A mathematical model of the effect of a predator on species diversity

Mathematical model determines reaction between new predator and microbe competitor when the competitor is the predator's sole nutrient resource. The model utilizes differential equations to describe the interactions with the specific growth rates, and analyzes these growth rates as they are affected by population density and nutrient concentration

Scale Dependence of Multiplier Distributions for Particle Concentration, Enstrophy and Dissipation in the Inertial Range of Homogeneous Turbulence

Turbulent flows preferentially concentrate inertial particles depending on their stopping time or Stokes number, which can lead to significant spatial variations in the particle concentration. Cascade models are one way to describe this process in statistical terms. Here, we use a direct numerical simulation (DNS) dataset of homogeneous, isotropic turbulence to determine probability distribution functions (PDFs) for cascade multipliers, which determine the ratio by which a property is partitioned into sub-volumes as an eddy is envisioned to decay into smaller eddies. We present a technique for correcting effects of small particle numbers in the statistics. We determine multiplier PDFs for particle number, flow dissipation, and enstrophy, all of which are shown to be scale dependent. However, the particle multiplier PDFs collapse when scaled with an appropriately defined local Stokes number. As anticipated from earlier works, dissipation and enstrophy multiplier PDFs reach an asymptote for sufficiently small spatial scales. From the DNS measurements, we derive a cascade model that is used it to make predictions for the radial distribution function (RDF) for arbitrarily high Reynolds numbers, $Re$, finding good agreement with the asymptotic, infinite $Re$ inertial range theory of Zaichik and Alipchenkov [New Journal of Physics 11, 103018 (2009)]. We discuss implications of these results for the statistical modeling of the turbulent clustering process in the inertial range for high Reynolds numbers inaccessible to numerical simulations.Comment: 21 pages, 14 figures, accepted for publication in Physical Review

Amino acid transport in poky (mi) mutants of Neurospora crassa

Amino acid transport in pok

Engaging rural preceptors in new longitudinal community clerkships during workforce shortage: a qualitative study

Background: In keeping with its mission to produce doctors for rural and regional Australia, the University of Wollongong, Graduate School of Medicine has established an innovative model of clinical education. This includes a 12-month integrated community-based clerkship in a regional or rural setting, offering senior students longitudinal participation in a \u27community of practice\u27 with access to continuity of patient care experiences, continuity of supervision and curriculum, and individualised personal and professional development. This required developing new teaching sites, based on attracting preceptors and providing them with educational and physical infrastructure. A major challenge was severe health workforce shortages. Methods: Before the new clerkship started, we interviewed 28 general practitioners to determine why they engaged as clerkship preceptors. Independent researchers conducted semi-structured interviews. Responses were transcribed for inductive qualitative content analysis. Results: The new model motivated preceptors to engage because it enhanced their opportunities to contribute to authentic learning when compared with the perceived limitations of short-term attachments. Preceptors appreciated the significant recognition of the value of general practice teaching and the honour of major involvement in the university. They predicted that the initiative would have positive effects on general practitioner morale and improve the quality of their practice. Other themes included the doctors\u27 commitment to their profession, \u27handing on\u27 to the next generation and helping their community to attract doctors in the future. Conclusions: Supervisors perceive that new models of clinical education offer alternative solutions to health care education, delivery and workforce. The longitudinal relationship between preceptor, student and community was seen as offering reciprocal benefits. General practitioners are committed to refining practice and ensuring generation of new members in their profession. They are motivated to engage in novel regional and rural longitudinal clinical clerkships as they perceive that they offer students an authentic learning experience and are a potential strategy to help address workforce shortages and maldistribution

Variations in rotational barriers of allyl and benzyl cations, anions, and radicals

High accuracy quantum chemical calculations show that the barriers to rotation of a CH2 group in the allyl cation, radical, and anion are 33, 14, and 21 kcal/mol, respectively. The benzyl cation, radical, and anion have barriers of 45, 11, and 24 kcal/mol, respectively. These barrier heights are related to the magnitude of the delocalization stabilization of each fully conjugated system. This paper addresses the question of why these rotational barriers, which at the Hückel level of theory are independent of the number of nonbonding electrons in allyl and benzyl, are in fact calculated to be factors that are of 2.4 and 4.1 higher in the cations and 1.5 and 1.9 higher in the anions than in the radicals. We also investigate why the barrier to rotation is higher for benzyl than for allyl in the cations and in the anions. Only in the radicals is the barrier for benzyl lower than that for allyl, as Hückel theory predicts should be the case. These fundamental questions in electronic structure theory, which have not been addressed previously, are related to differences in electron–electron repulsions in the conjugated and nonconjugated systems, which depend on the number of nonbonding electrons

The UK vs Sweden : Is the NHS really so bad?

Sheng-Chia Chung and colleagues report in The Lancet (23 January 2014) an international comparison of cardiovascular patient mortality between the UK and Sweden. They suggest that “more than 10000 deaths at 30 days would have been prevented or delayed had UK patients experienced the care of their Swedish counterparts.” Further, they estimate that 1741 deaths would have been prevented in the UK had the Swedish pattern of primary percutaneous coronary intervention (PCI) and beta-blocker use been replicated in the NHS from 2004 to 2010. However, their study does not provide convincing evidence that faster uptake of primary PCI or beta-blockers on discharge would have had an effect on cardiovascular patient mortality in the UK

On a Testing Methodology for the Mechanical Property Assessment of a New Low-Cost Titanium Alloy Derived from Synthetic Rutile

Mechanical property data of a low-cost titanium alloy derived directly from synthetic rutile is reported. A small-scale testing approach comprising consolidation via field-assisted sintering technology, followed by axisymmetric compression testing, has been designed to yield mechanical property data from small quantities of titanium alloy powder. To validate this approach and provide a benchmark, Ti-6Al-4V powder has been processed using the same methodology and compared with material property data generated from thermo-physical simulation software. Compressive yield strength and strain to failure of the synthetic rutile-derived titanium alloy were revealed to be similar to that of Ti-6Al-4V

The C-terminus of Bienertia sinuspersici Toc159 contains essential elements for its targeting and anchorage to the chloroplast outer membrane

Most nucleus-encoded chloroplast proteins rely on an N-terminal transit peptide (TP) as a post-translational sorting signal for directing them to the organelle. Although Toc159 is known to be a receptor for specific preprotein TPs at the chloroplast surface, the mechanism for its own targeting and integration into the chloroplast outer membrane is not completely understood. In a previous study, we identified a novel TP-like sorting signal at the C-terminus (CT) of a Toc159 homolog from the single-cell C4 species, Bienertia sinuspersici. In the current study, we have extended our understanding of the sorting signal using transient expression of fluorescently-tagged fusion proteins of variable-length, and with truncated and swapped versions of the CT. As was shown in the earlier study, the 56 residues of the CT contain crucial sorting information for reversible interaction of the receptor with the chloroplast envelope. Extension of this region to 100 residues in the current study stabilized the interaction via membrane integration, as demonstrated by more prominent plastid-associated signals and resistance of the fusion protein to alkaline extraction. Despite a high degree of sequence similarity, the plastid localization signals of the equivalent CT regions of Arabidopsis thaliana Toc159 homologs were not as strong as that of the B. sinuspersici counterparts. Together with computational and circular dichroism analyses of the CT domain structures, our data provide insights into the critical elements of the CT for the efficient targeting and anchorage of Toc159 receptors to the dimorphic chloroplasts in the single-cell C4 species.published_or_final_versio