Integrating genomics for chickpea improvement: achievements and opportunities

The implementation of novel breeding technologies is expected to contribute substantial improvements in crop productivity. While conventional breeding methods have led to development of more than 200 improved chickpea varieties in the past, still there is ample scope to increase productivity. It is predicted that integration of modern genomic resources with conventional breeding efforts will help in the delivery of climate-resilient chickpea varieties in comparatively less time. Recent advances in genomics tools and technologies have facilitated the generation of large-scale sequencing and genotyping data sets in chickpea. Combined analysis of high-resolution phenotypic and genetic data is paving the way for identifying genes and biological pathways associated with breeding-related traits. Genomics technologies have been used to develop diagnostic markers for use in marker-assisted backcrossing programmes, which have yielded several molecular breeding products in chickpea. We anticipate that a sequence-based holistic breeding approach, including the integration of functional omics, parental selection, forward breeding and genome-wide selection, will bring a paradigm shift in development of superior chickpea varieties. There is a need to integrate the knowledge generated by modern genomics technologies with molecular breeding efforts to bridge the genome-to-phenome gap. Here, we review recent advances that have led to new possibilities for developing and screening breeding populations, and provide strategies for enhancing the selection efficiency and accelerating the rate of genetic gain in chickpea

Economic, environmental and social indicators of sustainability among smallholders in Ethiopia: Based on tool for agroecological performance evaluation data

This data article is a result of research conducted by a multidisciplinary team of researchers with the aim of analyzing agroecological transition and performance of agroecology in Ethiopia. It was conducted in four districts of Oromia and Southern Nations, Nationalities and People's (SNNP) regional states - Fedis district (East Hararghe Zone) and Miesso district (West Hararghe Zone) from the Oromia region, and Kindo Koysha district (Wolaita Zone) and Meskan district (Gurage Zone) of SNNP region. The rationale behind generating this dataset lies on the fact that there is scanty empirical evidence on the multidimensional performance of agroecology in the country. Available evidence only provides data on limited indicators of sustainability. Hence, there is a lack of comprehensive data on the economic, environmental and social indicators of sustainability and agroecological transition in the context of smallholder farming systems in the country. To fill this gap, the Food and Agriculture Organization of the United Nations (FAO) commissioned a consultancy project that employed the Tool for Agroecological Performance Evaluation (TAPE) to assess several dimensions and indicators of agroecological transitions and generate globally comparable data. A random sample of 619 farms were selected from 12 Kebeles (i.e., the lowest administrative unit), and trained enumerators gathered primary data based on a modified TAPE questionnaire using Kobo Toolbox. Participation of smallholders was on a voluntary basis and informed consent was obtained from the respondents. The survey questionnaire contained information on basic socio-economic and demographic characteristics, access to services and infrastructure, livelihood and Income-Generating Activities (IGAs), social and ecological indicators. Data on the 10 elements of agroecology was also collected. The collected data were entered into a STATA software, cleaned and analyzed through descriptive and inferential statistics. The outputs were summarized in Tables, Charts and Graphs. Since the data contained in this data article are disaggregated by study district, categories of agroecological transition, production typology and land size groups, this can foster the promotion of specific projects and programs that can address expressed needs of smallholder farmers. It can also facilitate agro-ecological based implementation of development interventions to encourage agroecological transition, sustainable development and food systems. The dataset can also enable researchers, practitioners and other decision-makers to make comparative analysis on the economic, environmental and social dimensions of sustainability. The analyzed data is provided in this data article. The raw data used to prepare figures is provided as a supplementary material. A copy of the questionnaire, raw dataset, and description of variables are available online on Mendeley Data

Global, regional, and national levels and causes of maternal mortality during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.

BACKGROUND The fifth Millennium Development Goal (MDG 5) established the goal of a 75% reduction in the maternal mortality ratio (MMR; number of maternal deaths per 100 000 livebirths) between 1990 and 2015. We aimed to measure levels and track trends in maternal mortality, the key causes contributing to maternal death, and timing of maternal death with respect to delivery. METHODS We used robust statistical methods including the Cause of Death Ensemble model (CODEm) to analyse a database of data for 7065 site-years and estimate the number of maternal deaths from all causes in 188 countries between 1990 and 2013. We estimated the number of pregnancy-related deaths caused by HIV on the basis of a systematic review of the relative risk of dying during pregnancy for HIV-positive women compared with HIV-negative women. We also estimated the fraction of these deaths aggravated by pregnancy on the basis of a systematic review. To estimate the numbers of maternal deaths due to nine different causes, we identified 61 sources from a systematic review and 943 site-years of vital registration data. We also did a systematic review of reports about the timing of maternal death, identifying 142 sources to use in our analysis. We developed estimates for each country for 1990-2013 using Bayesian meta-regression. We estimated 95% uncertainty intervals (UIs) for all values. FINDINGS 292 982 (95% UI 261 017-327 792) maternal deaths occurred in 2013, compared with 376 034 (343 483-407 574) in 1990. The global annual rate of change in the MMR was -0·3% (-1·1 to 0·6) from 1990 to 2003, and -2·7% (-3·9 to -1·5) from 2003 to 2013, with evidence of continued acceleration. MMRs reduced consistently in south, east, and southeast Asia between 1990 and 2013, but maternal deaths increased in much of sub-Saharan Africa during the 1990s. 2070 (1290-2866) maternal deaths were related to HIV in 2013, 0·4% (0·2-0·6) of the global total. MMR was highest in the oldest age groups in both 1990 and 2013. In 2013, most deaths occurred intrapartum or postpartum. Causes varied by region and between 1990 and 2013. We recorded substantial variation in the MMR by country in 2013, from 956·8 (685·1-1262·8) in South Sudan to 2·4 (1·6-3·6) in Iceland. INTERPRETATION Global rates of change suggest that only 16 countries will achieve the MDG 5 target by 2015. Accelerated reductions since the Millennium Declaration in 2000 coincide with increased development assistance for maternal, newborn, and child health. Setting of targets and associated interventions for after 2015 will need careful consideration of regions that are making slow progress, such as west and central Africa. FUNDING Bill & Melinda Gates Foundation