1,123 research outputs found

    An Exploration of the Characteristic of Small Loan Companies in the Chinese Credit Market

    Get PDF
    Abstract: The small loan company is an emergent novelty for the Chinese credit market. The basic function of it is the financial intermediary which provides important services to some private sectors of the China economy. But as a new-born business, there are no systematic research on it and lack of effective supervision as well. This study investigates the features of financial service constitution, time distribution, risk management and earning capacity of small loan company. The results indicate it will continue to play an important role in China credit-system. Key words: Characteristic; Small loan companies; Chinese credit marke

    Effects of medical consortium policy on health services: an interrupted time-series analysis in Sanming, China

    Get PDF
    ObjectivesChina has implemented reforms to enhance the operational efficiency of three-level medical services through medical consortiums (MCs). This study evaluated the impact of MCs reform on health services in Sanming, China.MethodsAn interrupted time-series analysis (ITSA) was conducted to assess the impact of MCs on changes in health service levels and trends across the overall situation of MCs and different institutional types within MCs, including county hospitals and grassroots medical institutions. The evaluation focused on various indicators such as outpatient and emergency visits, inpatients, average length of stay, occupancy rate of hospital beds, and hospital bed turnover times. Monthly data were collected from April 2015 to June 2019 through reports on the Sanming Municipal Health Commission website and the Sanming public hospital management monitoring platform.ResultsAfter the intervention of MCs reform, a significant increase was observed in the total number of inpatients (β3 = 174.28, p < 0.05). However, no statistically significant change was observed in the total number of outpatient and emergency visits (β3 = 155.82, p = 0.91). Additionally, the implementation of MCs reform led to an amplification in service volumes provided by county hospitals, with significant increases in the number of outpatient and emergency visits (β3 = 1376.54, p < 0.05) and an upward trend in the number of inpatients (β3 = 98.87, p < 0.01). However, no significant changes were observed under the MCs policy for grassroots medical institutions regarding the number of outpatient and emergency visits (β3 = −1220.72, p = 0.22) and number of inpatients (β3 = 75.42, p = 0.09).ConclusionThe Sanming MCs reform has achieved some progress in augmenting service volumes. Nevertheless, it has not led to an increase in service volumes at the grassroots medical institutions. There persists an insufficiency in the efficiency of services and a need for further improvement in primary healthcare. To address these concerns, it is imperative for county hospitals to offer targeted assistance that can enhance motivation among grassroots medical institutions. Besides the MCs should explore initiatives, including improved management of medical equipment, allocation of funding, and personnel resources

    Sim-T: Simplify the Transformer Network by Multiplexing Technique for Speech Recognition

    Full text link
    In recent years, a great deal of attention has been paid to the Transformer network for speech recognition tasks due to its excellent model performance. However, the Transformer network always involves heavy computation and large number of parameters, causing serious deployment problems in devices with limited computation sources or storage memory. In this paper, a new lightweight model called Sim-T has been proposed to expand the generality of the Transformer model. Under the help of the newly developed multiplexing technique, the Sim-T can efficiently compress the model with negligible sacrifice on its performance. To be more precise, the proposed technique includes two parts, that are, module weight multiplexing and attention score multiplexing. Moreover, a novel decoder structure has been proposed to facilitate the attention score multiplexing. Extensive experiments have been conducted to validate the effectiveness of Sim-T. In Aishell-1 dataset, when the proposed Sim-T is 48% parameter less than the baseline Transformer, 0.4% CER improvement can be obtained. Alternatively, 69% parameter reduction can be achieved if the Sim-T gives the same performance as the baseline Transformer. With regard to the HKUST and WSJ eval92 datasets, CER and WER will be improved by 0.3% and 0.2%, respectively, when parameters in Sim-T are 40% less than the baseline Transformer

    Effect of a combination of Tuina therapy and budesonide inhalation on asthma in children, and its influence on lung function and pro inflammatory f actors

    Get PDF
    Purpose: To determine the effect of a combination of Tuina therapy and budesonide inhalation on pediatric asthma, and its influence on lung function and levels of inflammatory factors. Methods: Eligible 100 asthmatic children admitted to Provincial Maternity and Child-care Hospital, Lanzhou, Gansu Province, from January 2019 to January 2021 were randomized either to a control group or study group (1:1). The patients in control group were treated with budesonide inhalation, while the study group was given Tuina therapy in combination with budesonide inhalation. Treatment effectiveness, levels of inflammatory factors, immune functions and number of infections were evaluated in the patients. Results: The study group exhibited higher effectiveness profile versus the control group (96 vs 82 %; p < 0.05). After treatment, decreases were observed in the frequency of asthmatic attacks and number of respiratory infections in the two groups, with lower results in the study group than in the control group (p < 0.05). There were marked decreases in the levels of IgG, TNF-α and IL-8 in both groups, with the study group showing higher reductions (p < 0.05). Conclusion: Combined treatment with Tuina and budesonide inhalation decreases the levels of inflammatory factors, regulates immune function, and improves lung function of asthmatic children. Further investigation in a larger population would be required to establish the mechanism and clinical value of this therapy

