Consanguineous marriage, prepregnancy maternal characteristics and stillbirth risk: A population-based case-control study

Introduction. Consanguineous marriage is associated with increased risks for congenital anomalies, low birthweight, and other adverse perinatal outcomes. In this population-based, case-control study we investigated the association between consanguineous marriage (first-cousin marriage) and stillbirth risk, using prospectively collected information from prepregnancy visits. Material and methods. From 2007 to 2009, we identified 283 stillbirths (cases) and 2088 randomly selected live control births through prepregnancy visits in rural Golestan, Iran. The associations between consanguinity and prepregnancy maternal characteristics and stillbirth risk were examined using multivariate logistic regression. Results. The rate of consanguineous marriage was 19.4% among cases and 13.6% among controls. Consanguinity was associated with increased stillbirth risk [odds ratio (OR) 1.53; 95% CI 1.10-2.14]. The association was significantly increased for preterm stillbirth (< 37 gestational weeks) (OR 2.43; 95% CI 1.46-4.04) but not for term stillbirth (≥ 37 weeks) (OR 1.14; 95% CI 0.75-1.74). Low and high maternal age, underweight, obesity, nulliparity, a history of infertility or miscarriage, previous obstetric complications (preeclampsia, preterm delivery, and stillbirth in previous pregnancies) were also associated with increased stillbirth risks. Conclusions. Consanguineous marriage is associated with increased risk of stillbirth, particularly preterm stillbirth. Findings for other maternal risk factors for stillbirth in rural Iran are consistent with previously reported findings from high-income countries. © 2015 Nordic Federation of Societies of Obstetrics and Gynecology

Development and validation of two self-reported tools for insulin resistance and hypertension risk assessment in a European cohort : the Feel4Diabetes-study

Early identification of type 2 diabetes mellitus (T2DM) and hypertension (HTN) risk may improve prevention and promote public health. Implementation of self-reported scores for risk assessment provides an alternative cost-effective tool. The study aimed to develop and validate two easy-to-apply screening tools identifying high-risk individuals for insulin resistance (IR) and HTN in a European cohort. Sociodemographic, lifestyle, anthropometric and clinical data obtained from 1581 and 1350 adults (baseline data from the Feel4Diabetes-study) were used for the European IR and the European HTN risk assessment index respectively. Body mass index, waist circumference, sex, age, breakfast consumption, alcohol, legumes and sugary drinks intake, physical activity and sedentary behavior were significantly correlated with Homeostatic Model Assessment of IR (HOMA-IR) and/or HTN and incorporated in the two models. For the IR index, the Area Under the Curve (AUC), sensitivity and specificity for identifying individuals above the 75th and 95th of HOMA-IR percentiles were 0.768 (95%CI: 0.721–0.815), 0.720 and 0.691 and 0.828 (95%CI: 0.766–0.890), 0.696 and 0.778 respectively. For the HTN index, the AUC, sensitivity and specificity were 0.778 (95%CI: 0.680–0.876), 0.667 and 0.797. The developed risk assessment tools are easy-to-apply, valid, and low-cost, identifying European adults at high risk for developing T2DM or having HTN

Superweakly interacting dark matter from the Minimal Walking Technicolor

We study a superweakly interacting dark matter particle motivated by minimal walking technicolor theories. Our WIMP is a mixture of a sterile state and a state with the charges of a standard model fourth family neutrino. We show that the model can give the right amount of dark matter over a range of the WIMP mass and mixing angle. We compute bounds on the model parameters from the current accelerator data including the oblique corrections to the precision electroweak parameters, as well as from cryogenic experiments, Super-Kamiokande and from the IceCube experiment. We show that consistent dark matter solutions exist which satisfy all current constraints. However, almost the entire parameter range of the model lies within the the combined reach of the next generation experiments.Comment: 29 pages, 6 figure

Making Code Voting Secure against Insider Threats using Unconditionally Secure MIX Schemes and Human PSMT Protocols

