81 research outputs found
A Mentoring Network for Novice and Experienced Music Teachers: Concept, Design, Outcomes, and Recommendations
Two university music education faculty aimed to expand mentoring beyond a one-to-one relationship to a more collaborative approach by creating a year-long online mentoring network of experienced and novice music educators. The purpose of this article is to describe the networkâs structure and content, and discuss outcomes and recommendations based on participating teachersâ perspectives and experiences. Network materials promoted discussion and reflection on various music teaching and learning topics; the sharing of strategies, ideas, and resources; and mutual support and encouragement. Participants discussed topics with direct application for their classes and shared rewarding teaching moments, student successes, positive assessment outcomes, and struggles with fatigue and lack of student engagement. They stated the network provided a supportive space that facilitated connection and reflection, empathetic feedback, and teaching strategy and resource suggestions. Recommendations included more active opportunities to engage with and build relationships with each other, synchronous activities via videoconferencing platforms, and more facilitator participation
Continued reduction and analysis of data from the Dynamics Explorer Plasma Wave Instrument
The plasma wave instrument on the Dynamics Explorer 1 spacecraft provided measurements of the electric and magnetic components of plasma waves in the Earth's magnetosphere. Four receiver systems processed signals from five antennas. Sixty-seven theses, scientific papers and reports were prepared from the data generated. Data processing activities and techniques used to analyze the data are described and highlights of discoveries made and research undertaken are tabulated
Science through Machine Learning: Quantification of Poststorm Thermospheric Cooling
Machine learning (ML) is often viewed as a black-box regression technique
that is unable to provide considerable scientific insight. ML models are
universal function approximators and - if used correctly - can provide
scientific information related to the ground-truth dataset used for fitting. A
benefit to ML over parametric models is that there are no predefined basis
functions limiting the phenomena that can be modeled. In this work, we develop
ML models on three datasets: the Space Environment Technologies (SET) High
Accuracy Satellite Drag Model (HASDM) density database, a spatiotemporally
matched dataset of outputs from the Jacchia-Bowman 2008 Empirical Thermospheric
Density Model (JB2008), and an accelerometer-derived density dataset from
CHAllenging Minisatellite Payload (CHAMP). These ML models are compared to the
Naval Research Laboratory Mass Spectrometer and Incoherent Scatter radar
(NRLMSIS 2.0) model to study the presence of post-storm cooling in the
middle-thermosphere. We find that both NRLMSIS 2.0 and JB2008-ML do not account
for post-storm cooling and consequently perform poorly in periods following
strong geomagnetic storms (e.g. the 2003 Halloween storms). Conversely,
HASDM-ML and CHAMP-ML do show evidence of post-storm cooling indicating that
this phenomenon is present in the original datasets. Results show that density
reductions up to 40% can occur 1--3 days post-storm depending on location and
the strength of the storm
Governance and Evidence-Based Medicine: Lessons from the Organ Procurement and Transplantation Network
Freshwater monitoring by nanopore sequencing.
While traditional microbiological freshwater tests focus on the detection of specific bacterial indicator species, including pathogens, direct tracing of all aquatic DNA through metagenomics poses a profound alternative. Yet, in situ metagenomic water surveys face substantial challenges in cost and logistics. Here, we present a simple, fast, cost-effective and remotely accessible freshwater diagnostics workflow centred around the portable nanopore sequencing technology. Using defined compositions and spatiotemporal microbiota from surface water of an example river in Cambridge (UK), we provide optimised experimental and bioinformatics guidelines, including a benchmark with twelve taxonomic classification tools for nanopore sequences. We find that nanopore metagenomics can depict the hydrological core microbiome and fine temporal gradients in line with complementary physicochemical measurements. In a public health context, these data feature relevant sewage signals and pathogen maps at species level resolution. We anticipate that this framework will gather momentum for new environmental monitoring initiatives using portable devices
The technologies of isolation: apocalypse and self in Kurosawa Kiyoshi's Kairo
In this investigation of the Japanese film Kairo, I contemplate how the horrors present in the film relate to the issue of self, by examining a number of interlocking motifs. These include thematic foci on disease and technology which are more intimately and inwardly focused that the film's conclusion first appears to suggest. The true horror here, I argue, is ontological: centred on the self and its divorcing from the exterior world, especially founded in an increased use of and reliance on communicative technologies. I contend that these concerns are manifested in Kairo by presenting the spread of technology as disease-like, infecting the city and the individuals who are isolated and imprisoned by their urban environment. Finally, I investigate the meanings of the apocalypse, expounding how it may be read as hopeful for the future rather than indicative of failure or doom
An Open-System Quantum Simulator with Trapped Ions
The control of quantum systems is of fundamental scientific interest and
promises powerful applications and technologies. Impressive progress has been
achieved in isolating the systems from the environment and coherently
controlling their dynamics, as demonstrated by the creation and manipulation of
entanglement in various physical systems. However, for open quantum systems,
engineering the dynamics of many particles by a controlled coupling to an
environment remains largely unexplored. Here we report the first realization of
a toolbox for simulating an open quantum system with up to five qubits. Using a
quantum computing architecture with trapped ions, we combine multi-qubit gates
with optical pumping to implement coherent operations and dissipative
processes. We illustrate this engineering by the dissipative preparation of
entangled states, the simulation of coherent many-body spin interactions and
the quantum non-demolition measurement of multi-qubit observables. By adding
controlled dissipation to coherent operations, this work offers novel prospects
for open-system quantum simulation and computation.Comment: Pre-review submission to Nature. For an updated and final version see
publication. Manuscript + Supplementary Informatio
Atmospheric Escape Processes and Planetary Atmospheric Evolution
The habitability of the surface of any planet is determined by a complex
evolution of its interior, surface, and atmosphere. The electromagnetic and
particle radiation of stars drive thermal, chemical and physical alteration of
planetary atmospheres, including escape. Many known extrasolar planets
experience vastly different stellar environments than those in our Solar
system: it is crucial to understand the broad range of processes that lead to
atmospheric escape and evolution under a wide range of conditions if we are to
assess the habitability of worlds around other stars. One problem encountered
between the planetary and the astrophysics communities is a lack of common
language for describing escape processes. Each community has customary
approximations that may be questioned by the other, such as the hypothesis of
H-dominated thermosphere for astrophysicists, or the Sun-like nature of the
stars for planetary scientists. Since exoplanets are becoming one of the main
targets for the detection of life, a common set of definitions and hypotheses
are required. We review the different escape mechanisms proposed for the
evolution of planetary and exoplanetary atmospheres. We propose a common
definition for the different escape mechanisms, and we show the important
parameters to take into account when evaluating the escape at a planet in time.
