Multiobjective Particle Swarm Optimization Based on PAM and Uniform Design

In MOPSO (multiobjective particle swarm optimization), to maintain or increase the diversity of the swarm and help an algorithm to jump out of the local optimal solution, PAM (Partitioning Around Medoid) clustering algorithm and uniform design are respectively introduced to maintain the diversity of Pareto optimal solutions and the uniformity of the selected Pareto optimal solutions. In this paper, a novel algorithm, the multiobjective particle swarm optimization based on PAM and uniform design, is proposed. The differences between the proposed algorithm and the others lie in that PAM and uniform design are firstly introduced to MOPSO. The experimental results performing on several test problems illustrate that the proposed algorithm is efficient

The formation and stability of junctions in single-wall carbon nanotubes

The structure and stability of molecular junctions, which connect two single-wall carbon nanotubes (SWCNTs) of different diameters and chiral angles, (n(1), m(1))-(n(2), m(2)), are systematically investigated by density functional tight binding calculations. More than 100 junctions, which connect well-aligned SWCNTs, were constructed and calculated. For a highly stable junction between two chiral (n(1), m(1)) and (n(2), m(2)) SWCNTs with opposite handedness, the number of pentagon-heptagon (5/7) pairs required to build the junction can be denoted as vertical bar vertical bar n(2) - n(1)vertical bar - vertical bar m(2) - m(1)vertical bar vertical bar + min{vertical bar n(2) - n(1)vertical bar, vertical bar m(2) - m(1)vertical bar} with (n(2), m(2)) rotating pi/3 angle or not. While for a junction connected by two zigzag, armchair or two chiral SWCNTs with the same handedness, the number of 5/7 pairs is equal to vertical bar n(1) - n(2)vertical bar + vertical bar m(1) - m(2)vertical bar. Similar to the formation energies of grain boundaries in graphene, the curve of the formation energies vs. chiral angle difference present an 'M' shape indicating the preference of similar to 30 degree junctions. Moreover, the formation energies of the zigzag-type and armchair-type junctions with zero misorientation angles are largely sensitive to the diameter difference of two sub-SWCNTs

Flavonoids and its derivatives from Callistephus chinensis flowers and their inhibitory activities against alpha-glucosidase

Inhibitors of carbohydrate-hydrolysing enzymes play an important role for the treatment of diabetes. One of the therapeutic methods for decreasing of postprandial hyperglycemia is to retard absorption of glucose by the inhibition of carbohydrate-hydrolysing enzymes, such as α-glucosidase, in the digestive organs. To investigate the therapeutic potential of compounds from natural sources, Callistephus chinensis flowers (CCF) were tested for inhibition of α-glucosidase, and acarboes was used as the positive control. The 70 % ethanol extract of CCF exhibited significant α-glucosidase inhibitory activities with IC50 value of 8.14 μg/ml. The stepwise polarity fractions of CCF were tested further for in vitro inhibition of α-glucosidase. The ethyl acetate (EtOAc) fraction exhibited the most significant inhibitory activity. Eight pure compounds, apigenin, apigenin-7-O-β-D-glucoside, kaempferol, hyperin, naringenin, quercetin, luteolin, and kaempferol-7-O-β-D-glucoside, were isolated (using enzyme assay-guide fractionation method) from the EtOAc fraction. Among these, quercetin was the most active one (IC50 values 2.04 μg/ml), and it appears that the inhibiting percentages are close to acarbose (IC50 values 2.24 μg/ml), the positive control, on α-glucosidase inhibition. HPLC/UV analysis indicated that the major components of CCF are kaempferol, hyperin and quercetin. The presented results revealed that CCF containing these eight flavonoids could be a useful natural source in the development of a novel α-glucosidase inhibitory agent against diabetic complications

Innovative approaches for deep decarbonization of data centers and building space heating networks : Modeling and comparison of novel waste heat recovery systems for liquid cooling systems