Code voting was introduced by Chaum as a solution for using a possibly infected-by-malware device to cast a vote in an electronic voting application. Chaum's work on code voting assumed voting codes are physically delivered to voters using the mail system, implicitly requiring to trust the mail system. This is not necessarily a valid assumption to make - especially if the mail system cannot be trusted. When conspiring with the recipient of the cast ballots, privacy is broken. It is clear to the public that when it comes to privacy, computers and "secure" communication over the Internet cannot fully be trusted. This emphasizes the importance of using: (1) Unconditional security for secure network communication. (2) Reduce reliance on untrusted computers. In this paper we explore how to remove the mail system trust assumption in code voting. We use PSMT protocols (SCN 2012) where with the help of visual aids, humans can carry out $\mod 10$ addition correctly with a 99\% degree of accuracy. We introduce an unconditionally secure MIX based on the combinatorics of set systems. Given that end users of our proposed voting scheme construction are humans we \emph{cannot use} classical Secure Multi Party Computation protocols. Our solutions are for both single and multi-seat elections achieving: \begin{enumerate}[i)] \item An anonymous and perfectly secure communication network secure against a $t$-bounded passive adversary used to deliver voting, \item The end step of the protocol can be handled by a human to evade the threat of malware. \end{enumerate} We do not focus on active adversaries

STOVE: Seed treatments for organic vegetable production

The aim of the EU-financed research project „STOVE“ (Seed Treatments for Organic Vegetable Production) is to evaluate different methods potentially suited for seed treatment of vegetables in organic farming regarding their efficacy, to optimise these methods, and where feasible to combine them with each other. Scientists from seven European research institutions and a producer of organic vegetable seeds carry out the project

Victimization, crime propensity and deviance: a multinational test of general strain theory

General Strain Theory (GST) identifies victimization as one of the strains most strongly related to crime which, like other sources of strain, is moderated by individual and social factors. Recently, Agnew (2013) extended the theorization of coping strategies by proposing that the effects of strain on deviance are conditioned by individual and social factors in combination, rather than singly, which he labelled crime propensity. Tests of the propensity hypothesis have so far yielded mixed results, highlighting the value of additional studies. Whereas previous tests have focused on single countries, either in North America or Asia, we test the propensity hypothesis using data on adolescents in 25 countries collected through the International Self-Report Delinquency Study (ISRD3; n= 57,760). A series of OLS regressions show that the relationship between victimization and delinquency/substance use is conditioned by the effects of individuals’ crime propensity, thereby supporting the recent extension to GST

Developing and validating an experience sampling measure of aggression:The Aggression-ES Scale

Experience sampling methodologies are likely to play an important role in advancing our understanding of momentary influences on aggression, including short-term antecedent psychological states and situations. In this study, we evaluate whether a newly developed experiencing sampling measure of aggression, the Aggression Experience Sampler (Aggression-ES), provides a valid and reliable measure of aggression in experience sampling contexts. Participants were a convenience sample of 23 young adults recruited from the local University community. Data were collected using an experience sampling smartphone application over 8 days. They were analyzed using multilevel structural equation modeling. Our results support the within- and between-person reliability and the criterion validity of the Aggression-ES. The Aggression-ES represents a good choice of measure for use in experience sampling studies of aggression. Further work in other samples will help to provide further validity evidence for the measure

The Combined Roles of Moral Emotion and Moral Rules in Explaining Acts of Violence Using a Situational Action Theory Perspective

The roles of shame and guilt, and their relationships to empathy, have not been modeled adequately as key factors in moral decision-making in the study of violence. The role of moral emotion has been neglected in existing criminological research and this study seeks to develop current explanations of the comprehensive myriad of factors that play a role in moral crime decision-making. This research will test the different roles of empathy, shame, and guilt in violence decision-making using a situational action theory (SAT) perspective. Data taken from the Peterborough Adolescent and Young Adult Development Study (PADS+), a longitudinal study with a large representative sample, provide quantitative questionnaire indices to enable comparison of a persistent and frequent violent offender subsample (N = 48) with the remaining PADS+ study sample (N = 607). A striking majority of violent offenders report that they do not think it is wrong to commit violence, and do not care about it, that is, they lack shame and guilt, and report that violence comes as a morally acceptable and natural action alternative. Furthermore, violent offenders do not register the predicament of their victims; there is a distinct lack of empathy. This article demonstrates a key finding which has rarely been explored to date; regression analyses reveal an interaction effect whereby individuals with weak shame and guilt, combined specifically with weak moral rules, are more likely to commit acts of violence. The study findings provide strong support for the SAT of the role of weak morality in violence decision-making. To reduce the possibility of crime being seen as an action alternative, moral development programs should be developed and administered in childhood