2,628 research outputs found

    An overview of the marine fish landings in Andhra Pradesh during 2014

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    The estimated marine fish landings in Andhra Pradesh during the year 2014 was 3.41 lakh tonnes (t) as compared to 2.66 lakh t in 2013 showing an increase of 28%. The state’s contribution to the all India landings during 2014 was 9.5 %. Resources such as Indian mackerel and lesser sardines constituted the maximum, being 16.3% and 12.2% of the landings respectively. Tunnies and penaeid prawns landings contributed 8% each while the other important species/ groups were ribbon fishes 5.9%, carangids 5.5%, perches 4.2%, croakers 3.8%, oil sardine 3.5%, goatfishes 2.3%, seer fishes 2.3%, Stolephorus spp. 2%, crabs 2%, Silverbellies 1.9% and elasmobranchs 1.6%. Landings of crabs, Indian mackerel, oil sardine, lesser sardines, seer fishes and tunnies had increased by 0.4, 0.65, 1.04, 2.32, 0.56, 1.07 times respectively when compared to 2013 landing trends. Other clupeids and silverbellies had decreased when compared to the previous year landings

    A simple Bayesian estimate of direct RNAi gene regulation events from differential gene expression profiles.

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    RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are.BACKGROUND: Microarrays are commonly used to investigate both the therapeutic potential and functional effects of RNA interfering (RNAi) oligonucleotides such as microRNA (miRNA) and small interfering RNA (siRNA). However, the resulting datasets are often challenging to interpret as they include extensive information relating to both indirect transcription effects and off-target interference events. METHOD: In an attempt to refine the utility of microarray expression data when evaluating the direct transcriptional affects of an RNAi agent we have developed SBSE (Simple Bayesian Seed Estimate). The key assumption implemented in SBSE is that both direct regulation of transcription by miRNA, and siRNA off-target interference, can be estimated using the differential distribution of an RNAi sequence (seed) motif in a ranked 3' untranslated region (3' UTR) sequence repository. SBSE uses common microarray summary statistics (i.e. fold change) and a simple Bayesian analysis to estimate how the RNAi agent dictated the observed differential expression profile. On completion a trace of the estimate and the location of the optimal partitioning of the dataset are plotted within a simple graphical representation of the 3'UTR landscape. The combined estimates define the differential distribution of the query motif within the dataset and by inference are used to quantify the magnitude of the direct RNAi transcription effect. RESULTS: SBSE has been evaluated using five diverse human RNAi microarray focused investigations. In each instance SBSE unambiguously identified the most likely location of the direct RNAi effects for each of the differential gene expression profiles. CONCLUSION: These analyses indicate that miRNA with conserved seed regions may share minimal biological activity and that SBSE can be used to differentiate siRNAs of similar efficacy but with different off-target signalling potential.Peer Reviewe

    Six different football shoes, one playing surface and the weather; Assessing variation in shoe-surface traction over one season of elite football

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    <div><p>Introduction</p><p>An optimal range of shoe-surface traction (grip) exists to improve performance and minimise injury risk. Little information exists regarding the magnitude of traction forces at shoe-surface interface across a full season of elite football (soccer) using common football shoes.</p><p>Objective</p><p>To assess variation in shoe-surface traction of six different football shoe models throughout a full playing season in Qatar encompassing climatic and grass species variations.</p><p>Methods</p><p>Football shoes were loaded onto a portable shoe-surface traction testing machine at five individual testing time points to collect traction data (rotational and translational) on a soccer playing surface across one season. Surface mechanical properties (surface hardness, soil moisture) and climate data (temperature and humidity) were collected at each testing time point.</p><p>Results</p><p>Peak rotational traction was significantly different across shoe models (F = 218, df = 5, p <0.0001), shoe outsole groups (F = 316.2, df = 2, p < .0001), and grass species (F = 202.8, df = 4, p < 0.0001). No main effect for shoe model was found for translational traction (F = 2.392, p = 0.07).</p><p>Conclusions</p><p>The rotational (but not translational) traction varied substantially across different shoe types, outsole groups, and grass species. Highest rotational traction values were seen with soft ground outsole (screw-in metal studs) shoes tested on warm season grass. This objective data allows more informed footwear choices for football played in warm/hot climates on sand-based elite football playing surfaces. Further research is required to confirm if these findings extend across other football shoe brands.</p></div

    Marine fish landings in Andhra Pradesh during 2015-an overview

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    Andhra Pradesh with a coastline of 974 km and spread over nine districts supports a rich marine fishery constituted by several groups of fishes, crustaceans and molluscs. About 1.5 lakh fishermen are directly or indirectly involved in the marine fisheries sector

