23 research outputs found

    Een patient met gecompliceerd verlopende shigellose

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    Contains fulltext : 4436.pdf (publisher's version ) (Open Access

    Behandeling en profylaxe van gegeneraliseerde mycosen

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    Contains fulltext : 21566___.PDF (publisher's version ) (Open Access

    Herkenning en behandeling van febris typhoidea

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    Contains fulltext : 4437.pdf (publisher's version ) (Open Access

    Bacteriëmieën door niet-typheuze salmonellae: een retrospectief onderzoek bij 33 volwassenen

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    Contains fulltext : 4446.pdf (publisher's version ) (Open Access

    [New developments in antifungal therapy: fluconazole, itraconazole, voriconazole, caspofungin]

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    Contains fulltext : 58922.pdf (publisher's version ) (Closed access)The azole antifungal voriconazole and the echinocandin caspofungin have recently become available for the treatment of invasive mycoses. Fluconazole remains the drug of choice for candidemia, except for infections with one of the resistent species such as Candida krusei and some strains of Candida glabrata. In these cases, as well as in patients who cannot tolerate azoles in connection with side effects or drug interactions, caspofungin is an attractive alternative. Voriconazole has become the drug of choice for severe invasive aspergillosis. Itraconazole is a good alternative for milder and chronic forms of aspergillosis. The use of conventional amphotericin B will be limited by the availability of the new drugs. In view of their high costs, the lipid-bound forms of amphotericin B will usually be given only as salvage therapy in case of failure, in patients who are unable to tolerate either conventional amphotericin or one of the newer agents, and for the treatment of zygomycosis
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