4,778 research outputs found
Alien Registration- Wood, William M. (Orono, Penobscot County)
https://digitalmaine.com/alien_docs/5793/thumbnail.jp
Virtual Reality for Preservation: Production of Virtual Reality Heritage Spaces in the Classrooom
The Bethel AME Church was the oldest African American church in Indianapolis. In November 2016, the congregation moved out of downtown, and the building that had housed the congregation since 1869 was sold. It is now being redeveloped into a hotel. Through the Virtual Bethel project, faculty and students in the Media Arts and Science (MAS) program at Indiana University–Purdue University Indianapolis (IUPUI) created a 3D virtual space of the physical sanctuary to preserve the cultural heritage of Bethel. During its creation, Virtual Bethel served as a curricular and co-curricular experience for the undergraduate students in the 3D graphics and animation specialization within class N441 3D Team Production, which was co-taught by Albert William and Zebulun Wood. Virtual Bethel, finished in 2018, was the first historical and cultural preservation project that used VR within our class, program, school, and Indiana University (IU) campus. Users can interact with various types of primary sources (e.g., photographs, video, audio, text) to learn about the underrepresented history of African Americans associated with the church. Virtual Bethel was created in a series of classes within the MAS Program in the School of Informatics and Computing (SoIC), IUPUI. Methods of teaching a team of students to preserve historic spaces using VR are discussed, as are our philosophies toward productions when working with varying stakeholders’ priorities related to data preservation, asset preservation, and cultural preservation
Resistance to Fracture of Two All-Ceramic Crown Materials Following Endodontic Access
Statement of problem
There is currently no protocol for managing endodontic access openings for all-ceramic crowns. A direct restorative material is generally used to repair the access opening, rendering a repaired crown as the definitive restoration. This endodontic procedure, however, may weaken the restoration or initiate microcracks that may propagate, resulting in premature failure of the restoration. Purpose
The purpose of this in vitro study was to evaluate how an endodontic access opening prepared through an all-ceramic crown altered the structural integrity of the ceramic, and the effect of a repair of this access on the load to failure of an all-ceramic crown. Material and methods
Twenty-four alumina (Procera) and 24 zirconia (Procera) crowns were fabricated and cemented (Rely X Luting Plus Cement) onto duplicate epoxy resin dies. Twelve crowns of each were accessed to simulate root canal treatment therapy. Surface defects of all accessed specimens were evaluated with an environmental scanning electron microscope. The specimens were repaired with a porcelain repair system (standard adhesive resin/composite resin protocol) and were loaded to failure in a universal testing machine. Observations made visually and microscopically noted veneer delamination from the core, core fracture, shear within the veneer porcelain, or a combination thereof. A Kruskal-Wallis test was used to determine if a significant difference (α=.05) in load to failure existed between the 4 groups, and a Mann-Whitney test with a Bonferroni correction (P Results
All specimens exhibited edge chipping around the access openings. Some displayed larger chips within the veneering porcelain, and 4 zirconia crowns showed radial crack formation. There was a significant difference in load to failure among all groups with the exception of the alumina intact and repaired specimens (P=.695). The alumina crowns generally showed fracture of the coping with the veneering porcelain still bonded to the core, whereas the zirconia copings tended not to fracture but experienced veneering porcelain delamination. Conclusion
Endodontic access through all-ceramic crowns resulted in a significant loss of strength in the zirconia specimens but not in the alumina specimens
Reply to: O'Neill, H.S., 2021: “Comment on ‘Compositional and temperature effects on sulfur speciation and solubility in silicate melts’ ” by Nash et al. [Earth Planet. Sci. Lett. 507 (2019) 187–198]
Advancing Scientific Discourse in the Controversy Surrounding the Comprehensive System for the Rorschach: A Rejoinder to Meyer (2000)
A recent commentary by Meyer (2000) in the Journal of Personality Assessment alleged that Rorschach critic Wood and his colleagues had intentionally published information that they knew to be in error. To substantiate this contention, Meyer’s commentary published information that was part of the peer review process at another journal. In this rejoinder, we present factual information that shows we have consistently acted in good faith. This rejoinder suggests that the scientific debate regarding the Comprehensive System for the Rorschach is unlikely to be advanced by speculating about the intentions of Rorschach critics, or by publishing information from the peer review process that is usually kept confidential
MyoD-expressing progenitors are essential for skeletal myogenesis and satellite cell development
