A Comparison and Joint Analysis of Sunyaev-Zel'dovich Effect Measurements from Planck and Bolocam for a set of 47 Massive Galaxy Clusters

We measure the SZ signal toward a set of 47 clusters with a median mass of $9.5 \times 10^{14}$ M$_{\odot}$ and a median redshift of 0.40 using data from Planck and the ground-based Bolocam receiver. When Planck XMM-like masses are used to set the scale radius $\theta_{\textrm{s}}$, we find consistency between the integrated SZ signal, $Y_{\textrm{5R500}}$, derived from Bolocam and Planck based on gNFW model fits using A10 shape parameters, with an average ratio of $1.069 \pm 0.030$ (allowing for the $\simeq 5$% Bolocam flux calibration uncertainty). We also perform a joint fit to the Bolocam and Planck data using a modified A10 model with the outer logarithmic slope $\beta$ allowed to vary, finding $\beta = 6.13 \pm 0.16 \pm 0.76$ (measurement error followed by intrinsic scatter). In addition, we find that the value of $\beta$ scales with mass and redshift according to $\beta \propto M^{0.077 \pm 0.026} \times (1+z)^{-0.06 \pm 0.09}$. This mass scaling is in good agreement with recent simulations. We do not observe the strong trend of $\beta$ with redshift seen in simulations, though we conclude that this is most likely due to our sample selection. Finally, we use Bolocam measurements of $Y_{500}$ to test the accuracy of the Planck completeness estimate. We find consistency, with the actual number of Planck detections falling approximately $1 \sigma$ below the expectation from Bolocam. We translate this small difference into a constraint on the the effective mass bias for the Planck cluster cosmology results, with $(1-b) = 0.93 \pm 0.06$.Comment: Updated to include one additional co-author. Also some minor changes to the text based on initial feedbac

The efficacy of different vitamin D supplementation delivery methods on serum 25(OH)D: A randomised double-blind placebo trial

Background: The use of vitamin D supplementation has increased due to greater recognition of widespread deficiency. Aims: There has been little research on the effectiveness of different delivery methods and therefore the aim of was to test the efficacy of different delivery methods on serum 25(OH)D. Methods: Using a randomised repeated measures double-blind placebo design (registered under ClinicalTrials.gov Identifier no. NCT03463642), changes in serum 25(OH)D over a 4-week period using a capillary spot method were monitored. 62 female participants blindly chose a number related to a supplementation delivery method: pill placebo, pill, oral liquid, oral liquid placebo, Skin oil application (SOA) placebo, SOA plus vitamin D3 suspension, or SOA plus vitamin D3 suspension with essential oil enhancer; active vitamin D supplements contained 100,000IU. Participants took their allocated supplements over a 24-hr period with serum 25(OH)D retested 4 weeks later. Liquid chromatography-tandem mass spectrometry method was applied to dried blood spot samples by an independent laboratory. Results: ANCOVA reported a significant difference between the groups (F1,6 = 146.68; p < 0.001, eta2 = 0.51). Separate analysis within the delivery methods (pill, SOA, oral liquid) indicated significant differences between the active and placebo supplementation groups (p < 0.01). Post hoc analysis of absolute changes indicated vit D pill and SOA + vit D + essential oil had significant increases (p < 0.05) in serum 25(OH)D compared to all other interventions with no significant difference between them. Conclusions: In human participants vitamin D oral pill has the greatest effect on serum 25(OH)D levels. Skin oil application delivery of vitamin D using a penetrator enhancer has also been shown to be an effective method of delivery. © 2020 Elsevier Ltd and European Society for Clinical Nutrition and Metabolis

Association between Inflammation and Cardiac Geometry in Chronic Kidney Disease: Findings from the CRIC Study.

Background Left ventricular hypertrophy (LVH) and myocardial contractile dysfunction are independent predictors of mortality in patients with chronic kidney disease (CKD). The association between inflammatory biomarkers and cardiac geometry has not yet been studied in a large cohort of CKD patients with a wide range of kidney function. Methods Plasma levels of interleukin (IL)-1β, IL-1 receptor antagonist (IL-1RA), IL-6, tumor necrosis factor (TNF)-α, transforming growth factor (TGF)-β, high-sensitivity C-Reactive protein (hs-CRP), fibrinogen and serum albumin were measured in 3,939 Chronic Renal Insufficiency Cohort study participants. Echocardiography was performed according to the recommendations of the American Society of Echocardiography and interpreted at a centralized core laboratory. Results LVH, systolic dysfunction and diastolic dysfunction were present in 52.3%, 11.8% and 76.3% of the study subjects, respectively. In logistic regression analysis adjusted for age, sex, race/ethnicity, diabetic status, current smoking status, systolic blood pressure, urinary albumin- creatinine ratio and estimated glomerular filtration rate, hs-CRP (OR 1.26 [95% CI 1.16, 1.37], p Conclusion In patients with CKD, elevated plasma levels of hs-CRP and IL-6 are associated with LVH and systolic dysfunction

