Data processing system for the Sneg-2MP experiment

The data processing system for scientific experiments on stations of the "Prognoz" type provides for the processing sequence to be broken down into a number of consecutive stages: preliminary processing, primary processing, secondary processing. The tasks of each data processing stage are examined for an experiment designed to study gamma flashes of galactic origin and solar flares lasting from several minutes to seconds in the 20 kev to 1000 kev energy range

COVID-19 pandemic as a socio-psychological influence on transformations in religion

This article aims to establish COVID-19’s sociopsychological influence on religion. This interdisciplinary study’s theoretical framework embraces the socialecological systems framework, the concept of deprivation, the theory of religious myth-making, religious individualism and bricolage, as well as the concept of quality of life. A sociological survey was conducted of 4,700 residents of Moscow and the Moscow region. The results revealed that the social sphere of society was relatively stable duringthe pandemic. Exploring COVID-19’s socio-psychological influence, this study examines transformations in religion that resulted from tactile deprivation.&nbsp

Phase equilibria, crystal structure and oxygen content of intermediate phases in the Y-Ba-Co-O system

The phase equilibria in the Y-Ba-Co-O system were systematically studied at 1373 K in air. The intermediate phases formed in the Y-Ba-Co-O system at 1373 K in air were: YBaCo2O5+δ, YBaCo4O 7 and BaCo1-yYyO3-δ (0.09≤y≤0.42). It was shown that YBaCo2O5+δ possesses tetragonal structure with the 3ap×3a p×2ap superstructure (sp. gr. P4/mmm). High-temperature X-ray diffraction analysis of the YBaCo2O 5+δ in the temperature range from 298 K up to 1073 K under Po2=0.21 atm has not shown any phase transformations. The value of oxygen content for the YBaCo2O5+δ at room temperature was estimated as 5.40 and at 1323 K it was equal to 5.04. Thermal expansion of sample shows a linear characteristics and the average thermal expansion coefficient (TEC) is about 13.8×10-6, K-1 in the temperature range 298-1273 K. The homogeneity range and crystal structure of the BaCo1-yYyO3-δ (0.09≤y≤0.42) solid solutions were determined by X-ray diffraction of quenched samples. All BaCo1-yYyO3-δ solid solutions were found to have cubic structure (sp. gr. Pm3m). The unit cell parameters were refined using Rietveld full-profile analysis. Oxygen nonstoichiometry of BaCo 1-yYyO3-δ solid solutions with 0.1≤y≤0.4 was measured by means of thermogravimetric technique within the temperature range 298-1373 K in air. Thermal expansion of BaCo 1-yYyO3-δ (y=0.0; 0.1; 0.2; 0.3) samples was studied within the temperature range 298-1200 K in air. The projection of isothermal-isobaric phase diagram for the Y-Ba-Co-O system to the compositional triangle of metallic components was presented. © 2013 Elsevier Inc

Comparative assessment of physicians’ and senior medical students’ basic knowledge in treatment of chronic obstructive pulmonary disease

The article represents the results of anonymous prospective survey within the ASCO project (full title - "Assessment of Senior Medical Students in the Field of COPD"), aimed at assessing the basic knowledge in the COPD treatmen

Vibrational and magnetic properties of crystalline CuTe2O5

© 2014, Pleiades Publishing, Inc. In the present work we have performed an ab initio calculation of vibrational properties of CuTe2O5 by means of density functional theory (DFT) method. One has compared calculated values with known experimental data on Raman and infrared spectroscopy in order to verify the obtained results. Lattice contribution to the heat capacity obtained from the ab initio simulations was added to magnetic contribution calculated from the simple spin Hamiltonian model in order to obtain total heat capacity. Obtained results are in good agreement with the experimental data. Thus, the DFT methods could complement the experimental and theoretical studying of low-dimensional magnetic systems such as CuTe2O5

The assessment of physicians' and senior medical students’ knowledge in the field of community-acquired pneumonia: preliminary results of the KNOCAP-II project (2017-2019)

The aim of the study is to assess the level of general physician’ and senior medical students’ basic knowledge in CAP treatment. The article represents the results of anonymous prospective surveys within the framework of the second stage of KNOCAP multi-centered research project (full name of the project "The assessment of physician’ and students’ knowledge of community-acquired pneumonia basics") aimed at accessing the knowledge and preferences of doctors and students on the fundamental issues in diagnosis and treatment of community-acquired pneumoni

Pharmacotherapy and other aspects of senior medical students’ knowledge in community-acquired pneumonia: the final results of the KNOCAP II project

To determine the level of senior medical students’ basic knowledge of CAP prevention, diagnosis and treatment with the help of a pharmacoepidemiological stud

Modern approaches to pharmacotherapy of community-acquired pneumonia

The study presents current views on the pharmacotherapy of community-acquired pneumonia (CAP). This study also describes in general terms the current pharmacoepidemiological situation of the CAP in Russia and abroad, which can both help medical professionals make an informed choice when choosing a pharmacotherapy, and inspire them to follow-up research and observation

Activation of Human Stearoyl-Coenzyme A Desaturase 1 Contributes to the Lipogenic Effect of PXR in HepG2 Cells

The pregnane X receptor (PXR) was previously known as a xenobiotic receptor. Several recent studies suggested that PXR also played an important role in lipid homeostasis but the underlying mechanism remains to be clearly defined. In this study, we found that rifampicin, an agonist of human PXR, induced lipid accumulation in HepG2 cells. Lipid analysis showed the total cholesterol level increased. However, the free cholesterol and triglyceride levels were not changed. Treatment of HepG2 cells with rifampicin induced the expression of the free fatty acid transporter CD36 and ABCG1, as well as several lipogenic enzymes, including stearoyl-CoA desaturase-1 (SCD1), long chain free fatty acid elongase (FAE), and lecithin-cholesterol acyltransferase (LCAT), while the expression of acyl:cholesterol acetyltransferase(ACAT1) was not affected. Moreover, in PXR over-expressing HepG2 cells (HepG2-PXR), the SCD1 expression was significantly higher than in HepG2-Vector cells, even in the absence of rifampicin. Down-regulation of PXR by shRNA abolished the rifampicin-induced SCD1 gene expression in HepG2 cells. Promoter analysis showed that the human SCD1 gene promoter is activated by PXR and a novel DR-7 type PXR response element (PXRE) response element was located at -338 bp of the SCD1 gene promoter. Taken together, these results indicated that PXR activation promoted lipid synthesis in HepG2 cells and SCD1 is a novel PXR target gene. © 2013 Zhang et al