The Study of Indian Raids In Northwest Kansas, 1864-1878

For the purposes of this study, Northwest Kansas is defined as that area lying to the north and west of Saline County , Kansas. The area is bounded on the south by the northern boundaries of McPherson, Rice, Barton, Rush , Ness, Lane; Scott, Wichita and Greeley Counties . On the east it is bounded by the western boundaries of Dickinson , Clay, and Washington Counties. The area is bounded on the west by Colorado and on the north by Nebraska. One Indian battle described in the study, that of Forsyth\u27s command on the Arickaree, occurred outside the defined area. This battle is included because of its close relation to the Indian difficulties in Northwest Kansas

Consumer-based actions to reduce plastic pollution in rivers: a multi-criteria decision analysis approach

The use and management of single use plastics is a major area of concern for the public, regulatory and business worlds. Focusing on the most commonly occurring consumer plastic items present in European freshwater environments, we identified and evaluated consumer-based actions with respect to their direct or indirect potential to reduce macroplastic pollution in freshwater environments. As the main end users of these items, concerned consumers are faced with a bewildering array of choices to reduce their plastics footprint, notably through recycling or using reusable items. Using a Multi-Criteria Decision Analysis approach, we explored the effectiveness of 27 plastic reduction actions with respect to their feasibility, economic impacts, environmental impacts, unintended social/environmental impacts, potential scale of change and evidence of impact. The top ranked consumer-based actions were identified as: using wooden or reusable cutlery; switching to reusable water bottles; using wooden or reusable stirrers; using plastic free cotton-buds; and using refill detergent/ shampoo bottles. We examined the feasibility of top-ranked actions using a SWOT analysis (Strengths, Weaknesses, Opportunities and Threats) to explore the complexities inherent in their implementation for consumers, businesses, and government to reduce the presence of plastic in the environment

MARIA M4:clinical evaluation of a prototype ultrawideband radar scanner for breast cancer detection

A microwave imaging system has been developed as a clinical diagnostic tool operating in the 3- to 8-GHz region using multistatic data collection. A total of 86 patients recruited from a symptomatic breast care clinic were scanned with a prototype design. The resultant three-dimensional images have been compared “blind” with available ultrasound and mammogram images to determine the detection rate. Images show the location of the strongest signal, and this corresponded in both older and younger women, with sensitivity of [Formula: see text] , which was found to be maintained in dense breasts. The pathway from clinical prototype to clinical evaluation is outlined

A mechanism for the Arctic sea ice spring predictability barrier

The decline of Arctic sea ice extent has created a pressing need for accurate seasonal predictions of regional summer sea ice. Recent work has shown evidence for an Arctic sea ice spring predictability barrier, which may impose a sharp limit on regional forecasts initialized prior to spring. However, the physical mechanism for this barrier has remained elusive. In this work, we perform a daily sea ice mass (SIM) budget analysis in large ensemble experiments from two global climate models to investigate the mechanisms that underpin the spring predictability barrier. We find that predictability is limited in winter months by synoptically driven SIM export and negative feedbacks from sea ice growth. The spring barrier results from a sharp increase in predictability at melt onset, when ice‐albedo feedbacks act to enhance and persist the preexisting export‐generated mass anomaly. These results imply that ice thickness observations collected after melt onset are particularly critical for summer Arctic sea ice predictions

A mechanism for the Arctic sea ice spring predictability barrier

The decline of Arctic sea ice extent has created a pressing need for accurate seasonal predictions of regional summer sea ice. Recent work has shown evidence for an Arctic sea ice spring predictability barrier, which may impose a sharp limit on regional forecasts initialized prior to spring. However, the physical mechanism for this barrier has remained elusive. In this work, we perform a daily sea ice mass (SIM) budget analysis in large ensemble experiments from two global climate models to investigate the mechanisms that underpin the spring predictability barrier. We find that predictability is limited in winter months by synoptically driven SIM export and negative feedbacks from sea ice growth. The spring barrier results from a sharp increase in predictability at melt onset, when ice‐albedo feedbacks act to enhance and persist the preexisting export‐generated mass anomaly. These results imply that ice thickness observations collected after melt onset are particularly critical for summer Arctic sea ice predictions

Single-cell lineage tracing in the mammary gland reveals stochastic clonal dispersion of stem/progenitor cell progeny.

The mammary gland undergoes cycles of growth and regeneration throughout reproductive life, a process that requires mammary stem cells (MaSCs). Whilst recent genetic fate-mapping studies using lineage-specific promoters have provided valuable insights into the mammary epithelial hierarchy, the true differentiation potential of adult MaSCs remains unclear. To address this, herein we utilize a stochastic genetic-labelling strategy to indelibly mark a single cell and its progeny in situ, combined with tissue clearing and 3D imaging. Using this approach, clones arising from a single parent cell could be visualized in their entirety. We reveal that clonal progeny contribute exclusively to either luminal or basal lineages and are distributed sporadically to branching ducts or alveoli. Quantitative analyses suggest that pools of unipotent stem/progenitor cells contribute to adult mammary gland development. Our results highlight the utility of tracing a single cell and reveal that progeny of a single proliferative MaSC/progenitor are dispersed throughout the epithelium.This work was supported by a grant from the Medical Research Council programme grant no. MR/J001023/1 (B.L-L. and C.J.W). F.M.D. was funded by a National Health and Medical Research Council CJ Martin Biomedical Fellowship (GNT1071074). O.B.H. was funded by a Wellcome Trust PhD studentship (105377/Z/14/Z)

Potential drivers of virulence evolution in aquaculture

Infectious diseases are economically detrimental to aquaculture, and with continued expansion and intensification of aquaculture, the importance of managing infectious diseases will likely increase in the future. Here, we use evolution of virulence theory, along with examples, to identify aquaculture practices that might lead to the evolution of increased pathogen virulence. We identify eight practices common in aquaculture that theory predicts may favor evolution toward higher pathogen virulence. Four are related to intensive aquaculture operations, and four others are related specifically to infectious disease control. Our intention is to make aquaculture managers aware of these risks, such that with increased vigilance, they might be able to detect and prevent the emergence and spread of increasingly troublesome pathogen strains in the future

An absorbing boundary formulation for the stratified, linearized, ideal MHD equations based on an unsplit, convolutional perfectly matched layer

Perfectly matched layers are a very efficient and accurate way to absorb waves in media. We present a stable convolutional unsplit perfectly matched formulation designed for the linearized stratified Euler equations. However, the technique as applied to the Magneto-hydrodynamic (MHD) equations requires the use of a sponge, which, despite placing the perfectly matched status in question, is still highly efficient at absorbing outgoing waves. We study solutions of the equations in the backdrop of models of linearized wave propagation in the Sun. We test the numerical stability of the schemes by integrating the equations over a large number of wave periods.Comment: 8 pages, 7 figures, accepted, A &