Dysnatremia is associated with increased risk of all-cause mortality within 365 days post-discharge in patients with atrial fibrillation without heart failure: A prospective cohort study

Aim: The aim of this study is to evaluate the association between serum sodium concentrations at hospital admission and all-cause mortality within 365 days post-discharge in patients with atrial fibrillation (AF) without heart failure (HF). Methods: The prospective cohort study enrolled 1,446 patients with AF without HF between November 2018 and October 2020. A follow-up was performed 30, 90, 180, and 365 days after enrollment through outpatient visits or telephone interviews. All-cause mortality was estimated in three groups according to serum sodium concentrations: hyponatremia ( \u3c 135 mmol/L), normonatremia (135 – 145 mmol/L), and hypernatremia ( \u3e 145 mmol/L). We estimated the risk of all-cause mortalities using univariable and multivariable Cox proportional hazards models with normonatremia as the reference. Results: The all-cause mortalities of hyponatremia, normonatremia, and hypernatremia were 20.6, 9.4, and 33.3 % within 365 days post-discharge, respectively. In the univariable analysis, hyponatremia (HR: 2.19, CI 1.5 – 3.2) and hypernatremia (HR: 4.03, CI 2.32 – 7.02) increased the risk of all-cause mortality. The HRs for hyponatremia and hypernatremia were 1.55 (CI 1.05 – 2.28) and 2.55 (CI 1.45 – 4.46) after adjustment for age, diabetes mellitus, loop diuretics, antisterone, antiplatelet drugs, and anticoagulants in the patients with AF without HF. The association between serum sodium concentrations and the HRs of all-cause mortality was U-shaped. Conclusion: Dysnatremia at hospital admission was an independent factor for all-cause mortality in patients with AF without HF within 365 days post-discharge

Stomatal response to decreased relative humidity constrains the acceleration of terrestrial evapotranspiration

Terrestrial evapotranspiration (ET) is thermodynamically expected to increase with increasing atmospheric temperature; however, the actual constraints on the intensification of ET remain uncertain due to a lack of direct observations. Based on the FLUXNET2015 Dataset, we found that relative humidity (RH) is a more important driver of ET than temperature. While actual ET decrease at reduced RH, potential ET increases, consistently with the complementary relationship (CR) framework stating that the fraction of energy not used for actual ET is dissipated as increased sensible heat flux that in turn increases potential ET. In this study, we proposed an improved CR formulation requiring no parameter calibration and assessed its reliability in estimating ET both at site-level with the FLUXNET2015 Dataset and at basin-level. Using the ERA-Interim meteorological dataset for 1979-2017 to calculate ET, we found that the global terrestrial ET showed an increasing trend until 1998, while the trend started to decline afterwards. Such decline was largely associated with a reduced RH, inducing water stress conditions that triggered stomatal closure to conserve water. For the first time, this study quantified the global-scale implications of changes in RH on terrestrial ET, indicating that the temperature-driven acceleration of the terrestrial water cycle will be likely constrained by terrestrial vegetation feedbacks.Peer reviewe

Facile synthesis of LiCoO2 nanowires with high electrochemical performance

Cobalt precursor Co(CO3)(0.35)Cl-0.2(OH)(1.1) nanowire bunches have been synthesized by a hydrothermal method and transformed into Co3O4 nanowires by calcination at 500 A degrees C for 3 h. The Co3O4 nanowires were then mixed with LiOH and formed the LiCoO2 nanowires by calcination at 750 A degrees C. High resolution transmission electron microscopy revealed that the LiCoO2 nanowires were composed of nanoparticles with most of the nanoparticles having exposed (010) planes. The electrochemical performance of the LiCoO2 nanowires was thoroughly investigated by galvanostatic tests. The as-prepared LiCoO2 nanowires exhibited excellent rate capability and satisfactory cycle stability, where the charge and discharge capacity still stabilized at 100 mA center dot h/g at a rate of 1000 mA/g after 100 cycles. The favorable electrochemical performance of the LiCoO2 nanowires may result from their one-dimensional nanostructure and the exposure of (010) planes, since the (010) plane is electrochemically active for layered LiCoO2 with the alpha-NaFeO2 structure and favors fast Li+ transportation

Autoinducer-2-mediated quorum sensing partially regulates the toxic shock response of anaerobic digestion

