Large droplet impact on water layers

The impact of large droplets onto an otherwise undisturbed layer of water is considered. The work, which is motivated primarily with regard to aircraft icing, is to try and help understand the role of splashing on the formation of ice on a wing, in particular for large droplets where splash appears, to have a significant effect. Analytical and numerical approaches are used to investigate a single droplet impact onto a water layer. The flow for small times after impact is determined analytically, for both direct and oblique impacts. The impact is also examined numerically using the volume of fluid (VOF) method. At small times there are promising comparisons between the numerical results, the analytical solution and experimental work capturing the ejector sheet. At larger times there is qualitative agreement with experiments and related simulations. Various cases are considered, varying the droplet size to layer depth ratio, including surface roughness, droplet distortion and air effects. The amount of fluid splashed by such an impact is examined and is found to increase with droplet size and to be significantly influenced by surface roughness. The makeup of the splash is also considered, tracking the incoming fluid, and the splash is found to consist mostly of fluid originating in the layer

A hybrid parametrical wave prediction model

The development of a numerical wave prediction model incorporating a parametrical wind-sea model and a characteristic swell model is described. The parametrical model is an extension of an earlier two-parameter model to the full five Jonswap spectral parameters. An application is presented in which the model is used to hindcast severe wave conditions in the North Sea as part of an engineering study to define long-term extreme wave statistics for the area. The limitations of the model and the needs for future research are discussed

Association of the CCR5 gene with juvenile idiopathic arthritis

The CC chemokine receptor 5 (CCR5) has been shown to be important in the recruitment of T-helper cells to the synovium, where they accumulate, drive the inflammatory process and the consequent synovitis and joint destruction. A 32 base-pair insertion/deletion variant (CCR5Δ32) within the gene leads to a frame shift and a nonfunctional receptor. CCR5Δ32 has been investigated for its association with juvenile idiopathic arthritis (JIA), with conflicting results. The aim of this study was to investigate whether CCR5Δ32 is associated with JIA in an UK population. CCR5Δ32 was genotyped in JIA cases (n=1054) and healthy controls (n=3129) and genotype and allele frequencies were compared. A meta-analysis of our study combined with previously published studies was performed. CCR5Δ32 was significantly associated with protection from developing JIA, in this UK data set (P(trend)=0.006, odds ratio (OR) 0.79 95% confidence interval (95% CI): 0.66-0.94). The meta-analysis of all published case-control association studies confirmed the protective association with JIA (P=0.001 OR 0.82 95% CI: 0.73-0.93). CCR5Δ32 is a functional variant determining the number of receptors on the surface of T cells, and it is hypothesized that the level of CCR5 expression could influence the migration of proinflammatory T cells into the synovium and thus susceptibility to JIA

Drop Splashing on a Dry Smooth Surface

The corona splash due to the impact of a liquid drop on a smooth dry substrate is investigated with high speed photography. A striking phenomenon is observed: splashing can be completely suppressed by decreasing the pressure of the surrounding gas. The threshold pressure where a splash first occurs is measured as a function of the impact velocity and found to scale with the molecular weight of the gas and the viscosity of the liquid. Both experimental scaling relations support a model in which compressible effects in the gas are responsible for splashing in liquid solid impacts.Comment: 11 pages, 4 figure

Association of the AFF3 gene and IL2/IL21 gene region with juvenile idiopathic arthritis

Recent genetic studies have led to identification of numerous loci that are associated with susceptibility to autoimmune diseases. The strategy of using information from these studies has facilitated the identification of novel juvenile idiopathic arthritis (JIA) susceptibility loci, specifically, PTPN22 and IL2RA. Several novel autoimmune susceptibility loci have recently been identified, and we hypothesise that single-nucleotide polymorphisms (SNPs) within these genes may also be JIA susceptibility loci. Five SNPs within the genes AFF3, IL2/IL21, IL7R, CTLA4 and CD226, previously associated with multiple autoimmune diseases were genotyped, in a large data set of Caucasian JIA patients and controls, and tested for association with JIA. We identified two susceptibility loci for JIA, AFF3 and the IL2/IL21 region and additional weak evidence supporting an association with the CTLA4 and IL7R genes, which warrant further investigation. All results require validation in independent JIA data sets. Further characterisation of the specific causal variants will be required before functional studies can be performed

Management of Trickle Irrigated Orchards for Increased Water Use Efficiency

Trickle irrigation is the most efficient method of irrigating peach orchards in Texas. With a trickle irrigation system, a producer may make full use of a limited or low-volume water supply to apply precise amounts of water to the root zones of individual trees. Improved irrigation scheduling methods offer the potential for further savings in water and energy to pressurize the water since peach trees require less than a fully-watered state for production. This report describes research to determine the crop coefficients for peach trees that would result in an optimum irrigation schedule. One major effort evaluated the physiological response of the peach tree to varying irrigation regimes. This thrust indicated that a crop coefficient as low as 0.53 produced similar physiological responses (leaf water potential, leaf resistance, and transpiration rate) as a crop coefficient of 0.7. The critical period for initiation of stress was during the period before harvest. A large twin weighing lysimeter facility was designed and installed. Preliminary results for mature peach trees showed water use rates at the maximum evapotranspiration rate approached a crop coefficient of 1.0. The research indicates that the peach tree is a luxury consumer of water; improved irrigation scheduling is achievable

Plant Responses of Drip Irrigated Trees to Climate and Water Stress

Past irrigation research has shown that peach (prunus persica) trees vary in their field response to water stress, and the degree of stress is a function of the plants' environment. Water deficits reduce plant growth and crop yields, therefore, measurements of plant water stress are fundamental in understanding how the environment affects plant performance. This in turn will facilitate the irrigator to have very precise water control and to determine optimum irrigation quantities. This research examined the effect of environmental variables on leaf water potential, leaf resistance, canopy resistance and transpiration rate; and evaluated their ultimate effect on yield, water use efficiency and pruning weights for trees under four drip irrigation regimes at Stephenville, Texas. Treatments selected were instrumented with 1-, 2-, 3- and 4-emitters per tree, and single trees from each treatment were instrumented with ground covers. Plant responses were measured hourly on sunlit and shaded leaves of each treatment. Leaf water potentials and leaf resistances were higher in shaded leaves, resulting in reduced transpiration. An increase in early morning leaf water potentials indicated irrigation had decreased stress. Lower leaf water potentials and higher leaf resistance indicated the tress were being severely stressed prior to harvest. Leaf water potentials decreased linearly, whereas leaf resistance decreased exponentially, with increasing solar radiation. In stressed trees critical leaf water potentials were lower suggesting some degree of adaptation to stress. Leaf water potentials decreased linearly with increasing transpiration. Total resistance (sum of plant and soil resistance) increased with increasing severity of stress. The 3-emitter tree was recommended, since yield and water use efficiency are relatively high. Proper irrigation increased total yields and also the number of fruit within a marketable size range, while maintaining high water use efficiency, resulting in economic benefits to the farmer