Beyond energy efficiency in evaluating sustainable development in planning and the built environment

The EU has set the policy target of reducing energy use by 20% by the year 2020. Therefore, a substantial consumption decrease is needed in the built environment sector. Despite the great energy efficiency improvements in households, recent energy consumption data analyses show that these targets will unlikely be reached. The general aim of this study is to point out the need to define new indicators and evaluation approaches in urban planning and the built environment which are based on the concept of ‘energy subsidiarity', focusing on local renewable resources rather than on current approaches based on energy efficiency. This concept correlates energy consumption with the energy supply from local renewable resources and is here proposed as the new urban planning evaluation approach toward a sustainable built environment. In the paper, the ‘Jevons Paradox' concept and the ‘energy rebound effect' phenomenon are used to demonstrate how current approaches based on energy efficiency, alone, cannot lead to a remarkable reduction of energy consumption. This is also supported by data on European energy consumption and European energy efficiency in the built environment. Finally, a number of well-known European ecological districts (‘eco-districts') are analysed in terms of sustainable energy strategy as well as energy efficiency and energy balance. This study shows that there is a contradiction between the purpose of some of the eco-districts to be low consumption (or low impacts), and the district renewable energy balance. Only a few of the analysed eco-districts are able to cover energy needs by using renewable energy obtained in the surrounding area. In most of the cases, the focus of the districts' activities is on energy efficiency. According to the ‘Jevons Paradox' and ‘energy rebound effect' paradigm, energy efficiency alone will unlikely lead to an effective reduction in resources' consumption. These results point out the need for a radical shift toward the development of new approaches in the assessment and management of the built environment for sustainabilit

A Comparison and Joint Analysis of Sunyaev-Zel'dovich Effect Measurements from Planck and Bolocam for a set of 47 Massive Galaxy Clusters

We measure the Sunyaev–Zel'dovich (SZ) signal toward a set of 47 clusters with a median mass of 9.5 × 10^(14) M_☉ and a median redshift of 0.40 using data from Planck and the ground-based Bolocam receiver. When Planck XMM-like masses are used to set the scale radius θ_s, we find consistency between the integrated SZ signal, Y_(5R500), derived from Bolocam and Planck based on generalized Navarro, Frenk, and White model fits using A10 shape parameters, with an average ratio of 1.069 ± 0.030 (allowing for the ≃ 5% Bolocam flux calibration uncertainty). We also perform a joint fit to the Bolocam and Planck data using a modified A10 model with the outer logarithmic slope β allowed to vary, finding β = 6.13 ± 0.16 ± 0.76 (measurement error followed by intrinsic scatter). In addition, we find that the value of β scales with mass and redshift according to β ∝ M^(0.077 ± 0.026) x (1 + z))^(-0.06 ± 0.09). This mass scaling is in good agreement with recent simulations. We do not observe the strong trend of β with redshift seen in simulations, though we conclude that this is most likely due to our sample selection. Finally, we use Bolocam measurements of Y 500 to test the accuracy of the Planck completeness estimate. We find consistency, with the actual number of Planck detections falling approximately 1σ below the expectation from Bolocam. We translate this small difference into a constraint on the effective mass bias for the Planck cluster cosmology results, with (1 - b)=0.93 ± 0.06

Modern cities modelled as “super-cells” rather than multicellular organisms: Implications for industry, goods and services

The structure and “metabolism” (movement and conversion of goods and energy) of urban areas has caused cities to be identified as “super-organisms”, placed between ecosystems and the biosphere, in the hierarchy of living systems. Yet most such analogies are weak, and render the super-organism model ineffective for sustainable development of cities. Via a cluster analysis of 15 shared traits of the hierarchical living system, we found that industrialized cities are more similar to eukaryotic cells than to multicellular organisms; enclosed systems, such as factories and greenhouses, paralleling organelles in eukaryotic cells. We further developed a “super-cell” industrialized city model: a “eukarcity” with citynucleus (urban area) as a regulating centre, and organaras (enclosed systems, which provide the majority of goods and services) as the functional components, and cityplasm (natural ecosystems and farmlands) as the matrix. This model may improve the vitality and sustainability of cities through planning and management

Peer expectations about outstanding competencies of men and women medical students

Men and women enrolled in a combined premedical-medical school programme were asked as they began their clinical training to rate their anticipated competence on sixteen criteria relevant to medical practice. Competence dimensions tapped scientific/technical skills, dedication/commitment, and interpersonal skills. Students then were asked to nominate one classmate whom they expected might be‘the best’in each area. Self-ratings revealed few differences among men and women. Peer nominations, however, revealed a preponderance of male nominees in ten competence areas. Women dominated nominations only in the category of sensitivity to patients. Patterns persisted when peer nominations were controlled for students’academic standing and self-ratings on parallel dimensions. The data suggest that medical school peer groups share expectations about competencies of men and women as physicians which are consistent with generalized sex stereotypes and career patterns of men and women physicians.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/74843/1/1467-9566.ep11340055.pd