after infection. In elementary bodies, we found a approximately 157 kDa PmpD only inside the cell. Both events, the upregulation of pmpD gene transcription and PmpD protein processing and secretion, are coincidental with the period of replication and differentiation of RBs into EBs. We also demonstrated that, in the presence of penicillin, the cleavage and secretion of the putative passenger domain was suppressed. CONCLUSION/SIGNIFICANCE: Our results are in agreement with the general concept that PmpD is an autotransporter protein which is post-translationally processed and secreted in the form of the putative passenger domain outside Chlamydia at mid- to- late point after infection, coinciding with the development of RBs into EBs
Introduction to a Biological Systems Science
Biological systems analysis and biodynamic modelling of physiological and biological interrelationships in human body and mammal
Four Years of Airborne Measurements of Wildfire Emissions in California, with a Focus on the Evolution of Emissions During the Soberanes Megafire
Biomass burning is an important source of trace gases and particles which can influence air quality on local, regional, and global scales. With wildfire events increasing due to changes in land use, increasing population, and climate change, characterizing wildfire emissions and their evolution is vital. In this work we report in situ airborne measurements of carbon dioxide (CO2), methane (CH4), water vapor (H2O), ozone (O3), and formaldehyde (HCHO) from nine wildfire events in California between 2013 and 2016, which were sampled as part of the Alpha Jet Atmospheric eXperiment (AJAX) based at NASA Ames Research Center. One of those fires, the Soberanes Megafire, began on 22 July 2016 and burned for three months. During that time, five flights were executed to sample emissions near and downwind of the Soberanes wildfire. In situ data are used to determine enhancement ratios (ERs), or excess mixing ratio relative to CO2, as well as assess O3 production from the fire. Changes in the emissions as a function of fire evolution are explored. Air quality impacts downwind of the fire are addressed using ground-based monitoring site data, satellite smoke products, and the Community Multiscale Air Quality (CMAQ) photochemical grid model
Domain Formation in Finite-Time Quenches
We study the formation of domains in a continuous phase transition with a
finite-temperature quench. The model treated is the theory in two
spatial dimensions with global O(2) symmetry. We investigate this using
real-time thermal field theory, following Boyanovsky and collaborators, and
find that domain sizes appear to be smaller than those produced in an
instantaneous quench in the tree-level approximation. We also propose that a
more physical picture emerges by examining the two-point functions which do not
involve any cutoff on the short wavelength Goldstone modes.Comment: Revtex, 16 pages, 5 figures, Minor change
The Water Vapor Abundance in Orion KL Outflows
We present the detection and modeling of more than 70 far-IR pure rotational
lines of water vapor, including the 18O and 17O isotopologues, towards Orion
KL. Observations were performed with the Long Wavelength Spectrometer
Fabry-Perot (LWS/FP; R~6800-9700) on board the Infrared Space Observatory (ISO)
between ~43 and ~197 um. The water line profiles evolve from P-Cygni type
profiles (even for the H2O18 lines) to pure emission at wavelengths above ~100
um. We find that most of the water emission/absorption arises from an extended
flow of gas expanding at 25+-5 kms^-1. Non-local radiative transfer models show
that much of the water excitation and line profile formation is driven by the
dust continuum emission. The derived beam averaged water abundance is
2-3x10^-5. The inferred gas temperature Tk=80-100 K suggests that: (i) water
could have been formed in the "plateau" by gas phase neutral-neutral reactions
with activation barriers if the gas was previously heated (e.g. by shocks) to
>500 K and/or (ii) H2O formation in the outflow is dominated by in-situ
evaporation of grain water-ice mantles and/or (iii) H2O was formed in the
innermost and warmer regions (e.g. the hot core) and was swept up in ~1000 yr,
the dynamical timescale of the outflow.Comment: Accepted for publication in ApJ letters [2006 August 7] (5 pages 2,
figures, not edited
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