Scholastic Records and Personality and Character Traits of the Public-school Trained and the Parochial-trained Students of the Graduating Class of 1952, Central High School, Aberdeen, South Dakota

For many years at Aberdeen, South Dakota, a difference of opinion has existed regarding the relative academic achievement, rank in class, and social adjustments of the students in the public school system and parochial -school system. The advocates of the two school systems have base their opinions on observations only and without the benefit of statistical evidence. To present impartial evidence upon which the proponents may form a more logical conclusion was the purpose of the investigator. The purpose of this study was to compare the students who had received the first nine years of their training in a parochial school with those who had received their training in a public school to see if there were any statistical differences in their performance during the last three years of their high-school training in the public school. They were compared in mental ability, academic achievement, rank in class, and social ability development by the investigation cf the high school records of the graduating class of 1952. The school performances made by these students grouped into their respective origins were the records used in making the comparisons

Severity of depression and hypothalamic-pituitary-adrenal axis dysregulation: identification of contributing factors

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65507/1/j.1600-0447.1990.tb05465.x.pd

Randomized clinical trial of the effects of screening and brief intervention for illicit drug use: the Life Shift/Shift Gears study.

BackgroundAlthough screening, brief intervention, and referral to treatment (SBIRT) has shown promise for alcohol use, relatively little is known about its effectiveness for adult illicit drug use. This randomized controlled trial assessed the effectiveness of the SBIRT approach for outcomes related to drug use among patients visiting trauma and emergency departments (EDs) at two large, urban hospitals.MethodsA total of 700 ED patients who admitted using illegal drugs in the past 30 days were recruited, consented, provided baseline measures of substance use and related problems measured with the Addiction Severity Index-Lite (ASI-Lite), and then randomized to the Life Shift SBIRT intervention or to an attention-placebo control group focusing on driving and traffic safety (Shift Gears). Both groups received a level of motivational intervention matched to their condition and risk level by trained paraprofessional health educators. Separate measurement technicians conducted face-to-face follow-ups at 6 months post-intervention and collected hair samples to confirm reports of abstinence from drug use. The primary outcome measure of the study was past 30-day drug abstinence at 6 months post-intervention, as self-reported on the ASI-Lite.ResultsOf 700 participants, 292 (42%) completed follow-up. There were no significant differences in self-reported abstinence (12.5% vs. 12.0% , p = 0.88) for Life Shift and Shift Gears groups, respectively. When results of hair analyses were applied, the abstinence rate was 7 percent for Life Shift and 2 percent for Shift Gears (p = .074). In an analysis in which results were imputed (n = 694), there was no significant difference in the ASI-Lite drug use composite scores (Life Shift +0.005 vs. Shift Gears +0.017, p = 0.12).ConclusionsIn this randomized controlled trial, there was no evidence of effectiveness of SBIRT on the primary drug use outcome.Trial registrationClinicalTrials.gov NCT01683227

Report of the Secretary of War: Wagon Road Routes in Utah Territory

Report of the secretary of war, communicating, in compliance with a resolution of the Senate, Captain Simpson\u27s report and map of wagon road routes in Utah Territory

Stress, salt flux, and dynamics of a partially mixed estuary

A field study was performed in the lower Hudson River, a partially mixed estuary with a relatively simple geometry (Figure 1), between August and October of 1995. The objectives of the study were (1) to quantify and characterize the turbulent transport of momentum and salt, and (2) to relate the turbulent transport processes to the local and estuary-wide dynamics. The measurement program consisted of fixed and shipboard components. At a central site, a moored array of temperature-conductivity sensors and optical backscatter sensors (OBS), a bottom-mounted acoustic Doppler current profiler (ADCP), and a bottom-mounted array of acoustic travel-time current sensors (BASS), temperature-conductivity sensors, and OBS sensors resolved the vertical structure of velocity, salinity and turbidity and the near-bottom turbulence structure. Moored and bottom-mounted velocity, temperature, conductivity and pressure sensors at five secondary sites quantified the spatial and temporal variabilty of velocity, salinity and bottom pressure. Shipboard measurements with an ADCP and a conductivity-temperature-depth (CTD) profiler, accompanied by an OBS sensor, resolved the spatial structure and tidal variability of velocity, salinity and turbidity along several cross-channel and along-channel transects. This report describes the measurements in detail. Section II describes the instrumentation, Section III describes the deployment and sampling schemes, Section IV describes the data processing, and Section V is a summary of plots of selected data. Section VI documents the data files and Sections VII and VII give acknowledgments and references.Funding was provided by the National Science Foundation under Grant OCE-94-15617 and The Hudson River Foundation

Topological organization of whole-brain white matter in HIV infection

Infection with human immunodeficiency virus (HIV) is associated with neuroimaging alterations. However, little is known about the topological organization of whole-brain networks and the corresponding association with cognition. As such, we examined structural whole-brain white matter connectivity patterns and cognitive performance in 29 HIV+ young adults (mean age = 25.9) with limited or no HIV treatment history. HIV+ participants and demographically similar HIV− controls (n = 16) residing in South Africa underwent magnetic resonance imaging (MRI) and neuropsychological testing. Structural network models were constructed using diffusion MRI-based multifiber tractography and T(1)-weighted MRI-based regional gray matter segmentation. Global network measures included whole-brain structural integration, connection strength, and structural segregation. Cognition was measured using a neuropsychological global deficit score (GDS) as well as individual cognitive domains. Results revealed that HIV+ participants exhibited significant disruptions to whole-brain networks, characterized by weaker structural integration (characteristic path length and efficiency), connection strength, and structural segregation (clustering coefficient) than HIV− controls (p < 0.05). GDSs and performance on learning/recall tasks were negatively correlated with the clustering coefficient (p < 0.05) in HIV+ participants. Results from this study indicate disruption to brain network integrity in treatment-limited HIV+ young adults with corresponding abnormalities in cognitive performance

Cuprizone demyelination of the corpus callosum in mice correlates with altered social interaction and impaired bilateral sensorimotor coordination

For studies of remyelination in demyelinating diseases, the cuprizone model of CC (corpus callosum) demyelination has experimental advantages that include overall size, proximity to neural stem cells of the subventricular zone, and correlation with a lesion predilection site in multiple sclerosis. In addition, cuprizone treatment can be ended to allow more direct analysis of remyelination than with viral or autoimmune models. However, CC demyelination lacks a useful functional correlate in rodents for longitudinal analysis throughout the course of demyelination and remyelination. In the present study, we tested two distinct behavioural measurements in mice fed 0.2% cuprizone. Running on a ‘complex' wheel with varied rung intervals requires integration between cerebral hemispheres for rapid bilateral sensorimotor coordination. Maximum running velocity on the ‘complex' wheel decreased during acute (6 week) and chronic (12 week) cuprizone demyelination. Running velocity on the complex wheel distinguished treated (for 6 weeks) from non-treated mice, even after a 6-week recovery period for spontaneous remyelination. A second behavioural assessment was a resident–intruder test of social interaction. The frequency of interactive behaviours increased among resident mice after acute or chronic demyelination. Differences in both sensorimotor coordination and social interaction correlated with demonstrated CC demyelination. The wheel assay is applicable for longitudinal studies. The resident–intruder assay provides a complementary assessment of a distinct modality at a specific time point. These behavioural measurements are sufficiently robust for small cohorts as a non-invasive assessment of demyelination to facilitate analysis of subsequent remyelination. These measurements may also identify CC involvement in other mouse models of central nervous system injuries and disorders