710 research outputs found
Recommended from our members
Patient-maintained propofol sedation for orthopaedic surgery: patient variability in system use
Recommended from our members
Finite element analysis of titanium alloy-graphene based mandible plate
Titanium alloy based maxillofacial plates and implants are widely used in fracture treatment and reconstructions. Filler materials Graphene Nanoplatlets(GNPs) were used in a Titanium alloy maxillofacial plate and a Finite Element Model (FEM) was designed to reconstruct a fractured human mandible. Both 50N and 500N bite forces were applied on the mandible and stress distribution using Von mises failure theory across the plate sections was analyzed. A pure plate was critically stressed at a section near the mandible fracture region for a Von mises stress of nearly 27.5GPa while this stress reduced by nearly 10–22% with the presence of minor composition of GNPs in the plate. GNPs orientation in parallel (21.1 GPa) to the plate axis were more effective in comparison to other orientations(90°, 45° and 135°) and the location variation of these GNPs along the plate had no significant effect on the stress distribution. The fatigue analyses showed that, under these stresses and forces the plate with GNP was able to endure for nearly 7000 days, while the pure Titanium plate could fail by fatigue in approximately 70 days. Hence, presence of minor compositions of GNPs could enhance endurance life of the Titanium plate by reducing stress concentrations at critical sections of the plate
OBSANP data acquisition system : operator's manual and system overview
On the Ocean Bottom Seismometer Augmentation in the North Pacific Experiment (OBSANP,
June-July, 2013, R/V Melville), a VLA and twelve OBSs were deployed to listen to an active
acoustic source, a J15-3. This report describes the hardware and software used to control and
record the acoustic transmissions from the source. Some significant features of the system are:
1) The system transmits general user-defined source functions, such as M-sequences (.SIO files).
2) In addition to controlling the source waveform, the system also records six real-time channels
in binary files with user-selectable lengths: the monitor hydrophone mounted near the source, the
power amplifier voltage and current, the depth of the source, Vref signal driving the power
amplifiers and an IRIG-B time reference. Files are output in .AUV format with a precision GPSbased
time stamp in the file name. 3) The transmission start time along with ADC and DAC
sample rates are disciplined to GPS time. 4) A convenient, Labview based, user interface
provides real-time source control and monitoring. 5) The software provides parsing and logging
of gyro and GPS NMEA sentences. The system, which was based on an earlier system from
Scripps MPL, worked well on OBSANP and is available for future projects.Funding was provided by the Office of Naval Research
under contract N00014-10-1-0987 and N00014-10-1-0510
Recommended from our members
Patient-maintained propofol sedation: the anaesthetists' point of view
Many operations within the UK do not require general anaesthesia, and are instead carried out under sedation. A doctor normally provides this, and as the patient is not in control, they may be either under or over-sedated due to a misjudgement of patient anxiety. One solution would be to allow the patients to directly control their own sedation level. This paper presents an invention for innovation (i4i) project developing such a Patient Maintained Propofol Sedation Device (PMPSD). Due to the health risks associated with under and over-sedation, the anaesthetists' interface takes on an added importance to ensure they can oversee the process and intervene when needed. Through the project, a unique opportunity has arisen where anaesthetists have been involved throughout the interface design process, contributing to the development and testing of a prototype. We present this prototype, highlight its key features and how it differs from existing sedation pump interface systems. As the project continues, the interface will be used as part of a clinical trial at Nottingham University Hospitals NHS Trust involving 80 orthopaedic patients throughout the rest of 2018 and into 2019
Recommended from our members
A prototype patient-maintained propofol sedation system using target controlled infusion for primary lower-limb arthroplasty
Each year, many operations in the UK are performed with the patient awake, without the use of general anaesthesia. These include joint replacement procedures, and in order to reduce patient anxiety, the supervising anaesthetist delivers the sedative propofol intravenously using a target-controlled infusion (TCI) device. However, it is clinically challenging to judge the required effect-site concentration of sedative for an individual patient, resulting in patient care issues related to over or under-sedation. To improve the process, patient-maintained propofol sedation (PMPS), where the patient can request an increase in concentration through a hand-held button, has been considered as an alternative. However, due to the proprietary nature of modern TCI pumps, the majority of PMPS research has been conducted using prototypes in research studies. In this work, a PMPS system is presented that effectively converts a standard infusion pump into a TCI device using a laptop with TCI software. Functionally, the system delivers sedation analogous to a modern TCI pump, with the differences in propofol consumption and dosage within the tolerance of clinically approved devices. Therefore, the Medicines and Healthcare products Regulatory Agency (MHRA) has approved the system as a safe alternative to anaesthetist-controlled TCI procedures. It represents a step forward in the consideration of PMPS as a sedation method as viable alternative, allowing further assessment in clinical trials
