Contaminants in Unionid Mussels from the Confluence of the Mississippi and Illinois Rivers

Unionid mussels were collected from three mussel beds near the confluence of the Mississippi and Illinois rivers in 2003 to evaluate concentrations of selected elements and organic compounds in three abundant species and to preliminarily investigate the relative contribution of these waterways to observed contaminant burdens. Copper (Cu), selenium (Se), and zinc (Zn) concentrations were higher and lead (Pb) concentrations were lower in Amblema plicata collected downstream of the confluence than in those collected upstream. Mean concentrations of nickel (Ni), total mercury (Hg), methylmercury (MeHg), Pb, and Zn varied by species. Concentrations of cadmium (Cd) decreased with age in A. plicata from two of three sites. Tissue concentrations of some elements, e.g., arsenic (As), Cd, Cu, Pb, Se, and Zn, were similar to or higher than those previously reported for unionid mussels from areas of contaminated sediment. Concentrations of Cd, Cu, and Zn in A. plicata were comparable to those collected from the Mississippi River approximately 450 and 900 km upstream from our study sites (Naimo et al. 1992). Although total Hg concentrations we observed were an order of magnitude lower than in that study, MeHg concentrations were above those associated with reductions in soft tissue mass in a study of Elliptio complanata (Salazar et al. 1995). A number of polychlorinated biphenyl (PCB) congeners were detected in A. plicata tissues, with 85% of detections occurring in mussels from downstream of the confluence. Concentrations of individual PCB congeners were ???33 ng/g ww and the maximum summed PCB congener concentration was 100.2 ng/g ww. Although few persistent pesticides were detected, -hexachlorocyclohexane (HCH) was detected in each of the species collected from below the confluence of the two rivers, and in A. plicata collected above it on both the Mississippi and Illinois rivers, at a maximum concentration of 103.5 ng/g ww. Aldrin, ??-HCH and dichlorodiphenyltrichloroethane (DDT) were detected in few of the specimens collected. The findings of this preliminary investigation suggest that unionid mussels from near the confluence of the Mississippi and Illinois rivers may be at risk of negative health effects of elevated exposure to certain environmental contaminants. Studies examining the health and productivity of unionid mussels from this area appear warranted.published or submitted for publicationis peer reviewe

Fine particle separation in a riser with flow modifications

Fine particle separation is of great interest in industry. Coal and mineral processing industries are currently very interested in particle separation for its potential in cleaning coal matter. A circulating fluidized bed riser system has been constructed to investigate possible separation of coal containing pyrite from clean coal. The system was constructed to operate using compressed air in which an air-solid mixture would pass through the riser and the solids would enter in to a dense, product, or filter collection bin. Several different variables were investigated during the project such as the collection ring wall height, particle entrance size into the riser, and mass flux of particles into the riser. By changing the particle entrance into the riser, and changing the ratio of nozzle flow and particle mass flux, a jet style flow could be achieved. The objective of this investigation was to observe how changing the flow field in a circulating fluidized bed would affect particle separation.;The first experiment was conducted using a mixture of sand and steel shot with particles sizes between 250 and 500 micron. Results from using the sand and steel shot proved to be very promising as more than 90% of the steel shot could be collected from the sand. The results were then used to determine the experimental conditions that were to be used while separating pyrite laden coal particles from clean coal. There was approximately 1% initial pyrite in the mixture and size ranges for the particles were between 105 and 210 micron. The results using the run-of-mine coal were not as promising as those of the sand and steel shot as a maximum of 25% of the pyritic laden coal could be separated from the cleaner coal. A third experiment was then performed in which chunks of pure pyrite were crushed and then added into clean coal and run through similar separation conditions to the run-of-mine coal. The mixture contained 4% pyrite, and both the pure pyrite and clean coal size ranges were between 105 and 210 micron. The results from this test proved to be very good as up to 77% of the pure pyrite could be recovered from the clean coal

Contaminants in Unionid Mussels from the Confluence of the Mississippi and Illinois Rivers

