5,318 research outputs found

    A Hotel for Independence Center, A Mixed-Use Facility for Charlotte, N.C.

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    Progress in Lunar Laser Ranging Tests of Relativistic Gravity

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    Analyses of laser ranges to the Moon provide increasingly stringent limits on any violation of the Equivalence Principle (EP); they also enable several very accurate tests of relativistic gravity. We report the results of our recent analysis of Lunar Laser Ranging (LLR) data giving an EP test of \Delta (M_G/M_I)_{EP} =(-1.0 +/- 1.4) x 10^{-13}. This result yields a Strong Equivalence Principle (SEP) test of \Delta (M_G/M_I)_{SEP} =(-2.0 +/- 2.0) x 10^{-13}. Also, the corresponding SEP violation parameter \eta is (4.4 +/- 4.5) x 10^{-4}, where \eta=4\beta-\gamma-3 and both \beta and \gamma are parametrized post-Newtonian (PPN) parameters. Using the recent Cassini result for the parameter \gamma, PPN parameter \beta is determined to be \beta-1=(1.2 +/- 1.1) x 10^{-4}. The geodetic precession test, expressed as a relative deviation from general relativity, is K_{gp}=-0.0019 +/- 0.0064. The search for a time variation in the gravitational constant results in \dot G/G=(4 +/- 9) x 10^{-13} yr^{-1}, consequently there is no evidence for local (~1AU) scale expansion of the solar system.Comment: 4 pages, revtex4, minor changes made for publicatio

    Solar system constraints on the Dvali-Gabadadze-Porrati braneworld theory of gravity

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    A number of proposals have been put forward to account for the observed accelerating expansion of the Universe through modifications of gravity. One specific scenario, Dvali-Gabadadze-Porrati (DGP) gravity, gives rise to a potentially observable anomaly in the solar system: all planets would exhibit a common anomalous precession, dw/dt, in excess of the prediction of General Relativity. We have used the Planetary Ephemeris Program (PEP) along with planetary radar and radio tracking data to set a constraint of |dw/dt| < 0.02 arcseconds per century on the presence of any such common precession. This sensitivity falls short of that needed to detect the estimated universal precession of |dw/dt| = 5e-4 arcseconds per century expected in the DGP scenario. We discuss the fact that ranging data between objects that orbit in a common plane cannot constrain the DGP scenario. It is only through the relative inclinations of the planetary orbital planes that solar system ranging data have sensitivity to the DGP-like effect of universal precession. In addition, we illustrate the importance of performing a numerical evaluation of the sensitivity of the data set and model to any perturbative precession.Comment: 9 pages, 2 figures, accepted for publication in Phys. Rev.

    Biopsy proven medullary sponge kidney: clinical findings, histopathology, and role of osteogenesis in stone and plaque formation

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    Medullary sponge kidney (MSK) is associated with recurrent stone formation, but the clinical phenotype is unclear because patients with other disorders may be incorrectly labeled MSK. We studied 12 patients with histologic findings pathognomonic of MSK. All patients had an endoscopically recognizable pattern of papillary malformation, which may be segmental or diffuse. Affected papillae are enlarged and billowy, due to markedly enlarged inner medullary collecting ducts (IMCD), which contain small, mobile ductal stones. Patients had frequent dilation of Bellini ducts, with occasional mineral plugs. Stones may form over white (Randall's) plaque, but most renal pelvic stones are not attached, and have a similar morphology as ductal stones, which are a mixture of calcium oxalate and apatite. Patients had no abnormalities of urinary acidification or acid excretion; the most frequent metabolic abnormality was idiopathic hypercalciuria. Although both Runx2 and Osterix are expressed in papillae of MSK patients, no mineral deposition was seen at the sites of gene expression, arguing against a role of these genes in this process. Similar studies in idiopathic calcium stone formers showed no expression of these genes at sites of Randall's plaque. The most likely mechanism for stone formation in MSK appears to be crystallization due to urinary stasis in dilated IMCD with subsequent passage of ductal stones into the renal pelvis where they may serve as nuclei for stone formation

