1,867 research outputs found
A Semantic Grid Oriented to E-Tourism
With increasing complexity of tourism business models and tasks, there is a
clear need of the next generation e-Tourism infrastructure to support flexible
automation, integration, computation, storage, and collaboration. Currently
several enabling technologies such as semantic Web, Web service, agent and grid
computing have been applied in the different e-Tourism applications, however
there is no a unified framework to be able to integrate all of them. So this
paper presents a promising e-Tourism framework based on emerging semantic grid,
in which a number of key design issues are discussed including architecture,
ontologies structure, semantic reconciliation, service and resource discovery,
role based authorization and intelligent agent. The paper finally provides the
implementation of the framework.Comment: 12 PAGES, 7 Figure
Proteomic analysis of the rat ovary following chronic low-dose exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a ubiquitously distributed endocrine-disrupting chemical and reproductive toxicant. In order to elucidate low-dose TCDD-mediated effects on reproductive or endocrine functions, female Sprague-Dawley rats were orally administered various concentrations (20, 50, or 125 ng/kg once weekly) TCDD for 29 wk. A proteomic analysis of the ovaries by two-dimensional gel electrophoresis and matrix-assisted laser desorption/ionization (MALDI) tandem mass spectrometry showed distinct changes in the levels of several proteins that are relevant markers of TCDD toxicity. Serum estradiol (E2) levels of TCDD-treated animals were markedly lower than control. There were no significant differences in bone mineral density (BMD) of femurs. The body weight of the 125-ng/kg TCDD group was significantly decreased relative to control and there was also a significant reduction in absolute and relative ovarian weights. Expressions of selenium binding protein 2, glutathione S-transferase mu type 3, Lrpap1 protein, NADPH, and peptidylprolyl isomerase D were upregulated, while prohibitin and N-ethylmaleimide-sensitive factor expression levels were downregulated. Data provide further insight into the mechanisms by which TCDD disrupts ovarian function by indicating which differential protein expressions following low-dose TCDD exposure
Drying of the Qaidam basin and its controlling factors deduced from core SG-1
Abstract HKT-ISTP 2013
B
NARROMI: a noise and redundancy reduction technique improves accuracy of gene regulatory network inference.
MOTIVATION: Reconstruction of gene regulatory networks (GRNs) is of utmost interest to biologists and is vital for understanding the complex regulatory mechanisms within the cell. Despite various methods developed for reconstruction of GRNs from gene expression profiles, they are notorious for high false positive rate owing to the noise inherited in the data, especially for the dataset with a large number of genes but a small number of samples.
RESULTS: In this work, we present a novel method, namely NARROMI, to improve the accuracy of GRN inference by combining ordinary differential equation-based recursive optimization (RO) and information theory-based mutual information (MI). In the proposed algorithm, the noisy regulations with low pairwise correlations are first removed by using MI, and the redundant regulations from indirect regulators are further excluded by RO to improve the accuracy of inferred GRNs. In particular, the RO step can help to determine regulatory directions without prior knowledge of regulators. The results on benchmark datasets from Dialogue for Reverse Engineering Assessments and Methods challenge and experimentally determined GRN of Escherichia coli show that NARROMI significantly outperforms other popular methods in terms of false positive rates and accuracy.
AVAILABILITY: All the source data and code are available at: http://csb.shu.edu.cn/narromi.htm
Energy, interaction, and photoluminescence of spin-reversed quasielectrons in fractional quantum Hall systems
The energy and photoluminescence spectra of a two-dimensional electron gas in
the fractional quantum Hall regime are studied. The single-particle properties
of reversed-spin quasielectrons (QE's) as well as the
pseudopotentials of their interaction with one another and with Laughlin
quasielectrons (QE's) and quasiholes (QH's) are calculated. Based on the
short-range character of the QE--QE and QE--QE
repulsion, the partially unpolarized incompressible states at the filling
factors and are postulated within Haldane's
hierarchy scheme. To describe photoluminescence, the family of bound
QE states of a valence hole and QE's are
predicted in analogy to the found earlier fractionally charged excitons
QE. The binding energy and optical selection rules for both families are
compared. The QE is found radiative in contrast to the dark QE,
and the QE is found non-radiative in contrast to the bright
QE.Comment: 9 pages, 6 figure
Analysis of the doubly heavy baryons in the nuclear matter with the QCD sum rules
In this article, we study the doubly heavy baryon states ,
, and in the nuclear matter using the QCD
sum rules, and derive three coupled QCD sum rules for the masses, vector
self-energies and pole residues. The predictions for the mass-shifts in the
nuclear matter , , and
can be confronted with the
experimental data in the future.Comment: 10 pages, 4 figure
Quantum Ferromagnetism and Phase Transitions in Double-Layer Quantum Hall Systems
Double layer quantum Hall systems have interesting properties associated with
interlayer correlations. At where is an odd integer they exhibit
spontaneous symmetry breaking equivalent to that of spin easy-plane
ferromagnets, with the layer degree of freedom playing the role of spin. We
explore the rich variety of quantum and finite temperature phase transitions in
these systems. In particular, we show that a magnetic field oriented parallel
to the layers induces a highly collective commensurate-incommensurate phase
transition in the magnetic order.Comment: 4 pages, REVTEX 3.0, IUCM93-013, 1 FIGURE, hardcopy available from:
[email protected]
Running coupling: Does the coupling between dark energy and dark matter change sign during the cosmological evolution?
In this paper we put forward a running coupling scenario for describing the
interaction between dark energy and dark matter. The dark sector interaction in
our scenario is free of the assumption that the interaction term is
proportional to the Hubble expansion rate and the energy densities of dark
sectors. We only use a time-variable coupling (with the scale factor
of the universe) to characterize the interaction . We propose a
parametrization form for the running coupling in which the
early-time coupling is given by a constant , while today the coupling is
given by another constant, . For investigating the feature of the running
coupling, we employ three dark energy models, namely, the cosmological constant
model (), the constant model (), and the time-dependent
model (). We constrain the models with the current
observational data, including the type Ia supernova, the baryon acoustic
oscillation, the cosmic microwave background, the Hubble expansion rate, and
the X-ray gas mass fraction data. The fitting results indicate that a
time-varying vacuum scenario is favored, in which the coupling crosses
the noninteracting line () during the cosmological evolution and the sign
changes from negative to positive. The crossing of the noninteracting line
happens at around , and the crossing behavior is favored at about
1 confidence level. Our work implies that we should pay more attention
to the time-varying vacuum model and seriously consider the phenomenological
construction of a sign-changeable or oscillatory interaction between dark
sectors.Comment: 8 pages, 5 figures; refs added; to appear in EPJ
The pole in
Using a sample of 58 million events recorded in the BESII detector,
the decay is studied. There are conspicuous
and signals. At low mass, a large
broad peak due to the is observed, and its pole position is determined
to be - MeV from the mean of six analyses.
The errors are dominated by the systematic errors.Comment: 15 pages, 6 figures, submitted to PL
Measurements of Cabibbo Suppressed Hadronic Decay Fractions of Charmed D0 and D+ Mesons
Using data collected with the BESII detector at storage ring
Beijing Electron Positron Collider, the measurements of relative branching
fractions for seven Cabibbo suppressed hadronic weak decays ,
, and , , and are presented.Comment: 11 pages, 5 figure
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