Quantitative Assessment of Asbestos Fibers in Normal and Pathological Pleural Tissue—A Scoping Review

Background: pleural mesothelioma is a rare cancer in the general population, but it is more common in subjects occupationally exposed to asbestos. Studies with asbestos fiber quantification in pleural tissue are scarce: for this reason, we aimed at undertaking a scoping review to summarize the evidence provided by studies in which asbestos fibers were determined by electron microscopy (SEM or TEM) in human pleural tissues, whether normal or pathologic. Materials and methods: A scoping review of articles that quantified asbestos fibers in human pleural tissue (normal or pathologic) by electron microscopy (SEM or TEM), in subjects with asbestos exposure (if any) was performed. Results: The 12 studies selected comprised 137 cases, out of which 142 samples were analyzed. Asbestos fibers were detected in 111 samples (78%) and were below the detectable limit in 31 samples (22%). The concentration of asbestos fibers detected in the positive samples was distributed from as low as 0.01 mfgdt (millions of fibers per gram of dry tissue) up to 240 mfgdt. However, the minimum concentration of fibers overlaps in the three types of tissues (normal pleura, pleural plaque, mesothelioma) in terms of magnitude; therefore, it is not possible to distinguish a definite pattern which differentiates one tissue from the other. Conclusions: The studies included were heterogeneous as to the representativeness of the samples and analytical techniques; the possibility of false negatives must be considered. It would be desirable to systematically search for asbestos fibers to fill the knowledge gap about the presence of asbestos fibers in normal or pathological pleural tissue in order to better understand the development of the different pleural diseases induced by this mineral

Sr0.9_{0.9}K0.1_{0.1}Zn1.8_{1.8}Mn0.2_{0.2}As2_{2}: a ferromagnetic semiconductor with colossal magnetoresistance

A bulk diluted magnetic semiconductor (Sr,K)(Zn,Mn)$_{2}$As$_{2}$ was synthesized with decoupled charge and spin doping. It has a hexagonal CaAl$_{2}$Si$_{2}$-type structure with the (Zn,Mn)$_{2}$As$_{2}$ layer forming a honeycomb-like network. Magnetization measurements show that the sample undergoes a ferromagnetic transition with a Curie temperature of 12 K and \revision{magnetic moment reaches about 1.5 $\mu_{B}$/Mn under $\mu_0H$ = 5 T and $T$ = 2 K}. Surprisingly, a colossal negative magnetoresistance, defined as $[\rho(H)-\rho(0)]/\rho(0)$, up to $-$38\% under a low field of $\mu_0H$ = 0.1 T and to $-$99.8\% under $\mu_0H$ = 5 T, was observed at $T$ = 2 K. The colossal magnetoresistance can be explained based on the Anderson localization theory.Comment: Accepted for publication in EP

Critical study of the distribution of rotational velocities of Be stars; II: Differential rotation and some hidden effects interfering with the interpretation of the Vsin i parameter

We assume that stars may undergo surface differential rotation to study its impact on the interpretation of $V\!\sin i$ and on the observed distribution $\Phi(u)$ of ratios of true rotational velocities u=V/V_\rm c (V_\rm c is the equatorial critical velocity). We discuss some phenomena affecting the formation of spectral lines and their broadening, which can obliterate the information carried by $V\!\sin i$ concerning the actual stellar rotation. We studied the line broadening produced by several differential rotational laws, but adopted Maunder's expression $\Omega(\theta)=\Omega_o(1+\alpha\cos^2\theta)$ as an attempt to account for all of these laws with the lowest possible number of free parameters. We studied the effect of the differential rotation parameter $\alpha$ on the measured $V\!\sin i$ parameter and on the distribution $\Phi(u)$ of ratios u=V/V_\rm c. We conclude that the inferred $V\!\sin i$ is smaller than implied by the actual equatorial linear rotation velocity V_\rm eq if the stars rotate with $\alpha0$. For a given $|\alpha|$ the deviations of $V\!\sin i$ are larger when $\alpha<0$. If the studied Be stars have on average $\alpha<0$, the number of rotators with V_\rm eq\simeq0.9V_\rm c is larger than expected from the observed distribution $\Phi(u)$; if these stars have on average $\alpha>0$, this number is lower than expected. We discuss seven phenomena that contribute either to narrow or broaden spectral lines, which blur the information on the rotation carried by $V\!\sin i$ and, in particular, to decide whether the Be phenomenon mostly rely on the critical rotation. We show that two-dimensional radiation transfer calculations are needed in rapid rotators to diagnose the stellar rotation more reliably.Comment: To appear in A&

