5,806 research outputs found
Seasonal Flight Patterns of Miridae (Hemiptera) in a Southern Illinois Black Walnut Plantation
The seasonal flight patterns of 92 species of Miridae collected in window traps in a southern Illinois black walnut plantation are compared with similar data from a North Carolina black walnut plantation. Flying height distributions and seasonal flight activities of Amblytylus nasutus, Deraeocoris nebulosus, Leptopterna dolabrata, Lopidea heidemanni, Lygus lineolaris, and Plagiognathus politus are considered in detail. Six species are newly recorded for Illinois
Ionic Liquids in Dye Sensitized Solar Cells : Theoretical Assessment of Properties and Applications
Dye-sensitized solar cells have the potential to play a major role in the future of the global energy economy. Unfortunately, they still lack the consistency and durability to be truly competitive from a commercial point of view. The use of ionic liquids may hold a solution to most of the current drawbacks; thus, the implications of their use in dye-sensitized solar cells are approached by means of quantum chemical calculations and computational modeling. The pure bulk phase of three promising cyano-based ionic liquids was investigated by ab initio molecular dynamics studies. Differences in cation-cation structuring was revealed despite the fact that all liquids bear the same cation, which might be correlated to macroscopic properties such as viscosity. The semiconductor-electrolyte interface is of special interest, as many processes occur here in a complete device. Characterization of this system was attempted on different pathways: First, the adsorption behavior was investigated in detail for selected cyano-based ionic liquids in order to understand specific interactions. Second, a polarizable molecular dynamics force field was parametrized to study the extended TiO2-ionic liquid interface, focusing on cooperative and bulk phase effects. Third, a great variety of ionic liquids were classified in their ability to shift the energy levels of the semiconductor TiO2. Furthermore, influences of the ionic liquid electrolyte on the sensitizing dye were studied. Directed coordination plays a role, and a universal redshift of adsorption spectra upon solvation with respect to the gas phase is apparent. Beneficial effects of ionic liquid application can be fine-tuning of semiconductor energy levels or spectroscopic properties of the dye, they can build blocking layers on the surface to prevent unfavored recombination reactions, or can enhance dye regeneration by favorably interacting with the redox mediator. Ultimately, the choice of the ionic liquid decides. Choosing the "right" ionic liquid can certainly have beneficial effects on the dye-sensitized solar cell, whereas choosing the "wrong" ionic liquid will result in inferior properties. By illuminating the fundamental processes involved, the results presented herein shall guide the choice of the ionic liquid electrolyte in future applications
The Bates Student - volume 104 number 13 - October 6, 1977
The seasonal flight patterns of 79 species of Miridae collected in window traps in a North Carolina black walnut plantation are described. Flying height distributions and seasonal flight activities of Deraeocoris nebulosus (Uhler), Keltonia sulphurea (Reuter), Lygus lineolaris (Palisot de Beauvois), Plagiognathus politus Uhler, and Reuteroscopus ornatus (Reuter) are considered in detail
Alumnae Bulletin - Number 3
Greetings to Alumnae Members and Graduates
Alumnae Officers
Membership
Financial Statement as of 3-1-37
Sick Committee
Are You?
Alumnae Days
Were You at the Bazaar?
History of the Nurses\u27 Relief Fund
Forget-Me-Not
In Memoriam
Here and There
Marriages Reported During 1936-1937
A Resume
Student Nurse Activity
Jefferson Nurses Choral Club
The Bulletin - Publicity Committee
Do You Know?
