975 research outputs found
Breakdown of `phase rigidity' and variations of the Fano effect in closed Aharonov-Bohm interferometers
Although the conductance of a closed Aharonov-Bohm interferometer, with a
quantum dot on one branch, obeys the Onsager symmetry under magnetic field
reversal, it needs not be a periodic function of this field: the conductance
maxima move with both the field and the gate voltage on the dot, in an apparent
breakdown of `phase rigidity'. These experimental findings are explained
theoretically as resulting from multiple electronic paths around the
interferometer ring. Data containing several Coulomb blockade peaks, whose
shapes change with the magnetic flux, are fitted to a simple model, in which
each resonant level on the dot couples to a different path around the ring
Spin filtering by a periodic nanospintronic devices
For a linear chain of diamond-like elements, we show that the Rashba
spin-orbit interaction (which can be tuned by a perpendicular gate voltage) and
the Aharonov-Bohm flux (due to a perpendicular magnetic field) can combine to
select only one propagating ballistic mode, for which the electronic spins are
fully polarized along a direction that can be tuned by the electric and
magnetic fields and by the electron energy. All the other modes are evanescent.
For a wide range of parameters, this chain can serve as a spin filter.Comment: Published versio
Observation of "Partial Coherence" in an Aharonov-Bohm Interferometer with a Quantum Dot
We report experiments on the interference through spin states of electrons in
a quantum dot (QD) embedded in an Aharonov-Bohm (AB) interferometer. We have
picked up a spin-pair state, for which the environmental conditions are ideally
similar and have traced the AB amplitude in the range of the gate voltage that
covers the pair. The behavior of the asymmetry in the amplitude around the two
Coulomb peaks agrees with the theoretical prediction that relates a spin-flip
process in a QD to the quantum dephasing of electrons. These results consist
evidence of "partial coherence" due to an entanglement of spins in the QD and
the interferometer.Comment: 4 pages, 3 figures, RevTe
Anomalous In-Plane Anisotropy of the Onset of Superconductivity in (TMTSF)2ClO4
We report the magnetic field-amplitude and field-angle dependence of the
superconducting onset temperature Tc_onset of the organic superconductor
(TMTSF)2ClO4 in magnetic fields H accurately aligned to the conductive ab'
plane. We revealed that the rapid increase of the onset fields at low
temperatures occurs both for H // b' and H // a, irrespective of the carrier
confinement. Moreover, in the vicinity of the Pauli limiting field, we report a
shift of a principal axis of the in-plane field-angle dependence of Tc_onset
away from the b' axis. This feature may be related to an occurrence of
Fulde-Ferrell-Larkin-Ovchinnikov phases.Comment: 4 pages, 4 figure
TableHop: an actuated fabric display using transparent electrodes
We present TableHop, a tabletop display that provides controlled self-actuated deformation and vibro-tactile feedback to an elastic fabric surface while retaining the ability for high-resolution visual projection. The TableHop surface is made of a highly stretchable pure spandex fabric that is electrostatically actuated using electrodes mounted on its underside. We use transparent indium tin oxide electrodes and high-voltage modulation to create controlled surface deformations. This setup actuates pixels and creates deformations in the fabric up to 5mm. Since the electrodes are transparent, the fabric surface can function as a diffuser for rear-projected visual images, and avoid occlusion by users. Users can touch and interact with the fabric to create expressive interactions as with any fabric based shape-changing interface. By using frequency modulation in the high-voltage circuit, we can also create localised tactile sensations on the user's finger-tip when touching the surface. We provide detailed simulation results of the shape of the surface deformation and the frequency of the haptic vibrations. These results can be used to build prototypes of different sizes and form-factors. We finally create a working prototype of TableHop that has 3040 cm surface area and uses a grid of 33 transparent electrodes. Our prototype uses a maximum of 2.2 mW and can create tactile vibrations of up to 20 . TableHop can be scaled to large interactive surfaces and integrated with other objects and devices. TableHop will improve user interaction experience on 2.5D deformable displays
Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer.