Influence of MWCNT/surfactant dispersions on the mechanical properties of Portland cement pastes

This work studies the reinforcing effect of Multi Walled Carbon Nanotubes (MWCNT) on cement pastes. A 0.35% solid concentration of MWCNT in powder was dispersed in deionized water with sodium dodecyl sulfate (cationic surfactant), cetylpyridinium chloride (anionic surfactant) and triton X-100 (amphoteric surfactant) using an ultrasonic tip processor. Three concentrations of each surfactant (1mM, 10mM and 100mM) were tested, and all samples were sonicated until an adequate dispersion degree was obtained. Cement pastes with additions of carbon nanotubes of 0.15% by mass of cement were produced in two steps; first the dispersions of MWCNT were combined with the mixing water using an ultrasonic tip processor to guarantee homogeneity, and then cement was added and mixed until a homogeneous paste was obtained. Direct tensile strength, apparent density and open porosity of the pastes were measured after 7 days of curing. It was found that the MWCNT/surfactants dispersions decrease the mechanical properties of the cement based matrix due to an increased porosity caused by the presence of surfactants. © Published under licence by IOP Publishing Ltd

Evaluación de cementos obtenidos por activación alcalina de ceniza de carbón con NaOH curados a bajas temperaturas

The temperature at which the alkaline activation process takes place is a significant factor in the evolution of the mechanical properties of coal ash cementitious base material. In this work, the influence of temperature (8 a 38 °C) and curing time (3 and 28 days) on the mechanical properties of the alkaline synthesis of two coal ashes was evaluated through the study of the mineralogical evolution of the cementitious phases by XRD and FTIR. We found that the type of zeolite, a synthesis product, depends on the study factors. For values above 28 °C and at least 7 days, alkalinely activated cements with compressive strength above 20 MPa were achieved. Other parameters, such as SiO2/Al2O3 ratio, percentage of unburned coal and particle-size distribution, should be taken into account in the variation of mechanical performance.La temperatura a la cual se desarrolla el proceso de activación alcalina es un factor significativo en la evolución de las propiedades mecánicas de material cementante base ceniza de carbón. En este trabajo se evaluó, a través del estudio de la evolución mineralógica de las fases cementantes por DRX y FTIR, la influencia de la temperatura (8 a 38 °C) y tiempo (3 y 28 días) de curado sobre las propiedades mecánicas de la síntesis alcalina de dos cenizas de carbón. Se encontró que el tipo de zeolita, producto de la síntesis, depende de los factores de estudio. Para valores superiores a 28 °C y mínimo 7 días, se lograron cementos activados alcalinamente con resistencias superiores a 20 MPa. Otros parámetros, como la relación SiO2/Al2O3, el porcentaje de carbón inquemado y la distribución del tamaño de partícula, se deben de tener en cuenta en la variación del desempeño mecánico

lp-Recovery of the Most Significant Subspace among Multiple Subspaces with Outliers

We assume data sampled from a mixture of d-dimensional linear subspaces with spherically symmetric distributions within each subspace and an additional outlier component with spherically symmetric distribution within the ambient space (for simplicity we may assume that all distributions are uniform on their corresponding unit spheres). We also assume mixture weights for the different components. We say that one of the underlying subspaces of the model is most significant if its mixture weight is higher than the sum of the mixture weights of all other subspaces. We study the recovery of the most significant subspace by minimizing the lp-averaged distances of data points from d-dimensional subspaces, where p>0. Unlike other lp minimization problems, this minimization is non-convex for all p>0 and thus requires different methods for its analysis. We show that if 0<p<=1, then for any fraction of outliers the most significant subspace can be recovered by lp minimization with overwhelming probability (which depends on the generating distribution and its parameters). We show that when adding small noise around the underlying subspaces the most significant subspace can be nearly recovered by lp minimization for any 0<p<=1 with an error proportional to the noise level. On the other hand, if p>1 and there is more than one underlying subspace, then with overwhelming probability the most significant subspace cannot be recovered or nearly recovered. This last result does not require spherically symmetric outliers.Comment: This is a revised version of the part of 1002.1994 that deals with single subspace recovery. V3: Improved estimates (in particular for Lemma 3.1 and for estimates relying on it), asymptotic dependence of probabilities and constants on D and d and further clarifications; for simplicity it assumes uniform distributions on spheres. V4: minor revision for the published versio

