2,715 research outputs found

    Alien Registration- White, Leo F. (Portland, Cumberland County)

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    https://digitalmaine.com/alien_docs/21819/thumbnail.jp

    The CPSU and its members: between communism and postcommunism

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    Once dominant and unchallenged throughout the USSR, the Communist Party of the Soviet Union rapidly lost authority in the last two years of Soviet rule. Banned by Russian presidential decree after the failure of the attempted coup of August 1991, it was re-established in February 1993 and soon became the largest of the postcommunist parties. A 1992 survey of current and former party members as well as other Russians found that members were characterized by a relatively high degree of activism. They were disproportionately male, more affluent than non-members, and better provided with consumer goods. Younger respondents and religious believers were more likely to have left the party than their older colleagues. Those who still regarded themselves as party members were the most likely to oppose economic reform and support the collectivist principles of the communist era, particularly if they were activists; but the differences between members and non-members were not substantial, and both were found to hold generally pessimistic views on the postcommunist system. These findings suggest that, although former members will continue to be influential, CPSU membership is by itself likely to play a limited part in shaping the political direction of postcommunist Russia

    Effects of long-term inputs of fertiliser and irrigation on soil carbon under grazed pasture

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    Objective: To investigate and quantify the effects of long-term increases in pasture production caused by variable inputs of fertiliser and irrigation on soil profile carbon under permanent grazed pasture.Funding provided by the Agricultural and Marketing Research and Development Trust, The New Zealand Ministry of Agriculture and Forestry, and Environment Canterbury

    New simplified molecular design for functional T cell receptor

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    We have produced a chimeric single-chain T cell receptor (TcR) that combines the specific antibody recognition function and TcR/CD3 signaling properties within the same polypeptide chain. This hybrid molecule consisted of a single-chain antibody combining site that was connected over a short spacer to the transmembrane and cytoplasmic region of CD3. When expressed on TcR- or TcR+ T cell hybridomas it could mediate recognition of relevent target cells and subsequent production of lymphokines; i.e. it could functionally replace the TcR/CD3 complex. Therefore, the single-chain TcR model presented here represents an interesting and useful means for the creation of T cells with new specificities

    Epidemiology of cardiomyopathies and incident heart failure in a population-based cohort study

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    AIMS: The population prevalence of cardiomyopathies and the natural history of symptomatic heart failure (HF) and arrhythmia across cardiomyopathy phenotypes is poorly understood. Study aims were to estimate the population-diagnosed prevalence of cardiomyopathies and describe the temporal relationship between a diagnosis of cardiomyopathy with HF and arrhythmia. METHODS: People with cardiomyopathy (n=4116) were identified from linked electronic health records (~9 million individuals; 2000-2018) and categorised into hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy (DCM), arrhythmogenic right ventricular cardiomyopathy (ARVC), restrictive cardiomyopathy (RCM) and cardiac amyloidosis (CA). Cardiomyopathy point prevalence, rates of symptomatic HF and arrhythmia and timing relative to a diagnosis of cardiomyopathy were determined. RESULTS: In 2018, DCM was the most common cardiomyopathy. DCM and HCM were twice as common among men, with the reverse trend for ARVC. Between 2010 and 2018, prevalence increased for ARVC by 180% and HCM by 9%. At diagnosis, more patients with CA (66%), DCM (56%) and RCM (62%) had pre-existing HF compared with ARVC (29%) and HCM (27%). Among those free of HF at diagnosis of cardiomyopathy, annualised HF incidence was greatest in CA and DCM. Diagnoses of all cardiomyopathies clustered around the time of HF onset. CONCLUSIONS: The recorded prevalence of all cardiomyopathies increased over the past decade. Recognition of CA is generally preceded by HF, whereas individuals with ARVC or HCM more often developed HF after their cardiomyopathy diagnosis suggesting a more indolent course or better asymptomatic recognition. The clustering of HF and cardiomyopathy diagnoses suggests opportunities for presymptomatic or earlier diagnosis

    Retrofitting parallelism onto OCaml.

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    OCaml is an industrial-strength, multi-paradigm programming language, widely used in industry and academia. OCaml is also one of the few modern managed system programming languages to lack support for shared memory parallel programming. This paper describes the design, a full-fledged implementation and evaluation of a mostly-concurrent garbage collector (GC) for the multicore extension of the OCaml programming language. Given that we propose to add parallelism to a widely used programming language with millions of lines of existing code, we face the challenge of maintaining backwards compatibility--not just in terms of the language features but also the performance of single-threaded code running with the new GC. To this end, the paper presents a series of novel techniques and demonstrates that the new GC strikes a balance between performance and feature backwards compatibility for sequential programs and scales admirably on modern multicore processors
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