12,965 research outputs found
Fluid containers and resealable septum therefor Patent
Manufacture of fluid containers from fused coated polyester sheets having resealable septu
Self-sealing closure enables access to several fluid containers
Self-sealing closure enables small amounts of specific biochemical solutions to be withdrawn from or added to containers in inaccessible or small spaces. It uses a self-sealing septum of a silicone elastomer through which a hypodermic needle can be inserted
Yang-Mills gravity in biconformal space
We write a gravity theory with Yang-Mills type action using the biconformal
gauging of the conformal group. We show that the resulting biconformal
Yang-Mills gravity theories describe 4-dim, scale-invariant general relativity
in the case of slowly changing fields. In addition, we systematically extend
arbitrary 4-dim Yang-Mills theories to biconformal space, providing a new arena
for studying flat space Yang-Mills theories. By applying the biconformal
extension to a 4-dim pure Yang-Mills theory with conformal symmetry, we
establish a 1-1, onto mapping between a set of gravitational gauge theories and
4-dim, flat space gauge theories.Comment: 27 pages; paper emphasis shifted to focus on gravity; references
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Implementation of the Crisis Resolution Team model in adult mental health settings: a systematic review.
Crisis Resolution Teams (CRTs) aim to offer an alternative to hospital admission during mental health crises, providing rapid assessment, home treatment, and facilitation of early discharge from hospital. CRTs were implemented nationally in England following the NHS Plan of 2000. Single centre studies suggest CRTs can reduce hospital admissions and increase service users' satisfaction: however, there is also evidence that model implementation and outcomes vary considerably. Evidence on crucial characteristics of effective CRTs is needed to allow team functioning to be optimised. This review aims to establish what evidence, if any, is available regarding the characteristics of effective and acceptable CRTs
Attosecond pulse shaping around a Cooper minimum
High harmonic generation (HHG) is used to measure the spectral phase of the
recombination dipole matrix element (RDM) in argon over a broad frequency range
that includes the 3p Cooper minimum (CM). The measured RDM phase agrees well
with predictions based on the scattering phases and amplitudes of the
interfering s- and d-channel contributions to the complementary photoionization
process. The reconstructed attosecond bursts that underlie the HHG process show
that the derivative of the RDM spectral phase, the group delay, does not have a
straight-forward interpretation as an emission time, in contrast to the usual
attochirp group delay. Instead, the rapid RDM phase variation caused by the CM
reshapes the attosecond bursts.Comment: 5 pages, 5 figure
The reduced cost of providing a nationally recognised service for familial hypercholesterolaemia
OBJECTIVE: Familial hypercholesterolaemia (FH) affects 1 in 500 people in the UK population and is associated with premature morbidity and mortality from coronary heart disease. In 2008, National Institute for Health and Care Excellence (NICE) recommended genetic testing of potential FH index cases and cascade testing of their relatives. Commissioners have been slow to respond although there is strong evidence of cost and clinical effectiveness. Our study quantifies the recent reduced cost of providing a FH service using generic atorvastatin and compares NICE costing estimates with three suggested alternative models of care (a specialist-led service, a dual model service where general practitioners (GPs) can access specialist advice, and a GP-led service).METHODS: Revision of existing 3?year costing template provided by NICE for FH services, and prediction of costs for running a programme over 10?years. Costs were modelled for the first population-based FH service in England which covers Southampton, Hampshire, Isle of Wight and Portsmouth (SHIP). Population 1.95 million.RESULTS: With expiry of the Lipitor (Pfizer atorvastatin) patent the cost of providing a 10-year FH service in SHIP reduces by 42.5% (£4.88 million on patent vs £2.80 million off patent). Further cost reductions are possible as a result of the reduced cost of DNA testing, more management in general practice, and lower referral rates to specialists. For instance a dual-care model with GP management of patients supported by specialist advice when required, costs £1.89 million.CONCLUSIONS: The three alternative models of care are now <50% of the cost of the original estimates undertaken by NICE
Phase field modeling of electrochemistry II: Kinetics
The kinetic behavior of a phase field model of electrochemistry is explored
for advancing (electrodeposition) and receding (electrodissolution) conditions
in one dimension. We described the equilibrium behavior of this model in [J. E.