Recommended from our members
Low cost, user friendly embedded machine vision system implementation for high-speed industrial manufacture
The future of manufacturing environments is becoming increasingly intelligent. With Industry 4.0, and lean production strategies, many manufacturers are considering investing in intelligent, real time, and non-destructive machine vision (MV) systems for product manufacture fault analysis [2]. This technology is improving rapidly in both the industrial and consumer sectors [3]. This work presents the development of a low cost, user friendly embedded machine vision system for use in industrial snack manufacturing. Previous attempts at using a high cost ~£10000 system failed, due to inadequate knowledge for successful integration. The OpenMV cam M7 was procured as a low cost ~£100, simpler alternative. The system achieved 88% ±1% sensitivity and precision in detecting products on a live production line. Therefore this is a viable prototyping option for machine vision novices, enabling informed decisions thereafter
Ocean Bottom Seismometer Augmentation in the North Pacific (OBSANP) - cruise report
The Ocean Bottom Seismometer Augmentation in the North Pacific Experiment (OBSANP,
June-July, 2013, R/V Melville) addresses the coherence and depth dependence of deep-water
ambient noise and signals. During the 2004 NPAL Experiment in the North Pacific Ocean, in
addition to predicted ocean acoustic arrivals and deep shadow zone arrivals, we observed "deep
seafloor arrivals" (DSFA) that were dominant on the seafloor Ocean Bottom Seismometer (OBS)
(at about 5000m depth) but were absent or very weak on the Distributed Vertical Line Array
(DVLA) (above 4250m depth). At least a subset of these arrivals correspond to bottomdiffracted
surface-reflected (BDSR) paths from an out-of-plane seamount. BDSR arrivals are
present throughout the water column, but at depths above the conjugate depth are obscured by
ambient noise and PE predicted arrivals. On the 2004 NPAL/LOAPEX experiment BDSR paths
yielded the largest amplitude seafloor arrivals for ranges from 500 to 3200km. The OBSANP
experiment tests the hypothesis that BDSR paths contribute to the arrival structure on the deep
seafloor even at short ranges (from near zero to 4-1/2CZ). The OBSANP cruise had three major
research goals: a) identification and analysis of DSFA and BDSR arrivals occurring at short
(1/2CZ) ranges in the 50 to 400Hz band, b) analysis of deep sea ambient noise in the band 0.03
to 80Hz, and c) analysis of the frequency dependence of BR and SRBR paths. On OBSANP we
deployed a 32 element VLA from 12 to 1000m above the seafloor, eight short-period OBSs and
four long-period OBSs and carried out a 15day transmission program using a J15-3 acoustic
source.Funding was provided by the Office of Naval Research under contract #'s N00014-10-1-0987
and N00014-10-1-051
Search for the Rare Decays KL->pi0pi0mu+mu- and KL->pi0pi0X0->pi0pi0mu+mu-
The KTeV E799 experiment has conducted a search for the rare decays
KL->pi0pi0mu+mu- and KL->pi0pi0X0->pi0pi0mu+mu-, where the X0 is a possible new
neutral boson that was reported by the HyperCP experiment with a mass of (214.3
pm 0.5) MeV/c^{2}. We find no evidence for either decay. We obtain upper limits
of Br(KL->pi0pi0X0->pi0pi0mu+mu-) pi0pi0mu+mu-) <
9.2 x 10^{-11} at the 90% confidence level. This result rules out the
pseudoscalar X0 as an explanation of the HyperCP result under the scenario that
the \bar{d}sX0 coupling is completely real
Anthropology and GIS: Temporal and Spatial Distribution of the Philippine Negrito Groups
The Philippine negrito groups comprise a diverse group of populations speaking over 30 different languages, who are spread all over the archipelago, mostly in marginal areas of Luzon Island in the north, the central Visayas islands, and Mindanao in the south. They exhibit physical characteristics that are different from more than 100 Philippine ethnolinguistic groups that are categorized as non-negritos. Given their numbers, it is not surprising that Philippine negritos make up a major category in a number of general ethnographic maps produced since the nineteenth century. Reports from various ethnological surveys during this period, however, have further enriched our understanding regarding the extent and distribution of negrito populations. Using the data contained in these reports, it is possible to plot and create a map showing the historical locations and distribution of negrito groups. Using geographic information systems (GIS), the location and distribution of negrito groups at any given time can be overlaid on historical or current maps. In the present study, a GIS layer was compiled and extracted from the 2000 Philippine Census of population at the village level and overlaid on existing maps of the Philippines. The maps that were generated from this project will complement ongoing anthropological and genetic studies of negrito groups that inhabit different locations within the Philippine archipelago
Search for the Rare Decay K_{L}\to\pi^{0}\pi^{0}\gamma
The KTeV E799 experiment has conducted a search for the rare decay
via the topology
(where ). Due to Bose
statistics of the pair and the real nature of the photon, the
decay is restricted to proceed at lowest order
by the CP conserving direct emission (DE) of an E2 electric quadrupole photon.
The rate of this decay is interesting theoretically since chiral perturbation
theory predicts that this process vanishes at level . Therefore, this
mode probes chiral perturbation theory at . In this paper we report a
determination of an upper limit of (90% CL) for
. This is approximately a factor of 20 lower than
previous results.Comment: six pages and six figures in the submission. Reformatted for Physics
Review
- …