5,811 research outputs found

    Recent CMS searches for exotic phenomena beyond the Standard Model

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    The results of several recent CMS searches for exotic phenomena beyond the Standard Model are presented in this talk. Two searches look for new physics in a final state with a vector boson and missing transverse energy. Three searches target massive resonances decaying to a Higgs boson and a vector boson. Finally, preliminary results are presented for the first CMS search for exotic phenomena using s=13\sqrt{s} = 13 TeV data, the search for dijet resonances.Comment: Presentation at the DPF 2015 Meeting of the American Physical Society Division of Particles and Fields, Ann Arbor, Michigan, August 4-8, 201

    Thinking outside the beamspot: Other SUSY searches at the LHC (long-lived particles and R-parity violation)

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    Supersymmetric particles that are long-lived or violate R-parity could evade many conventional searches for supersymmetry. This talk presents the latest results of searches for supersymmetry with long-lived particles or R-parity violation performed by the ATLAS and CMS collaborations using ∼\sim20 fb−1^{-1} of proton-proton collisions at center-of-mass energy of 8 TeV delivered by the LHC.Comment: Submitted to Proceedings of Rencontres de Moriond QCD 201

    Depression and mortality: Artifact of measurement and analysis?

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    Background Previous research demonstrates various associations between depression, cardiovascular disease (CVD) incidence and mortality, possibly as a result of the different methodologies used to measure depression and analyse relationships. This analysis investigated the association between depression, CVD incidence (CVDI) and mortality from CVD (MCVD), smoking related conditions (MSRC), and all causes (MALL), in a sample data set, where depression was measured using items from a validated questionnaire and using items derived from the factor analysis of a larger questionnaire, and analyses were conducted based on continuous data and grouped data. Methods Data from the PRIME Study (N=9798 men) on depression and 10-year CVD incidence and mortality were analysed using Cox proportional hazards models. Results Using continuous data, both measures of depression resulted in the emergence of positive associations between depression and mortality (MCVD, MSRC, MALL). Using grouped data, however, associations between a validated measure of depression and MCVD, and between a measure of depression derived from factor analysis and all measures of mortality were lost. Limitations Low levels of depression, low numbers of individuals with high depression and low numbers of outcome events may limit these analyses, but levels are usual for the population studied. Conclusions These data demonstrate a possible association between depression and mortality but detecting this association is dependent on the measurement used and method of analysis. Different findings based on methodology present clear problems for the elucidation and determination of relationships. The differences here argue for the use of validated scales where possible and suggest against over-reduction via factor analysis and grouping. CrownCopyright © 2013PublishedbyElsevierB.V.Allrightsreserved

    A Hierarchical Dirichlet Process Model with Multiple Levels of Clustering for Human EEG Seizure Modeling

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    Driven by the multi-level structure of human intracranial electroencephalogram (iEEG) recordings of epileptic seizures, we introduce a new variant of a hierarchical Dirichlet Process---the multi-level clustering hierarchical Dirichlet Process (MLC-HDP)---that simultaneously clusters datasets on multiple levels. Our seizure dataset contains brain activity recorded in typically more than a hundred individual channels for each seizure of each patient. The MLC-HDP model clusters over channels-types, seizure-types, and patient-types simultaneously. We describe this model and its implementation in detail. We also present the results of a simulation study comparing the MLC-HDP to a similar model, the Nested Dirichlet Process and finally demonstrate the MLC-HDP's use in modeling seizures across multiple patients. We find the MLC-HDP's clustering to be comparable to independent human physician clusterings. To our knowledge, the MLC-HDP model is the first in the epilepsy literature capable of clustering seizures within and between patients.Comment: ICML201

    Symptoms of depression and cardiovascular reactions to acute psychological stress: Evidence from a population study

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    Depression and exaggerated cardiovascular reactivity are considered risk factors for cardiovascular disease, possibly as a result of common antecedents, such as altered autonomic nervous system function. We examined the association between depressive symptomatology and cardiovascular reactions to psychological stress in 1608 adults (875 women) comprising three distinct age cohorts: 24-, 44-, and 63-year olds. Depression was assessed using the Hospital Anxiety and Depression Scale. Blood pressure and heart rate were measured at baseline and during the paced auditory serial arithmetic test. Depression scores were negatively associated with systolic blood pressure and heart rate reactions, after adjustment for likely confounders such as sex, cohort, occupational status, body mass index, stress task performance score, baseline cardiovascular activity, antidepressant and antihypertensive medication. The direction of association was opposite to that which would be expected if excessive reactivity were to mediate the association between depression and cardiovascular disease outcomes or if they shared common antecedents

    Blunted cardiovascular reactivity relates to depression, obesity, and self-reported health

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    The reactivity hypothesis implicates exaggerated cardiovascular reactions to acute psychological stress in the development of hypertension and other cardiovascular disease outcomes. However, cardiovascular reactivity has also been suggested as a mediator between a variety of psychosocial and behavioural risk factors and cardiovascular disease. Data from various analyses of the West of Scotland Twenty-07 study are discussed together, and caution against over-stretching the original reactivity hypothesis. Blood pressure and heart rate were assessed at rest and during an acute mental arithmetic stress task. First, depression, though a putative risk factor for cardiovascular disease, does not appear to confer this risk via exaggerated reactivity, as it was negatively related to reactivity. Second, obesity, another risk factor, was also associated with blunted rather than heightened reactivity. Finally, lower reactivity was related to poorer self-reported health. Similar associations emerged from both cross-sectional and prospective analyses. These seemingly paradoxical results are discussed in terms of implications for the reactivity hypothesis
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