Voltage imaging reveals the dynamic electrical signatures of human breast cancer cells

Cancer cells feature a resting membrane potential (Vm) that is depolarized compared to normal cells, and express active ionic conductances, which factor directly in their pathophysiological behavior. Despite similarities to ‘excitable’ tissues, relatively little is known about cancer cell Vm dynamics. Here high-throughput, cellular-resolution Vm imaging reveals that Vm fluctuates dynamically in several breast cancer cell lines compared to non-cancerous MCF-10A cells. We characterize Vm fluctuations of hundreds of human triple-negative breast cancer MDA-MB-231 cells. By quantifying their Dynamic Electrical Signatures (DESs) through an unsupervised machine-learning protocol, we identify four classes ranging from "noisy” to “blinking/waving“. The Vm of MDA-MB-231 cells exhibits spontaneous, transient hyperpolarizations inhibited by the voltage-gated sodium channel blocker tetrodotoxin, and by calcium-activated potassium channel inhibitors apamin and iberiotoxin. The Vm of MCF-10A cells is comparatively static, but fluctuations increase following treatment with transforming growth factor-β1, a canonical inducer of the epithelial-to-mesenchymal transition. These data suggest that the ability to generate Vm fluctuations may be a property of hybrid epithelial-mesenchymal cells or those originated from luminal progenitors

Polarization discontinuity induced two-dimensional electron gas at ZnO/Zn(Mg)O interfaces: A first-principles study

The discovery of a high-mobility two-dimensional electron gas (2DEG) in wurtzite ZnO/Zn(Mg)O heterostructures is promising for applications due to the high mobility of the carriers. In this paper, we study the formation and properties of the 2DEG at ZnO/Zn(Mg)O interfaces using first-principles calculations based on hybrid density functional theory. The 2DEG arises from the polarization discontinuity at the interface between the two materials. The uncompensated bound charge at the interface gives rise to an electric field in the bulk of ZnO which confines free carriers close to the interface. We find that the type of the confined carriers is determined by the interface termination, while the amount of charge and the confinement width could be controlled by the Mg doping and the device dimensions

Gilbert Damping in Magnetic Multilayers

We study the enhancement of the ferromagnetic relaxation rate in thin films due to the adjacent normal metal layers. Using linear response theory, we derive the dissipative torque produced by the s-d exchange interaction at the ferromagnet-normal metal interface. For a slow precession, the enhancement of Gilbert damping constant is proportional to the square of the s-d exchange constant times the zero-frequency limit of the frequency derivative of the local dynamic spin susceptibility of the normal metal at the interface. Electron-electron interactions increase the relaxation rate by the Stoner factor squared. We attribute the large anisotropic enhancements of the relaxation rate observed recently in multilayers containing palladium to this mechanism. For free electrons, the present theory compares favorably with recent spin-pumping result of Tserkovnyak et al. [Phys. Rev. Lett. \textbf{88},117601 (2002)].Comment: 1 figure, 5page

Revista de Vertebrados de la Estación Biológica de Doñana

Identification des poils des mammiferes pyreneens.Biología de caza en Falco naumannEtograma del Ciervo (Cervus elaphus) en período de no reproducciónBiología del estornino negro (Sturnus unicolor). II. Dieta del polloObservaciones sobre la actividad nocturna de reptiles en la España mediterránea occidental.Nuevo dato de herpetofagia en Tarentola mauritanicaObservación de Hieratus fasciatus en una corriente migratoria otoñal de rapaces en CeutaObservación invernal de Clamator glandarius en el valle del GuadalquivirUn dato sobre el paso del estrecho de Gibraltar por Gips fulvusDos citas de invernada de Hieräetus pennatus en el valle del GuadalquivirObservación de Sylvia nisoria en el sur de EspañaObservación de Sylvia nisoria en el sur de EspañaNoticia del hallazgo de Baleaphryne (Amphibia: anura Disoglissae) viviente en MallorcaPeer reviewe