426 research outputs found

    Proactive Highly Ambulatory Sensor Routing (PHASeR) protocol for mobile wireless sensor networks

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    This paper presents a novel multihop routing protocol for mobile wireless sensor networks called PHASeR (Proactive Highly Ambulatory Sensor Routing). The proposed protocol uses a simple hop-count metric to enable the dynamic and robust routing of data towards the sink in mobile environments. It is motivated by the application of radiation mapping by unmanned vehicles, which requires the reliable and timely delivery of regular measurements to the sink. PHASeR maintains a gradient metric in mobile environments by using a global TDMA MAC layer. It also uses the technique of blind forwarding to pass messages through the network in a multipath manner. PHASeR is analysed mathematically based on packet delivery ratio, average packet delay, throughput and overhead. It is then simulated with varying mobility, scalability and traffic loads. The protocol gives good results over all measures, which suggests that it may also be suitable for a wider array of emerging applications

    Expression in hematological malignancies of a glucocorticoid receptor splice variant that augments glucocorticoid receptor-mediated effects in transfected cells

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    Glucocorticoids play an important role in the treatment of a number of hematological malignancies, such as multiple myeloma. The effects of glucocorticoids are mediated through the glucocorticoid receptor alpha, the abundance of which can be modulated by alternative splicing of the glucocorticoid receptor mRNA. Two splice variants of the glucocorticoid receptor mRNA have been described: glucocorticoid receptor beta, which reportedly has a dominant negative effect on the actions of the glucocorticoid receptor alpha, and glucocorticoid receptor P, of which the effects are unknown. In this study, we have investigated the expression levels of these two splice variants at the mRNA level in multiple myeloma cells and in a number of other hematological tumors. Although the glucocorticoid receptor beta mRNA was, if at all, expressed at very low levels, considerable amounts (up to 50% of the total glucocorticoid receptor mRNA) glucocorticoid receptor P mRNA was present in most hematological malignancies. In transient transfection studies in several cell types and in multiple myeloma cell lines, the glucocorticoid receptor P increased the activity of the glucocorticoid receptor alpha. These results suggest that the relative levels of the glucocorticoid receptor alpha and the glucocorticoid receptor P may play a role in the occurrence of glucocorticoid resistance in tumor cells during the treatment of hematological malignancies with glucocorticoids

    Convection in colloidal suspensions with particle-concentration-dependent viscosity

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    The onset of thermal convection in a horizontal layer of a colloidal suspension is investigated in terms of a continuum model for binary-fluid mixtures where the viscosity depends on the local concentration of colloidal particles. With an increasing difference between the viscosity at the warmer and the colder boundary the threshold of convection is reduced in the range of positive values of the separation ratio psi with the onset of stationary convection as well as in the range of negative values of psi with an oscillatory Hopf bifurcation. Additionally the convection rolls are shifted downwards with respect to the center of the horizontal layer for stationary convection (psi>0) and upwards for the Hopf bifurcation (psi<0).Comment: 8 pages, 6 figures, submitted to European Physical Journal

    Robust Ad-hoc Sensor Routing (RASeR) protocol for mobile wireless sensor networks

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    Robust Ad-hoc Sensor Routing (RASeR) is a novel protocol for data routing in mobile wireless sensor networks (MWSNs). It is designed to cope with the demanding requirements of emerging technologies, which require the reliable and low-latency delivery of packets in highly mobile conditions. RASeR uses blind forwarding, which is facilitated by a novel method of gradient maintenance. The problem of maintaining a gradient field in a changing topology, without flooding, is solved by using a global time division multiple access MAC. Furthermore, it is enhanced with the additional options of a supersede mode, to aid time-critical applications, reverse flooding, to allow sink-to-sensor commands and energy saving sleep cycles to reduce power consumption. Analytical expressions are derived and verified by simulation. RASeR is compared with the state-of-the-art MWSN routing protocols, PHASeR and MACRO, as well as the MANET protocols, AODV and OLSR. The results indicate that RASeR is a high performance protocol, which shows improvements over PHASeR, MACRO, AODV and OLSR. Tested over varying levels of mobility, scalability and traffic, the simulations yield near perfect PDR in many scenarios, as well as a low end-to-end delay, high throughput, low overhead and low energy consumption. The robustness of this protocol and its consistent reliability, low latency and additional features, makes it highly suitable to a wide number of applications. It is specifically applicable to highly mobile situations with a fixed number of nodes and small payloads

