4,641 research outputs found

    Densification of powder metallurgy billets by a roll consolidation technique

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    Container design is used to convert partially densified powder metallurgy compacts into fully densified slabs in one processing step. Technique improves product yield, lowers costs and yields great flexibility in process scale-up. Technique is applicable to all types of fabricable metallic materials that are produced from powder metallurgy process

    Resolution of Occlusive Carotid Artery Thrombus Treated with Anticoagulation as Demonstrated on Duplex Ultrasonography.

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    BACKGROUND AND PURPOSE: While the majority of cerebral ischemic events due to carotid occlusive disease result from atherosclerotic plaque rupture, intraluminal carotid artery thrombus occasionally occurs in patients without preexisting carotid atherosclerosis. Identification of nonatherosclerotic thrombus as the cause of the carotid occlusive disease can obviate the need for an interventional procedure, and resolution of thrombus can be monitored with B-mode duplex ultrasonography. METHODS: We reviewed 3 patients treated on The Mount Sinai Hospital Stroke Unit with anticoagulation for nonatherosclerotic carotid thrombi and followed with serial Doppler ultrasonogrpahy for resolution of thrombus. RESULTS: Occlusive carotid thrombus was successfully treated in all 3 patients with systemic anticoagulation. B-mode duplex ultrasonography allowed for demonstration of resolving thrombus. CONCLUSION: Differentiation between a stenotic plaque and occlusive thrombus can be achieved by ultrasonographic analysis of thrombus morphology, attachment site potential, and characteristics of a resolving thrombus. Systemic anticoagulation can safely and effectively eliminate the risk for future embolization and complete occlusion of the carotid artery in patients who present with transient ischemic events or completed infarcts of small size

    The Federal Trade Commission: Progress and a New Profile

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    Caspar W. Weinberger to Senator James O. Eastland, 3 October 1972

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    Copy typed letter signed dated 3 October 1972 from Eastland to Caspar W. Weinberger, re: Tennessee-Tombigbee Waterway; 2 pages.https://egrove.olemiss.edu/joecorr_f/1012/thumbnail.jp

    The Federal Trade Commission: Progress and a New Profile

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    Caspar W. Weinberger to Senator James O. Eastland, 18 March, 1970

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    Typed letter signed dated 18 March 1971 from Caspar W. Weinberger to Eastland, re: veterinary medicine school funding, Health Manpower Act; 2 pages. Attached: typed letter dated 4 March 1971 from Eastland to George P. Schultz, Director of Office of Management & Budget, re: above topic & Louisiana State University, Mississippi cattle industry. Attached: copy typed letter signed dated 12 March 1971 from Schultz to Senator Allen J. Ellender, re: veterinary medicine school funding; 2 pages. Attached: carbon typed letter dated 4 March 1971 from Eastland to Schultz, re: above topic & livestock; 2 pages. Attached: typed memorandum dated 23 February 1971 from Jim Guirard to Bill [Simpson], re: attached letter. Attached: copy typed letter dated 19 February 1971 from Ellender to Schultz, re: above topic. Attached: carbon typed letter dated 16 February 1971 from Eastland to Everett D. Besch, Dean of School of Veterinary Medicine at Agricultural & Mechanical College in Baton Rouge, LA, re: above topic. Attached: copy typed letter dated 4 February 1971 from Besch to Eastland, re: above topic; 2 pages.https://egrove.olemiss.edu/joecorr_f/1011/thumbnail.jp

    Caspar W. Weinberger to Senator James O. Eastland, 16 December, 1970

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    Typed letter signed dated 16 December 1970 from Caspar W. Weinberger, Deputy Director of Office of Management & Budget, to Eastland, re: Tennessee-Tombigbee Waterway.https://egrove.olemiss.edu/joecorr_f/1010/thumbnail.jp

    Development of dispersion strengthened nickel-chromium alloy (Ni-Cr-ThO2) sheet for space shuttle vehicles, part 2

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    Two dispersion strengthened nickel base alloy systems were developed for use at temperatures up to 1204 C(2200 F); TD nickel chromium (TDNiCr) and TD nickel chromium aluminum (TDNiCrA1). They are considered candidate materials for use on the thermal protection systems of the space shuttle and for long term use in aircraft gas turbine engine applications. Improved manufacturing processes were developed for the fabrication of TDNiCr sheet and foil to specifications. Sheet rolling process studies and extrusion studies were made on two aluminum containing alloys: Ni-16%Cr-3.5%A1-2%ThO2 and Ni-16%Cr-5.0%A12%ThO2. Over 1600 kg.(3500 lb.) of plate, sheet, foil, bar and extrusion products were supplied to NASA Centers for technology studies

    A bacterial facultative parasite of Gracilaria conferta

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    Bacterial epiphytes of Gracilaria conferta were quantified. Saprophytic bacteria reached 350 times and agar degraders 25000 times higher numbers g-1 algal wet wt on tissues infected with the 'white tips disease', as compared to healthy tissues. A bacterial inducing agent of the 'white tips disease' was detected. Addition of 10(2) to 10(3) cells of this isolate ml-1 medium led to increased rates of infection. This effect did not occur if the isolate was autoclaved before addition. The virulent bacteria could always be isolated from infected tissues. It frequently, but not always, infected G. conferta and should be regarded as a facultative parasite. Several factors influenced the disease development. Temperatures above 20-degrees-C, in combination with photon flux densities of more than 200 muE m-2 s-1, increased the rate of infection. Relatively low amounts (more than 25 mug ml-1) of certain organic nutrients (peptone and yeast extract) led to strong manifestations of the disease. Addition of agar did not cause any symptoms, while 5 mg l-1 of the antibiotic rifampicin prevented the alga from being infected

    Monitoring Protein Splicing Using In-gel Fluorescence Immediately Following SDS-PAGE

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    Inteins garner significant interest from both basic and applied researchers due to their unique catalytic abilities. Herein, we describe a protocol for accurately monitoring protein splicing without purification using in-gel fluorescence immediately following Tris-Glycine SDS-PAGE. Following expression in Escherichia coli, cells are lysed by sonication, cell supernatants are separated using Tris- Glycine SDS-PAGE, and superfolder GFP (sfGFP) fluorescence is directly visualized within gels. This method is rapid, with sfGFP immediately imaged following SDS-PAGE without staining. Further, sfGFP can be specifically detected in complex samples such as E. coli cell supernatants, proteins run at expected masses, and all steps can be performed at ambient temperature. This strategy is broadly applicable beyond the study of protein splicing and can be used for sensitive and specific visualization of superfolder sfGFP-tagged proteins in-gel
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