337 research outputs found
A Theoretical Analysis of the Conditions for Unambiguous Node Localization in Sensor Networks
In this paper we provide a theoretical foundation for the problem of network localization in which some nodes know their locations and other nodes determine their locations by measuring distances or bearings to their neighbors. Distance information is the separation between two nodes connected by a sensing/communication link. Bearing is the angle between a sensing/communication link and the x-axis of a node's local coordinate system. We construct grounded graphs to model network localization and apply graph rigidity theory and parallel drawings to test the conditions for unique localizability and to construct uniquely localizable networks. We further investigate partially localizable networks
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A Theoretical Analysis of the Conditions for Unambiguous Node Localization in Sensor Networks
In this paper we provide a theoretical foundation for the problem of network localization in which some nodes know their locations and other nodes determine their locations by measuring distances or bearings to their neighbors. Distance information is the separation between two nodes connected by a sensing/communication link. Bearing is the angle between a sensing/communication link and the x-axis of a node's local coordinate system. We construct grounded graphs to model network localization and apply graph rigidity theory and parallel drawings to test the conditions for unique localizability and to construct uniquely localizable networks. We further investigate partially localizable networks
Microbial Community Composition Impacts Pathogen Iron Availability during Polymicrobial Infection
Iron is an essential nutrient for bacterial pathogenesis, but in the host, iron is tightly sequestered, limiting its availability for bacterial growth. Although this is an important arm of host immunity, most studies examine how bacteria respond to iron restriction in laboratory rather than host settings, where the microbiome can potentially alter pathogen strategies for acquiring iron. One of the most important transcriptional regulators controlling bacterial iron homeostasis is Fur. Here we used a combination of RNA-seq and chromatin immunoprecipitation (ChIP)-seq to characterize the iron-restricted and Fur regulons of the biofilm-forming opportunistic pathogen Aggregatibacter actinomycetemcomitans. We discovered that iron restriction and Fur regulate 4% and 3.5% of the genome, respectively. While most genes in these regulons were related to iron uptake and metabolism, we found that Fur also directly regulates the biofilm-dispersing enzyme Dispersin B, allowing A. actinomycetemcomitans to escape from iron-scarce environments. We then leveraged these datasets to assess the availability of iron to A. actinomycetemcomitans in its primary infection sites, abscesses and the oral cavity. We found that A. actinomycetemcomitans is not restricted for iron in a murine abscess mono-infection, but becomes restricted for iron upon co-infection with the oral commensal Streptococcus gordonii. Furthermore, in the transition from health to disease in human gum infection, A. actinomycetemcomitans also becomes restricted for iron. These results suggest that host iron availability is heterogeneous and dependent on the infecting bacterial community
Hepatitis C testing among three distinct groups of gay, bisexual and other men who have sex with men: a cross-sectional study in the Celtic nations
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Information Structures to Secure Control of Rigid Formations with Leader-Follower Structure
This paper is concerned with rigid formations of mobile autonomous agents using a leader-follower structure. A formation is a group of agents moving in real 2- or 3- dimensional space. A formation is called rigid if the distance between each pair of agents does not change over time under ideal conditions. Sensing/communication links between agents are used to maintain a rigid formation. Two agents connected by a sensing/communication link are called neighbors. There are two types of neighbor relations in rigid formations. In the first type, the neighbor relation is symmetric. In the second type, the neighbor relation is asymmetric. Rigid formations with a leader-follower structure have the asymmetric neighbor relation. A framework to analyze rigid formations with symmetric neighbor relations is given in our previous work. This paper suggests an approach to analyze rigid formations that have a leader-follower structure
Automatic detection of pitching and throwing events in baseball with inertial measurement sensors
Purpose: Throwing loads are known to be closely related to injury risk. However, for logistic reasons, typically only pitchers have their throws counted, and then only during innings. Accordingly, all other throws made are not counted, so estimates of throws made by players may be inaccurately recorded and underreported. A potential solution to this is the use of wearable microtechnology to automatically detect, quantify, and report pitch counts in baseball. This study investigated the accuracy of detection of baseball pitching and throwing in both practice and competition using a commercially available wearable microtechnology unit. Methods: Seventeen elite youth baseball players (mean ± SD age 16.5 ± 0.8 y, height 184.1 ± 5.5 cm, mass 78.3 ± 7.7 kg) participated in this study. Participants performed pitching, fielding, and throwing during practice and competition while wearing a microtechnology unit. Sensitivity and specificity of a pitching and throwing algorithm were determined by comparing automatic measures (ie, microtechnology unit) with direct measures (ie, manually recorded pitching counts). Results: The pitching and throwing algorithm was sensitive during both practice (100%) and competition (100%). Specificity was poorer during both practice (79.8%) and competition (74.4%). Conclusions: These findings demonstrate that the microtechnology unit is sensitive to detect pitching and throwing events, but further development of the pitching algorithm is required to accurately and consistently quantify throwing loads using microtechnology. © 2017 Human Kinetics, Inc
Effects of blood pressure and blood pressure-lowering treatment during the first 24 hours among patients in the Third International Stroke Trial of thrombolytic treatment for acute ischemic stroke
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