8,241 research outputs found
Estimating rainfall erosivity from daily precipitation records: a comparison among methods using data from the Ebro Basin (NE Spain)
Among the major factors controlling soil erosion, as vegetation cover or soil erodibility, rainfall erosivity
has a paramount importance since it is difficult to predict and control by humans. Accurate estimation of rainfall erosivity requires continuous rainfall data; however, such data rarely demonstrate good spatial
and temporal coverage. Daily weather records are now commonly available, providing good coverage that better represents rainfall intensity behavior than do more aggregated rainfall data. In the present study annual rainfall erosivity was estimated from daily rainfall records, and compared to data obtained employing the RUSLE R factor procedure. A spatially-dense precipitation database of high temporal resolution (15 min) was used. Two methodologies were applied: (i) daily rainfall erosivity estimated using several parametric models, and, (ii) annual rainfall erosivity estimated by regression-based techniques
employing several intensity precipitation indices and the modified Fournier index. To determine the accuracy of estimates, several goodness-of-fit and error statistics were computed in addition to a spatial distribution comparison. The daily rainfall erosivity models accurately predicted annual rainfall erosivity. Parametric models with few combined parameters and a periodic function simulating intra-annual rainfall
behavior provided the best results. Where daily rainfall records were not available, good estimates of annual rainfall erosivity were also obtained using regression-based techniques based on 5-day maximum precipitation events, the maximum wet spell duration, and the ratio between the lengths of average wet and dry spells. Inherent limitations remain in the use of daily weather records for estimating rainfall erosivity. Future research should focus on incorporating measures of natural rainfall properties of the particular region, including kinetic energy and intensity, and their effects on the soil.We thank the Ebro River Hydrographical Confederation (Confederación Hidrográfica del Ebro; CHE) for providing the data used
in this study. The research of M.A. was supported by a JAE-Predoc Research Grant from the Spanish National Research Council (Consejo Superior de Investigaciones Científicas; CSIC).Peer reviewe
Syntrophic degradation of fatty acids by methanogenic communities
In methanogenic environments degradation of fatty acids is a key process in the conversion of organic matter to methane and carbon dioxide. For degradation of fatty acids with three or more carbon atoms syntrophic communities are required. This chapter describes the general features of syntrophic degradation in methanogenic environments and the properties of the microorganisms involved. Syntrophic fatty acid-degrading communities grow at the minimum of what is thermodynamically possible and they employ biochemical mechanisms to share the minimum amount of chemical energy that is available. Aggregation of the syntrophic fatty acid-degrading communities is required for high rate conversion.(undefined
Complete genome sequence of Syntrophobacter fumaroxidans strain (MPOB(T)).
Syntrophobacter fumaroxidans strain MPOB(T) is the best-studied species of the genus Syntrophobacter. The species is of interest because of its anaerobic syntrophic lifestyle, its involvement in the conversion of propionate to acetate, H2 and CO2 during the overall degradation of organic matter, and its release of products that serve as substrates for other microorganisms. The strain is able to ferment fumarate in pure culture to CO2 and succinate, and is also able to grow as a sulfate reducer with propionate as an electron donor. This is the first complete genome sequence of a member of the genus Syntrophobacter and a member genus in the family Syntrophobacteraceae. Here we describe the features of this organism, together with the complete genome sequence and annotation. The 4,990,251 bp long genome with its 4,098 protein-coding and 81 RNA genes is a part of the Microbial Genome Program (MGP) and the Genomes to Life (GTL) Program project
Cost utility analysis of the SQ® HDM SLIT-tablet in house dust mite allergic asthma patients in a German setting
