Is f1(1420)f_1(1420) the partner of f1(1285)f_1(1285) in the 3P1^3P_1 qqˉq\bar{q} nonet?

Based on a $2\times 2$ mass matrix, the mixing angle of the axial vector states $f_1(1420)$ and $f_1(1285)$ is determined to be $51.5^{\circ}$, and the theoretical results about the decay and production of the two states are presented. The theoretical results are in good agreement with the present experimental results, which suggests that $f_1(1420)$ can be assigned as the partner of $f_1(1285)$ in the $^3P_1$ $q\bar{q}$ nonet. We also suggest that the existence of $f_1(1510)$ needs further experimental confirmation.Comment: Latex, 6 pages, to be published in Chin. Phys. let

Distinct Requirements for Extracellular and Intracellular MMP12 in the Development of the Adult V-SVZ Neural Stem Cell Niche

Summary: The regulatory mechanisms that control neural stem cell (NSC) activation in the adult ventricular-subventricular zone (V-SVZ) stem cell niche have been the focus of intense investigation, yet how the niche first develops and organizes is poorly understood. Here, we examined matrix metalloproteinases (MMPs) for potential roles in V-SVZ stem cell niche development. MMP12 was found to promote appropriate niche cellular arrangements, the formation of specialized niche extracellular matrix, and the translational planar cell polarity of ependymal cells that surround and support niche NSCs. Surprisingly, ependymal cells were found to have an intracellular pool of MMP12 that promoted ependymal cell ciliogenesis by upregulating FOXJ1. In addition, both extracellular and intracellular MMP12 were found to regulate V-SVZ niche output by promoting NSC quiescence. These findings reveal that extracellular and intracellular MMP12 have both unique and overlapping roles that help orchestrate the development of the adult V-SVZ stem cell niche. : Shan et al. report that matrix metalloproteinase 12 (MMP12) is required for the appropriate development of the V-SVZ neural stem cell niche, with secreted MMP12 promoting niche organization and function, including the regulation of neural stem cell quiescence. An unexpected intracellular pool of a truncated yet functional MMP12 was also identified, which has a distinct role in promoting ependymal ciliogenesis. Keywords: neural stem cell niche, ependymal cell, matrix metalloproteinase, ventricular-subventricular zone, V-SV

Semi-Supervised Multi-View Correlation Feature Learning with Application to Webpage Classification

Webpage classification has attracted a lot of research interest. Webpage data is often multi-view and high-dimensional, and the webpage classification application is usually semi-supervised. Due to these characteristics, using semi-supervised multi-view feature learning (SMFL) technique to deal with the webpage classification problem has recently received much attention. However, there still exists room for improvement for this kind of feature learning technique. How to effectively utilize the correlation information among multi-view of webpage data is an important research topic. Correlation analysis on multi-view data can facilitate extraction of the complementary information. In this paper, we propose a novel SMFL approach, named semi-supervised multi-view correlation feature learning (SMCFL), for webpage classification. SMCFL seeks for a discriminant common space by learning a multi-view shared transformation in a semi-supervised manner. In the discriminant space, the correlation between intra-class samples is maximized, and the correlation between inter-class samples and the global correlation among both labeled and unlabeled samples are minimized simultaneously. We transform the matrix-variable based nonconvex objective function of SMCFL into a convex quadratic programming problem with one real variable, and can achieve a global optimal solution. Experiments on widely used datasets demonstrate the effectiveness and efficiency of the proposed approach

MeCP2 is critical for maintaining mature neuronal networks and global brain anatomy during late stages of postnatal brain development and in the mature adult brain

Mutations in the X-linked gene, methyl-CpG binding protein 2 (Mecp2), underlie a wide range of neuropsychiatric disorders, most commonly, Rett Syndrome (RTT), a severe autism spectrum disorder that affects approximately one in 10,000 female live births. Because mutations in the Mecp2 gene occur in the germ cells with onset of neurological symptoms occurring in early childhood, the role of MeCP2 has been ascribed to brain maturation at a specific developmental window. Here, we show similar kinetics of onset and progression of RTT-like symptoms in mice, including lethality, if MeCP2 is removed postnatally during the developmental stage that coincides with RTT onset, or adult stage. For the first time, we show that brains that lose MeCP2 at these two different stages are actively shrinking, resulting in higher than normal neuronal cell density. Furthermore, we show that mature dendritic arbors of pyramidal neurons are severely retracted and dendritic spine density is dramatically reduced. In addition, hippocampal astrocytes have significantly less complex ramified processes. These changes accompany a striking reduction in the levels of several synaptic proteins, including CaMKII α/β, AMPA, and NMDA receptors, and the synaptic vesicle proteins Vglut and Synapsin, which represent critical modifiers of synaptic function and dendritic arbor structure. Importantly, the mRNA levels of these synaptic proteins remains unchanged, suggesting that MeCP2 likely regulates these synaptic proteins post-transcriptionally, directly or indirectly. Our data suggest a crucial role for MeCP2 in post-transcriptional regulation of critical synaptic proteins involved in maintaining mature neuronal networks during late stages of postnatal brain development. © 2012 the authors

