Tsirelson's Bound Prohibits Communication Through a Disconnected Channel

Why does nature only allow nonlocal correlations up to Tsirelson's bound and not beyond? We construct a channel whose input is statistically independent of its output, but through which communication is nevertheless possible if and only if Tsirelson's bound is violated. This provides a statistical justification for Tsirelson's bound on nonlocal correlations in a bipartite setting.Comment: 9 pages, 2 figures. Title and abstract modified, exposition simplifie

Low-Dimensional Topology of Information Fusion

We provide an axiomatic characterization of information fusion, on the basis of which we define an information fusion network. Our construction is reminiscent of tangle diagrams in low dimensional topology. Information fusion networks come equipped with a natural notion of equivalence. Equivalent networks `contain the same information', but differ locally. When fusing streams of information, an information fusion network may adaptively optimize itself inside its equivalence class. This provides a fault tolerance mechanism for such networks.Comment: 8 pages. Conference proceedings version. Will be superceded by a journal versio

Computing with Coloured Tangles

We suggest a diagrammatic model of computation based on an axiom of distributivity. A diagram of a decorated coloured tangle, similar to those that appear in low dimensional topology, plays the role of a circuit diagram. Equivalent diagrams represent bisimilar computations. We prove that our model of computation is Turing complete, and that with bounded resources it can moreover decide any language in complexity class IP, sometimes with better performance parameters than corresponding classical protocols.Comment: 36 pages,; Introduction entirely rewritten, Section 4.3 adde

Managing women in pregnancy after bariatric surgery: The midwife as the co-ordinator of care

Bariatric surgery is a recommended, cost-effective, evidenced-based intervention to reduce weight and associated comorbidities in severely obese people. People with a BMI of 40 kg/m2 or more, or a BMI between 35–40 kg/m2 with other medical conditions such as diabetes, hypertension, high cholesterol and obstructive sleep apnoea meet the criteria to be considered for bariatric surgery. Over the past 10 years, bariatric surgery in the UK has been more widely accessible and consequently midwives may be required to care for pregnant women who have undergone bariatric surgery such as a gastric band, sleeve gastrectomy and gastric bypass. Midwives are required to work co-operatively, recognising and working within the limits of their competence and providing leadership. The aim of this article is to consider the midwife's role as co-ordinator of care for pregnant women who have undergone bariatric surgery. It outlines the most common bariatric procedures and specific considerations, including nutritional supplementation required when providing care to women in the antenatal and postnatal period

Photonic quantum information processing: a review

Photonic quantum technologies represent a promising platform for several applications, ranging from long-distance communications to the simulation of complex phenomena. Indeed, the advantages offered by single photons do make them the candidate of choice for carrying quantum information in a broad variety of areas with a versatile approach. Furthermore, recent technological advances are now enabling first concrete applications of photonic quantum information processing. The goal of this manuscript is to provide the reader with a comprehensive review of the state of the art in this active field, with a due balance between theoretical, experimental and technological results. When more convenient, we will present significant achievements in tables or in schematic figures, in order to convey a global perspective of the several horizons that fall under the name of photonic quantum information.Comment: 36 pages, 6 figures, 634 references. Updated version with minor changes and extended bibliograph

CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers

The membrane attack complex (MAC) is one of the immune system’s first responders. Complement proteins assemble on target membranes to form pores that lyse pathogens and impact tissue homeostasis of self-cells. How MAC disrupts the membrane barrier remains unclear. Here we use electron cryo-microscopy and flicker spectroscopy to show that MAC interacts with lipid bilayers in two distinct ways. Whereas C6 and C7 associate with the outer leaflet and reduce the energy for membrane bending, C8 and C9 traverse the bilayer increasing membrane rigidity. CryoEM reconstructions reveal plasticity of the MAC pore and demonstrate how C5b6 acts as a platform, directing assembly of a giant β-barrel whose structure is supported by a glycan scaffold. Our work provides a structural basis for understanding how β-pore forming proteins breach the membrane and reveals a mechanism for how MAC kills pathogens and regulates cell functions