    HI in the Outskirts of Nearby Galaxies

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    The HI in disk galaxies frequently extends beyond the optical image, and can trace the dark matter there. I briefly highlight the history of high spatial resolution HI imaging, the contribution it made to the dark matter problem, and the current tension between several dynamical methods to break the disk-halo degeneracy. I then turn to the flaring problem, which could in principle probe the shape of the dark halo. Instead, however, a lot of attention is now devoted to understanding the role of gas accretion via galactic fountains. The current Λ\rm \Lambda cold dark matter theory has problems on galactic scales, such as the core-cusp problem, which can be addressed with HI observations of dwarf galaxies. For a similar range in rotation velocities, galaxies of type Sd have thin disks, while those of type Im are much thicker. After a few comments on modified Newtonian dynamics and on irregular galaxies, I close with statistics on the HI extent of galaxies.Comment: 38 pages, 17 figures, invited review, book chapter in "Outskirts of Galaxies", Eds. J. H. Knapen, J. C. Lee and A. Gil de Paz, Astrophysics and Space Science Library, Springer, in pres

    Atomic X-ray Spectroscopy of Accreting Black Holes

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    Current astrophysical research suggests that the most persistently luminous objects in the Universe are powered by the flow of matter through accretion disks onto black holes. Accretion disk systems are observed to emit copious radiation across the electromagnetic spectrum, each energy band providing access to rather distinct regimes of physical conditions and geometric scale. X-ray emission probes the innermost regions of the accretion disk, where relativistic effects prevail. While this has been known for decades, it also has been acknowledged that inferring physical conditions in the relativistic regime from the behavior of the X-ray continuum is problematic and not satisfactorily constraining. With the discovery in the 1990s of iron X-ray lines bearing signatures of relativistic distortion came the hope that such emission would more firmly constrain models of disk accretion near black holes, as well as provide observational criteria by which to test general relativity in the strong field limit. Here we provide an introduction to this phenomenon. While the presentation is intended to be primarily tutorial in nature, we aim also to acquaint the reader with trends in current research. To achieve these ends, we present the basic applications of general relativity that pertain to X-ray spectroscopic observations of black hole accretion disk systems, focusing on the Schwarzschild and Kerr solutions to the Einstein field equations. To this we add treatments of the fundamental concepts associated with the theoretical and modeling aspects of accretion disks, as well as relevant topics from observational and theoretical X-ray spectroscopy.Comment: 63 pages, 21 figures, Einstein Centennial Review Article, Canadian Journal of Physics, in pres

    Baryons: What, When and Where?

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    We review the current state of empirical knowledge of the total budget of baryonic matter in the Universe as observed since the epoch of reionization. Our summary examines on three milestone redshifts since the reionization of H in the IGM, z = 3, 1, and 0, with emphasis on the endpoints. We review the observational techniques used to discover and characterize the phases of baryons. In the spirit of the meeting, the level is aimed at a diverse and non-expert audience and additional attention is given to describe how space missions expected to launch within the next decade will impact this scientific field.Comment: Proceedings Review for "Astrophysics in the Next Decade: JWST and Concurrent Facilities", ed. X. Tielens, 38 pages, 10 color figures. Revised to address comments from the communit

    Physical Processes in Star Formation

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    © 2020 Springer-Verlag. The final publication is available at Springer via https://doi.org/10.1007/s11214-020-00693-8.Star formation is a complex multi-scale phenomenon that is of significant importance for astrophysics in general. Stars and star formation are key pillars in observational astronomy from local star forming regions in the Milky Way up to high-redshift galaxies. From a theoretical perspective, star formation and feedback processes (radiation, winds, and supernovae) play a pivotal role in advancing our understanding of the physical processes at work, both individually and of their interactions. In this review we will give an overview of the main processes that are important for the understanding of star formation. We start with an observationally motivated view on star formation from a global perspective and outline the general paradigm of the life-cycle of molecular clouds, in which star formation is the key process to close the cycle. After that we focus on the thermal and chemical aspects in star forming regions, discuss turbulence and magnetic fields as well as gravitational forces. Finally, we review the most important stellar feedback mechanisms.Peer reviewedFinal Accepted Versio

    Psychology and aggression

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68264/2/10.1177_002200275900300301.pd
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