4,174 research outputs found

    Structural Changes in the Iranian Economy: An Empirical Analysis with Endogenously Determined Breaks

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    This paper employs annual time series data (1960-2003) and the ZA (Zivot and Andrews, 1992) and the LP (Lumsdaine and Papell, 1997) approaches to determine endogenously the more likely time of major structural breaks in various macroeconomic variables of the Iranian economy. We have considered the presence of one and two unknown structural breaks in the data. The results obtained from these two approaches are consistent in that the time of one structural break in eight out of the ten variables examined in the paper is the same. The resulting structural breaks coincide with important phenomena in the economy such as the 1974 oil shock, the 1979 Islamic revolution, the Iraqi war or the implementation of the exchange rate unification policy in 1993 in the case of the official exchange rate.structural break, unit root test, Iranian economy

    A Primer for Work-Based Learning: How to Make a Job the Basis for a College Education

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    Provides an overview of the Jobs to Careers model, in which employers and colleges collaborate to embed curricula and training in the work process, as a way to meet healthcare labor force needs. Includes grantee profiles, lessons learned, and worksheets

    Effects of methamphetamine abuse and serotonin transporter gene variants on aggression and emotion-processing neurocircuitry.

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    Individuals who abuse methamphetamine (MA) exhibit heightened aggression, but the neurobiological underpinnings are poorly understood. As variability in the serotonin transporter (SERT) gene can influence aggression, this study assessed possible contributions of this gene to MA-related aggression. In all, 53 MA-dependent and 47 control participants provided self-reports of aggression, and underwent functional magnetic resonance imaging while viewing pictures of faces. Participants were genotyped at two functional polymorphic loci in the SERT gene: the SERT-linked polymorphic region (SERT-LPR) and the intron 2 variable number tandem repeat polymorphism (STin2 VNTR); participants were then classified as having high or low risk for aggression according to individual SERT risk allele combinations. Comparison of SERT risk allele loads between groups showed no difference between MA-dependent and control participants. Comparison of self-report scores showed greater aggression in MA-dependent than control participants, and in high genetic risk than low-risk participants. Signal change in the amygdala was lower in high genetic risk than low-risk participants, but showed no main effect of MA abuse; however, signal change correlated negatively with MA use measures. Whole-brain differences in activation were observed between MA-dependent and control groups in the occipital and prefrontal cortex, and between genetic high- and low-risk groups in the occipital, fusiform, supramarginal and prefrontal cortex, with effects overlapping in a small region in the right ventrolateral prefrontal cortex. The findings suggest that the investigated SERT risk allele loads are comparable between MA-dependent and healthy individuals, and that MA and genetic risk influence aggression independently, with minimal overlap in associated neural substrates

    Structural breaks, unit roots and postwar slowdowns in Iranian economy

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    This paper employs annual time series data (1970-2003) using Perron (1997) approaches to determine endogenously the more likely time of major structural breaks in various macroeconomic variables of the Iranian economy