    EBF1, PAX5, and MYC: regulation on B cell development and association with hematologic neoplasms

    Get PDF
    During lymphocyte development, a diverse repertoire of lymphocyte antigen receptors is produced to battle against pathogens, which is the basis of adaptive immunity. The diversity of the lymphocyte antigen receptors arises primarily from recombination-activated gene (RAG) protein-mediated V(D)J rearrangement in early lymphocytes. Furthermore, transcription factors (TFs), such as early B cell factor 1 (EBF1), paired box gene 5 (PAX5), and proto-oncogene myelocytomatosis oncogene (MYC), play critical roles in regulating recombination and maintaining normal B cell development. Therefore, the aberrant expression of these TFs may lead to hematologic neoplasms

    Effects of mindfulness and fatigue on emotional processing: an event-related potentials study

    Get PDF
    Fatigue is a common experience in everyday life. People who experience fatigue will have more intense negative emotions, and at the same time, their positive emotions will decrease, impairing the individual’s emotional processing ability. In previous research, mindfulness meditation reduces the intensity of negative emotional stimuli. However, if individuals continue to be affected by negative emotions when they are fatigued, it is unclear whether mindfulness can buffer the negative association between fatigue and emotions. This study examined whether mindfulness meditation affects the association between fatigue and emotions, using event-related potentials (ERPs). One hundred and forty-five participants completed the experiment. They were randomly assigned to the Mindfulness or Non-mindfulness group; and they were presented with positive, neutral, or negative pictures in an emotional processing task before and after mindfulness or rest. Late positive potential (LPP) is an important indicator of emotional stimuli perceived by individuals, and positive or negative pictures can induce an increase in LPP amplitude more than neutral pictures. Our findings suggest that fatigue significantly affected individuals’ LPP amplitudes in the early, mid, and late windows in the Non-mindfulness group, specifically, the more fatigued individuals had lower LPP amplitudes, but not in the Mindfulness group. These results suggest that in a state of fatigue, mindful individuals are able to maintain responsiveness to emotional stimuli by maintaining LPP amplitude. Our study has demonstrated that mindfulness meditation, to some extent, offsets the negative association of fatigue with the neural activation of emotions

    A photo-responsive F-box protein FOF2 regulates floral initiation by promoting FLC expression in Arabidopsis.

    Get PDF
    Floral initiation is regulated by various genetic pathways in response to light, temperature, hormones and developmental status; however, the molecular mechanisms underlying the interactions between different genetic pathways are not fully understood. Here, we show that the photoresponsive gene FOF2 (F-box of flowering 2) negatively regulates flowering. FOF2 encodes a putative F-box protein that interacts specifically with ASK14, and its overexpression results in later flowering under both long-day and short-day photoperiods. Conversely, transgenic plants expressing the F-box domain deletion mutant of FOF2 (FOF2ΔF), or double loss of function mutant of FOF2 and FOL1 (FOF2-LIKE 1) present early flowering phenotypes. The late flowering phenotype of the FOF2 overexpression lines is suppressed by the flc-3 loss-of-function mutation. Furthermore, FOF2 mRNA expression is regulated by autonomous pathway gene FCA, and the repressive effect of FOF2 in flowering can be overcome by vernalization. Interestingly, FOF2 expression is regulated by light. The protein level of FOF2 accumulates in response to light, whereas it is degraded under dark conditions via the 26S proteasome pathway. Our findings suggest a possible mechanistic link between light conditions and the autonomous floral promotion pathway in Arabidopsis

    Review of γ’ Rafting Behavior in Nickel-Based Superalloys: Crystal Plasticity and Phase-Field Simulation

    Get PDF
    Rafting is an important phenomenon of the microstructure evolution in nickel-based single crystal superalloys at elevated temperature. Understanding the rafting mechanism and its effect on the microstructure evolution is of great importance in determining the structural stability and applications of the single crystal superalloys. Phase-field method, which is an excellent tool to analyze the microstructure evolution at mesoscale, has been gradually used to investigate the rafting behavior. In this work, we review the crystal plasticity theory and phase-field method and discuss the application of the crystal plasticity theory and phase-field method in the analysis of the creep deformation and microstructure evolution of the single crystal superalloys
    • …
    corecore