Analgesic action of laser therapy (LLLT) in an animal model

Objectives: To evaluate the analgesic effect of laser therapy on healthy tissue of mice. Study design: Forty-five animals were divided in three groups of 15: A ? infrared laser irradiation (830 nm, Kondortech®, São Carlos, SP, Brazil); B ? red laser irradiation (660 nm, Kondortech®, São Carlos, SP, Brazil); C ? sham irradiation with laser unit off. After laser application, the mice remained immobilized for the injection of 30 µl of 2% formalin in the plantar pad of the irradiated hind paw. The time that the mouse kept the hind paw lifted was measured at 5 min intervals for 30 minutes. Results: Results showed statistically significant differences comparing the control group with the infrared laser group at 5, 20, 25 and 30 accumulated minutes, and with the red laser group at all time points. The analysis of partial times, at each 5 minutes, showed statistically significant differences between the control and the laser groups up to 20 minutes. Conclusions: Laser therapy had an analgesic effect and red laser had the best results

Effect of three different protocols of low-level laser therapy on thyroid hormone production after dental implant placement in an experimental rabbit model

Objective: The purpose of this study was to assess the systemic effects of low-level laser therapy (LLLT) on thyroid gland function and, consequently, calcium regulation – as measured by serum triiodothyronine (T3), thyroxine (T4), and free calcium levels – when administered after dental implant placement in a rabbit model. Background data: Protocols for the use of laser therapy in several clinical procedures are currently under investigation, as not all of the actions and systemic effects of laser irradiation have been clearly established. Materials and methods: Forty male adult New Zealand rabbits were distributed across five groups of eight animals each: two control groups (C-I and C-II) of unirradiated animals, and three experimental groups (E-5, E- 10, and E-20), each exposed to a distinct dose of gallium-aluminum-arsenide (GaAlAs) laser [λ = 830 nm2, 50 mW, continuous wave (CW)] every 48 h for a total of seven sessions. The total dose per session was 5 J/cm2 in E-5, 10 J/cm² in E-10, and 20 J/cm² in E-20. Animals in C-II and all experimental groups underwent surgical extraction of the mandibular left incisor followed by immediate placement of an osseointegrated implant (Nanotite® , Biomet 3iTM) into the socket. Animals in group C-I served as an absolute control for T3, T4, and calcium measurements. The level of significance was set at 5% ( p ≤ 0.05). Results: ANOVA with Tukey’s posthoc test revealed significant differences in T3 and calcium levels among experimental groups, as well as significant within-group differences in T3, T4, and calcium levels over time. Conclusions: Although not reaching abnormal values, LLLT applied to the mandible influenced thyroid function in this mode

Avaliação da ancoragem de implantes dentários irradiados com laser GaAlAs (830 nm)

The aim of the present study was to evaluate titanium implants fixed with free rotation in rabbit’s tibia and irradiated with GaAlAs laser (4.3Joules/daily, 830nm wavelength, 12mW and 51 seconds) using a digital torquimeter. Thirty male rabbits were divided into two groups (Laser and Control) and subdivided according to their death day 15 (L1 and C1), 30 (L2 and C2) and 45 (L3 and C3) after surgery. A digital torquimeter evaluated the torque needed for removing the implants, breaking their union to the bone. The results were submitted to Student’s “t” test and ANOVA test, in order to validate these findings. It was observed an increase on removal torque values of irradiated implants both with 15 and 30 days after surgery, in comparison to control groups. With 45 days, there was no statistically significant difference between the Laser and Control groups values. It was concluded that Laser group showed a higher value in the removal torque when compared to non-irradiated implants.O objetivo desta pesquisa foi avaliar, através do uso de um torquímetro digital, se implantes de titânio, instalados com liberdade rotaciona em tíbias de coelhos e irradiados com laser de Arseneto de Gálio e Alumínio, na dose de 86 J/cm2, com comprimento de onda de 830 nm, potência de 12 mW e tempo de aplicação de 51 segundos, apresentam um valor de torque de remoção estatisticamente maior que os valores obtidos nos grupos não irradiados (grupo controle). Para tanto, trabalhou-se com trinta coelhos, da raça Nova Zelândia, machos, os quais foram divididos em dois grupos, Laser e Controle, e subdivididos de acordo com o dia de sua morte. Os grupos L1 e C1, L2 e C2, L3 e C3 foram mortos 15, 30 e 45 dias após a inserção do implante, respectivamente. Um torquímetro digital mensurou o torque necessário para o afrouxamento do implante, rompendo sua união com o osso. Os resultados foram, então, submetidos ao Teste “t” de Student e ao Teste ANOVA, a fim de validar esses achados. Observou-se, para um p=0,05, um aumento nos valores dos torques de remoção dos implantes irradiados com laser e controle (L1 e L2), tanto aos quinze quanto aos trinta dias após as cirurgias, em relação aos respectivos grupos controle (C1 e C2). Aos 45 dias, não mais foi observada diferença estatisticamente significante entre os valores encontrados nos grupos laser e controle (L1 e C1). Concluiu-se, nesse modelo animal e com o protocolo de irradiação utilizado neste estudo, que o laser, por ser a única variável entre os grupos, foi responsável pelo aumento do embricamento do implante ao osso, no mês inicial e mais critico da osseointegração

Intervenção cirúrgica combinada com a terapia antibiótica na osteomielite mandibular crônica: estudo de caso

Chronic osteomyelitis of the mandible is usually a difficult pathology to resolve. Treatment has included long-term antibiotics, and surgical debridement, aggressive in some cases. This paper reports a 54-year-old female with an eight-month-mandibular chronic osteomyelitis who was successfully treated with the combination of medication and surgical intervention.A osteomielite crônica da mandíbula geralmente apresenta-se como uma patologia de difícil tratamento, necessitando de terapia antibiótica de longa duração e intervenção cirúrgica, por vezes agressiva. No presente estudo, relata-se uma paciente do gênero feminino de 54 anos, acometida por osteomielite crônica da mandíbula há oito meses, que foi tratada com sucesso através da associação medicamentosa com o tratamento cirúrgico