We show that the paradigm of the magnetic field as an atmospheric shield should
be changed and that recent work on the history of Xenon in Earth's atmosphere
gives an elegant explanation to its enrichment in heavier isotopes: the
so-called Xenon paradox
Freshwater monitoring by nanopore sequencing
Many water-dwelling bacteria can cause severe diseases such as cholera, typhoid or leptospirosis. One way to prevent outbreaks is to test water sources to find out which species of microbes they contain, and at which levels.
Traditionally, this involves taking a water sample, followed by growing a few species of âindicator bacteriaâ that help to estimate whether the water is safe. An alternative technique, called metagenomics, has been available since the mid-2000s. It consists in reviewing (or âsequencingâ) the genetic information of most of the bacteria present in the water, which allows scientists to spot harmful species. Both methods, however, require well-equipped laboratories with highly trained staff, making them challenging to use in remote areas.
The MinION is a pocket-sized device that â when paired with a laptop or mobile phone â can sequence genetic information âon the goâ. It has already been harnessed during Ebola, Zika or SARS-CoV-2 epidemics to track the genetic information of viruses in patients and environmental samples. However, it is still difficult to use the MinION and other sequencers to monitor bacteria in water sources, partly because the genetic information of the microbes is highly fragmented during DNA extraction.
To address this challenge, Urban, Holzer et al. set out to optimise hardware and software protocols so the MinION could be used to detect bacterial species present in rivers. The tests focussed on the River Cam in Cambridge, UK, a waterway which faces regular public health problems: local rowers and swimmers often contract waterborne infections, sometimes leading to river closures.
For six months, Urban, Holzer et al. used the MinION to map out the bacteria present across nine river sites, assessing the diversity of species and the presence of disease-causing microbes in the water. In particular, the results showed that optimising the protocols made it possible to tell the difference between closely related species â an important feature since harmful and inoffensive bacteria can sometimes be genetically close. The data also revealed that the levels of harmful bacteria were highest downstream of urban river sections, near a water treatment plant and river barge moorings. Together, these findings demonstrate that optimising MinION protocols can turn this device into a useful tool to easily monitor water quality.
Around the world, climate change, rising urbanisation and the intensification of agriculture all threaten water quality. In fact, access to clean water is one of the United Nations sustainable development goals for 2030. Using the guidelines developed by Urban, Holzer et al., communities could harness the MinION to monitor water quality in remote areas, offering a cost-effective, portable DNA analysis tool to protect populations against deadly diseases
The Metagenome of an Anaerobic Microbial Community Decomposing Poplar Wood Chips
This study describes the composition and metabolic potential of a lignocellulosic biomass degrading community that decays poplar wood chips under anaerobic conditions. We examined the community that developed on poplar biomass in a non-aerated bioreactor over the course of a year, with no microbial inoculation other than the naturally occurring organisms on the woody material. The composition of this community contrasts in important ways with biomass-degrading communities associated with higher organisms, which have evolved over millions of years into a symbiotic relationship. Both mammalian and insect hosts provide partial size reduction, chemical treatments (low or high pH environments), and complex enzymatic âsecretomesâ that improve microbial access to cell wall polymers. We hypothesized that in order to efficiently degrade coarse untreated biomass, a spontaneously assembled free-living community must both employ alternative strategies, such as enzymatic lignin depolymerization, for accessing hemicellulose and cellulose and have a much broader metabolic potential than host-associated communities. This would suggest that such a community would make a valuable resource for finding new catalytic functions involved in biomass decomposition and gaining new insight into the poorly understood process of anaerobic lignin depolymerization. Therefore, in addition to determining the major players in this community, our work specifically aimed at identifying functions potentially involved in the depolymerization of cellulose, hemicelluloses, and lignin, and to assign specific roles to the prevalent community members in the collaborative process of biomass decomposition. A bacterium similar to Magnetospirillum was identified among the dominant community members, which could play a key role in the anaerobic breakdown of aromatic compounds. We suggest that these compounds are released from the lignin fraction in poplar hardwood during the decay process, which would point to lignin-modification or depolymerization under anaerobic conditions
- âŠ