Expression of the oncogenic transcription factor MYC is disproportionately elevated in triple-negative breast cancer (TNBC), as compared to estrogen receptor-, progesterone receptor- or human epidermal growth factor 2 receptor-positive (RP) breast cancer. We and others have shown that MYC alters metabolism during tumorigenesis. However, the role of MYC in TNBC metabolism remains mostly unexplored. We hypothesized that MYC-dependent metabolic dysregulation is essential for the growth of MYC-overexpressing TNBC cells and may identify new therapeutic targets for this clinically challenging subset of breast cancer. Using a targeted metabolomics approach, we identified fatty acid oxidation (FAO) intermediates as being dramatically upregulated in a MYC-driven model of TNBC. We also identified a lipid metabolism gene signature in patients with TNBC that were identified from The Cancer Genome Atlas database and from multiple other clinical data sets, implicating FAO as a dysregulated pathway that is critical for TNBC cell metabolism. We found that pharmacologic inhibition of FAO catastrophically decreased energy metabolism in MYC-overexpressing TNBC cells and blocked tumor growth in a MYC-driven transgenic TNBC model and in a MYC-overexpressing TNBC patient-derived xenograft. These findings demonstrate that MYC-overexpressing TNBC shows an increased bioenergetic reliance on FAO and identify the inhibition of FAO as a potential therapeutic strategy for this subset of breast cancer
The Nuclear Activity of the Galaxies in the Hickson Compact Groups
In order to investigate the nuclear activity of galaxies residing in compact
groups of galaxies, we present results of our optical spectroscopic program
made at Okayama Astrophysical Observatory. We have performed optical
spectroscopy of 69 galaxies which belong to 31 Hickson Compact Groups (HCGs) of
Galaxies. Among them, three galaxies have discordant redshifts. Further,
spectral quality is too poor to classify other three galaxies. Therefore, we
describe our results for the remaining 63 galaxies.
Our main results are summarized below. (1) We have found in our sample; 28
AGN, 16 HII nuclei, and 19 normal galaxies which show no emission line. We used
this HCG sample for statistical analyses. (2) Comparing the frequency
distributions of activity types between the HCGs and the field galaxies whose
data are taken from Ho, Filippenko, & Sargent (382 field galaxies), we find
that the frequency of HII nuclei in the HCGs is significantly less than that in
the field. However, this difference may be due to selection bias that our HCG
sample contains more early-type galaxies than the field, because it is known
that HII nuclei are rarer in early-type galaxies than in later ones. (3)
Applying correction this morphological bias to the HCG sample, we find that
there is no statistically significant difference in the frequency of occurrence
of emission-line galaxies between the HCGs and the field. This implies that the
dense galaxy environment in the HCGs does not affect triggering both the AGN
activity and the nuclear starburst. We discuss some implications on the nuclear
activity in the HCG galaxies.Comment: 33 pages (3 aasms4 LaTeX files), 5 figures (5 Postscript files:
excluded Figure 1), Accepted for publication in The Astronomical Journa
K3 surfaces and log del Pezzo surfaces of index three
We use classification of non-symplectic automorphisms of K3 surfaces to
obtain a partial classification of log del Pezzo surfaces of index three. We
can classify those with "Multiple Smooth Divisor Property", whose definition we
will give. Our methods include the definition of right resolutions of quotient
singularities of index three and some analysis of automorphism-stable elliptic
fibrations on K3 surfaces. In particular we find several log del Pezzo surfaces
of Picard number one with non-toric singularities of index three.Comment: 32 pages, to appear in Manuscripta Mat
Product Differentiation Costs and Global Competition
The growing competitive intensity on the markets determines the emergence of
competition costs that are expressed at a corporate level and have implicit
repercussions for the supply system. This type of costs makes it possible to identify
a close link between competition costs and supply differentiation costs.
Classification by competitive intensity presupposes that the analysis performed
identifies the classification of company costs as the discriminating element, in
terms of the competitive pressure of the context in which the firm operates.
The emergence of competition costs is linked to an attempt to squeeze them as an
aspect of vertical, or more specifically, horizontal cooperation strategies.Product Differentiation; Differentiation Costs; Over-Supply; Global Competition; Marketing; Market-Driven Management; Global Corporations; Global Markets DOI:http://dx.doi.org/10.4468/2005.1.06garbelli
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