    Mini-mast CSI testbed user's guide

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    The Mini-Mast testbed is a 20 m generic truss highly representative of future deployable trusses for space applications. It is fully instrumented for system identification and active vibrations control experiments and is used as a ground testbed at NASA-Langley. The facility has actuators and feedback sensors linked via fiber optic cables to the Advanced Real Time Simulation (ARTS) system, where user defined control laws are incorporated into generic controls software. The object of the facility is to conduct comprehensive active vibration control experiments on a dynamically realistic large space structure. A primary goal is to understand the practical effects of simplifying theoretical assumptions. This User's Guide describes the hardware and its primary components, the dynamic characteristics of the test article, the control law implementation process, and the necessary safeguards employed to protect the test article. Suggestions for a strawman controls experiment are also included

    A Proposed Grading System to Standardize the Description of Renal Papillary Appearance at the Time of Endoscopy in Patients with Nephrolithiasis

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    BACKGROUND AND PURPOSE: The appearance of the renal papillae in patients with nephrolithiasis can be quite variable and can range from entirely healthy to markedly diseased. The implications of such findings remain unknown. One potential reason is the lack of a standardized system to describe such features. We propose a novel grading scale to describe papillary appearance at the time of renal endoscopy. METHODS: Comprehensive endoscopic renal assessment and mapping were performed on more than 300 patients with nephrolithiasis. Recurring abnormal papillary characteristics were identified and quantified based on degree of severity. RESULTS: Four unique papillary features were chosen for inclusion in the PPLA scoring system- ductal Plugging, Pitting, Loss of contour, and Amount of Randall's plaque. Unique scores are calculated for individual papillae based on reference examples. CONCLUSIONS: The description and study of renal papillary appearance in stone formers have considerable potential as both a clinical and research tool; however, a standardized grading system is necessary before using it for these purpos

    Papillary Ductal Plugging Is a Mechanism for Early Stone Retention in Brushite Stone Disease

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    Purpose Mechanisms of early stone retention in the kidney are under studied and poorly understood. To date attachment via Randall plaque is the only widely accepted theory in this regard, which is best described in idiopathic calcium oxalate stone formers. Brushite stone formers are known to have distinct papillary morphology relative to calcium oxalate stone formers. As such we sought to determine whether stone attachment mechanisms in such patients may be similarly unique. Materials and Methods Patients undergoing percutaneous and or ureteroscopic procedures for stone removal consented to endoscopic renal papillary examination and individual stone collection. Each removed stone was processed using micro computerized tomography to assess the 3-dimensional microstructure and the minerals contained, and search for common structural features indicative of novel mechanisms of early growth and attachment to renal tissue. Results A total of 25 intact brushite stones were removed from 8 patients and analyzed. Video confirmed attachment of 13 of the 25 stones with the remainder believed to have been accidently dislodged during the procedure. Microscopic examination by light and computerized tomography failed to show evidence of Randall plaque associated with any stone containing brushite. Conversely each brushite stone demonstrated microstructural evidence of having grown attached to a ductal plug formed of apatite. Conclusions Three-dimensional analysis of small brushite stones suggests overgrowth on ductal apatite plugs as a mechanism of early stone growth and retention. Such findings represent what is to our knowledge the initial supporting evidence for a novel mechanism of stone formation which has previously been hypothesized but never verified

    Near-field investigation of ions emitted from a hollow cathode assembly operating at low-power

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76514/1/AIAA-1998-3658-652.pd

    Advocating Affordable Housing in New Hampshire: The Amicus Curiae Brief of the American Planning Association in Wayne Britton v. Town of Chester

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    In June 1990, The American Planning Association, a national Washington, D.C. based non-profit association of 27,000 professional planners, elected and appointed planning officials, and citizens interested in improving urban and rural planning filed this amicus curiae brief with the New Hampshire Supreme Court. The case on appeal is Wayne Britton v. Town of Chester, No. 85-E-342 (N.H. Super. Ct. June 27, 1989), brought by a builder/developer and low-income plaintiffs in need of affordable housing in Chester, New Hampshire
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