Report of the US ITER Research Program Research Needs Workshop

The US ITER Research Program Basic Research Needs Workshop, held over the course of several months in 2022 with over 400 participants, sought to identify steps to be taken to both maximize the return of the US investment in ITER construction and operation and to ensure US research priorities on ITER strengthen the domestic program aimed at the development of a fusion pilot plant (FPP)

Public health performance strengthening at districts : rationale and blueprint for action : version 6.0

This white paper is drawn from conference proceedings in Bellagio (Italy) where experts in public health practice met to discuss strategies to help improve district level public health practice. Having countries decide on the essential public health functions for local health officers is the first step to developing measurements that can be used to help coach the workforce in supportive supervision. The Role of National Public Health Institutes in improving their public health workforce and strengthening public health practice is discussed. District health management personnel are government employees overseeing public health at a scale of roughly 100,000 people

Conjectures on Convergence and Scalar Curvature

Here we survey the compactness and geometric stability conjectures formulated by the participants at the 2018 IAS Emerging Topics Workshop on {\em Scalar Curvature and Convergence}. We have tried to survey all the progress towards these conjectures as well as related examples, although it is impossible to cover everything. We focus primarily on sequences of compact Riemannian manifolds with nonnegative scalar curvature and their limit spaces. Christina Sormani is grateful to have had the opportunity to write up our ideas and has done her best to credit everyone involved within the paper even though she is the only author listed above. In truth we are a team of over thirty people working together and apart on these deep questions and we welcome everyone who is interested in these conjectures to join us.Comment: Please email us any comments or corrections. 57 pages, 20 figures, IAS Emerging Topics on Scalar Curvature and Convergenc

Rifted Margins: State of the Art and Future Challenges

Improvements in seismic imaging, computing capabilities, and analytical methods, as well as a number of industry deep-water wells sampling distal offshore settings, have underpinned new concepts for rifted margin evolution developed in the last two decades; these mark significant progress in our understanding of extensional systems. For example, the tectonic, sedimentary, and magmatic processes linked to the formation of rifted margins have been overhauled, giving rise to more quantitative approaches and new concepts. However, these processes cannot be understood in isolation, requiring consideration of the continuum in which inheritance and physical processes are integrated within a plate tectonic framework. The major progress and fundamental developments of past research in rifted margins have been made hand-in-hand with other domains of Earth Sciences and have fundamental implications for the understanding of key geological systems such as active rifts, the ocean lithosphere, subduction zones, and collisional orogens. The “IMAGinING RIFTING” workshop, organized in Pontresina-Switzerland in September 2017, gathered researchers from all disciplines working on rifts and rifted margins, and included participants from academia and industry. This contribution summarizes the workshop discussions, in addition to outlining our state-of-the-art knowledge of rifted margins. We highlight future challenges in unraveling the processes and conditions under which these extensional systems form and, ultimately, how tectonic plates rupture and new oceans are born. Our aims here are to provide a framework for future research endeavors and to promote collaboration not only within the rift and rifted margins communities, but across other Earth Science disciplines

226th ENMC International Workshop: Towards validated and qualified biomarkers for therapy development for Duchenne muscular dystrophy 20-22 January 2017, Heemskerk, The Netherlands

Functional Genomics of Muscle, Nerve and Brain Disorder

Prevention and treatment of peri-implant diseases-The EFP S3 level clinical practice guideline.

BACKGROUND: The recently published Clinical Practice Guidelines (CPGs) for the treatment of stages I-IV periodontitis provided evidence-based recommendations for treating periodontitis patients, defined according to the 2018 classification. Peri-implant diseases were also re-defined in the 2018 classification. It is well established that both peri-implant mucositis and peri-implantitis are highly prevalent. In addition, peri-implantitis is particularly challenging to manage and is accompanied by significant morbidity. AIM: To develop an S3 level CPG for the prevention and treatment of peri-implant diseases, focusing on the implementation of interdisciplinary approaches required to prevent the development of peri-implant diseases or their recurrence, and to treat/rehabilitate patients with dental implants following the development of peri-implant diseases. MATERIALS AND METHODS: This S3 level CPG was developed by the European Federation of Periodontology, following methodological guidance from the Association of Scientific Medical Societies in Germany and the Grading of Recommendations Assessment, Development and Evaluation process. A rigorous and transparent process included synthesis of relevant research in 13 specifically commissioned systematic reviews, evaluation of the quality and strength of evidence, formulation of specific recommendations, and a structured consensus process involving leading experts and a broad base of stakeholders. RESULTS: The S3 level CPG for the prevention and treatment of peri-implant diseases culminated in the recommendation for implementation of various different interventions before, during and after implant placement/loading. Prevention of peri-implant diseases should commence when dental implants are planned, surgically placed and prosthetically loaded. Once the implants are loaded and in function, a supportive peri-implant care programme should be structured, including periodical assessment of peri-implant tissue health. If peri-implant mucositis or peri-implantitis are detected, appropriate treatments for their management must be rendered. CONCLUSION: The present S3 level CPG informs clinical practice, health systems, policymakers and, indirectly, the public on the available and most effective modalities to maintain healthy peri-implant tissues, and to manage peri-implant diseases, according to the available evidence at the time of publication