Research data supporting "Structurally Colored Radiative Cooling Cellulosic Films"

Electronic supporting Information is available from the publisher (Advanced Science). The data is provided within a structured set of folders compressed in zip, each correlating to a specific figure in the article. Spreadsheets are provided as ‘.xlsx’ or '.txt'; images as ‘.bmp’, ‘.jpeg’, ‘.tiff’ or ‘.png’. The data include photograph and the results of polarized optical microscopy, UV-VIS spectroscopy, FTIR spectroscopy, goniometer measurement, field test, and SEM. The methods part of the published paper has the detailed description of how the data were generated, collected, and processed.Startup Funds from School of Mechanical Engineering at Purdue University, ASME Haythornthwaite Foundation Research Initiation Grant, and the Shanghai Jiao Tong Grant

Universal Color Retrofit to Polymer-Based Radiative Cooling Materials

Polymers with broad infrared emission and negligible solar absorption have been identified as promising radiative cooling materials to offer a sustainable and energy-saving venue. Although practical applications desire color for visual appearance, the current coloration strategies of polymer-based radiative cooling materials are constrained by material, cost, and scalability. Here, we demonstrate a universally applicable coloration strategy for polymer-based radiative cooling materials by nanoimprinting. By modulating light interference with periodic structures on polymer surfaces, specular colors can be induced while maintaining the hemispheric optical responses of radiative cooling polymers. The retrofit strategy is exemplified by four different polymer films with a minimum impact on optical responses compared to the pristine films. Polymer films feature low solar absorption of 1.7–3.7%, and daytime sub-ambient cooling is exemplified in the field test. The durability of radiative cooling and color are further validated by dynamic spectral analysis. Finally, the potential roll-to-roll manufacturing empowers a scalable, low-cost, and easy-retrofitting solution for colored radiative cooling films

Structurally Colored Radiative Cooling Cellulosic Films.

Funder: Purdue University; Id: http://dx.doi.org/10.13039/100006377Funder: ASME Haythornthwaite Foundation ResearchFunder: Shanghai Jiao TongDaytime radiative cooling (DRC) materials offer a sustainable approach to thermal management by exploiting net positive heat transfer to deep space. While such materials typically have a white or mirror-like appearance to maximize solar reflection, extending the palette of available colors is required to promote their real-world utilization. However, the incorporation of conventional absorption-based colorants inevitably leads to solar heating, which counteracts any radiative cooling effect. In this work, efficient sub-ambient DRC (Day: -4 °C, Night: -11 °C) from a vibrant, structurally colored film prepared from naturally derived cellulose nanocrystals (CNCs), is instead demonstrated. Arising from the underlying photonic nanostructure, the film selectively reflects visible light resulting in intense, fade-resistant coloration, while maintaining a low solar absorption (≈3%). Additionally, a high emission within the mid-infrared atmospheric window (>90%) allows for significant radiative heat loss. By coating such CNC films onto a highly scattering, porous ethylcellulose (EC) base layer, any sunlight that penetrates the CNC layer is backscattered by the EC layer below, achieving broadband solar reflection and vibrant structural color simultaneously. Finally, scalable manufacturing using a commercially relevant roll-to-roll process validates the potential to produce such colored radiative cooling materials at a large scale from a low-cost and sustainable feedstock.Startup Funds from School of Mechanical Engineering at Purdue University, ASME Haythornthwaite Foundation Research Initiation Grant, the European Research Council (ERC-2014-STG H2020 639088), the Engineering and Physical Sciences Research Council (EPSRC: EP/R511675/1; EP/N016920/1; EP/L015978/1), the Biotechnology and Biological Sciences Research Council (BBSRC: BB/V00364X/1), the European Union Horizon 2020 Marie Skłodowska-Curie research and innovation programme (H2020-MSCA-ITN-2016 722842), the Shanghai Jiao Tong Grant

All-Optical Electrophysiology in hiPSC-Derived Neurons With Synthetic Voltage Sensors

Voltage imaging and “all-optical electrophysiology” in human induced pluripotent stem cell (hiPSC)-derived neurons have opened unprecedented opportunities for high-throughput phenotyping of activity in neurons possessing unique genetic backgrounds of individual patients. While prior all-optical electrophysiology studies relied on genetically encoded voltage indicators, here, we demonstrate an alternative protocol using a synthetic voltage sensor and genetically encoded optogenetic actuator that generate robust and reproducible results. We demonstrate the functionality of this method by measuring spontaneous and evoked activity in three independent hiPSC-derived neuronal cell lines with distinct genetic backgrounds