Guyer, W. J. Boettinger, J.A. Warren, and G. B. McFadden, ``Phase field
modeling of electrochemistry I: Equilibrium'', cond-mat/0308173]. We examine
the relationship between the parameters of the phase field method and the more
typical parameters of electrochemistry. We demonstrate ohmic conduction in the
electrode and ionic conduction in the electrolyte. We find that, despite making
simple, linear dynamic postulates, we obtain the nonlinear relationship between
current and overpotential predicted by the classical ``Butler-Volmer'' equation
and observed in electrochemical experiments. The charge distribution in the
interfacial double layer changes with the passage of current and, at
sufficiently high currents, we find that the diffusion limited deposition of a
more noble cation leads to alloy deposition with less noble species.Comment: v3: To be published in Phys. Rev. E v2: Attempt to work around
turnpage bug. Replaced color Fig. 4a with grayscale 13 pages, 7 figures in 10
files, REVTeX 4, SIunits.sty, follows cond-mat/030817
Asymptotic properties of black hole solutions in dimensionally reduced Einstein-Gauss-Bonnet gravity
We study the asymptotic behavior of the spherically symmetric solutions of
the system obtained from the dimensional reduction of the six-dimensional
Einstein- Gauss-Bonnet action. We show that in general the scalar field that
parametrizes the size of the internal space is not trivial, but nevertheless
the solutions depend on a single parameter. In analogy with other models
containing Gauss-Bonnet terms, naked singularities are avoided if a minimal
radius for the horizon is assumed.Comment: 9 pages, plain Te
A vacuum (10(exp -9) Torr) friction apparatus for determining friction and endurance life of MoSx films
The first part of this paper describes an ultrahigh vacuum friction apparatus (tribometer). The tribometer can be used in a ball-on-disk configuration and is specifically designed to measure the friction and endurance life of solid lubricating films such as MoS(x) in vacuum at a pressure of 10 exp -7 Pa. The sliding mode is typically unidirectional at a constant rotating speed. The second part of this paper presents some representative friction and endurance life data for magnetron sputtered MoS(x) films (110 nm thick) deposited on sputter-cleaned 440 C stainless-steel disk substrates, which were slid against a 6-mm-diameter 440 C stainless-steel bearing ball. All experiments were conducted with loads of 0.49 to 3.6 N (average Hertzian contact pressure, 0.33 to 0.69 GPa), at a constant rotating speed of 120 rpm (sliding velocity ranging from 31 to 107 mm/s due to the range of wear track radii involved in the experiments), in a vacuum of 7 x 10 exp -7 Pa and at room temperature. The results indicate that there are similarities in friction behavior of MoS(x) films overs their life cycles regardless of load applied. The coefficient of friction (mu) decreases as load W increases according to mu = kW exp -1/3. The endurance life E of MoS(x) films decreases as the load W increases according to E = KW exp -1.4 for the load range. The load- (or contract-pressure-) dependent endurance life allows us to reduce the time for wear experiments and to accelerate endurance life testing of MoS(x) films. For the magnetron-sputtered MoS(x) films deposited on 440 C stainless-steel disks: the specific wear rate normalized to the load and the number of revolutions was 3 x 10 exp -8 mm exp 3/N-revolution; the specific wear rate normalized to the load and the total sliding distance was 8 x 10 exp -7 mm exp 3/N-m; and the nondimensional wear coefficient of was approximately 5 x 10 exp -6. The values are almost independent of load in the range 0.49 to 3.6 N (average Hertzian contact pressures of 0.33 to 0.69 GPa)
Under Pressure: Quenching Star Formation in Low-Mass Satellite Galaxies via Stripping
Recent studies of galaxies in the local Universe, including those in the
Local Group, find that the efficiency of environmental (or satellite) quenching
increases dramatically at satellite stellar masses below ~ . This suggests a physical scale where quenching transitions from a
slow "starvation" mode to a rapid "stripping" mode at low masses. We
investigate the plausibility of this scenario using observed HI surface density
profiles for a sample of 66 nearby galaxies as inputs to analytic calculations
of ram-pressure and viscous stripping. Across a broad range of host properties,
we find that stripping becomes increasingly effective at $M_{*} < 10^{8-9}\
{\rm M}_{\odot}n_{\rm halo} <
10^{-3.5}{\rm cm}^{-3}$), we find that stripping is not fully effective;
infalling satellites are, on average, stripped of < 40 - 70% of their cold gas
reservoir, which is insufficient to match observations. By including a host
halo gas distribution that is clumpy and therefore contains regions of higher
density, we are able to reproduce the observed HI gas fractions (and thus the
high quenched fraction and short quenching timescale) of Local Group
satellites, suggesting that a host halo with clumpy gas may be crucial for
quenching low-mass systems in Local Group-like (and more massive) host halos.Comment: updated version after review, now accepted to MNRAS; Accepted 2016
August 22. Received 2016 August 18; in original form 2016 June 2
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