    Indian marine fishery resources: optimistic present, challenging future

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    Marine fish production from capture fisheries in India has increased by about six fold during the past six decades. Export earnings from the marine sector crossed 12,000 crores in 2010-11 and gross revenue through marine fish landings at the point of first sales was about 20,000 crores. Marine products are now exported from India to nearly 100 countries. Monitoring the harvest of different marine fishery resources is very much essential for planning and implementing policies for sustained production from the sea. The dynamic changes in the landings of marine fishery resources over the last six decades were examined after classifying them into 26 different resource groups. Decadal averages of landings of different resource groups were compared using Student’s t test and coefficient of variation was worked out for each decade. Present status of each resource group was examined separately based on a simple criterion. Out of the 26 groups examined, 18 were found to be under the ‘abundant class, 5 under ‘less abundant’ class and one each under ‘declining’, ‘depleted’ and ‘collapsed’ classes. Elasmobranchs, threadfins, ribbonfishes, mullets and flatfishes are the five resource groups falling under ‘less abundant’ class. White fish falls under ‘declining’ class, flying fishes under ‘depleted’ class and unicorn cod under ‘collapsed’ class. All the other groups fall under the ‘abundant’ class indicating that most of the resources (73%) are in healthy condition. The ‘depleted’ and ‘collapsed’ classes require management interventions for the recovery of the resources and the group falling under ‘declining’ class needs caution and care to prevent further reduction in the stock

    Overview of the marine fish landings in Andhra Pradesh during 2012

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    Andhra Pradesh, with 974 km of coastline and continental shelf area forming 31,000 sq. km, is rich with many species of prawns, carangids, Perches, croakers and elasmobranchs. During 2012, the estimated marine fish landing of Andhra Pradesh was 3.04 lakh t

    Debate:Challenges in sports cardiology; US versus European approaches

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    For practitioners working with elite athletes, the field of sports cardiology provides clinical, academic, administrative and fiscal challenges. These challenges are exemplified and reinforced by the lack of consistency and consensus both in the literature and academic presentations. Through thepresentation of a series of clinical questions, this debate attempts to ‘cut to the chase’ on cardiovascular issues relevant to the clinician dealing with elite athletes. In so doing, we hope to crystallize some of the most important elements of the complex cardiological management of elite athletes, in a concise, readable format. Frequently over the last 10 years, many of the controversies in this field have been (rightly or wrongly) presented in aEurope versus USA paradigm. We have chosen to test whether there really are polarised views across the Atlantic, by deliberately pitting specialists from the USA against those from the UK. Professors Levine and Thompson are both internationally recognised sports cardiologists, with immense academic and clinical credibility, and who will represent the ‘US approach’. Professor Whyte and Doctor Wilson are cardiac physiologists with a wealth of experience in the testing, evaluation and screening of elite athletes, and who have equally impressive academic credibility and for the purposes of this debate, they will be representing the ‘European approach’. To initiate this process, each team was required to provide a concise answer (circa 200–300 words) to a series of fiveclinical conundrums. Subsequently, each team had the opportunity to provide a rebuttal to the opposing team’s answers, and the following reflects the consolidation of those answers

    Systematic review and evidence appraisal of objectively assessed longitudinal changes in moderate-to-vigorous physical activity among children and adolescents (2-18 years old)

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    The aim of this study was to systematically review accelerometer based longitudinal studies which have quantified year to year changes in moderate-to-vigorous physical activity (MVPA) among the general paediatric population in the absence of any intervention

    Hypertrophic cardiomyopathy and ultra-endurance running - two incompatible entities?

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    Regular and prolonged exercise is associated with increased left ventricular wall thickness that can overlap with hypertrophic cardiomyopathy (HCM). Differentiating physiological from pathological hypertrophy has important implications, since HCM is the commonest cause of exercise-related sudden cardiac death in young individuals. Most deaths have been reported in intermittent 'start-stop' sports such as football (soccer) and basketball. The theory is that individuals with HCM are unable to augment stroke volume sufficiently to meet the demands of endurance sports and are accordingly 'selected-out' of participation in such events. We report the case of an ultra-endurance athlete with 25 years of > 50 km competitive running experience, with genetically confirmed HCM; thereby demonstrating that these can be two compatible entities

    Longitudinal changes in moderate-to-vigorous-intensity physical activity in children and adolescents: a systematic review and meta-analysis

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    Moderate‐to‐vigorous‐intensity physical activity (MVPA) is important for childhood obesity prevention and treatment, yet declines with age. Timing and magnitude of the decline in MVPA in children and adolescents are unclear but important for informing effective obesity intervention development. This systematic review aimed to determine and compare the year‐to‐year changes in MVPA among children and adolescents. Longitudinal studies were identified by searching 10 relevant databases up to December 2018. Studies were eligible for inclusion if they reported accelerometer‐assessed MVPA (min day−1) separately for boys and girls and had follow‐up duration of at least 1 year. After screening 9,232 studies, 52 were included representing 22,091 aged 3 to 18 year olds (boys=8,857; girls=13,234). Pooled‐analysis of the relative change in MVPA per year showed a decline of −3.4% (95% CI, −5.9 to −0.9) in boys and −5.3% (95% CI, −7.6 to −3.1) in girls, across all age groups. There were notable declines in MVPA at age 9 for both boys (−7.8%, 95% CI, −11.2 to −4.4) and girls (−10.2%, 95% CI, −14.2 to −6.3). The relative decline in MVPA affects both sexes from an early age; however, it is greater among girls. Interventions to promote MVPA should start before adolescence
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