Unionid mussels were collected from three mussel beds near the confluence of the Mississippi and Illinois rivers in 2003 to evaluate concentrations of selected elements and organic compounds in three abundant species and to preliminarily investigate the relative contribution of these waterways to observed contaminant burdens. Copper (Cu), selenium (Se), and zinc (Zn) concentrations were higher and lead (Pb) concentrations were lower in Amblema plicata collected downstream of the confluence than in those collected upstream. Mean concentrations of nickel (Ni), total mercury (Hg), methylmercury (MeHg), Pb, and Zn varied by species. Concentrations of cadmium (Cd) decreased with age in A. plicata from two of three sites. Tissue concentrations of some elements, e.g., arsenic (As), Cd, Cu, Pb, Se, and Zn, were similar to or higher than those previously reported for unionid mussels from areas of contaminated sediment. Concentrations of Cd, Cu, and Zn in A. plicata were comparable to those collected from the Mississippi River approximately 450 and 900 km upstream from our study sites (Naimo et al. 1992). Although total Hg concentrations we observed were an order of magnitude lower than in that study, MeHg concentrations were above those associated with reductions in soft tissue mass in a study of Elliptio complanata (Salazar et al. 1995). A number of polychlorinated biphenyl (PCB) congeners were detected in A. plicata tissues, with 85% of detections occurring in mussels from downstream of the confluence. Concentrations of individual PCB congeners were ≤33 ng/g ww and the maximum summed PCB congener concentration was 100.2 ng/g ww. Although few persistent pesticides were detected, -hexachlorocyclohexane (HCH) was detected in each of the species collected from below the confluence of the two rivers, and in A. plicata collected above it on both the Mississippi and Illinois rivers, at a maximum concentration of 103.5 ng/g ww. Aldrin, δ-HCH and dichlorodiphenyltrichloroethane (DDT) were detected in few of the specimens collected. The findings of this preliminary investigation suggest that unionid mussels from near the confluence of the Mississippi and Illinois rivers may be at risk of negative health effects of elevated exposure to certain environmental contaminants. Studies examining the health and productivity of unionid mussels from this area appear warranted

The influence of a virtual companion on amusement when watching funny films

We investigated the role of a virtual companion and trait cheerfulness on the elicitation of amusement. Ninety participants watched funny films in four conditions: either alone, with a virtual companion laughing or verbally expressing amusement at fixed time points (pre-scripted), or additionally joining the participant’s laughter (responsive companion). Amusement was assessed facially and vocally by coding Duchenne Displays and laughter vocalizations. Participants’ cheerful mood pre and post the film watching and positive experience were assessed. Results showed that high trait cheerful individuals generally experienced and expressed more amusement than low trait cheerful individuals. The presence of a virtual companion (compared to being alone) led to more laughter for individuals low in trait cheerfulness. Unexpectedly, the responsive companion did not elicit more amusement than the pre-scripted companion. The general disliking of virtual companions and gelotophobia related negatively to amusement. Amusement expressing virtual companions may be used in interventions aiming at eliciting positive responses, especially for individuals with higher thresholds for amusement.European Union Seventh Framework Programme (FP7/2007-2013) under Grant Agreement No. 27078

SUNDIALS Time Integrators for Exascale Applications with Many Independent ODE Systems

Many complex systems can be accurately modeled as a set of coupled time-dependent partial differential equations (PDEs). However, solving such equations can be prohibitively expensive, easily taxing the world's largest supercomputers. One pragmatic strategy for attacking such problems is to split the PDEs into components that can more easily be solved in isolation. This operator splitting approach is used ubiquitously across scientific domains, and in many cases leads to a set of ordinary differential equations (ODEs) that need to be solved as part of a larger "outer-loop" time-stepping approach. The SUNDIALS library provides a plethora of robust time integration algorithms for solving ODEs, and the U.S. Department of Energy Exascale Computing Project (ECP) has supported its extension to applications on exascale-capable computing hardware. In this paper, we highlight some SUNDIALS capabilities and its deployment in combustion and cosmology application codes (Pele and Nyx, respectively) where operator splitting gives rise to numerous, small ODE systems that must be solved concurrently