The data usage surge drives greater data center demand, amplifying global CO2 emissions. Mitigating climate change necessitates reducing data center CO2 emissions. Reusing waste heat from data centers offers a potential energy efficiency boost and environmental impact reduction. This study utilizes liquid cooling technology to raise waste heat temperature for building space heating and introduces the concept of ‘data furnaces,’ where data centers directly supply waste heat to heat buildings on-site, reducing district heating consumption and lowering CO2 emissions. Efficiently designing a heat recovery heat exchanger system that accounts for both heat rejection and cooling sides of a liquid cooling system is crucial for achieving complete heat recovery without using heat pump, a commonly overlooked aspect in existing literature. To address this issue, we propose two heat exchanger schemes: connecting the building space heating network to the secondary side (Scheme 1) and the primary side (Scheme 2) of the cooling distribution unit. Implementing these innovations leads to the elimination of dependence on a heat pump, substantially cutting energy and CO2 emissions. Using TRNSYS software, we develop, model, and compare waste heat recovery schemes to curb district heating consumption and CO2 emissions. To demonstrate broad implications of the proposed approaches for energy efficiency and sustainability in the data centers and building space heating networks, a showcase study examines constant 25 kW waste heat from a direct-to-chip liquid-cooled rack in an office building with 285.7 MWh annual space heating demand. A novel waste heat recovery rate relationship graph is created to assist system design, uncovering an unexpected result in Scheme 2: waste heat recovery decreases as outdoor temperature falls. In contrast, Scheme 1 maintains a stable waste heat recovery rate around 25 kW, regardless of outdoor temperature fluctuations. As a result, Scheme 1 reuses 155.2 MWh of waste heat annually compared to 138 MWh for Scheme 2. Schemes 1 and 2 yield annual electricity savings of 2290.5 kWh and 905.2 kWh, respectively, for the cooling system. Both schemes achieve profitability within a year through a 25-year life cycle analysis (LCC) and substantially reduce CO2 emissions, with Scheme 1 saving 291,996 kgCO2 and Scheme 2 saving 258,192 kgCO2. The study addresses critical gaps in existing literature by emphasizes LCC. The proposed heat exchanger designs represent pioneering solutions for optimizing waste heat recovery, particularly in challenging climates. New findings offer substantial benefits to both liquid-cooled and air-cooled facilities, making significant contributions to achieve carbon neutrality in data center operations.© 2023 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).fi=vertaisarvioitu|en=peerReviewed

Desarrollo y validación de una escala PLEs desde la perspectiva del alumno y el aprendizaje en la educación terciaria

The study's goal is to create and validate a Personal Learning Environment Scale (PLEs) from the learner and learning perspective (named PLEsS-LL) to ensure effective learning in Chinese tertiary education. 657 undergraduates participated in the study after completing scale development steps. Six factors were extracted from the PLEsS-LL using Exploratory Factor Analysis (EFA). Confirmatory Factor Analysis (CFA) supported the six-factor scale with 22 items. Furthermore, the PLEsS-LL was redesigned as a questionnaire to assess learners' readiness for PLE learning. The findings indicated that participants were comfortable learning in PLEs in general. They were mostly positive in terms of learning motivation and problem-solving abilities. They did, however, report less confidence in self-directed learning. Meanwhile, male participants outperformed female participants in all categories except learning motivation. The reasons were explained, and suggestions for future PLE design were made. The PLEsS-LL could be used as a resource or guide for learner preparation in the PLE context in higher education around the world.El objetivo del estudio es crear y validar una Escala de Entornos Personales de Aprendizaje (PLEsS) desde la perspectiva del alumno y el aprendizaje (llamada PLEsS-LL) para garantizar un aprendizaje efectivo en la educación terciaria china. 657 estudiantes universitarios participaron en el estudio después de completar los pasos de desarrollo de escala. Se extrajeron seis factores del PLEsS-LL mediante Análisis Factorial Exploratorio (EFA). El Análisis Factorial Confirmatorio (AFC) apoyó la escala de seis factores con 22 ítems.  Además, el PLEsS-LL fue rediseñado como un cuestionario para evaluar la preparación de los alumnos para el aprendizaje PLE. Los hallazgos indicaron que los participantes se sentían cómodos al aprender en PLE en general. En su mayoría fueron positivos en términos de motivación de aprendizaje y habilidades para resolver problemas. Sin embargo, informaron menos confianza en el aprendizaje autodirigido. Mientras tanto, los participantes masculinos superaron a las participantes femeninas en todas las categorías, excepto en la motivación de aprendizaje. Se explicaron las razones y se hicieron sugerencias para el diseño futuro de PLE. El PLEsS-LL podría utilizarse como un recurso o guía para la preparación del alumno en el contexto de los PLEs en la educación superior de todo el mundo