BACKGROUND: Asthma affects an estimated 300 million people worldwide with the condition associated with significant healthcare utilisation costs and a large impact on patient quality of life. The SQ(®) HDM SLIT-tablet (ACARIZAX(®), Hørsholm, Denmark) is a sublingually administered allergy immunotherapy tablet for house dust mite allergic asthma and allergic rhinitis and has recently been licensed in Europe. OBJECTIVE: To assess the cost-effectiveness of ACARIZAX plus pharmacotherapy versus placebo plus pharmacotherapy in patients with house dust mite allergic asthma that is uncontrolled by inhaled corticosteroids, in a German setting. Eligible patients should also have symptoms of mild to severe allergic rhinitis. METHODS: A cost utility analysis was undertaken, based on the results of a European phase III randomised controlled trial, in which ACARIZAX was compared with placebo with both treatment groups also receiving pharmacotherapy in the form of inhaled corticosteroids and short-acting β2-agonists. Cost and quality-adjusted life years from the trial were extrapolated over a nine year time horizon and the incremental cost-effectiveness ratio calculated to compare treatment options. RESULTS: ACARIZAX plus pharmacotherapy was estimated to generate 6.16 quality-adjusted life years per patient at a cost of €5658, compared with 5.50 quality-adjusted life years (QALYs) at a cost of €2985 for placebo plus pharmacotherapy. This equated to an incremental cost of €2673, incremental QALYs of 0.66 and an incremental cost-effectiveness ratio (ICER) of €4041. The ICER was, therefore, substantially lower than the €40,000 willingness-to-pay threshold per QALY adopted for the analysis. Deterministic sensitivity analyses indicate the results are most sensitive to the utility score of ACARIZAX patients during years 2 and 3 of treatment. CONCLUSION: This analysis indicates that ACARIZAX plus pharmacotherapy is cost-effective compared with placebo plus pharmacotherapy for house dust mite allergic asthma patients in Germany. If a disease-modifying effect can be proven the results of this analysis may underestimate the true benefits of ACARIZAX
Radiation Hardness Studies in a CCD with High-Speed Column Parallel Readout
Charge Coupled Devices (CCDs) have been successfully used in several high
energy physics experiments over the past two decades. Their high spatial
resolution and thin sensitive layers make them an excellent tool for studying
short-lived particles. The Linear Collider Flavour Identification (LCFI)
collaboration is developing Column-Parallel CCDs (CPCCDs) for the vertex
detector of the International Linear Collider (ILC). The CPCCDs can be read out
many times faster than standard CCDs, significantly increasing their operating
speed. The results of detailed simulations of the charge transfer inefficiency
(CTI) of a prototype CPCCD are reported and studies of the influence of gate
voltage on the CTI described. The effects of bulk radiation damage on the CTI
of a CPCCD are studied by simulating the effects of two electron trap levels,
0.17 and 0.44 eV, at different concentrations and operating temperatures. The
dependence of the CTI on different occupancy levels (percentage of hit pixels)
and readout frequencies is also studied. The optimal operating temperature for
the CPCCD, where the effects of the charge trapping are at a minimum, is found
to be about 230 K for the range of readout speeds proposed for the ILC. The
results of the full simulation have been compared with a simple analytic model.Comment: 3 pages, 6 figures; presented at IEEE'07, ALCPG'07, ICATPP'0
A Compact Beam Stop for a Rare Kaon Decay Experiment
We describe the development and testing of a novel beam stop for use in a
rare kaon decay experiment at the Brookhaven AGS. The beam stop is located
inside a dipole spectrometer magnet in close proximity to straw drift chambers
and intercepts a high-intensity neutral hadron beam. The design process,
involving both Monte Carlo simulations and beam tests of alternative beam-stop
shielding arrangements, had the goal of minimizing the leakage of particles
from the beam stop and the resulting hit rates in detectors, while preserving
maximum acceptance for events of interest. The beam tests consisted of
measurements of rates in drift chambers, scintilation counter hodoscopes, a gas
threshold Cherenkov counter, and a lead glass array. Measurements were also
made with a set of specialized detectors which were sensitive to low-energy
neutrons, photons, and charged particles. Comparisons are made between these
measurements and a detailed Monte Carlo simulation.Comment: 39 pages, 14 figures, submitted to Nuclear Instruments and Method
Drug induced modulation of T cell activation and differentiation in atopic dermatitis patients
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