    Manejo del cáncer en atención primaria

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    408 p. : il.; gráf. , 22 cm.Libro ElectrónicoÍNDICE Índice de Autores Agradecimientos Prólogo La Oncología y el papel de A.Pen la prevención y seguimiento tumoral Félix Zubiri, Jesús Honorato y Wilson Astudillo Importancia de los programas de diagnóstico rápido en el cáncer de mama y colon Javier Zubeldia La Genética en el cáncer Iñaki Gutiérrez Iy Eunate Arana A Manifestaciones externas de las enfermedades oncológicas Anna Tuneu Vals y Arantxa López Pestaña Cáncer y sistema nerviosoTumores cerebrales primitivos y complicaciones neurológicas del cáncer Miguel AUrtasun Ocariz y José Félix Martí Massó Cáncer de pulmónPrevención, diagnóstico y tratamiento Yolanda Vilches A Novedades en el diagnóstico y tratamiento del cáncer de mama José Antonio Alberro Aduriz. Utilización de nanopartículas metálicas en el tratamiento de cánceres localizados Javier Aizpurua Iriazabal Cáncer de estómago y de intestino grueso: prevención y tratamiento Enrique Ojembarrena Martínez Posibilidades y límites de la cirugía en los tumores abdominales Adolfo Beguiristain Gómez El Hospital de Día y la hospitalización domiciliaria en el tratamiento onco- lógico y la paliación María Dolores De Damborenea González Tratamiento del dolor oncológico intenso Antonio Pernia Ry Luis Miguel Torres M. El cáncer en el niñoRealidad actual y expectativas Itziar Astigarraga Aguirre El niño con cáncer y los supervivientesLa superación de una nueva oportunidad Aurora Navajas Gutiérrez Organización de una unidad de Cuidados Paliativos pediátricos en la Comunidad de Madrid Ricardo Martino Alba, Ana Robles TElena Catá del Palacio, Carola del Rincón F El cáncer en el ancianoCaracterísticas y necesidades especiales Juan Carlos Caballero G. Necesidades emocionales en el paciente con cáncer Carmen Yélamos Ay Belén F Curados de cáncerLa superación y una nueva oportunidadLa necesidad de unidades especiales de apoyo Carmen Yélamos Ay José Samblas G El apoyo al cuidador del enfermo oncológico Wilson Astudillo A., Carmen Mendinueta Ay Beatriz Astudillo Ly Belén Díaz-Albo B Cuidados Paliativos en África Antonio Salinas-Martín y Emilio Montiano La limitación del esfuerzo terapéutico Carlos Romeo Casabona ¿Qué hacer cuando la curación no es posible? Papel de los Cuidados Paliativos Elías Díaz-Albo H., Belén Díaz-Albo B., Carmen Mendinueta Ay Wilson Astudillo A. Esperanza y dignidad en el paciente oncológico Koldo Martinez Urionabarrenetxea Sobre la felicidad y el sufrimiento Ramón Bayés Sopena Perspectiva de la OMS para el desarrollo de Cuidados Paliativos en el contexto de programa de control de cáncer en países en vías de desarrollo Cecilia Sepúlveda Bermedo Derechos de los cuidadores Derechos de un enfermo en el final de la vida Índice de materia

    EVIDENCE-SCIENTIFIC TESTS FOR lNTOXICATION-ADMISSIBILITY

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    It is the purpose of this comment to examine the admissibility and probative value of the tests available for determining the amount of alcohol in the human system

    My Indian Maiden

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    https://digitalcommons.library.umaine.edu/mmb-vp/4010/thumbnail.jp

    Proceedings 2013: Selected papers from the seventeenth college-wide conference for students in languages, linguistics & literature

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    Selected papers from the seventeenth annual college-wide conference for students in languages, linguistics & literature, at the University of Hawai`i at MānoaSelected papers from the seventeenth annual college-wide conference for students in languages, linguistics & literature, at the University of Hawai`i at MānoaCollege of Languages, Linguistics & Literature, University of Hawai‘

    Non-invasive molecular imaging of inflammatory macrophages in allograft rejection.

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    BackgroundMacrophages represent a critical cell type in host defense, development and homeostasis. The ability to image non-invasively pro-inflammatory macrophage infiltrate into a transplanted organ may provide an additional tool for the monitoring of the immune response of the recipient against the donor graft. We therefore decided to image in vivo sialoadhesin (Sn, Siglec 1 or CD169) using anti-Sn mAb (SER-4) directly radiolabelled with (99m)Tc pertechnetate.MethodsWe used a heterotopic heart transplantation model where allogeneic or syngeneic heart grafts were transplanted into the abdomen of recipients. In vivo nanosingle-photon emission computed tomography (SPECT/CT) imaging was performed 7 days post transplantation followed by biodistribution and histology.ResultsIn wild-type mice, the majority of (99m)Tc-SER-4 monoclonal antibody cleared from the blood with a half-life of 167 min and was located predominantly on Sn(+) tissues in the spleen, liver and bone marrow. The biodistribution in the transplantation experiments confirmed data derived from the non-invasive SPECT/CT images, with significantly higher levels of (99m)Tc-SER-4 observed in allogeneic grafts (9.4 (±2.7) %ID/g) compared to syngeneic grafts (4.3 (±10.3) %ID/g) (p = 0.0022) or in mice which received allogeneic grafts injected with (99m)Tc-IgG isotype control (5.9 (±0.6) %ID/g) (p = 0.0185). The transplanted heart to blood ratio was also significantly higher in recipients with allogeneic grafts receiving (99m)Tc-SER-4 as compared to recipients with syngeneic grafts (p = 0.000004) or recipients with allogeneic grafts receiving (99m)Tc-IgG isotype (p = 0.000002).ConclusionsHere, we demonstrate that imaging of Sn(+) macrophages in inflammation may provide an important additional and non-invasive tool for the monitoring of the pathophysiology of cellular immunity in a transplant model
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