13 research outputs found

    Volume I. Introduction to DUNE

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    The preponderance of matter over antimatter in the early universe, the dynamics of the supernovae that produced the heavy elements necessary for life, and whether protons eventually decay—these mysteries at the forefront of particle physics and astrophysics are key to understanding the early evolution of our universe, its current state, and its eventual fate. The Deep Underground Neutrino Experiment (DUNE) is an international world-class experiment dedicated to addressing these questions as it searches for leptonic charge-parity symmetry violation, stands ready to capture supernova neutrino bursts, and seeks to observe nucleon decay as a signature of a grand unified theory underlying the standard model. The DUNE far detector technical design report (TDR) describes the DUNE physics program and the technical designs of the single- and dual-phase DUNE liquid argon TPC far detector modules. This TDR is intended to justify the technical choices for the far detector that flow down from the high-level physics goals through requirements at all levels of the Project. Volume I contains an executive summary that introduces the DUNE science program, the far detector and the strategy for its modular designs, and the organization and management of the Project. The remainder of Volume I provides more detail on the science program that drives the choice of detector technologies and on the technologies themselves. It also introduces the designs for the DUNE near detector and the DUNE computing model, for which DUNE is planning design reports. Volume II of this TDR describes DUNE\u27s physics program in detail. Volume III describes the technical coordination required for the far detector design, construction, installation, and integration, and its organizational structure. Volume IV describes the single-phase far detector technology. A planned Volume V will describe the dual-phase technology

    A systematic review and meta-analysis of risk factors associated with atopic dermatitis in Asia

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    10.1016/j.waojou.2020.100477World Allergy Organization Journal131110047

    Frontotemporal dementia and its subtypes: A genome-wide association study

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    Background: Frontotemporal dementia (FTD) is a complex disorder characterised by a broad range of clinical manifestations, differential pathological signatures, and genetic variability. Mutations in three genes-MAPT, GRN, and C9orf72-have been associated with FTD. We sought to identify novel genetic risk loci associated with the disorder. Methods: We did a two-stage genome-wide association study on clinical FTD, analysing samples from 3526 patients with FTD and 9402

    Observation of WWWWWW Production in pppp Collisions at s\sqrt s =13  TeV with the ATLAS Detector

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    International audienceThis Letter reports the observation of WWWWWW production and a measurement of its cross section using 139 fb1^{-1} of proton-proton collision data recorded at a center-of-mass energy of 13 TeV by the ATLAS detector at the Large Hadron Collider. Events with two same-sign leptons (electrons or muons) and at least two jets, as well as events with three charged leptons, are selected. A multivariate technique is then used to discriminate between signal and background events. Events from WWWWWW production are observed with a significance of 8.0 standard deviations, where the expectation is 5.4 standard deviations. The inclusive WWWWWW production cross section is measured to be 820±100(stat)±80(syst)820 \pm 100\,\text{(stat)} \pm 80\,\text{(syst)} fb, approximately 2.6 standard deviations from the predicted cross section of 511±18511 \pm 18 fb calculated at next-to-leading-order QCD and leading-order electroweak accuracy

    Observation of WWWWWW Production in pppp Collisions at s\sqrt s =13  TeV with the ATLAS Detector

    No full text
    International audienceThis Letter reports the observation of WWWWWW production and a measurement of its cross section using 139 fb1^{-1} of proton-proton collision data recorded at a center-of-mass energy of 13 TeV by the ATLAS detector at the Large Hadron Collider. Events with two same-sign leptons (electrons or muons) and at least two jets, as well as events with three charged leptons, are selected. A multivariate technique is then used to discriminate between signal and background events. Events from WWWWWW production are observed with a significance of 8.0 standard deviations, where the expectation is 5.4 standard deviations. The inclusive WWWWWW production cross section is measured to be 820±100(stat)±80(syst)820 \pm 100\,\text{(stat)} \pm 80\,\text{(syst)} fb, approximately 2.6 standard deviations from the predicted cross section of 511±18511 \pm 18 fb calculated at next-to-leading-order QCD and leading-order electroweak accuracy

    Observation of WWWWWW Production in pppp Collisions at s\sqrt s =13  TeV with the ATLAS Detector

    No full text
    International audienceThis Letter reports the observation of WWWWWW production and a measurement of its cross section using 139 fb1^{-1} of proton-proton collision data recorded at a center-of-mass energy of 13 TeV by the ATLAS detector at the Large Hadron Collider. Events with two same-sign leptons (electrons or muons) and at least two jets, as well as events with three charged leptons, are selected. A multivariate technique is then used to discriminate between signal and background events. Events from WWWWWW production are observed with a significance of 8.0 standard deviations, where the expectation is 5.4 standard deviations. The inclusive WWWWWW production cross section is measured to be 820±100(stat)±80(syst)820 \pm 100\,\text{(stat)} \pm 80\,\text{(syst)} fb, approximately 2.6 standard deviations from the predicted cross section of 511±18511 \pm 18 fb calculated at next-to-leading-order QCD and leading-order electroweak accuracy

    Observation of WWWWWW Production in pppp Collisions at s\sqrt s =13  TeV with the ATLAS Detector

    No full text
    International audienceThis Letter reports the observation of WWWWWW production and a measurement of its cross section using 139 fb1^{-1} of proton-proton collision data recorded at a center-of-mass energy of 13 TeV by the ATLAS detector at the Large Hadron Collider. Events with two same-sign leptons (electrons or muons) and at least two jets, as well as events with three charged leptons, are selected. A multivariate technique is then used to discriminate between signal and background events. Events from WWWWWW production are observed with a significance of 8.0 standard deviations, where the expectation is 5.4 standard deviations. The inclusive WWWWWW production cross section is measured to be 820±100(stat)±80(syst)820 \pm 100\,\text{(stat)} \pm 80\,\text{(syst)} fb, approximately 2.6 standard deviations from the predicted cross section of 511±18511 \pm 18 fb calculated at next-to-leading-order QCD and leading-order electroweak accuracy

    Observation of WWWWWW Production in pppp Collisions at s\sqrt s =13  TeV with the ATLAS Detector

    No full text
    International audienceThis Letter reports the observation of WWWWWW production and a measurement of its cross section using 139 fb1^{-1} of proton-proton collision data recorded at a center-of-mass energy of 13 TeV by the ATLAS detector at the Large Hadron Collider. Events with two same-sign leptons (electrons or muons) and at least two jets, as well as events with three charged leptons, are selected. A multivariate technique is then used to discriminate between signal and background events. Events from WWWWWW production are observed with a significance of 8.0 standard deviations, where the expectation is 5.4 standard deviations. The inclusive WWWWWW production cross section is measured to be 820±100(stat)±80(syst)820 \pm 100\,\text{(stat)} \pm 80\,\text{(syst)} fb, approximately 2.6 standard deviations from the predicted cross section of 511±18511 \pm 18 fb calculated at next-to-leading-order QCD and leading-order electroweak accuracy
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