AbstractSkeletal myogenesis in the embryo is regulated by the coordinated expression of the MyoD family of muscle regulatory factors (MRFs). MyoD and Myf-5, which are the primary muscle lineage-determining factors, function in a partially redundant manner to establish muscle progenitor cell identity. Previous diphtheria toxin (DTA)-mediated ablation studies showed that MyoD+ progenitors rescue myogenesis in embryos in which Myf-5-expressing cells were targeted for ablation, raising the possibility that the regulative behavior of distinct, MRF-expressing populations explains the functional compensatory activities of these MRFs. Using MyoDiCre mice, we show that DTA-mediated ablation of MyoD-expressing cells results in the cessation of myogenesis by embryonic day 12.5 (E12.5), as assayed by myosin heavy chain (MyHC) and Myogenin staining. Importantly, MyoDiCre/+;R26DTA/+ embryos exhibited a concomitant loss of Myf-5+ progenitors, indicating that the vast majority of Myf-5+ progenitors express MyoD, a conclusion consistent with immunofluorescence analysis of Myf-5 protein expression in MyoDiCre lineage-labeled embryos. Surprisingly, staining for the paired box transcription factor, Pax7, which functions genetically upstream of MyoD in the trunk and is a marker for fetal myoblasts and satellite cell progenitors, was also lost by E12.5. Specific ablation of differentiating skeletal muscle in ACTA1Cre;R26DTA/+ embryos resulted in comparatively minor effects on MyoD+, Myf-5+ and Pax7+ progenitors, indicating that cell non-autonomous effects are unlikely to explain the rapid loss of myogenic progenitors in MyoDiCre/+;R26DTA/+ embryos. We conclude that the vast majority of myogenic cells transit through a MyoD+ state, and that MyoD+ progenitors are essential for myogenesis and stem cell development
Diffractive arrays of gold nanoparticles near an interface: critical role of the substrate
The optical properties of periodic arrays of plasmonic nanoantennas are
strongly affected by coherent multiple scattering in the plane of the array,
which leads to sharp spectral resonances in both transmission and reflection
when the wavelength is commensurate with the period. We demonstrate that the
presence of a substrate (i.e., an asymmetric refractive-index environment) can
inhibit long-range coupling between the particles and suppress lattice
resonances, in agreement with recent experimental results. We find the
substrate-to-superstrate index contrast and the distance between the array and
the interface to be critical parameters determining the strength of diffractive
coupling. Our rigorous electromagnetic simulations are well reproduced by a
simple analytical model. These findings are important in the design of periodic
structures and in the assessment of their optical resonances for potential use
in sensing and other photonic technologies
The emergence of <i>Pax7</i>-expressing muscle stem cells during vertebrate head muscle development
Pax7 expressing muscle stem cells accompany all skeletal muscles in the body and in healthy individuals, efficiently repair muscle after injury. Currently, the in vitro manipulation and culture of these cells is still in its infancy, yet muscle stem cells may be the most promising route towards the therapy of muscle diseases such as muscular dystrophies.It is often overlooked that muscular dystrophies affect head and body skeletal muscle differently. Moreover, these muscles develop differently. Specifically, head muscle and its stem cells develop from the non-somitic head mesoderm which also has cardiac competence. To which extent head muscle stem cells retain properties of the early head mesoderm and might even be able to switch between a skeletal muscle and cardiac fate is not known. This is due to the fact that the timing and mechanisms underlying head muscle stem cell development are still obscure. Consequently, it is not clear at which time point one should compare the properties of head mesodermal cells and head muscle stem cells.To shed light on this, we traced the emergence of head muscle stem cells in the key vertebrate models for myogenesis, chicken, mouse, frog and zebrafish, using Pax7 as key marker. Our study reveals a common theme of head muscle stem cell development that is quite different from the trunk. Unlike trunk muscle stem cells, head muscle stem cells do not have a previous history of Pax7 expression, instead Pax7 expression emerges de-novo. The cells develop late, and well after the head mesoderm has committed to myogenesis. We propose that this unique mechanism of muscle stem cell development is a legacy of the evolutionary history of the chordate head mesoderm
An unusual coordination polymer containing Cu+ ions and featuring possible Cu⋯Cu `cuprophilic' interactions: poly[di-μ-chlorido-(μ4-3,5-diaminobenzoato-κ4O:O′:N:N′)tricopper(I)(3 Cu—Cu)]
We thank the Higher Education Commission of Pakistan (grant No. 1-3/PM-PDFP-II/2006/22) for financial support.Peer reviewedPublisher PD
Hydrothermal synthesis and crystal structure of poly[bis- (μ3-3,4-diaminobenzoato) manganese], a layered coordination polymer
Acknowledgements The EPSRC National Crystallography Service (University of Southampton) is thanked for the intensity data collection. Funding information We thank the Higher Education Commission of Pakistan (grant No. 1–3/PM-PDFP-II/2006/22) for financial supportPeer reviewedPublisher PD
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