57 research outputs found

    The Effect of Conditioning on the Flotation of Pyrrhotite in the Presence of Chlorite

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    The influence of conditioning on the flotation of pyrrhotite in the presence of chlorite was investigated through flotation tests, sedimentation tests, and X-ray photoelectron spectroscopy (XPS) analysis. The flotation results show that chlorite slimes dramatically impair the flotation of pyrrhotite. Sedimentation and flotation tests reveal that conditioning can effectively remove chlorite slimes from pyrrhotite surfaces, resulting in an enhanced flotation recovery of pyrrhotite. When mixed minerals were conditioned under the natural atmosphere, a faster conditioning speed and longer conditioning time decreased the flotation recovery of pyrrhotite. However, when mixed minerals were conditioned under a nitrogen atmosphere, a more intensive conditioning process provided better flotation results. XPS analyses illustrate that a faster conditioning speed and longer conditioning time under the natural atmosphere accelerates the oxidation of pyrrhotite, leading to a decrease in the flotation recovery of pyrrhotite

    Molecular Characterization and Expression of a Heat Shock Protein Gene (HSP90) from the Carmine Spider Mite, Tetranychus cinnabarinus (Boisduval)

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    In this study, the cDNA of Tetranychus cinnabarinus (Boisduval) (Acarina: Tetranychidae) HSP90 (designated TcHSP90) was cloned using a combination of the homology cloning and rapid amplification of cDNA ends (RACE) approaches. The full-length cDNA of TcHSP90 is 2595 bp, including a 5′-untranslated region (UTR) of 177 bp, 3′-UTR of 249 bp, and an open reading frame (ORF) of 2169 bp. The ORF encodes a polypeptide of 722 amino acids with a predicted molecular weight of 83.45 kDa and a theoretical isoelectric point of 4.81. There is an mRNA polyadenylation signal of ATTAAA at the positions 2558–2564. In addition, the expression pattern of TcHSP90 mRNA relative to that of β-actin gene in the three stains of T. cinnabarinus (AbR, abamectin-resistant strain; HR, heat-resistant strain; SS, the susceptible strain) were examined by using fluorescent real time quantitative PCR after the impact of abamectin, high and low temperature, respectively. The results showed that under the normal condition, the mRNA level of TcHSP90 was 1.64 and 1.29-fold higher in the AbR and HR than in SS, respectively. After 8 h treatment with abamectin, the TcHSP90 mRNA levels of SS, AbR, and HR were 1.25, 1.87, and 2.05-fold higher than those of their untreated controls, respectively. The TcHSP90 mRNA levels of SS, AbR, and HR were also significantly increased after being induced at 40° C for 1 h, and they were 3.76, 3.42, and 3.79-fold higher than those of their untreated controls, respectively. The mRNA level of TcHSP90 was also significantly increased after being induced at 4° C for 1 h. These results suggest that TcHSP90 might be involved in the abamectin and extreme temperature resistance or tolerance

    Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

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    This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites associated with smokin

    Can Brain Activities of Guided Metaphorical Restructuring Predict Therapeutic Changes?

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    The present study examined whether brain activities of metaphorical restructuring could predict improvements in emotion and general self-efficacy (GSES). Sixty-two anxious graduates were randomly assigned to either the metaphor group (n = 31) or the literal group (n = 31). After completing the pretest (T1), the partic-ipants were first presented with micro-counseling dialogues (MCD) to guide metaphorical or literal restructuring, and their functional brain activities were simultaneously recorded. They then completed the posttest (T2) and 1 week's follow-up (T3). It was found that (1) compared with the literal group, the metaphor group had more insightful experiences, a greater increase in positive affect and GSES at T2, and a greater decrease in psycholog-ical distress at T2 and T3; (2) the metaphor group showed a greater activation in the left inferior frontal gyrus (IFG) and bilateral temporal gyrus, and further activation in the left hippocampus positively predicted T2 GSES scores while that in the IFG and left hippocampus positively predicted the reduction slope of distress over the three time points. One important limitation is that the results should be interpreted with caution when generalizing to clinical anxiety samples due to the participants were graduate students with anxiety symptoms rather than clinical sam-ple. These results indicated that metaphor restructuring produced greater symptom improvements, and activation in the hippocampus and IFG could predict these symptom improvements. This suggests that the activation of the two regions during the restructuring intervention may be a neural marker for symptom improvements.(c) 2023 IBRO. Published by Elsevier Ltd. All rights reserved

    High Precision Self-Mixing Interferometer Based on Reflective Phase Modulation Method