Evaluating Teachers and Schools Using Student Growth Models

Interest in Student Growth Modeling (SGM) and Value Added Modeling (VAM) arises from educators concerned with measuring the effectiveness of teaching and other school activities through changes in student performance as a companion and perhaps even an alternative to status. Several formal statistical models have been proposed for year-to-year growth and these fall into at least three clusters: simple change (e.g., differences on a vertical scale), residualized change (e.g., simple linear or quantile regression techniques), and value tables (varying salience of different achievement level outcomes across two years). Several of these methods have been implemented by states and districts. This paper reviews relevant literature and reports results of a data-based comparison of six basic SGM models that may permit aggregating across teachers or schools to provide evaluative information. Our investigation raises some issues that may compromise current efforts to implement VAM in teacher and school evaluations and makes suggestions for both practice and research based on the results. Accessed 9,761 times on https://pareonline.net from December 17, 2012 to December 31, 2019. For downloads from January 1, 2020 forward, please click on the PlumX Metrics link to the right

Study on Wear Resistance of Nickel Cladding Layer with Imitation Shell Convex Strip Structure on the Surface of 7075 Aluminum Alloy Drill Pipe

In this study, a nickel cladding layer with a bionic convex strip structure was applied to the surface of an aluminum alloy drill pipe, and laser cladding technology was used to improve the wear resistance of the aluminum alloy drill pipe. Firstly, by observing the morphological characteristics of the shell surface, the ratio of the width of the convex strips to the spacing between the convex strips was obtained as 0.39–0.53, and thus a model of the bionic structure was constructed. Numerical simulations were performed, and the results showed that the wear of the bionic structure was reduced by 77.6% compared with that of the smooth structure. Subsequently, the cladding layers of both structures were coated on the drill pipe using nickel powder as the material, and wear tests were performed. The microstructure, composition, and hardness behavior of the cladding layers were analyzed using scanning electron microscopy, an X-ray diffractometer, and a microhardness tester. It was found that the cladding layer mainly consists of Al3Ni2, and there is a transition layer between the cladding layer and the aluminum alloy matrix, whose hardness is lower than that of Al3Ni2. In addition, the groove space can be formed between the convex strips, which effectively reduces the frequency of the debris flow. The results of the wear tests show that the wear of the cladding layer with the bionic structure is reduced by 74.0%. Similar results in numerical simulations and experiments verified that the designed cladding layer with a bionic convex strip structure can significantly improve the wear resistance of aluminum alloy drill pipes.© 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).fi=vertaisarvioitu|en=peerReviewed

Association of the metabolic score for insulin resistance with cardiovascular diseases, cardiovascular and all-cause mortality in Chinese hypertensive population

ImportanceLittle is known about the relationship between the metabolic score for insulin resistance (METS-IR) and the prognosis of hypertensive patients in China.ObjectiveTo investigate the association between the novel non–insulin‐based METS-IR index and the cardiovascular composite endpoints and all-cause mortality in Chinese hypertensive participants.Design, setting, and participantsThis cohort study used data from the China H-Type Hypertension Project, a long-term prospective cohort consisting of 14234 hypertensive patients in southern China, with a baseline from March to August 2018. The median follow-up period for participants was 3.94 years, as of 2022. The data analysis period is from July 2023 to September 2023.ExposuresMETS-IR index of participants in the Chinese H-type hypertension project. The calculation formula for METS-IR is (Ln (2 × FPG) +TG) × BMI/Ln (HDL-C).Main outcomes and measuresCardiovascular events and cardiovascular, all-cause mortality were identified by linking the cohort database with the health care system through October, 2023.ResultsA total of 14220 participants were included in this study. The prevalence rates of cardiovascular disease (CVD), cardiovascular death, and all-cause death were 2.59% (369/14220), 2.79% (397/14220), and 5.66% (805/14220), respectively. After adjusting for confounding factors in the multivariate logistic regression analysis models, the METS-IR index was significantly positively correlated with CVD, and cardiovascular, all-cause mortality, whether as a categorical or continuous variable. Layered analysis showed that the METS-IR index of hypertensive participants in different subgroups was positively correlated with the endpoint event.Conclusions and relevanceThis large, prospective cohort study demonstrated that the METS-IR index, a new IR evaluation index, were independently associated with a higher risk of the cardiovascular composite endpoint and all-cause mortality among Chinese hypertensive population. Importantly, our finding provides an independent indicator for evaluating the prognosis of hypertensive patients

