755 research outputs found
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Patient-maintained propofol sedation for orthopaedic surgery: patient variability in system use
Observations of sound-speed fluctuations in the Beaufort Sea from summer 2016 to summer 2017
© The Author(s), 2021. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Kucukosmanoglu, M., Colosi, J. A., Worcester, P. F., Dzieciuch, M. A., & Torres, D. J. Observations of sound-speed fluctuations in the Beaufort Sea from summer 2016 to summer 2017. Journal of the Acoustical Society of America, 149(3), (2021): 1536-1548, https://doi.org/10.1121/10.0003601.Due to seasonal ice cover, acoustics can provide a unique means for Arctic undersea communication, navigation, and remote sensing. This study seeks to quantify the annual cycle of the thermohaline structure in the Beaufort Sea and characterize acoustically relevant oceanographic processes such as eddies, internal waves, near-inertial waves (NIWs), and spice. The observations are from a seven-mooring, 150-km radius acoustic transceiver array equipped with oceanographic sensors that collected data in the Beaufort Sea from 2016 to 2017. Depth and time variations of the sound speed are analyzed using isopycnal displacements, allowing a separation of baroclinic processes and spice. Compared to lower latitudes, the overall sound speed variability is small with a maximum root mean square of 0.6 m/s. The largest source of variability is spice, most significant in the upper 100 m, followed by eddies and internal waves. The displacement spectrum in the internal wave band is time dependent and different from the Garret-Munk (GM) spectrum. The internal wave energy varied with time averaging 5% of the GM spectrum. The spice sound-speed frequency spectrum has a form very different from the displacement spectrum, a result not seen at lower latitudes. Because sound speed variations are weak, observations of episodic energetic NIWs with horizontal currents up to 20 cm/s have potential acoustical consequences.This research was supported by the Office of Naval Research (ONR) and M.K. was supported by an ONR Ocean Acoustics Graduate Student Fellowship under Award No. N00014-19-1-2203. The 600 kHz ADCP and IPS ice draft data were supported by the ONR Arctic and Global Prediction Program (ONR 322AG) under Award No. N00014-15-1-2782. This material is based on work supported by the ONR under Award No. N00014-15-2068
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Patient-maintained propofol sedation: the anaesthetists' point of view
Many operations within the UK do not require general anaesthesia, and are instead carried out under sedation. A doctor normally provides this, and as the patient is not in control, they may be either under or over-sedated due to a misjudgement of patient anxiety. One solution would be to allow the patients to directly control their own sedation level. This paper presents an invention for innovation (i4i) project developing such a Patient Maintained Propofol Sedation Device (PMPSD). Due to the health risks associated with under and over-sedation, the anaesthetists' interface takes on an added importance to ensure they can oversee the process and intervene when needed. Through the project, a unique opportunity has arisen where anaesthetists have been involved throughout the interface design process, contributing to the development and testing of a prototype. We present this prototype, highlight its key features and how it differs from existing sedation pump interface systems. As the project continues, the interface will be used as part of a clinical trial at Nottingham University Hospitals NHS Trust involving 80 orthopaedic patients throughout the rest of 2018 and into 2019
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Low cost, user friendly embedded machine vision system implementation for high-speed industrial manufacture
The future of manufacturing environments is becoming increasingly intelligent. With Industry 4.0, and lean production strategies, many manufacturers are considering investing in intelligent, real time, and non-destructive machine vision (MV) systems for product manufacture fault analysis [2]. This technology is improving rapidly in both the industrial and consumer sectors [3]. This work presents the development of a low cost, user friendly embedded machine vision system for use in industrial snack manufacturing. Previous attempts at using a high cost ~£10000 system failed, due to inadequate knowledge for successful integration. The OpenMV cam M7 was procured as a low cost ~£100, simpler alternative. The system achieved 88% ±1% sensitivity and precision in detecting products on a live production line. Therefore this is a viable prototyping option for machine vision novices, enabling informed decisions thereafter