Demographic Differences in Patterns of Youth Out-of-School Time Activity Participation

Participation in structured out-of-school time (OST) activities is of growing interest to families, youth practitioners, and policymakers. OST activities benefit youth socially, emotionally, and academically, especially at-risk youth. Yet, little research has explored the characteristics of youth participants. This study examines whether demographic differences exist merely in getting youth “in the door” of activities, or whether differences persist when examining the number of activities and the amount of time youth spend in activities once they are there. Results from two nationally representative datasets showed that disadvantaged youth were less likely to participate in a variety of activities than their peers, and participated in fewer numbers of activities. Among youth who did participate, Blacks and Hispanics participated less frequently in some activities, although Blacks participated more frequently in community-based youth programs. Implications for recruitment and retention are discussed, including the need for activity leaders to enhance efforts to attract and sustain disadvantaged and ethnic minority youth

SUNDIALS time integrators for exascale applications with many independent systems of ordinary differential equations

Many complex systems can be accurately modeled as a set of coupled time-dependent partial differential equations (PDEs). However, solving such equations can be prohibitively expensive, easily taxing the world’s largest supercomputers. One pragmatic strategy for attacking such problems is to split the PDEs into components that can more easily be solved in isolation. This operator splitting approach is used ubiquitously across scientific domains, and in many cases leads to a set of ordinary differential equations (ODEs) that need to be solved as part of a larger “outer-loop” time-stepping approach. The SUNDIALS library provides a plethora of robust time integration algorithms for solving ODEs, and the U.S. Department of Energy Exascale Computing Project (ECP) has supported its extension to applications on exascale-capable computing hardware. In this paper, we highlight some SUNDIALS capabilities and its deployment in combustion and cosmology application codes (Pele and Nyx, respectively) where operator splitting gives rise to numerous, small ODE systems that must be solved concurrently

Role of PHOSPHO1 in periodontal development and function

The tooth root and periodontal apparatus, including the acellular and cellular cementum, periodontal ligament (PDL), and alveolar bone, are critical for tooth function. Cementum and bone mineralization is regulated by factors including enzymes and extracellular matrix proteins that promote or inhibit hydroxyapatite crystal growth. Orphan Phosphatase 1 (Phospho1, PHOSPHO1) is a phosphatase expressed by chondrocytes, osteoblasts, and odontoblasts that functions in skeletal and dentin mineralization by initiating deposition of hydroxyapatite inside membrane-limited matrix vesicles. The role of PHOSPHO1 in periodontal formation remains unknown and we aimed to determine its functional importance in these tissues. We hypothesized that the enzyme would regulate proper mineralization of the periodontal apparatus. Spatiotemporal expression of PHOSPHO1 was mapped during periodontal development, and Phospho1(-/-) mice were analyzed using histology, immunohistochemistry, in situ hybridization, radiography, and micro–computed tomography. The Phospho1 gene and PHOSPHO1 protein were expressed by active alveolar bone osteoblasts and cementoblasts during cellular cementum formation. In Phospho1(-/-) mice, acellular cementum formation and mineralization were unaffected, whereas cellular cementum deposition increased although it displayed delayed mineralization and cementoid. Phospho1(-/-) mice featured disturbances in alveolar bone mineralization, shown by accumulation of unmineralized osteoid matrix and interglobular patterns of protein deposition. Parallel to other skeletal sites, deposition of mineral-regulating protein osteopontin (OPN) was increased in alveolar bone in Phospho1(-/-) mice. In contrast to the skeleton, genetic ablation of Spp1, the gene encoding OPN, did not ameliorate dentoalveolar defects in Phospho1(-/-) mice. Despite alveolar bone mineralization defects, periodontal attachment and function appeared undisturbed in Phospho1(-/-) mice, with normal PDL architecture and no evidence of bone loss over time. This study highlights the role of PHOSPHO1 in mineralization of alveolar bone and cellular cementum, further revealing that acellular cementum formation is not substantially regulated by PHOSPHO1 and likely does not rely on matrix vesicle–mediated initiation of mineralization