Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

Iron Carbide Nanoparticles Embedded in Edge-Rich, N and F Codoped Graphene/Carbon Nanotubes Hybrid for Oxygen Electrocatalysis

Rational design of cost-effective and efficient bifunctional oxygen electrocatalysts for sluggish oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) is urgently desired for rechargeable metal–air batteries and regenerative fuel cells. Here, the Fe3C nanoparticles encapsulated in N and F codoped and simultaneously etched graphene/CNTs architecture catalyst (Fe3C@N-F-GCNTs) was synthesized by a simple yet cost-effective strategy. The as-prepared Fe3C@N-F-GCNTs exhibited excellent ORR and OER performances, with the ORR half-wave potential positive than that of Pt/C by 14 mV, and the OER overpotential lowered to 432 mV at the current density of 10 mA·cm−2. In addition, the ΔE value (oxygen electrode activity parameter) increased to 0.827 V, which is comparable to the performance of the best nonprecious metal catalysts reported to date. When it was applied in a Zn–air battery as a cathode, it achieved a peak power density of 130 mW·cm−2, exhibiting the potential for large-scale applications

Iron Carbide Nanoparticles Embedded in Edge-Rich, N and F Codoped Graphene/Carbon Nanotubes Hybrid for Oxygen Electrocatalysis

Rational design of cost-effective and efficient bifunctional oxygen electrocatalysts for sluggish oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) is urgently desired for rechargeable metal–air batteries and regenerative fuel cells. Here, the Fe3C nanoparticles encapsulated in N and F codoped and simultaneously etched graphene/CNTs architecture catalyst (Fe3C@N-F-GCNTs) was synthesized by a simple yet cost-effective strategy. The as-prepared Fe3C@N-F-GCNTs exhibited excellent ORR and OER performances, with the ORR half-wave potential positive than that of Pt/C by 14 mV, and the OER overpotential lowered to 432 mV at the current density of 10 mA·cm−2. In addition, the ΔE value (oxygen electrode activity parameter) increased to 0.827 V, which is comparable to the performance of the best nonprecious metal catalysts reported to date. When it was applied in a Zn–air battery as a cathode, it achieved a peak power density of 130 mW·cm−2, exhibiting the potential for large-scale applications

Plate Waste in School Lunch Programs in Beijing, China

School plate waste is of particular concern worldwide due to its adverse impacts not only on resource use and the environment, but also on students’ health, physical maturation, and academic achievement in the long term. Previous studies on school plate waste have all been conducted in industrialized countries, and more studies are badly needed in developing countries. In this paper, we report a pilot study on the patterns and causes of plate waste in school lunch programs in Beijing, China, by a combination of physical weighing, questionnaire survey, and semi-structured interview approaches. Our results show that the average amount of food waste generated by school students in Beijing in 2014 was 130 g/cap/meal, accounting for 21% of total food served. Staple food (43%) and vegetables (42%) were the dominant proportions. Buffet meals resulted in less plate waste than packed meals and set meals. Food supply patterns, the quality of canteen service, and the dietary habit and students’ knowledge of food production were the main influencing factors behind plate waste. To our best knowledge, our pilot study provides a first understanding of the overlooked plate waste in school lunch programs in China, and a good basis for further analysis in this field, and will be helpful in informing policy-making in relevant nutrition and education programs in schools in China

Changing Food Consumption Patterns and Impact on Water Resources in the Fragile Grassland of Northern China

A burgeoning population, pressing development needs and increasing household consumption are rapidly accelerating water use in direct and indirect ways. Increasingly, regions around the world face growing pressure on sustainable use of their water resources especially in arid and semi-arid regions, such as Northern China. The aim of this research is to obtain an overview of the cumulative water requirement for direct (domestic) water use and indirect water use for the basic food consumption of the households in the Inner Mongolia Autonomous Region (IMAR), in order to reduce the pressure on grassland of Western China by encouraging sustainable water consumption. For indirect water use, we use VWC (virtual water content) analysis theory to analyze the total consumption package of 15 basic food types that were identified and quantified based on the household survey in 2011. In this survey, domestic water consumption data and food consumption data were collected from 209 representative households with spatial variation across three sub-regions (including meadow steppe in Hulun Buir, typical steppe in Xilin Gol, and semi-desert steppe in Ordos) and temporal variation from 1995 to 2010. The results show that the total amounts of food consumption per capita in three sub-regions all show an increasing trend, especially in Hulun Buir and Ordos. Compared to the direct water consumption, the indirect water consumption behind food production made up a major portion of total water consumption, which is affected (1) geographic locations (grassland types); (2) economic development levels and (3) grassland use policy measures. From 1995 to 2010, indirect water consumption displays a decreasing trend in Xilin Gol and Ordos due to the decrease of meat consumption and increase of fruit and vegetable consumption. When considering the amount of land per household, the grassland in Ordos still faces the great threat of high water consumption pressure. Such water consumption may affect water conservation services and productivity of grassland. Therefore, changing diet behavior and reducing the population can be considered options for sustainable use of water