Gefangen im Netz: kritische Anmerkungen zum Umgang mit der Netzwerkrhetorik

Durch den inflationären Gebrauch des Begriffs «Netzwerk» stellt sich die Frage, ob etwas, an dem mehrere Akteure oder Institutionen beteiligt sind, «Kein-Netzwerk» sein kann. Weiterbildungsanbieter, Regionen - selbst unsere moderne Gesellschaft - scheinen vernetzt. Aber stimmt das Bild von innovationsfreudigen Netzwerken in der Weiterbildung, oder handelt es sich um eine rhetorisch gut positionierte Worthülse, die von den wirklichen Herausforderungen ablenkt

Radio Frequency Interference /RFI/ design guide for aerospace communications systems

Radio frequency interference design guide for aerospace communications system

Dileptons in a coarse-grained transport approach

We calculate dilepton spectra in heavy-ion collisions using a coarse-graining approach to the simulation of the created medium with the UrQMD transport model. This enables the use of dilepton-production rates evaluated in equilibrium quantum-field theory at finite temperatures and chemical potentials.Comment: 4 pages, 2 figures, contribution to the proceedings of "The 15th International Conference on Strangeness in Quark Matter" (SQM 2015), 06-11 July in Dubna, Russi

Site-selective protein modification via disulfide rebridging for fast tetrazine/trans-cyclooctene bioconjugation

An inverse electron demand Diels–Alder reaction between tetrazine and trans-cyclooctene (TCO) holds great promise for protein modification and manipulation. Herein, we report the design and synthesis of a tetrazine-based disulfide rebridging reagent, which allows the site-selective installation of a tetrazine group into disulfide-containing peptides and proteins such as the hormone somatostatin (SST) and the antigen binding fragment (Fab) of human immunoglobulin G (IgG). The fast and efficient conjugation of the tetrazine modified proteins with three different TCO-containing substrates to form a set of bioconjugates in a site-selective manner was successfully demonstrated for the first time. Homogeneous, well-defined bioconjugates were obtained underlining the great potential of our method for fast bioconjugation in emerging protein therapeutics. The formed bioconjugates were stable against glutathione and in serum, and they maintained their secondary structure. With this work, we broaden the scope of tetrazine chemistry for site-selective protein modification to prepare well-defined SST and Fab conjugates with preserved structures and good stability under biologically relevant conditions

Canonical decomposition of linear differential operators with selected differential Galois groups

We revisit an order-six linear differential operator having a solution which is a diagonal of a rational function of three variables. Its exterior square has a rational solution, indicating that it has a selected differential Galois group, and is actually homomorphic to its adjoint. We obtain the two corresponding intertwiners giving this homomorphism to the adjoint. We show that these intertwiners are also homomorphic to their adjoint and have a simple decomposition, already underlined in a previous paper, in terms of order-two self-adjoint operators. From these results, we deduce a new form of decomposition of operators for this selected order-six linear differential operator in terms of three order-two self-adjoint operators. We then generalize the previous decomposition to decompositions in terms of an arbitrary number of self-adjoint operators of the same parity order. This yields an infinite family of linear differential operators homomorphic to their adjoint, and, thus, with a selected differential Galois group. We show that the equivalence of such operators is compatible with these canonical decompositions. The rational solutions of the symmetric, or exterior, squares of these selected operators are, noticeably, seen to depend only on the rightmost self-adjoint operator in the decomposition. These results, and tools, are applied on operators of large orders. For instance, it is seen that a large set of (quite massive) operators, associated with reflexive 4-polytopes defining Calabi-Yau 3-folds, obtained recently by P. Lairez, correspond to a particular form of the decomposition detailed in this paper.Comment: 40 page

Cosmological Evolution of Supergiant Star-Forming Clouds

In an exploration of the birthplaces of globular clusters, we present a careful examination of the formation of self-gravitating gas clouds within assembling dark matter haloes in a hierarchical cosmological model. Our high-resolution smoothed particle hydrodynamical simulations are designed to determine whether or not hypothesized supergiant molecular clouds (SGMCs) form and, if they do, to determine their physical properties and mass spectra. It was suggested in earlier work that clouds with a median mass of several 10^8 M_sun are expected to assemble during the formation of a galaxy, and that globular clusters form within these SGMCs. Our simulations show that clouds with the predicted properties are indeed produced as smaller clouds collide and agglomerate within the merging dark matter haloes of our cosmological model. We find that the mass spectrum of these clouds obeys the same power-law form observed for globular clusters, molecular clouds, and their internal clumps in galaxies, and predicted for the supergiant clouds in which globular clusters may form. We follow the evolution and physical properties of gas clouds within small dark matter haloes up to z = 1, after which prolific star formation is expected to occur. Finally, we discuss how our results may lead to more physically motivated "rules" for star formation in cosmological simulations of galaxy formation.Comment: Accepted to The Astrophysical Journal; 17 pages, 8 figure

Painleve versus Fuchs

The sigma form of the Painlev{\'e} VI equation contains four arbitrary parameters and generically the solutions can be said to be genuinely ``nonlinear'' because they do not satisfy linear differential equations of finite order. However, when there are certain restrictions on the four parameters there exist one parameter families of solutions which do satisfy (Fuchsian) differential equations of finite order. We here study this phenomena of Fuchsian solutions to the Painlev{\'e} equation with a focus on the particular PVI equation which is satisfied by the diagonal correlation function C(N,N) of the Ising model. We obtain Fuchsian equations of order $N+1$ for C(N,N) and show that the equation for C(N,N) is equivalent to the $N^{th}$ symmetric power of the equation for the elliptic integral $E$. We show that these Fuchsian equations correspond to rational algebraic curves with an additional Riccati structure and we show that the Malmquist Hamiltonian $p,q$ variables are rational functions in complete elliptic integrals. Fuchsian equations for off diagonal correlations $C(N,M)$ are given which extend our considerations to discrete generalizations of Painlev{\'e}.Comment: 18 pages, Dedicated to the centenary of the publication of the Painleve VI equation in the Comptes Rendus de l'Academie des Sciences de Paris by Richard Fuchs in 190

Star Formation, Supernovae Feedback and the Angular Momentum Problem in Numerical CDM Cosmogony: Half Way There?

We present a smoothed particle hydrodynamic (SPH) simulation that reproduces a galaxy that is a moderate facsimile of those observed. The primary failing point of previous simulations of disk formation, namely excessive transport of angular momentum from gas to dark matter, is ameliorated by the inclusion of a supernova feedback algorithm that allows energy to persist in the model ISM for a period corresponding to the lifetime of stellar associations. The inclusion of feedback leads to a disk at a redshift $z=0.52$, with a specific angular momentum content within 10% of the value required to fit observations. An exponential fit to the disk baryon surface density gives a scale length within 17% of the theoretical value. Runs without feedback, with or without star formation, exhibit the drastic angular momentum transport observed elsewhere.Comment: 4 pages, 3 figures, accepted for publication in ApJ Letter