The Effect Of Metabolic Syndrome On Comorbidities In Patients With COPD

International Conference of the American-Thoracic-Society (ATS) -- MAY 15-20, 2015 -- Denver, COWOS: 000377582807562…Amer Thorac So

Plasma homocysteine level and 677C -> T mutation on the MTHFR gene in patients with venous thromboembolism

WOS: 000275575500003PubMed ID: 20429317Background: The aim of this study was to evaluate the role of plasma total homocysteine level and 677C -> T mutation on the methylene tetrahydrofolate reductase (MTHFR) gene in the development of venous thromboembolism. Methods: Thirty-six (18 male, 18 female and mean+SD; 48.3 +/- 15.5 years) patients with venous thromboembolism and 25 healthy adults (13 male, 12 female and mean SD; 46.8 +/- 9.2 years) were included in the study. Fasting plasma total homocysteine level was determined by a high performance liquid chromatography. 677C -> T mutation on the MTHFR gene in peripheral blood was detected by Real Time-PCR method. Results: The level of plasma total homocysteine (18.5 +/- 10.6 mu mol/L) was significantly higher in patients with venous thromboembolism than in the control group (11.0 +/- 4.7 mu mol/L) (p=0.015). 677C -> T mutation on the MTHFR gene heterozygosity was higher in the patient group than in the control group [13 (36.1%) and 2 (8%) respectively] but this difference was not significant (p=0.07). Conclusion: It is thought that a high plasma total homocysteine may cause venous thromboembolism (Tab. 2, Ref. 21). Full Text (Free, PDF) www.bmj.sk

Plasma homocysteine level and 677C›T mutation on the MTHFR gene in patients with venous thromboembolism

PubMedID: 20429317Background: The aim of this study was to evaluate the role of plasma total homocysteine level and 677C›T mutation on the methylenetetrahydrofolate reductase (MTHFR) gene in the development of venous thromboembolism. Methods: Thirty-six (18 male, 18 female and mean+SD; 48.3±15.5 years) patients with venous thromboembolism and 25 healthy adults (13 male, 12 female and mean±SD; 46.8±9.2 years) were included in the study. Fasting plasma total homocysteine level was determined by a high performance liquid chromatography. 677C›T mutation on the MTHFR gene in peripheral blood was detected by Real Time-PCR method. Results: The level of plasma total homocysteine (18.5±10.6 umol/L) was significantly higher in patients with venous thromboembolism than in the control group (11.0±4.7 umol/L) (p=0.015). 677C›T mutation on the MTHFR gene heterozygosity was higher in the patient group than in the control group [13 (36.1 %) and 2 (8%) respectively] but this difference was not significant (p=0.07). Conclusion: It is thought that a high plasma total homocysteine may cause venous thromboembolism (Tab. 2, Ref. 21). Full Text (Free, PDF) www.bmj.sk

The efficacy of inhaled hypertonic saline in children with cystic fibrosis who receive daily DNase.

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Rating versus Ranking: What is the Best Way to Reduce Response and Language Bias in Cross-national Research?

Contains fulltext : 125282.pdf (publisher's version ) (Closed access)16 p

Standardization and contextualization: A study of language and leadership across 17 countries

Contains fulltext : 125279.pdf (publisher's version ) (Closed access) Contains fulltext : 125279-Corrigendum.pdf (publisher's version ) (Closed access)9 p