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A prototype patient-maintained propofol sedation system using target controlled infusion for primary lower-limb arthroplasty
Each year, many operations in the UK are performed with the patient awake, without the use of general anaesthesia. These include joint replacement procedures, and in order to reduce patient anxiety, the supervising anaesthetist delivers the sedative propofol intravenously using a target-controlled infusion (TCI) device. However, it is clinically challenging to judge the required effect-site concentration of sedative for an individual patient, resulting in patient care issues related to over or under-sedation. To improve the process, patient-maintained propofol sedation (PMPS), where the patient can request an increase in concentration through a hand-held button, has been considered as an alternative. However, due to the proprietary nature of modern TCI pumps, the majority of PMPS research has been conducted using prototypes in research studies. In this work, a PMPS system is presented that effectively converts a standard infusion pump into a TCI device using a laptop with TCI software. Functionally, the system delivers sedation analogous to a modern TCI pump, with the differences in propofol consumption and dosage within the tolerance of clinically approved devices. Therefore, the Medicines and Healthcare products Regulatory Agency (MHRA) has approved the system as a safe alternative to anaesthetist-controlled TCI procedures. It represents a step forward in the consideration of PMPS as a sedation method as viable alternative, allowing further assessment in clinical trials
Polls and the political process: the use of opinion polls by political parties and mass media organizations in European post‐communist societies (1990–95)
Opinion polling occupies a significant role within the political process of most liberal-capitalist societies, where it is used by governments, parties and the mass media alike. This paper examines the extent to which polls are used for the same purposes in the post-communist countries of Central and Eastern Europe, and in particular, for bringing political elites and citizens together. It argues that these political elites are more concerned with using opinion polls for gaining competitive advantage over their rivals and for reaffirming their political power, than for devolving political power to citizens and improving the general processes of democratization
AND/R: Advanced neutron diffractometer/reflectometer for investigation of thin films and multilayers for the life sciences
An elastic neutron scattering instrument, the advanced neutron diffractometer/reflectometer (AND/R), has recently been commissioned at the National Institute of Standards and Technology Center for Neutron Research. The AND/R is the centerpiece of the Cold Neutrons for Biology and Technology partnership, which is dedicated to the structural characterization of thin films and multilayers of biological interest. The instrument is capable of measuring both specular and nonspecular reflectivity, as well as crystalline or semicrystalline diffraction at wave-vector transfers up to approximately 2.20 Å(-1). A detailed description of this flexible instrument and its performance characteristics in various operating modes are given.D. J. M. is supported
through a NSF NIRT grant Contract No. 0304062
Search for the Rare Decays KL->pi0pi0mu+mu- and KL->pi0pi0X0->pi0pi0mu+mu-
The KTeV E799 experiment has conducted a search for the rare decays
KL->pi0pi0mu+mu- and KL->pi0pi0X0->pi0pi0mu+mu-, where the X0 is a possible new
neutral boson that was reported by the HyperCP experiment with a mass of (214.3
pm 0.5) MeV/c^{2}. We find no evidence for either decay. We obtain upper limits
of Br(KL->pi0pi0X0->pi0pi0mu+mu-) pi0pi0mu+mu-) <
9.2 x 10^{-11} at the 90% confidence level. This result rules out the
pseudoscalar X0 as an explanation of the HyperCP result under the scenario that
the \bar{d}sX0 coupling is completely real
Search for the Rare Decay K_{L}\to\pi^{0}\pi^{0}\gamma
The KTeV E799 experiment has conducted a search for the rare decay
via the topology
(where ). Due to Bose
statistics of the pair and the real nature of the photon, the
decay is restricted to proceed at lowest order
by the CP conserving direct emission (DE) of an E2 electric quadrupole photon.
The rate of this decay is interesting theoretically since chiral perturbation
theory predicts that this process vanishes at level . Therefore, this
mode probes chiral perturbation theory at . In this paper we report a
determination of an upper limit of (90% CL) for
. This is approximately a factor of 20 lower than
previous results.Comment: six pages and six figures in the submission. Reformatted for Physics
Review
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