This study discovered a strong correlation between the autoinducer-2 (AI-2)-mediated quorum sensing (QS) with the performance of a submerged anaerobic membrane bioreactor during its recovery from a pentachlorophenol (PCP) shock: a decrease in AI-2 levels coincided with a reduction in volatile fatty acid concentrations, and corresponded significantly to a decrease in the relative abundance of Firmicutes, and to an increase in the relative abundance of Bacteroidetes and Synergistetes. Further batch experiments with the addition of an AI-2-regulating Escherichia coli mutant culture showed that a reduction in AI-2 levels resulted in the highest biogas production rate during a PCP shock. In contrast, an increase in AI-2 levels via addition of the E. coli wild type strain or an AI-2 precursor showed no obvious effects on biogas production. These results suggest that the AI-2 level in anaerobic sludge was governed primarily by Firmicutes, and the AI-2-mediated QS partially regulates the toxic shock response of anaerobic sludge via tuning the activities of Firmicutes and Synergistetes. A decrease in the AI-2 level might reduce acetogenesis and favor hydrogenotrophic methanogenesis, thus resulting in less VFA accumulation and higher methane production during the PCP shock. This study is the first of this type that exploits the role of quorum sensing in the toxic shock response of anaerobic sludge; it demonstrates a novel approach to shortening the recovery period of anaerobic processes via manipulating the AI-2-mediated QS.National Research Foundation (NRF)The project was supported and administrated by the Environment & Water Industry Programme Office (EWI) for and on behalf of the National Research Foundation Board (NRF), Singapore (EWI-IRIS-0807). The project was also supported by the Shantou University Scientific Research Foundation for Talents (No.: NTF16015) and the National Natural Science Foundation of China (No.: 51750110514)

Size-dependent microbial diversity of sub-visible particles in a submerged anaerobic membrane bioreactor (SAnMBR) : implications for membrane fouling

Sub-visible particles, an often-overlooked fine particle (0.45–10 μm) with a size between sludge solids and soluble microbial products (SMP), have recently been identified as a critical foulant in anaerobic membrane bioreactors (AnMBRs), and our recent new insights into the size-fractionation and composition of sub-visible particles in AnMBRs have enabled fouling to be understood in more depth. Here, we investigated the microbial diversity of the sub-visible particles in three size fractions (i.e., 5–10, 1–5, and 0.45–1 μm) from bulk and cake solutions in a lab-scale AnMBR, and their fouling potential was further explored based on their filtration behavior and biofilm formation. Results show that with decreasing particle size, a significant shift in microbial communities was observed for the sub-visible particles in both bulk and cake solutions; (a) with notable decreases in filamentous microbes in the order SJA-15, GCA004, and Anaerolineales of phylum Chloroflexi, and, (b) with substantial increases in sulfate-reducing bacteria (i.e., the family Syntrophobacteraceae, genus DCE29 of family Thermodesulfovibrionaceae, Desulfovibrio, and Geobacter). More importantly, the filamentous microbes associated with micro-particles (5–10 μm) led to higher cake fouling resistances while free living cells in the form of colloidal particles (0.45–1 μm) induced severer pore blocking. Moreover, the micro-particles had an enhanced capacity to favor biofilm formation (OD595 = 1.0–2.5, categorized as highly positive), thus potentially aggravating biofouling. This work advances our knowledge on the effect of particle size on communities and underlying fouling behavior of microbes associated with fine particles in AnMBRs.Environment & Water Industry Development Council (EWI)This work was funded by the Environmental & Water Industry Programme Office (PUB IDD 21100/36/6) in Singapore. It was also supported by the National Natural Science Foundation of China (No. 51608546) and the Fundamental Research Funds for the Central Universities (No. 17lgpy94). We are grateful to Dr. Guangyi Su for support with community analysis

An experimental study on separating temperature and emissivity of a nonisothermal surface

This letter presents an experiment to explore the nonisothermal effects on temperature and emissivity separation (TES). The innovation of this experiment lies in its design, which highlights the contrast between isothermal and nonisothermal conditions in emissivity measurements. We artificially created a sharply contrasting nonisothermal soil surface using liquid nitrogen cooling and solar heating. The iterative spectrally smooth TES (ISSTES) algorithm was used to process the experimental data. The analyzed results of the experimental data show that the nonisothermal conditions have a significant effect on TES. The bias of retrieved emissivity increases with the component temperature difference as well as with wavelength. The bias around the split window band can reach up to 1% when the difference of the component temperature is 40K. Considering that 1% error in emissivity can cause approximately 1K error of retrieved land surface temperature (LST), the nonisothermal effects on emissivity cannot be ignored. We hope that this experiment will arouse attention of the nonisothermal effects on TES and call for more efforts to be devoted to this issue in the future