Incidence and factors associated with the recurrence of Rathke's cleft cyst after surgery: A systematic review and meta-analysis

BackgroudRecurrence of Rathke's cleft cyst (RCC) is not uncommon after surgery, and the associated factors and incidence of relapse deserve a systematic summary.MethodsThis study was conducted in accordance with Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines. The Pubmed, Embase, Cochrane, and Web of Science databases were searched until September 12, 2022. Studies with significant results of recurrent factors or specific incidences of RCC recurrence and mean/median follow-up time were included. Based on a protocol of a 2-year interval grouping, included studies were categorized into four groups with follow-up periods  <24 months, 24–48 months, 48–72 months, and ≥72 months, respectively. Quality assessment was performed using the NOS score. Pooled estimations were computed by using a random-effects model in the STATA “metaprop” command. Publication bias was assessed visually through a funnel plot and statistically through Egger's linear regression test and Begg's correlation test.ResultsA total of 44 studies were included containing 2,539 cases. Squamous metaplasia was the most commonly reported factor, followed by the extent of cyst removal. The other factors were reported individually. The pooled overall incidences of RCC recurrence after surgery in four groups of the follow-up period were 7.4% (95%CI = 4.1–11.3%) in <24 months, 13.1% (95%CI = 9.7–17.0%) in 24–48 months, 13.7% (95%CI = 7.7–21.0%) in 48–72 months, and 33.8% (95%CI = 19.6–49.6%) in ≥72 months. The pooled symptomatic incidences were 2.3% (95%CI = 0.4–5.1%) in <24 months, 5.6% (95%CI = 3.6–7.9%) in 24–48 months, 5.9% (95%CI = 2.4–10.6%) in 48–72 months, and 14.1% (95%CI = 6.0–24.5%) in ≥72 months. A dramatic increase in recurrent incidence was observed when the follow-up period was more than 72 months in both overall and symptomatic recurrence. A similar trend of recurrence was found in subgroup analyses stratified by publication year, cohort size, and cyst resection strategy.ConclusionThis study systematically reviewed recurrent factors and described the profile of trends in RCC recurrent incidence after surgery with a follow-up time based on a protocol of a 2-year interval, finding a dramatic increase in recurrent rates with a follow-up period of more than 72 months. This encouraged us to put forward a recommendation of at least a 6-year follow-up after surgery for patients with RCC.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/, identifier: CRD42021278970

Influence of lunar semidiurnal tides on groundwater dynamics in estuarine aquifers

The influence of lunar semidiurnal tides on coastal groundwater aquifers has been conceptualized for decades. However, a thorough understanding of the impact of tides on groundwater dynamics due to the widely distributed waterways and heterogeneous sediments in estuarine aquifers, is still needed. This study shows the tidal impact on groundwater dynamics in the Pearl River estuary in southeast China through wavelet and time series analysis. The groundwater level and electrical conductivity (EC), as well as tidal levels, were monitored in several observation wells and tidal stations to determine how the estuarine groundwater levels respond to tidal forcing. The results show that the groundwater fluctuations have short periodicities of 0.51 and 1 day corresponding to major tidal constituents of M2 (semidiurnal) and K1 and O1 (diurnal) signals, respectively. The significant impacts decrease with increasing distance inland of the locations of the wells. Additionally, the coherence analysis displays a higher correlation between tides and groundwater levels for the spring tide than for the neap tide. The tidal influences on groundwater EC are weak compared to those on groundwater levels. In addition, when the tidal level increases, the EC decreases in wells located in the estuarine entrance. This is related to the high salinity of retained paleo-seawater in the strata lenses. A conceptual model is proposed to illustrate the complex groundwater flow dynamics. The model may provide useful insights into the understanding of similar systems located in geographically different coastal regions.© 2020 Springer. This is a post-peer-review, pre-copyedit version of an article published in Hydrogeology Journal. The final authenticated version is available online at: http://dx.doi.org/10.1007/s10040-020-02136-8fi=vertaisarvioitu|en=peerReviewed