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    In this paper, a novel self-mixing interferometer based on reflective phase modulation (RPM) method has been developed to perform micro-displacement reconstruction with nanometer accuracy. Broaden harmonic components spectrum of the self-mixing signal is produced by employing a high-frequency vibrating reflective mirror as the phase modulation device. Phase demodulation is implemented applying the orthogonal demodulation algorithm subject to the signal spectrum, in which orthogonal signal can be extracted from the harmonic components of the expanded Bessel function. The principle and signal processing approach are introduced in detail, and the simulation results indicate that the reconstruction error can be reduced as the number of reflections increases. A series of experiments at different vibration amplitudes show that the reconstructed errors are all less than 10 nm with modulation frequency of 1 kHz. And the minimum error of 3 nm has been achieved at the measured amplitude of 229 nm, which demonstrates the technical-superiority and high-performance of the method

    Obtaining High Fringe Precision in Self-Mixing Interference Using a Simple External Reflecting Mirror

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    Structure and Reactivity of Anatase TiO<sub>2</sub>(001)-(1 × 4) Surface

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    TiO<sub>2</sub> anatase (001) surface which usually exhibits (1 × 4) surface reconstruction has attracted lots of research interests for its potentially high photocatalytic activity. The atomic structure of the reconstruction and defects of this surface play an important role on its reactivity. Besides the well-known add-molecule model reconstruction, the add-oxygen model (AOM) for anatase (001)-(1 × 4)-reconstructed surface by adding one oxygen atom to each Ti<sub>4C</sub> atom was proposed. In this work, we investigate the geometric and electronic structures as well as the H<sub>2</sub>O and O<sub>2</sub> adsorption behavior on anatase (001) surface with AOM systematically. The different defect structures including oxygen vacancy (O<sub>V</sub>), Ti interstitial (Ti<sub>ini</sub>), and TiO<sub>2</sub> vacancy (TiO<sub>2</sub>)<sub>V</sub> are also studied. Our calculations show that oxidization makes the AOM surface inert to molecular adsorption. The TiO<sub>2</sub> vacancy with Ti interstitial, (TiO<sub>2</sub>)<sub>V</sub>–Ti<sub>ini</sub>, is found to be the only reactive site for water and oxygen molecules adsorbing on the TiO<sub>2</sub> anatase (001)-(1 × 4)-reconstructed surface. The investigations based on AOM can explain the atomic-resolved scanning tunneling microscopy results appropriately. Our systematic study of the AOM reconstruction of anatase (001) provides new insights into the understanding of the structure and reactivity on this surface

    Correlations between Ape1/Ref-1, ICAM-1 and IL-17A Levels in Serum and Radiation Pneumonitis for Local Advanced Non-small Cell Lung Cancer Patients

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    Background and objective The main manifestations of radiation pneumonitis are injury of alveolar epithelial and endothelial cells, abnormal expression of cytokines, abnormal proliferation of fibroblasts and synthesis of fibrous matrix. The occurrence of radiation pneumonitis is associated with multiplecytokine level abnormality. These cytokines can also be used as bio-markers to predict the occurrence of radiation pneumonitis. This study was to evaluate the correlation between the change of apurinic/apyrimidinic endonuclease 1/redox factor-1 (Ape1/Ref-1), intercellular adhesion molecules 1 (ICAM-1) and interleukin-17A (IL-17A) before and after radiotherapy and radiation pneumonitis for local advanced non-small cell lung cancer (NSCLC) patients with concurrent chemoradiotherapy. Methods NSCLC patients (68 cases) were treated with concurrent radiotherapy and chemotherapy, every patient’s normal tissue were controlled with a same radation dose. 68 local advanced NSCLC patients with concurrent chemoradiotherapy were detected the levels of Ape1/Ref-1, ICAM-1 and IL-17A in serum by ELISA before radiotherapy and in the 14th week after radiotherapy. Acute and advanced radiation pulmonary injury was graded according to Radiation Therapy Oncology Group/European Organization For Research and Treatment (RTOG/EORTC) diagnostic and grading criteria. Grade 2 or more radiation pneumonitis was taken as the main end point. Results Eighteen cases out of 68 developed radiation pneumonitis, 50 of 68 cases have no radiation pneumonia development. There was no significant change of Ape1/Ref-1 levels before and after radiotherapy in radiation pneumonitis group (P>0.05). There was no significant change of Ape1/Ref-1 concentration in serum after radiotherapy between radiation pneumonitis group and non-radiation pneumonitis group (P>0.05). Compared with before radiotherapy, upregulation degree of ICAM-1 levels in radiation pneumonitis group was significantly higher than that in non- radiation pneumonitis group (P<0.05). There was no significant change of IL-17A concentration before and after radiotherapy in radiation pneumonitis group, but after radiotherapy IL-17A concentration in serum were remarkably higher than that in non-radiation pneumonitis group (P<0.05). Correlation analysis found that the change of ICAM-1 before and after radiotherapy has no obvious correlation with the incidence of radiation pneumonitis, and IL-17A change has obvious correlation with the incidence of radiation pneumonitis. Conclusion On the basis of strictly controlling radiation dose on normal tissue, IL-17A in serum could be the predictive factors of radiation pneumonitis for local advanced NSCLC patients with concurrent chemoradiotherapy
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