Bazaar Accoun
Chemotherapeutic drugs sensitize human renal cell carcinoma cells to ABT-737 by a mechanism involving the Noxa-dependent inactivation of Mcl-1 or A1
<p>Abstract</p> <p>Background</p> <p>Human renal cell carcinoma (RCC) is very resistant to chemotherapy. ABT-737 is a novel inhibitor of anti-apoptotic proteins of the Bcl-2 family that has shown promise in various preclinical tumour models.</p> <p>Results</p> <p>We here report a strong over-additive pro-apoptotic effect of ABT-737 and etoposide, vinblastine or paclitaxel but not 5-fluorouracil in cell lines from human RCC. ABT-737 showed very little activity as a single agent but killed RCC cells potently when anti-apoptotic Mcl-1 or, unexpectedly, A1 was targeted by RNAi. This potent augmentation required endogenous Noxa protein since RNAi directed against Noxa but not against Bim or Puma reduced apoptosis induction by the combination of ABT-737 and etoposide or vinblastine. At the level of mitochondria, etoposide-treatment had a similar sensitizing activity and allowed for ABT-737-induced release of cytochrome <it>c</it>.</p> <p>Conclusions</p> <p>Chemotherapeutic drugs can overcome protection afforded by Mcl-1 and A1 through endogenous Noxa protein in RCC cells, and the combination of such drugs with ABT-737 may be a promising strategy in RCC. Strikingly, A1 emerged in RCC cell lines as a protein of similar importance as the well-established Mcl-1 in protection against apoptosis in these cells.</p
Information Technology-Enabled Transformation: Research That Bridges the Functional Divide
The field of information systems can do more to clarify the significance of its research in relation to other management disciplines. Few external stakeholders, including faculty in other fields, deans, practitioners, senior managers, and policy makers, are able to identify common topics in IS research, and fewer still know what it is that draws IS researchers to a particular problem or an unexplained phenomenon. This panel considers the proposition that understanding IT-driven transformations is one of the core themes of the IS research field. The panel focuses on the role that research on IT-enabled transformations can play in offering a compelling story about the field and its scholarly and practical contributions. Because IT-enabled transformations inevitably influence and are influenced by a range of environmental and contextual factors, these phenomena cannot be examined in isolation and must necessarily draw upon theories and insights developed in other functional disciplines. Transformations are non- incremental, leap-frogging advances in the use of IT that reshape markets, radically alter cost structures, and lead to entirely new digital products. Focusing on the role of research in knowing what gives rise to IT-enabled transformations (and how various players and organizations will succeed or are disrupted) bridges the different areas of IS research, and offers the most compelling story about our field to those outside it
Storm
A immitation of Nature.The following is the idea conveyed by this Composition: A Shepherd is going home with his flock. While he is playing an air on his flute, a storm approaches; the thunder; the roaring of the water; the crash of trees, and the firebells are to be heard in succession.N.B.1 marks the loud Pedal which is to be held down throughout the piece; 2 marks the soft Pedal from which the foot is to be taken, when that figure is encirceld as: (2) On the judicious management of the soft Pedal in connection with the loud Pedal, the effect of this piece mainly depends. Care should be taken to commence the thunder softly without playing the tones distinctly
Electronic Commerce in the Retail Brokerage Industry: Trading Costs of Internet Versus Full Service Firms
Electronic brokerages on the Internet represent one of the most successful examples of
electronic commerce, having captured over 20% of retail stock trades. According to
economic theory, prices of commodities like securities should converge to one price in a
market with the transparency of the Internet. A review of published commissions for
online brokers shows that this "law of one price" does not appear to hold for the
commissions charged by retail brokers. In this paper we explore one possible explanation
for these differences in commissions. Specifically, we test whether the total cost of
trading, including commissions and savings based on the quality of execution, obeys the
law of one price. In a carefully designed experiment, we simultaneously purchased or
sold 100 share lots of stock using a voice-broker, an expensive online broker and an
inexpensive online broker in each trial. We found relatively few price improvements,
which are a measure of execution quality. The difference among brokers in obtaining
price improvements was not statistically significant. The brokers do exhibit statistically
significant differences in total trading costs; at a volume of 100 shares commission costs
dominate execution quality. We explore the implications of the findings for larger lot
sizes, choosing a broker, and electronic commerce in the brokerage industry.Information Systems Working Papers Serie
- …