Evaluation of Biomass and Vegetative Propagation of Spilanthes Oleracea Jacq. (Asteraceae)

Spilanthes oleracea Jacq. is an herbaceous plant whose scientific literature attributes among others, anti-malarial and anti-bilharzia properties. These virtues justify the placing on the market of drugs based on the plant. Our study consisted on the one hand to evaluate the biomass of the plant on a soil of dune amended and on soil of unamended dune and to test its vegetative multiplication by transplanting, cuttings and layering. The results show that the growth of the species is greater on dune soil amended with an average biomass of 106.06 g compared to 71.06 g for un-amended soil plants. The transplanting of the plants and the layering were techniques that made it possible to multiply the plants. Spilanthes oleracea Jacq. can be produced using this agronomic data

Enquête Ethnobotanique Sur La Prise En Charge Traditionnelle De L’infertilité Féminine Dans La Région Sanitaire Des Savanes Au Togo

Introduction: The management of female infertility by the conventional medicine is very expensive and its coast is unavailable for the very poor populations. In Africa, an important recourses of medicinal plants are available for health care. Objective: The present study was led to recorder traditional remedies use to treat female infertility in the Sanitary Savannas Region of Togo. Methodology: For data collection, semi interview was used. Data were processed and analysed using ethnobotanical quantitative index. The Selection by Progressive Elimination (SPE) was essentially used for the choice of species. Results: With 51 practitioners interviewed, 79 recipes constituted by 87 species belonging to 48 botanical families were collected. Combretaceae (12,64 %) and Rubiaceae (5,7 %) were the most frequent families. Trees (36,78 %) and shrubs (27,58%) were the main ports. Roots (29,17 %) and leaves (27,5 %) were the most used parts. Recipes were prepared frequently by decoction (51,88 %) and powder (38,12%), and were principally taken orally (47,28 %) and by body bath (43,48 %). Sexually transmitted infections (STI) (143 citations) and Painful menstruations (PM) (108 citations) were the most frequent pathologies. The highest Informants consensus factors were 0,61 and 0,56 respectively for STI and PM. The most important Fidelity degrees was 25,49 % for STI related to Capsicum frutescens and Piper guineense. Related to Aframomum melegueta, Piper guineense and Zanthoxylum zanthoxyloides the Fidelity degree was 19,61% for PM and STI. Blighia sapida, Ganoderma colossus, Kigelia africana and Mangifera indica were selected. Conclusion: Plants with highest fidelity degree and those selected by SPE will be subjected to laboratory tests

Multicentric assessment of the efficacy and tolerability of dihydroartemisinin-piperaquine compared to artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in sub-Saharan Africa

<p>Abstract</p> <p>Background</p> <p>The choice of appropriate artemisinin-based combination therapy depends on several factors (cost, efficacy, safety, reinfection rate and simplicity of administration). To assess whether the combination dihydroartemisinin-piperaquine (DP) could be an alternative to artemether-lumefantrine (AL), the efficacy and the tolerability of the two products for the treatment of uncomplicated falciparum malaria in sub-Saharan Africa have been compared.</p> <p>Methods</p> <p>A multicentric open randomized controlled clinical trial of three-day treatment of DP against AL for the treatment of two parallel groups of patients aged two years and above and suffering from uncomplicated falciparum malaria was carried out in Cameroon, Côte d'Ivoire and Senegal. Within each group, patients were randomly assigned supervised treatment. DP was given once a day for three days and AL twice a day for three days. Follow-up visits were performed on day 1 to 4 and on day 7, 14, 21, 28 to evaluate clinical and parasitological results. The primary endpoint was the recovery rate by day 28.</p> <p>Results</p> <p>Of 384 patients enrolled, 197 were assigned DP and 187 AL. The recovery rates adjusted by genotyping, 99.5% in the DP group and 98.9% in the AL group, were not statistically different (p = 0.538). No Early Therapeutic Failure (ETF) was observed. At day 28, two patients in the DP group and five in AL group had recurrent parasitaemia with <it>Plasmodium falciparum</it>. In the DP group, after PCR genotyping, one of the two recurrences was classified as a new infection and the other as recrudescence. In AL group, two recurrences were classified after correction by PCR as recrudescence. All cases of recrudescence were classified as Late Parasitological Failure (LPF). In each group, a rapid recovery from fever and parasitaemia was noticed. More than 90% of patients did no longer present fever or parasitaemia 48 hours after treatment. Both drugs were well tolerated. Indeed, no serious adverse events were reported during the follow-up period. Most of the adverse events which developed were moderate and did not result in the treatment being stopped in either treatment group.</p> <p>Conclusions</p> <p>Dihydroartemisinin-piperaquine was as effective and well-tolerated as artemether-lumefantrine in the treatment of uncomplicated falciparum malaria. In addition, dihydroartemisinin-piperaquine, a single daily dose, could be an advantage over artemether-lumefantrine in Africa because of better treatment observance.</p

Ethno Apicultural Survey of Melliferous Plant Species in the Great Green Wall Widou and Koyli Alpha, Senegal

Dispositif de recherche interdisciplinaire sur les Interactions Hommes-Milieu