680 research outputs found

    Design and Characterization for Regenerative Shock Absorbers

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    L'abstract è presente nell'allegato / the abstract is in the attachmen

    A Robust Data-driven Process Modeling Applied to Time-series Stochastic Power Flow

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    In this paper, we propose a robust data-driven process model whose hyperparameters are robustly estimated using the Schweppe-type generalized maximum likelihood estimator. The proposed model is trained on recorded time-series data of voltage phasors and power injections to perform a time-series stochastic power flow calculation. Power system data are often corrupted with outliers caused by large errors, fault conditions, power outages, and extreme weather, to name a few. The proposed model downweights vertical outliers and bad leverage points in the measurements of the training dataset. The weights used to bound the influence of the outliers are calculated using projection statistics, which are a robust version of Mahalanobis distances of the time series data points. The proposed method is demonstrated on the IEEE 33-Bus power distribution system and a real-world unbalanced 240-bus power distribution system heavily integrated with renewable energy sources. Our simulation results show that the proposed robust model can handle up to 25% of outliers in the training data set.Comment: Submitted to the IEEE Transactions on Power System

    IPO7 promotes pancreatic cancer progression via regulating ERBB pathway

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    Background: Importin 7 (IPO7) belongs to the Importin β family and is implicated in the progression of diverse human malignancies. This work is performed to probe the role of IPO7 in pancreatic cancer development and its potential downstream mechanisms. Methods: IPO7 expression in PC and paracancerous tissues were measured using Immunohistochemistry (IHC) staining and qRT-PCR. Western blotting was utilized to detect the expression level of IPO7 in PC cells and immortalize the pancreatic ductal epithelial cell line. After constructing the IPO7 overexpression and knockdown models, the effect of IPO7 on the proliferation of PC cells was analyzed by the CCK-8 and EdU assay. The migration and invasion of PC cells were examined by wound healing assay and Transwell experiment. The apoptosis rate of PC cells was analyzed by flow cytometry and TUNEL assay. The Gene Set Enrichment Analysis (GSEA) was used to determine the enrichment pathways of IPO7. The effect of IPO7 on the ERBB2 expression was determined using Western blotting. A xenograft mouse model was applied to investigate the carcinogenic effect of IPO7 in vivo. Results: IPO7 expression was remarkably elevated in the cancer tissues of PC patients. IPO7 overexpression remarkably enhanced PC cell proliferation, migration and invasion and suppressed apoptosis, while knockdown of IPO7 exerted the opposite effect. Mechanistically, IPO7 facilitated the malignant phenotype of PC cells by up-regulating ERBB2 expression. In addition, knockdown of IPO7 inhibited tumor growth and lung metastasis in vivo. Conclusion: IPO7 can act as an oncogenic factor and accelerate PC progression by modulating the ERBB pathway

    An Efficient Multifidelity Model for Assessing Risk Probabilities in Power Systems under Rare Events

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    Risk assessment of power system failures induced by low-frequency, high-impact rare events is of paramount importance to power system planners and operators. In this paper, we develop a cost-effective multi-surrogate method based on multifidelity model for assessing risks in probabilistic power-flow analysis under rare events. Specifically, multiple polynomial-chaos-expansion-based surrogate models are constructed to reproduce power system responses to the stochastic changes of the load and the random occurrence of component outages. These surrogates then propagate a large number of samples at negligible computation cost and thus efficiently screen out the samples associated with high-risk rare events. The results generated by the surrogates, however, may be biased for the samples located in the low-probability tail regions that are critical to power system risk assessment. To resolve this issue, the original high-fidelity power system model is adopted to fine-tune the estimation results of low-fidelity surrogates by reevaluating only a small portion of the samples. This multifidelity model approach greatly improves the computational efficiency of the traditional Monte Carlo method used in computing the risk-event probabilities under rare events without sacrificing computational accuracy

    Photoelectrochemical Reduction of CO2 over Graphene-Based Composites: Basic Principle, Recent Progress, and Future Perspective

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    面对日益严重的化石能源消耗和温室效应问题,二氧化碳还原正成为一个重要的全球性研究课题,其通过消耗二氧化碳来生成可用于能源供应的产物。光电催化技术; 同时利用光能和外部电压,是一种用于二氧化碳还原的可行且有效的途径。因为石墨烯具有增强二氧化碳吸附和促进光生电子转移的特性能够提升石墨烯基复合电极; 的性能,所以引入石墨烯用于调优光电催化二氧化碳还原体系已经引起了广泛关注。本篇综述详细陈述了石墨烯基复合材料应用于光电二氧化碳还原的基本原理,电; 极制备方法以及目前的研究进展。我们也对这个蓬勃发展的领域未来可能会遇到的机遇和挑战进行了展望,同时提出了潜在可行的革新策略用于提升光电二氧化碳还; 原方面的研究。In response to aggravated fossil resources consuming and greenhouse effect, CO2 reduction has become a globally important scientific issue because this method can be used to produce value-added feedstock for application in alternative energy supply. Photoelectrocatalysis, achieved by combining optical energy and external electrical bias, is a feasible and promising system for CO2 reduction. In particular, applying graphene in tuning photoelectrochemical CO2 reduction has aroused considerable attention because graphene is advantageous for enhancing CO2 adsorption, facilitating electrons transfer, and thus optimizing the performance of graphene-based composite electrodes. In this review, we elaborate the fundamental principle, basic preparation methods, and recent progress in developing a variety of graphene-based composite electrodes for photoelectrochemical reduction of CO2 into solar fuels and chemicals. We also present a perspective on the opportunities and challenges for future research in this booming area and highlight the potential evolution strategies for advancing the research on photoelectrochemical CO2 reduction.National Natural Science Foundation of China [U1463204, 20903023,; 21173045]; Award Program for Minjiang Scholar Professorship; Natural; Science Foundation of Fujian Province [2012J06003, 2017J07002];; Independent Research Project of State Key Laboratory of Photocatalysis; on Energy and Environment [2014A05]; first Program of Fujian Province; for Top Creative Young Talents; Open Research Project of State Key; Laboratory of Physical Chemistry of Solid Surfaces of Xiamen University; [201519]; Program for Returned High-Level Overseas Chinese Scholars of; Fujian provinc

    Rethink left-behind experience: new categories and its relationship with aggression

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    Left-behind experience refers to the experience of children staying behind in their hometown under the care of only one parent or their relatives while one or both of their parents leave to work in other places. College students with left-behind experience showed higher aggression levels. To further explore the relationship between left-behind experience and aggression, the current study categorized left-behind experience using latent class analysis and explored its relationship with aggression. One thousand twenty-eight Chinese college students with left-behind experience were recruited, and their aggression levels were assessed. The results showed that there were four categories of left-behind experience: “starting from preschool, frequent contact” (35.5%), “less than 10 years in duration, limited contact” (27.0%), “starting from preschool, over 10 years in duration, limited contact” (10.9%), and “starting from school age, frequent contact” (26.6%). Overall, college students who reported frequent contact with their parents during the left-behind period showed lower levels of aggression than others did. Females were less aggressive than males in the “starting from preschool, frequent contact” left-behind situation, while males were less aggressive than females in the “starting from school age, frequent contact” situation. These findings indicate that frequent contact with leaving parents contributes to decreasing aggression of college students with left-behind experience. Meanwhile, gender is an important factor in this relationship
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